PL384756A1 - Sposób wytwarzania stabilnej kompozycji orlistatu w postaci kapsułkowanego proszku - Google Patents
Sposób wytwarzania stabilnej kompozycji orlistatu w postaci kapsułkowanego proszkuInfo
- Publication number
- PL384756A1 PL384756A1 PL384756A PL38475608A PL384756A1 PL 384756 A1 PL384756 A1 PL 384756A1 PL 384756 A PL384756 A PL 384756A PL 38475608 A PL38475608 A PL 38475608A PL 384756 A1 PL384756 A1 PL 384756A1
- Authority
- PL
- Poland
- Prior art keywords
- stable
- production method
- encapsulated powder
- orlistat
- composition
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- AHLBNYSZXLDEJQ-FWEHEUNISA-N orlistat Chemical compound CCCCCCCCCCC[C@H](OC(=O)[C@H](CC(C)C)NC=O)C[C@@H]1OC(=O)[C@H]1CCCCCC AHLBNYSZXLDEJQ-FWEHEUNISA-N 0.000 title 1
- 229960001243 orlistat Drugs 0.000 title 1
- 239000000843 powder Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4833—Encapsulating processes; Filling of capsules
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL384756A PL216542B1 (pl) | 2008-03-20 | 2008-03-20 | Sposób wytwarzania stabilnej kompozycji orlistatu w postaci kapsułkowanego proszku |
| EP09721857.2A EP2268266B1 (en) | 2008-03-20 | 2009-03-19 | Process for obtaining powder compositions of orlistat to be filled into a capsule |
| PCT/PL2009/000025 WO2009116880A2 (en) | 2008-03-20 | 2009-03-19 | Process for obtaining powder compositions of orlistat |
| ES09721857T ES2836736T3 (es) | 2008-03-20 | 2009-03-19 | Proceso para obtener composiciones en polvo de Orlistat para ser llenadas en una cápsula |
| US12/933,227 US20110045085A1 (en) | 2008-03-20 | 2009-03-19 | Process for obtaining powder compositions of orlistat |
| EA201071103A EA201071103A1 (ru) | 2008-03-20 | 2009-03-19 | Способ получения порошковых композиций орлистата |
| PT97218572T PT2268266T (pt) | 2008-03-20 | 2009-03-19 | Processo para obter composições em pó de orlistat a serem preenchidas numa cápsula |
| DK09721857.2T DK2268266T3 (da) | 2008-03-20 | 2009-03-19 | Fremgangsmåde til opnåelse af pulversammensætninger af orlistat, der skal fyldes i en kapsel |
| EP20160560.7A EP3682869A1 (en) | 2008-03-20 | 2009-03-19 | Process for obtaining powder compositions of orlistat |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL384756A PL216542B1 (pl) | 2008-03-20 | 2008-03-20 | Sposób wytwarzania stabilnej kompozycji orlistatu w postaci kapsułkowanego proszku |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL384756A1 true PL384756A1 (pl) | 2009-09-28 |
| PL216542B1 PL216542B1 (pl) | 2014-04-30 |
Family
ID=41055345
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL384756A PL216542B1 (pl) | 2008-03-20 | 2008-03-20 | Sposób wytwarzania stabilnej kompozycji orlistatu w postaci kapsułkowanego proszku |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20110045085A1 (pl) |
| EP (2) | EP2268266B1 (pl) |
| DK (1) | DK2268266T3 (pl) |
| EA (1) | EA201071103A1 (pl) |
| ES (1) | ES2836736T3 (pl) |
| PL (1) | PL216542B1 (pl) |
| PT (1) | PT2268266T (pl) |
| WO (1) | WO2009116880A2 (pl) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0901602B8 (pt) * | 2009-04-03 | 2021-05-25 | Ems S/A | formulação farmacêuticas |
| UA107369C2 (en) * | 2010-02-01 | 2014-12-25 | Lab Bago S A | Pharmaceutical composition with anti-obesity activity comprising a premixture of pure orlistat and preparation process |
| WO2012082083A1 (en) * | 2010-12-15 | 2012-06-21 | Les Laboratoires Medis Sa | Pharmaceutical formulation containing tetrahydrolipstatin as an active ingredient |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6471994B1 (en) * | 1995-01-09 | 2002-10-29 | Edward Mendell Co., Inc. | Pharmaceutical excipient having improved compressibility |
| US6004996A (en) | 1997-02-05 | 1999-12-21 | Hoffman-La Roche Inc. | Tetrahydrolipstatin containing compositions |
| TR200100471T2 (tr) | 1998-08-14 | 2001-07-23 | F.Hoffmann-La Roche Ag | Lipaz inhibitörleri içeren farmasötik bileşimler |
| AR025587A1 (es) | 1999-09-13 | 2002-12-04 | Hoffmann La Roche | Formulaciones en dispersion que contienen inhibidores de lipasa |
| AR025609A1 (es) | 1999-09-13 | 2002-12-04 | Hoffmann La Roche | Formulaciones lipidas solidas |
| US20030180352A1 (en) * | 1999-11-23 | 2003-09-25 | Patel Mahesh V. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| DE10021618A1 (de) | 2000-05-04 | 2001-11-15 | Volker Helmstaedter | Präparat für Darmerkrankungen und dessen Verwendung |
| PL203804B1 (pl) | 2000-06-27 | 2009-11-30 | Hoffmann La Roche | Sposób wytwarzania kompozycji farmaceutycznej w postaci spoistej, płytkowej, piankowej, gąbczastej lub ciastowatej struktury i kompozycja farmaceutyczna otrzymana tym sposobem |
| RU2241462C2 (ru) | 2000-07-28 | 2004-12-10 | Ф. Хоффманн-Ля Рош Аг | Новая фармацевтическая композиция |
| US6730319B2 (en) | 2001-06-06 | 2004-05-04 | Hoffmann-La Roche Inc. | Pharmaceutical compositions having depressed melting points |
| US20030027786A1 (en) | 2001-06-06 | 2003-02-06 | Karsten Maeder | Lipase inhibiting composition |
| EP1470116A4 (en) * | 2001-12-04 | 2005-04-06 | Biogal Gyogyszergyar | PREPARATION OF THE ORLISTAT AND CRYSTALLINE FORMS OF THE ORLISTAT |
| US8372430B2 (en) * | 2002-12-17 | 2013-02-12 | The Procter & Gamble Company | Compositions, methods, and kits useful for the alleviation of gastrointestinal effects |
| US7485322B2 (en) * | 2002-12-24 | 2009-02-03 | Lek Pharmaceuticals D.D. | Modified release pharmaceutical composition |
| CL53426B (pl) * | 2007-08-06 | 2016-11-28 | ||
| EA201070378A1 (ru) | 2007-09-17 | 2010-08-30 | Др. Редди`С Лабораторис Лтд. | Фармацевтические составы орлистата |
| WO2009044380A2 (en) | 2007-10-05 | 2009-04-09 | Ranbaxy Laboratories Limited | Formulations containing orlistat particles having controlled particle size |
-
2008
- 2008-03-20 PL PL384756A patent/PL216542B1/pl unknown
-
2009
- 2009-03-19 US US12/933,227 patent/US20110045085A1/en not_active Abandoned
- 2009-03-19 EP EP09721857.2A patent/EP2268266B1/en active Active
- 2009-03-19 WO PCT/PL2009/000025 patent/WO2009116880A2/en not_active Ceased
- 2009-03-19 DK DK09721857.2T patent/DK2268266T3/da active
- 2009-03-19 PT PT97218572T patent/PT2268266T/pt unknown
- 2009-03-19 ES ES09721857T patent/ES2836736T3/es active Active
- 2009-03-19 EP EP20160560.7A patent/EP3682869A1/en not_active Withdrawn
- 2009-03-19 EA EA201071103A patent/EA201071103A1/ru unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009116880A2 (en) | 2009-09-24 |
| DK2268266T3 (da) | 2020-11-02 |
| PT2268266T (pt) | 2020-12-18 |
| EP2268266A2 (en) | 2011-01-05 |
| EP2268266B1 (en) | 2020-10-21 |
| EA201071103A1 (ru) | 2011-02-28 |
| EP3682869A1 (en) | 2020-07-22 |
| PL216542B1 (pl) | 2014-04-30 |
| ES2836736T3 (es) | 2021-06-28 |
| US20110045085A1 (en) | 2011-02-24 |
| WO2009116880A3 (en) | 2009-12-10 |
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