PL389665A1 - Wytwarzanie biopaliwa przez rekombinowane mikroorganizmy - Google Patents

Wytwarzanie biopaliwa przez rekombinowane mikroorganizmy

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Publication number
PL389665A1
PL389665A1 PL389665A PL38966508A PL389665A1 PL 389665 A1 PL389665 A1 PL 389665A1 PL 389665 A PL389665 A PL 389665A PL 38966508 A PL38966508 A PL 38966508A PL 389665 A1 PL389665 A1 PL 389665A1
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PL
Poland
Prior art keywords
bio
fuel
production
recombinant microorganisms
microorganisms
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Application number
PL389665A
Other languages
English (en)
Inventor
James C. Liao
Shota Atsumi
Kevin M. Smith
Roa Pu Claire Shen
Anthony F. Cann
Michael R. Connor
Original Assignee
The Regents of the University of CaliforniaThe Regents of the University of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by The Regents of the University of CaliforniaThe Regents of the University of California filed Critical The Regents of the University of CaliforniaThe Regents of the University of California
Publication of PL389665A1 publication Critical patent/PL389665A1/pl

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    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/16Butanols
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    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
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    • C12N15/52Genes encoding for enzymes or proenzymes
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    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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    • C12N9/1025Acyltransferases (2.3)
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    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/1029Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
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    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
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    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06Ethanol, i.e. non-beverage
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    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/22Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
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    • C12Y101/00Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01001Alcohol dehydrogenase (1.1.1.1)
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    • C12Y101/01Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/010853-Isopropylmalate dehydrogenase (1.1.1.85)
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    • C12Y101/01Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01086Ketol-acid reductoisomerase (1.1.1.86)
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    • C12Y202/00Transferases transferring aldehyde or ketonic groups (2.2)
    • C12Y202/01Transketolases and transaldolases (2.2.1)
    • C12Y202/01006Acetolactate synthase (2.2.1.6)
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    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/01Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01182(R)-Citramalate synthase (2.3.1.182)
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    • C12YENZYMES
    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/03Acyl groups converted into alkyl on transfer (2.3.3)
    • C12Y203/030132-Isopropylmalate synthase (2.3.3.13)
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    • C12YENZYMES
    • C12Y401/00Carbon-carbon lyases (4.1)
    • C12Y401/01Carboxy-lyases (4.1.1)
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    • C12Y402/00Carbon-oxygen lyases (4.2)
    • C12Y402/01Hydro-lyases (4.2.1)
    • C12Y402/01009Dihydroxy-acid dehydratase (4.2.1.9), i.e. acetohydroxyacid dehydratase
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    • C12Y402/00Carbon-oxygen lyases (4.2)
    • C12Y402/01Hydro-lyases (4.2.1)
    • C12Y402/01019Imidazoleglycerol-phosphate dehydratase (4.2.1.19)
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    • C12Y402/00Carbon-oxygen lyases (4.2)
    • C12Y402/01Hydro-lyases (4.2.1)
    • C12Y402/010333-Isopropylmalate dehydratase (4.2.1.33)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/10Biofuels, e.g. bio-diesel

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Liquid Carbonaceous Fuels (AREA)
PL389665A 2007-02-09 2008-02-08 Wytwarzanie biopaliwa przez rekombinowane mikroorganizmy PL389665A1 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US90047707P 2007-02-09 2007-02-09
US90054607P 2007-02-09 2007-02-09
US92192707P 2007-04-04 2007-04-04
US95663407P 2007-08-17 2007-08-17

Publications (1)

Publication Number Publication Date
PL389665A1 true PL389665A1 (pl) 2010-07-05

Family

ID=39682457

Family Applications (1)

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PL389665A PL389665A1 (pl) 2007-02-09 2008-02-08 Wytwarzanie biopaliwa przez rekombinowane mikroorganizmy

Country Status (12)

Country Link
US (2) US8975049B2 (pl)
EP (1) EP2118266A4 (pl)
JP (1) JP2011510611A (pl)
KR (1) KR20090117739A (pl)
CN (2) CN103540559A (pl)
AU (1) AU2008212799A1 (pl)
BR (1) BRPI0807235A2 (pl)
CA (1) CA2678261A1 (pl)
MX (1) MX2009008416A (pl)
MY (1) MY147186A (pl)
PL (1) PL389665A1 (pl)
WO (1) WO2008098227A2 (pl)

Families Citing this family (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8945899B2 (en) 2007-12-20 2015-02-03 Butamax Advanced Biofuels Llc Ketol-acid reductoisomerase using NADH
EP3301182B1 (en) 2005-10-26 2020-03-18 Butamax (TM) Advanced Biofuels LLC Fermentative production of four carbon alcohols
US9303225B2 (en) 2005-10-26 2016-04-05 Butamax Advanced Biofuels Llc Method for the production of isobutanol by recombinant yeast
EP2102327A4 (en) * 2006-12-01 2010-01-06 Gevo Inc MANIPULATED MICROORGANISMS FOR THE MANUFACTURE OF N-BUTANOL AND CORRESPONDING METHODS
WO2008109122A1 (en) * 2007-03-05 2008-09-12 Novus Energy, Llc Efficient use of biogas carbon dioxie in liquid fuel synthesis
TWI568847B (zh) * 2007-03-16 2017-02-01 奇諾麥提卡公司 用於1,4-丁二醇及其前驅物之生物合成的組合物及方法
WO2008130995A2 (en) * 2007-04-18 2008-10-30 E. I. Du Pont De Nemours And Company Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes
CN101903530A (zh) * 2007-10-12 2010-12-01 加利福尼亚大学董事会 被改造以产生异丙醇的微生物
US8431374B2 (en) * 2007-10-31 2013-04-30 Gevo, Inc. Methods for the economical production of biofuel from biomass
US8114641B2 (en) 2007-12-10 2012-02-14 Synthetic Genomics, Inc. Methylbutanol as an advanced biofuel
US10093552B2 (en) 2008-02-22 2018-10-09 James Weifu Lee Photovoltaic panel-interfaced solar-greenhouse distillation systems
US9259662B2 (en) 2008-02-22 2016-02-16 James Weifu Lee Photovoltaic panel-interfaced solar-greenhouse distillation systems
AU2009217293B2 (en) 2008-02-23 2014-11-20 James Weifu Lee Designer organisms for photobiological butanol production from carbon dioxide and water
US8986963B2 (en) * 2008-02-23 2015-03-24 James Weifu Lee Designer calvin-cycle-channeled production of butanol and related higher alcohols
EP3450550A1 (en) * 2008-03-05 2019-03-06 Genomatica, Inc. Primary alcohol producing organisms
AU2009256209A1 (en) * 2008-06-04 2009-12-10 Butamax(Tm) Advanced Biofuels Llc Deletion mutants for the production of isobutanol
US20110281314A1 (en) * 2008-08-04 2011-11-17 Lynch Michael D Methods, systems and compositions related to microbial bio-production of butanol and/or isobutanol
WO2010031772A2 (en) * 2008-09-16 2010-03-25 Dsm Ip Assets B.V. Alternative butanol production process in a microbial cell
US20100081154A1 (en) 2008-09-29 2010-04-01 Butamax(Tm) Advanced Biofuels Llc IDENTIFICATION AND USE OF BACTERIAL [2Fe-2S] DIHYDROXY-ACID DEHYDRATASES
AU2009296224B2 (en) * 2008-09-29 2015-02-12 Butamax(Tm) Advanced Biofuels Llc Increased heterologous Fe-S enzyme actiivty in yeast
AU2009296232A1 (en) * 2008-09-29 2010-04-01 Butamax(Tm) Advanced Biofuels Llc Enhanced iron-sulfur cluster formation for increased dihydroxy-acid dehydratase activity in lactic acid bacteria
BRPI0913681A2 (pt) * 2008-09-29 2019-09-24 Butamax Advanced Biofuels Llc "célula bacteriana ácido-lática recombinante e método de produção de isobutanol"
AU2009296227A1 (en) * 2008-09-29 2010-04-01 Butamax(Tm) Advanced Biofuels Llc Enhanced pyruvate to 2,3-butanediol conversion in lactic acid bacteria
BRPI0919696A2 (pt) 2008-10-18 2015-08-04 Univ California Polipeptídeo substancialmente purificado, microorganismo recombinante, e, polinucleotídeo isolado.
AU2009320163B2 (en) * 2008-10-27 2014-10-02 Butamax(Tm) Advanced Biofuels Llc Carbon pathway optimized production hosts for the production of isobutanol
WO2010051527A2 (en) 2008-10-31 2010-05-06 Gevo, Inc. Engineered microorganisms capable of producing target compounds under anaerobic conditions
US8124400B2 (en) * 2008-12-10 2012-02-28 Synthetic Genomics, Inc. Production of branched-chain alcohols by photosynthetic microorganisms
WO2010071851A2 (en) * 2008-12-20 2010-06-24 The Regents Of University Of California Conversion of co2 to higher alcohols using photosysnthetic microorganisms
EP2379730B1 (en) * 2008-12-31 2015-07-22 Metabolic Explorer Method for the preparation of diols
TW201037078A (en) * 2009-03-11 2010-10-16 Dsm Ip Assets Bv Preparation of alpha-ketopimelic acid
JP5698655B2 (ja) * 2009-03-30 2015-04-08 公益財団法人地球環境産業技術研究機構 コリネ型細菌形質転換体及びそれを用いるイソブタノールの製造方法
US8232089B2 (en) * 2009-08-12 2012-07-31 Gevo, Inc. Cytosolic isobutanol pathway localization for the production of isobutanol
US8715971B2 (en) * 2009-09-09 2014-05-06 Genomatica, Inc. Microorganisms and methods for the co-production of isopropanol and 1,4-butanediol
WO2011037598A1 (en) * 2009-09-25 2011-03-31 The Regents Of The University Of California Conversion of co2 to higher alcohols using recombinant photosynthetic microorganisms
WO2011057288A2 (en) * 2009-11-09 2011-05-12 The Regents Of The University Of California Isobutanol production with corynebacterium glutamicum
GB2487889B (en) 2009-11-24 2012-12-19 Gevo Inc Methods of increasing dihydroxy acid dehydratase activity to improve production of fuels, chemicals, and amino acids
EP2519628A2 (en) 2009-12-29 2012-11-07 Butamax (TM) Advanced Biofuels LLC Alcohol dehydrogenases (adh) useful for fermentive production of lower alkyl alcohols
US8530221B2 (en) 2010-01-14 2013-09-10 Ls9, Inc. Production of branched chain fatty acids and derivatives thereof in recombinant microbial cells
WO2011088425A2 (en) 2010-01-15 2011-07-21 The Regents Of The University Of California Electro-autotrophic synthesis of higher alcohols
EP2534240B1 (en) * 2010-02-12 2019-06-05 GEVO, Inc. Yeast microorganisms with reduced by-product accumulation for improved production of fuels, chemicals, and amino acids
KR20130027063A (ko) 2010-02-17 2013-03-14 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 Fe-s 클러스터 요구성 단백질의 활성 향상
WO2011106576A2 (en) * 2010-02-24 2011-09-01 Qteros, Inc. Methods and compositions for enhanced enzyme activity in fermenting microorganisms
US9193965B2 (en) * 2010-04-27 2015-11-24 The Regents Of The University Of California Acetolactate synthase having 2-ketoisovalerate decarboxylase activity and uses thereof
JP5056897B2 (ja) 2010-05-14 2012-10-24 トヨタ自動車株式会社 2−ブタノールの製造方法及び2−ブタノール生産能を有する組換え微生物
TWI500768B (zh) * 2010-07-05 2015-09-21 Metabolic Explorer Sa 由蔗糖製備1,3-丙二醇之方法
US8372610B2 (en) 2010-09-15 2013-02-12 Ls9, Inc. Production of odd chain fatty acid derivatives in recombinant microbial cells
US20110236941A1 (en) * 2010-10-22 2011-09-29 Lanzatech New Zealand Limited Recombinant microorganism and methods of production thereof
CA2810903A1 (en) * 2010-10-29 2012-05-03 Novozymes A/S Recombinant n-propanol and isopropanol production
US9284566B2 (en) 2010-11-03 2016-03-15 The Regents Of The University Of California Biofuel and chemical production by recombinant microorganisms via fermentation of proteinaceous biomass
US9493793B2 (en) 2010-11-22 2016-11-15 Cargill, Incorporated Compositions and methods for increased ethanol titer from biomass
KR101650883B1 (ko) * 2011-03-14 2016-08-24 이젤 바이오테크날러지스, 엘엘씨 알데하이드 및 상응하는 알콜의 미생물 합성 방법
US9790521B2 (en) 2011-03-24 2017-10-17 Butamax Advanced Biofuels Llc Host cells and methods for production of isobutanol
JP5813977B2 (ja) * 2011-03-30 2015-11-17 トヨタ自動車株式会社 Kluyveromyces属の変異体酵母及びこれを用いたエタノールの製造方法
JP2013005764A (ja) * 2011-06-24 2013-01-10 National Institute Of Advanced Industrial Science & Technology 大腸菌において混合糖から有機物質を生産する方法
WO2013003545A1 (en) * 2011-06-28 2013-01-03 Gevo, Inc. Tuning of fusel alcohol by-products during isobutanol production by recombinant microorganisms
KR101841261B1 (ko) * 2011-06-29 2018-05-08 한국과학기술원 개선된 프로판올 생성능을 가지는 변이 미생물 및 이를 이용한 프로판올의 제조방법
CN105473726B (zh) * 2011-07-28 2021-03-12 布特马斯先进生物燃料有限责任公司 酮异戊酸脱羧酶及其使用方法
CN107365733B (zh) * 2011-09-14 2021-08-17 基因组股份公司 在重组微生物细胞中制备奇数链脂肪酸衍生物
KR20140070605A (ko) 2011-09-16 2014-06-10 게노마티카 인코포레이티드 알켄을 생산하기 위한 유기체 및 방법
WO2014039060A1 (en) * 2011-10-07 2014-03-13 Gevo, Inc. Acetolactate synthases for improved metabolite production
WO2013055667A2 (en) * 2011-10-10 2013-04-18 Regents Of The University Of Minnesota Biocatalysis cells and methods
JP5803563B2 (ja) * 2011-10-24 2015-11-04 トヨタ自動車株式会社 イソブタノールの製造方法
CA2854450C (en) 2011-11-03 2020-04-21 Easel Biotechnologies, Llc Microbial production of n-butyraldehyde
EP2814970A4 (en) 2012-02-16 2016-03-02 Univ Columbia METHOD AND SYSTEMS FOR MANUFACTURING PRODUCTS WITH MANIPULATED SULFUR OXYGENATING BACTERIA
CN104302765B (zh) 2012-04-27 2018-09-11 赢创工业化学有限公司 反馈抗性α-异丙基苹果酸合酶
CA2873109A1 (en) 2012-05-11 2013-11-28 Butamax Advanced Biofuels Llc Ketol-acid reductoisomerase enzymes and methods of use
EP2877440A1 (en) * 2012-07-26 2015-06-03 Butamax Advanced Biofuels LLC Butanol purification
WO2014028642A1 (en) 2012-08-17 2014-02-20 Easel Biotechnologies, Llc Two stage production of higher alcohols
CN103667163B (zh) * 2012-09-04 2016-04-13 中国科学院天津工业生物技术研究所 生产异丁醇的重组微生物及方法
WO2014037912A2 (en) * 2012-09-07 2014-03-13 Cellworks Research India Pvt. Ltd Methods for production of isobutanol through nutrient stress and genetically modified microorganisms thereof
US9840724B2 (en) 2012-09-21 2017-12-12 Butamax Advanced Biofuels Llc Production of renewable hydrocarbon compositions
BR112015006691A2 (pt) 2012-09-26 2017-12-12 Butamax Advanced Biofuels Llc métodos, célula hospedeira recombinante, composição, polipeptídeo, polinucleotídeos e vetor recombinante
US9909150B2 (en) 2012-11-05 2018-03-06 Genomatica, Inc. Microorganisms and methods for enhancing the availability of reducing equivalents in the presence of methanol, and for producing 1,2-propanediol, n-propanol, 1,3-propanediol, or glycerol related thereto
CN103409332A (zh) * 2012-12-14 2013-11-27 北京工商大学 产β-苯乙醇的酿酒酵母工程菌构建、菌株及其应用
WO2014106107A2 (en) 2012-12-28 2014-07-03 Butamax (Tm) Advanced Biofuels Llc Dhad variants for butanol production
US9771602B2 (en) * 2013-03-15 2017-09-26 Butamax Advanced Biofuels Llc Competitive growth and/or production advantage for butanologen microorganism
WO2014151190A1 (en) 2013-03-15 2014-09-25 Butamax Advanced Biofuels Llc Dhad variants and methods of screening
CN104471771B (zh) * 2013-06-05 2018-12-07 中国科学院天津工业生物技术研究所 使用无细胞合成酶促通路将糖完全氧化成电能
WO2014198841A1 (en) * 2013-06-14 2014-12-18 Technical University Of Denmark 3hp tolerance
US9663759B2 (en) 2013-07-03 2017-05-30 Butamax Advanced Biofuels Llc Partial adaptation for butanol production
WO2015002916A1 (en) * 2013-07-03 2015-01-08 Butamax Advanced Biofuels Llc Post-transcriptional regulation of biosynthetic pathways
US9580758B2 (en) 2013-11-12 2017-02-28 Luc Montagnier System and method for the detection and treatment of infection by a microbial agent associated with HIV infection
CN104073508A (zh) * 2014-07-02 2014-10-01 浙江大学 一种提高大肠杆菌正丁醇耐受性的方法
WO2016181205A2 (en) * 2015-02-27 2016-11-17 Joule Unlimited Technologies, Inc. Controlled production of carbon-based products of interest
CN105002205B (zh) * 2015-07-29 2019-03-05 中国科学院广州能源研究所 一种高产异戊醇的基因工程菌及其构建方法和应用
CN106566794B (zh) * 2015-10-09 2020-05-01 中国科学院微生物研究所 产2-苯乙醇的基因工程菌及其应用方法
KR101747542B1 (ko) * 2015-10-23 2017-06-15 씨제이제일제당 (주) L-이소루신 생산능을 가지는 코리네박테리움 속 미생물 및 이를 이용하여 l-이소루신을 생산하는 방법
US20200308610A1 (en) 2016-03-11 2020-10-01 Aemitis, Inc. Alpha-ketoisocaproic acid and & alpha-keto-3-methylvaleric acid decarboxylases and uses thereof
BR112019000633A2 (pt) 2016-07-12 2019-07-09 Braskem Sa formação de alquenos através de desidratação enzimática de alcanóis
EP3519579B1 (en) * 2016-09-30 2025-11-05 Dow Global Technologies LLC Processes to prepare elongated 2-ketoacids and c-5-c10 compounds therefrom via genetic modifications to microbial metabolic pathways
BR112019013007A2 (pt) 2016-12-21 2019-10-08 Creatus Biosciences Inc organismo microbiano não natural, método de produção de um composto bioderivado, composto bioderivado e composição
KR102000755B1 (ko) 2016-12-27 2019-07-17 한국과학기술원 외부 유전자가 도입된 재조합 미생물 및 상기 미생물을 이용하여 개미산과 이산화탄소로부터 유용물질을 제조하는 방법
WO2018124475A2 (ko) * 2016-12-27 2018-07-05 한국과학기술원 외부 유전자가 도입된 재조합 미생물 및 상기 미생물을 이용하여 개미산과 이산화탄소로부터 유용물질을 제조하는 방법
CN108570437B (zh) * 2017-03-08 2021-03-16 中国科学院上海高等研究院 提升克雷伯氏肺炎杆菌生产异丁醇的方法及改造菌
US10808265B2 (en) 2018-09-26 2020-10-20 Nantbio, Inc. Microbes and methods for improved conversion of a feedstock
CN110438055B (zh) * 2019-08-01 2022-05-27 湖北大学 一种含有苯丙酮酸脱羧酶突变体的全细胞催化剂及在生产苯乙醇中的应用
JP7764852B2 (ja) 2019-09-25 2025-11-06 味の素株式会社 細菌の発酵による2-メチル酪酸の製造方法
CN114507608B (zh) * 2020-11-17 2023-08-22 中国科学院天津工业生物技术研究所 一种在线粒体内生产乙醇的重组丝状真菌及其构建和应用
US12595466B2 (en) 2020-03-06 2026-04-07 Gevo, Inc. NKR variants for increased production of isobutanol
CN111349644A (zh) * 2020-03-17 2020-06-30 花安堂生物科技集团有限公司 生物合成异戊二醇的菌株及方法
CN111349643B (zh) * 2020-03-17 2022-06-24 花安堂生物科技集团有限公司 生物合成异戊二醇的菌株及方法
CA3171681A1 (en) * 2020-03-18 2021-09-23 Fungmin Liew Fermentative production of 2-phenylethanol from gaseous substrates
US11788053B2 (en) 2020-06-15 2023-10-17 Melio Peptide Systems Inc. Microorganisms and methods for reducing bacterial contamination
JPWO2024096123A1 (pl) * 2022-11-04 2024-05-10
WO2025259581A2 (en) * 2024-06-10 2025-12-18 Massachusetts Institute Of Technology Microbial engineering for the production of alpha-substituted 3-hydroxy acids

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4424275A (en) * 1979-09-17 1984-01-03 Sidney Levy Continuous process for producing N-butanol employing anaerobic fermentation
US4551433A (en) 1981-05-18 1985-11-05 Genentech, Inc. Microbial hybrid promoters
US4568643A (en) * 1981-08-03 1986-02-04 Sidney Levy Continuous process for producing n-butanol employing anaerobic fermentation
US4520104A (en) 1982-11-18 1985-05-28 Cpc International Inc. Production of butanol by a continuous fermentation process
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
JPS61244723A (ja) 1985-04-12 1986-10-31 トキワ工業株式会社 シ−ラ−
JPS63102587A (ja) 1986-10-20 1988-05-07 Matsushita Electric Ind Co Ltd ビデオテツクス端末装置
JPS63102687A (ja) 1986-10-20 1988-05-07 Res Assoc Petroleum Alternat Dev<Rapad> ブタノ−ルの製造方法
AT388174B (de) 1987-03-10 1989-05-10 Vogelbusch Gmbh Verfahren zur vergaerung von kohlenhydrathaeltigen medien mit hilfe von bakterien
JPS63254986A (ja) 1987-04-10 1988-10-21 Res Assoc Petroleum Alternat Dev<Rapad> アルコ−ルの製造法
JPH084515B2 (ja) 1987-11-09 1996-01-24 出光興産株式会社 有機化合物の製造方法
US5000000A (en) 1988-08-31 1991-03-19 University Of Florida Ethanol production by Escherichia coli strains co-expressing Zymomonas PDC and ADH genes
US6015891A (en) 1988-09-09 2000-01-18 Mycogen Plant Science, Inc. Synthetic insecticidal crystal protein gene having a modified frequency of codon usage
US5192673A (en) 1990-04-30 1993-03-09 Michigan Biotechnology Institute Mutant strain of C. acetobutylicum and process for making butanol
US5210032A (en) * 1992-01-21 1993-05-11 Trustees Of The Boston University Degeneration-resistant solventogenic clostridia
US5426039A (en) 1993-09-08 1995-06-20 Bio-Rad Laboratories, Inc. Direct molecular cloning of primer extended DNA containing an alkane diol
US5908924A (en) * 1996-02-27 1999-06-01 Michigan State University Cloning and expression of the gene encoding thermoanaerobacter ethanolicus 39E secondary-alcohol dehydrogenase and enzyme biochemical characterization
WO1998051813A1 (en) 1997-05-14 1998-11-19 The Board Of Trustees Of The University Of Illinois A METHOD OF PRODUCING BUTANOL USING A MUTANT STRAIN OF $i(CLOSTRIDIUM BEIJERINCKII)
DE19907567B4 (de) 1999-02-22 2007-08-09 Forschungszentrum Jülich GmbH Verfahren zur mikrobiellen Herstellung von L-Valin
BRPI0014115B8 (pt) 1999-09-21 2021-05-25 Basf Ag métodos de produzir um panto-composto, pantotenato e beta-alanina, de aumentar a produção de um panto-composto e de edentificar compostos que modulam a atividade da pantotenato cinase, micro-organismo recombinante, vetor recombinante, e, vetor
EP1149918A1 (de) 2000-04-27 2001-10-31 Creavis Gesellschaft für Technologie und Innovation mbH Verfahren zur Oxidation von Kohlenwasserstoffen unter Verwendung von Mikroorganismen
EP1354955A4 (en) * 2000-12-28 2005-01-05 Toyota Motor Co Ltd PROCESS FOR PREPARING PRENYL ALCOHOL
JPWO2003095651A1 (ja) * 2002-05-10 2005-09-15 協和醗酵工業株式会社 メバロン酸の製造方法
CA2491145A1 (en) * 2002-07-03 2004-01-15 Basf Aktiengesellschaft Microorganisms and processes for enhanced production of pantothenate
AU2003253949A1 (en) * 2002-07-15 2004-02-02 Kosan Biosciences, Inc. Metabolic pathways for starter units in polyketide biosynthesis
WO2004044210A2 (en) * 2002-11-06 2004-05-27 University Of Florida Materials and methods for the efficient production of acetate and other products
FR2864967B1 (fr) * 2004-01-12 2006-05-19 Metabolic Explorer Sa Microorganisme evolue pour la production de 1,2-propanediol
JP2006204255A (ja) * 2005-01-31 2006-08-10 Canon Inc アセチル−CoAアシルトランスフェラーゼ遺伝子破壊ポリヒドロキシアルカノエート生産菌、またこれを利用したポリヒドロキシアルカノエート生産方法
US9297028B2 (en) * 2005-09-29 2016-03-29 Butamax Advanced Biofuels Llc Fermentive production of four carbon alcohols
EP3301182B1 (en) 2005-10-26 2020-03-18 Butamax (TM) Advanced Biofuels LLC Fermentative production of four carbon alcohols
US20100242345A1 (en) * 2006-05-19 2010-09-30 LS9, Inc Production of fatty acids & derivatives thereof
EP2094844A4 (en) 2006-12-15 2010-01-06 Biofuelchem Co Ltd IMPROVED BUTANOL PRODUCING MICROORGANISMS AND METHOD FOR THE PRODUCTION OF BUTANOL THEREWITH
WO2008130995A2 (en) * 2007-04-18 2008-10-30 E. I. Du Pont De Nemours And Company Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes
AU2009256209A1 (en) * 2008-06-04 2009-12-10 Butamax(Tm) Advanced Biofuels Llc Deletion mutants for the production of isobutanol
AU2010300722A1 (en) 2009-09-29 2012-04-12 Butamax(Tm) Advanced Biofuels Llc Improved flux to acetolactate-derived products in lactic acid bacteria
US9666620B2 (en) 2014-10-06 2017-05-30 Visera Technologies Company Limited Stacked filter and image sensor containing the same

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