PL3922301T3 - Szyki do dostarczania zmiennych pól elektrycznych do leczenia nowotworów (ttfields) z selektywnie adresowalnymi pod-elementami - Google Patents
Szyki do dostarczania zmiennych pól elektrycznych do leczenia nowotworów (ttfields) z selektywnie adresowalnymi pod-elementamiInfo
- Publication number
- PL3922301T3 PL3922301T3 PL21188977.9T PL21188977T PL3922301T3 PL 3922301 T3 PL3922301 T3 PL 3922301T3 PL 21188977 T PL21188977 T PL 21188977T PL 3922301 T3 PL3922301 T3 PL 3922301T3
- Authority
- PL
- Poland
- Prior art keywords
- ttfields
- arrays
- elements
- selectively addressable
- tumor treating
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0456—Specially adapted for transcutaneous electrical nerve stimulation [TENS]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0472—Structure-related aspects
- A61N1/0476—Array electrodes (including any electrode arrangement with more than one electrode for at least one of the polarities)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0526—Head electrodes
- A61N1/0529—Electrodes for brain stimulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/08—Arrangements or circuits for monitoring, protecting, controlling or indicating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36002—Cancer treatment, e.g. tumour
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/36025—External stimulators, e.g. with patch electrodes for treating a mental or cerebral condition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/3603—Control systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
- Biophysics (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Oncology (AREA)
- Child & Adolescent Psychology (AREA)
- Developmental Disabilities (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Social Psychology (AREA)
- Neurosurgery (AREA)
- Electrotherapy Devices (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862769319P | 2018-11-19 | 2018-11-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3922301T3 true PL3922301T3 (pl) | 2024-06-10 |
Family
ID=68699487
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL21188977.9T PL3922301T3 (pl) | 2018-11-19 | 2019-11-18 | Szyki do dostarczania zmiennych pól elektrycznych do leczenia nowotworów (ttfields) z selektywnie adresowalnymi pod-elementami |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US11395916B2 (pl) |
| EP (4) | EP3922300B1 (pl) |
| JP (2) | JP7451511B2 (pl) |
| KR (1) | KR102747887B1 (pl) |
| CN (2) | CN113015553B (pl) |
| CA (1) | CA3110448C (pl) |
| ES (1) | ES2976808T3 (pl) |
| HU (1) | HUE065574T2 (pl) |
| IL (1) | IL280843B2 (pl) |
| MX (2) | MX2021002624A (pl) |
| PL (1) | PL3922301T3 (pl) |
| WO (1) | WO2020104921A1 (pl) |
Families Citing this family (72)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10779875B2 (en) | 2013-05-06 | 2020-09-22 | Novocure Gmbh | Optimizing treatment using TTfields by changing the frequency during the course of long term tumor treatment |
| US10188851B2 (en) | 2015-10-28 | 2019-01-29 | Novocure Limited | TTField treatment with optimization of electrode positions on the head based on MRI-based conductivity measurements |
| US10821283B2 (en) | 2016-04-04 | 2020-11-03 | Novocure Gmbh | Reducing motility of cancer cells using tumor treating fields (TTFields) |
| EP4454697A3 (en) | 2016-06-30 | 2024-12-25 | Novocure GmbH | Arrays for longitudinal delivery of ttfields to a body |
| WO2018134733A1 (en) | 2017-01-19 | 2018-07-26 | Moshe Giladi | System for viewing cell cultures under a microscope whilst applying ttfields |
| US11986647B2 (en) | 2018-09-07 | 2024-05-21 | Novocure Gmbh | Treating autoinflammatory and mitochondrial diseases using an alternating electric field |
| DE112019004248T5 (de) * | 2018-10-12 | 2021-05-12 | Murata Manufacturing Co., Ltd. | Temperatursensorvorrichtung |
| PL3984590T3 (pl) | 2018-10-15 | 2023-05-02 | Novocure Gmbh | Wytwarzanie pól leczących guzy (pól elektrycznych do leczenia nowotworów ttfields) o wysokiej równomierności w całym mózgu |
| US11369790B2 (en) | 2018-10-25 | 2022-06-28 | Novocure Gmbh | Delivering alternating electric fields (e.g., TTFields) to a subject's spinal anatomy |
| PL3922301T3 (pl) | 2018-11-19 | 2024-06-10 | Novocure Gmbh | Szyki do dostarczania zmiennych pól elektrycznych do leczenia nowotworów (ttfields) z selektywnie adresowalnymi pod-elementami |
| CN118079235A (zh) | 2018-11-29 | 2024-05-28 | 诺沃库勒有限责任公司 | 用于递送TTField(肿瘤治疗场)的增强灵活性换能器阵列 |
| EP3974022B1 (en) | 2019-02-26 | 2024-04-17 | Novocure GmbH | Determining a frequency for ttfields treatment based on a physical parameter of targeted cancer cells |
| HUE069341T2 (hu) | 2019-02-27 | 2025-03-28 | Novocure Gmbh | Daganatkezelõ mezõk (TT-mezõk) bejuttatása implantálható átalakítótömbök használatával |
| DK3946322T3 (da) | 2019-03-29 | 2023-11-27 | Novocure Gmbh | Fremgangsmåder til genoprettelse af sensitivitet over for ttfields i ttfields-resistente kræftceller med ptger3-inhibitorer |
| ES2940749T3 (es) | 2019-04-17 | 2023-05-11 | Novocure Gmbh | Carga de datos desde un sistema aislado sin comprometer el aislamiento |
| CN121314073A (zh) | 2019-07-31 | 2026-01-13 | 诺沃库勒有限责任公司 | 经由埋入颅骨植入物中的电极施加肿瘤治疗场(TTField) |
| JP2022545344A (ja) | 2019-08-05 | 2022-10-27 | ノボキュア ゲーエムベーハー | Il11活性を阻害することによって、腫瘍治療電場(ttフィールド)に対するがん細胞の感受性を高める |
| EP4021559B1 (en) | 2019-08-30 | 2023-10-25 | Novocure GmbH | Delivering tumor treating fields (ttfields) to the neck |
| CN114786764B (zh) * | 2019-12-20 | 2026-01-02 | 诺沃库勒有限责任公司 | 用于向动物试验对象提供肿瘤治疗场的治疗组件 |
| DK4074367T3 (da) | 2019-12-31 | 2023-05-22 | Novocure Gmbh | Arrays til levering af tumorbehandlingsfelter (tt-felter) med individuelt tilgængelige elektrodeelementer og temperatursensorer |
| US12121739B2 (en) | 2019-12-31 | 2024-10-22 | Novocure Gmbh | Methods, systems, and apparatuses for managing temperatures induced by alternating fields |
| KR20220122679A (ko) | 2019-12-31 | 2022-09-02 | 노보큐어 게엠베하 | 채널들의 스위칭 및 진폭 조정 중 스파이크들을 방지하는 고전압, 고효율 사인파 생성기 |
| US20210299440A1 (en) | 2020-03-30 | 2021-09-30 | Novocure Gmbh | Intravenous / Intra-Spinal / Intra-Cavity / Intraventricular Delivery of TTFields (Tumor Treating Fields) for Treating Cancer and Metastases |
| EP4138988A1 (en) | 2020-04-24 | 2023-03-01 | Novocure Gmbh | Using alternating electric fields to increase permeability of the blood brain barrier |
| US11818943B2 (en) | 2020-06-25 | 2023-11-14 | Novocure Gmbh | Fabricating organic light emitting diodes (OLEDs) using tubulin |
| US12114991B2 (en) | 2020-09-25 | 2024-10-15 | Novocure Gmbh | Varying the metallization area on individual electrode elements in a tumor treating fields (TTFields) system to maximize current without overheating |
| KR20230074815A (ko) * | 2020-09-30 | 2023-05-31 | 노보큐어 게엠베하 | 탈거 가능한 어레이를 위한 커넥터 |
| US12194295B2 (en) * | 2020-09-30 | 2025-01-14 | Novocure Gmbh | Method and apparatus for delivering tumor treating fields to a torso, and method for determining locations for transducers to deliver tumor treating fields |
| EP4182009B1 (en) * | 2020-09-30 | 2025-02-19 | Novocure Gmbh | Connector for detachable array |
| WO2022130183A2 (en) * | 2020-12-17 | 2022-06-23 | Novocure Gmbh | Pyroelectric-based temperature sensing of transducer arrays for applying tumor treating fields (ttfields) |
| JP7820380B2 (ja) * | 2020-12-21 | 2026-02-25 | ノボキュア ゲーエムベーハー | 複合電極の最適化 |
| WO2022167939A1 (en) * | 2021-02-03 | 2022-08-11 | Novocure Gmbh | Varying parameters of tumor treating fields (ttfields) treatment to overcome treatment resistance |
| WO2022175803A1 (en) * | 2021-02-17 | 2022-08-25 | Novocure Gmbh | Arrays for delivering tumor treating fields (ttfields) with sets of electrode elements having individually adjustable active areas |
| WO2022190068A1 (en) | 2021-03-12 | 2022-09-15 | Novocure Gmbh | Methods of treating disease by skewing macrophage phenotype with alternating electric fields |
| WO2022201060A1 (en) | 2021-03-23 | 2022-09-29 | Novocure Gmbh | Method and apparatus for detecting and responding to changes in subjects |
| JP2024513769A (ja) | 2021-03-23 | 2024-03-27 | ノボキュア ゲーエムベーハー | 被験者の変化を検出し、それに応答するための方法および装置 |
| KR20230163379A (ko) | 2021-03-31 | 2023-11-30 | 노보큐어 게엠베하 | 종양 치료 필드(TTField) 시스템의 전극을 사용한 임피던스 단층 촬영 |
| MX2023015367A (es) * | 2021-06-22 | 2024-04-29 | Lifebridge Innovations Pbc | Aparato y método para mejorar la terapia de campo eléctrico para reducir tumores sólidos. |
| CA3224334A1 (en) * | 2021-06-30 | 2023-01-05 | Novocure Gmbh | System for delivering tumor treating fields (ttfields) and measuring impedance |
| MX2023014225A (es) * | 2021-06-30 | 2024-01-24 | Novocure Gmbh | Uso de condensadores para regular la corriente en matrices de transductores para aplicar campos de tratamiento de tumores (ttfields). |
| CA3224340A1 (en) * | 2021-06-30 | 2023-01-05 | Novocure Gmbh | Methods of treating cancer with alternating electric fields, checkpoint inhibitors, and combination chemotherapy |
| EP4344413B1 (en) * | 2021-07-21 | 2025-05-28 | Novocure GmbH | Conductive pad generating tumor treating field |
| CN113856052B (zh) * | 2021-09-28 | 2022-10-14 | 江苏海莱新创医疗科技有限公司 | 主动吸热型电极、肿瘤电场治疗系统及温度控制方法 |
| CN114099944A (zh) * | 2021-11-22 | 2022-03-01 | 杭州佑生医疗科技有限公司 | 外敷电极贴片和细胞分裂抑制装置 |
| WO2023116644A1 (zh) * | 2021-12-22 | 2023-06-29 | 江苏海莱新创医疗科技有限公司 | 肿瘤电场治疗系统及其交流电信号施加方法 |
| WO2023116670A1 (zh) * | 2021-12-22 | 2023-06-29 | 江苏海莱新创医疗科技有限公司 | 肿瘤电场治疗系统及其交流电信号施加方法 |
| CN114177527A (zh) * | 2021-12-24 | 2022-03-15 | 江苏海莱新创医疗科技有限公司 | 用于向受检者的身体施加电场的装置和系统 |
| US20250177765A1 (en) * | 2021-12-22 | 2025-06-05 | Jiangsu Healthy Life Innovation Medical Technology Co., Ltd | Tumor treating fields system and insulated electrode thereof |
| CN114288550A (zh) * | 2021-12-24 | 2022-04-08 | 江苏海莱新创医疗科技有限公司 | 用于向受检者的身体施加电场的装置、系统及其温度控制方法 |
| TW202333820A (zh) | 2021-12-29 | 2023-09-01 | 瑞士商諾沃庫勒有限責任公司 | 在使用交流電場治療受試者時藉由使用較大陰極和較小陽極來降低電知覺 |
| US12377280B2 (en) | 2021-12-30 | 2025-08-05 | Novocure Gmbh | Selecting values of parameters for treatment using tumor treating fields (TTFields) |
| CN114534091B (zh) * | 2022-02-17 | 2022-09-09 | 湖南安泰康成生物科技有限公司 | 利用电场抑制肿瘤增殖的设备及其控制装置 |
| US12478793B2 (en) | 2022-03-30 | 2025-11-25 | Novocure Gmbh | Reducing electrosensation whilst treating a subject using alternating electric fields by pairing transducer arrays together |
| IL314390A (en) * | 2022-03-30 | 2024-09-01 | Novocure Gmbh | Using interleaved cooling periods to increase the peak intensity of tumor treating fields |
| CN119947783A (zh) * | 2022-09-30 | 2025-05-06 | 诺沃库勒有限责任公司 | 通过去激活所选电极元件在使用交变电场治疗受试者时减小电感应 |
| WO2024076029A1 (ko) * | 2022-10-07 | 2024-04-11 | 주식회사 필드큐어 | 전극 어레이에서의 온도 측정 장치 |
| KR102853607B1 (ko) | 2022-10-25 | 2025-09-03 | 주식회사 필드큐어 | 전기장 전달 시스템 및 방법 |
| CN115920230A (zh) * | 2022-12-30 | 2023-04-07 | 江苏海莱新创医疗科技有限公司 | 电极片、电场治疗系统及控制方法 |
| CN115980490B (zh) * | 2022-12-30 | 2024-04-19 | 江苏海莱新创医疗科技有限公司 | 电极片的质量检测系统及方法、转接器、电场发生器 |
| CN115845260B (zh) * | 2022-12-30 | 2024-07-05 | 江苏海莱新创医疗科技有限公司 | 肿瘤电场治疗系统及其电极片、温度检测方法 |
| CN115671556A (zh) * | 2022-10-27 | 2023-02-03 | 江苏海莱新创医疗科技有限公司 | 肿瘤电场治疗系统及其电极片、肿瘤治疗设备 |
| KR20240072925A (ko) | 2022-11-17 | 2024-05-24 | 주식회사 필드큐어 | 임피던스 보상을 위한 전극 어레이 |
| JP2025539300A (ja) * | 2022-11-30 | 2025-12-05 | ノボキュア ゲーエムベーハー | 代替アレイ材料を有するトランスデューサアレイ |
| CN118477260B (zh) * | 2022-12-30 | 2025-11-11 | 江苏海莱新创医疗科技有限公司 | 电极片、肿瘤电场治疗系统及治疗设备 |
| CN117839069B (zh) * | 2022-12-30 | 2025-08-19 | 江苏海莱新创医疗科技有限公司 | 肿瘤电场治疗系统、肿瘤治疗设备及电极片温度检测方法 |
| US12268863B2 (en) | 2023-02-06 | 2025-04-08 | Novocure Gmbh | Shiftable transducer array with anisotropic material layer |
| EP4514447B1 (en) * | 2023-02-06 | 2025-06-04 | Novocure GmbH | Shiftable transducer array with anisotropic material layer |
| SE2350150A1 (en) * | 2023-02-15 | 2024-08-16 | Force Oncology Ab | Tumor treating fields (ttfields) equipment configurations for improved ease-of-use |
| KR20240129583A (ko) | 2023-02-20 | 2024-08-27 | 주식회사 필드큐어 | 대상체에 전기장을 전달하는 임베디드 전극 |
| CN116808435B (zh) * | 2023-04-21 | 2024-11-22 | 上海微场医疗科技有限公司 | 电场治疗设备、电子设备和可读存储介质 |
| WO2025068924A1 (en) | 2023-09-29 | 2025-04-03 | Novocure Gmbh | Using staggered changes in amplitude and frequency to ameliorate electrosensation during treatment with alternating electric fields |
| CN119951019A (zh) * | 2023-12-26 | 2025-05-09 | 杭州海莱新创医疗科技有限公司 | 一种交流电信号施加方法 |
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| JP7216829B2 (ja) | 2019-02-22 | 2023-02-01 | ノボキュア ゲーエムベーハー | Xelox又はfolfoxと組み合わせたttフィールドを用いる胃癌の治療 |
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| HUE069341T2 (hu) | 2019-02-27 | 2025-03-28 | Novocure Gmbh | Daganatkezelõ mezõk (TT-mezõk) bejuttatása implantálható átalakítótömbök használatával |
| DK3946322T3 (da) | 2019-03-29 | 2023-11-27 | Novocure Gmbh | Fremgangsmåder til genoprettelse af sensitivitet over for ttfields i ttfields-resistente kræftceller med ptger3-inhibitorer |
| US12369967B2 (en) | 2019-12-16 | 2025-07-29 | Lifebridge Innovations, Pbc | Apparatus and method for optimizing and adapting treatment of multiple tumors in patients with metastatic disease by electric field |
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2019
- 2019-11-18 PL PL21188977.9T patent/PL3922301T3/pl unknown
- 2019-11-18 HU HUE21188977A patent/HUE065574T2/hu unknown
- 2019-11-18 EP EP21188976.1A patent/EP3922300B1/en active Active
- 2019-11-18 JP JP2021520100A patent/JP7451511B2/ja active Active
- 2019-11-18 CN CN201980076291.3A patent/CN113015553B/zh active Active
- 2019-11-18 EP EP19809920.2A patent/EP3883642B1/en active Active
- 2019-11-18 EP EP22150741.1A patent/EP4019080B1/en active Active
- 2019-11-18 WO PCT/IB2019/059895 patent/WO2020104921A1/en not_active Ceased
- 2019-11-18 IL IL280843A patent/IL280843B2/en unknown
- 2019-11-18 MX MX2021002624A patent/MX2021002624A/es unknown
- 2019-11-18 CA CA3110448A patent/CA3110448C/en active Active
- 2019-11-18 KR KR1020217018534A patent/KR102747887B1/ko active Active
- 2019-11-18 ES ES21188977T patent/ES2976808T3/es active Active
- 2019-11-18 EP EP21188977.9A patent/EP3922301B1/en active Active
- 2019-11-18 US US16/686,918 patent/US11395916B2/en active Active
- 2019-11-18 CN CN202411889059.0A patent/CN119733171A/zh active Pending
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2021
- 2021-03-05 MX MX2024009505A patent/MX2024009505A/es unknown
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2022
- 2022-06-09 US US17/836,221 patent/US12029898B2/en active Active
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2024
- 2024-03-05 JP JP2024032958A patent/JP2024055977A/ja active Pending
- 2024-06-10 US US18/738,457 patent/US20240325739A1/en active Pending
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