PL3984590T3 - Wytwarzanie pól leczących guzy (pól elektrycznych do leczenia nowotworów ttfields) o wysokiej równomierności w całym mózgu - Google Patents

Wytwarzanie pól leczących guzy (pól elektrycznych do leczenia nowotworów ttfields) o wysokiej równomierności w całym mózgu

Info

Publication number
PL3984590T3
PL3984590T3 PL21205743.4T PL21205743T PL3984590T3 PL 3984590 T3 PL3984590 T3 PL 3984590T3 PL 21205743 T PL21205743 T PL 21205743T PL 3984590 T3 PL3984590 T3 PL 3984590T3
Authority
PL
Poland
Prior art keywords
ttfields
brain
high uniformity
uniformity throughout
tumor treating
Prior art date
Application number
PL21205743.4T
Other languages
English (en)
Inventor
Zeev Bomzon
Ariel NAEH
Ofir YESHARIM
Original Assignee
Novocure Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novocure Gmbh filed Critical Novocure Gmbh
Publication of PL3984590T3 publication Critical patent/PL3984590T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0456Specially adapted for transcutaneous electrical nerve stimulation [TENS]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0472Structure-related aspects
    • A61N1/0476Array electrodes (including any electrode arrangement with more than one electrode for at least one of the polarities)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0472Structure-related aspects
    • A61N1/0492Patch electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/08Arrangements or circuits for monitoring, protecting, controlling or indicating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36002Cancer treatment, e.g. tumour
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • A61N1/36025External stimulators, e.g. with patch electrodes for treating a mental or cerebral condition
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • A61N1/3603Control systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/40Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/40ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/63ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/50ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medical Informatics (AREA)
  • Epidemiology (AREA)
  • Primary Health Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Biophysics (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Databases & Information Systems (AREA)
  • Urology & Nephrology (AREA)
  • General Business, Economics & Management (AREA)
  • Pathology (AREA)
  • Business, Economics & Management (AREA)
  • Data Mining & Analysis (AREA)
  • Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Developmental Disabilities (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Social Psychology (AREA)
  • Electrotherapy Devices (AREA)
PL21205743.4T 2018-10-15 2019-10-11 Wytwarzanie pól leczących guzy (pól elektrycznych do leczenia nowotworów ttfields) o wysokiej równomierności w całym mózgu PL3984590T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862745689P 2018-10-15 2018-10-15

Publications (1)

Publication Number Publication Date
PL3984590T3 true PL3984590T3 (pl) 2023-05-02

Family

ID=68426548

Family Applications (1)

Application Number Title Priority Date Filing Date
PL21205743.4T PL3984590T3 (pl) 2018-10-15 2019-10-11 Wytwarzanie pól leczących guzy (pól elektrycznych do leczenia nowotworów ttfields) o wysokiej równomierności w całym mózgu

Country Status (7)

Country Link
US (4) US11154707B2 (pl)
EP (4) EP3984590B1 (pl)
JP (2) JP7284886B2 (pl)
CN (3) CN118925057A (pl)
HU (1) HUE061361T2 (pl)
PL (1) PL3984590T3 (pl)
WO (1) WO2020079554A1 (pl)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4454697A3 (en) 2016-06-30 2024-12-25 Novocure GmbH Arrays for longitudinal delivery of ttfields to a body
US11986647B2 (en) 2018-09-07 2024-05-21 Novocure Gmbh Treating autoinflammatory and mitochondrial diseases using an alternating electric field
PL3984590T3 (pl) 2018-10-15 2023-05-02 Novocure Gmbh Wytwarzanie pól leczących guzy (pól elektrycznych do leczenia nowotworów ttfields) o wysokiej równomierności w całym mózgu
US11369790B2 (en) 2018-10-25 2022-06-28 Novocure Gmbh Delivering alternating electric fields (e.g., TTFields) to a subject's spinal anatomy
WO2021111186A1 (en) 2019-12-02 2021-06-10 Novocure Gmbh Methods and apparatuses for optimizing transducer array placement
DK4074367T3 (da) 2019-12-31 2023-05-22 Novocure Gmbh Arrays til levering af tumorbehandlingsfelter (tt-felter) med individuelt tilgængelige elektrodeelementer og temperatursensorer
JP7677979B2 (ja) 2019-12-31 2025-05-15 ノボキュア ゲーエムベーハー 画像セグメンテーションのための方法、システム、および装置
KR20220122679A (ko) 2019-12-31 2022-09-02 노보큐어 게엠베하 채널들의 스위칭 및 진폭 조정 중 스파이크들을 방지하는 고전압, 고효율 사인파 생성기
EP4075442A1 (en) 2019-12-31 2022-10-19 Novocure GmbH Methods, systems, and apparatuses for fast approximation of electric field distribution
US20210299440A1 (en) 2020-03-30 2021-09-30 Novocure Gmbh Intravenous / Intra-Spinal / Intra-Cavity / Intraventricular Delivery of TTFields (Tumor Treating Fields) for Treating Cancer and Metastases
EP4138988A1 (en) 2020-04-24 2023-03-01 Novocure Gmbh Using alternating electric fields to increase permeability of the blood brain barrier
US11818943B2 (en) 2020-06-25 2023-11-14 Novocure Gmbh Fabricating organic light emitting diodes (OLEDs) using tubulin
US12114991B2 (en) 2020-09-25 2024-10-15 Novocure Gmbh Varying the metallization area on individual electrode elements in a tumor treating fields (TTFields) system to maximize current without overheating
US12194295B2 (en) * 2020-09-30 2025-01-14 Novocure Gmbh Method and apparatus for delivering tumor treating fields to a torso, and method for determining locations for transducers to deliver tumor treating fields
TWI830958B (zh) * 2020-10-16 2024-02-01 瑞士商諾沃庫勒有限責任公司 用於判定傳感器陣列在個體之身體上之最佳位置以及規劃電極元件集合在個體之身體上之定位的方法
US11869151B2 (en) * 2021-01-26 2024-01-09 Beth Israel Deaconess Medical Center Systems and methods for finite element analysis of tumor treating fields
WO2022175803A1 (en) * 2021-02-17 2022-08-25 Novocure Gmbh Arrays for delivering tumor treating fields (ttfields) with sets of electrode elements having individually adjustable active areas
WO2022190068A1 (en) 2021-03-12 2022-09-15 Novocure Gmbh Methods of treating disease by skewing macrophage phenotype with alternating electric fields
KR20230163379A (ko) 2021-03-31 2023-11-30 노보큐어 게엠베하 종양 치료 필드(TTField) 시스템의 전극을 사용한 임피던스 단층 촬영
MX2023014225A (es) 2021-06-30 2024-01-24 Novocure Gmbh Uso de condensadores para regular la corriente en matrices de transductores para aplicar campos de tratamiento de tumores (ttfields).
WO2023275822A1 (en) * 2021-06-30 2023-01-05 Novocure Gmbh Nonconductive field guide for resection cavity, and systems and methods of using same
US20230098801A1 (en) * 2021-09-30 2023-03-30 Novocure Gmbh Reducing Electrosensation Whilst Treating A Subject Using Alternating Electric Fields
JP2024543745A (ja) * 2021-12-14 2024-11-25 ノボキュア ゲーエムベーハー 被験者の身体の輪郭に合わせた形状を有するトランスデューサアレイ、およびトランスデューサアレイの形状および配置を決定する方法
TW202333820A (zh) 2021-12-29 2023-09-01 瑞士商諾沃庫勒有限責任公司 在使用交流電場治療受試者時藉由使用較大陰極和較小陽極來降低電知覺
US12377280B2 (en) 2021-12-30 2025-08-05 Novocure Gmbh Selecting values of parameters for treatment using tumor treating fields (TTFields)
IL314390A (en) 2022-03-30 2024-09-01 Novocure Gmbh Using interleaved cooling periods to increase the peak intensity of tumor treating fields
US12478793B2 (en) 2022-03-30 2025-11-25 Novocure Gmbh Reducing electrosensation whilst treating a subject using alternating electric fields by pairing transducer arrays together
EP4514447B1 (en) * 2023-02-06 2025-06-04 Novocure GmbH Shiftable transducer array with anisotropic material layer
US12268863B2 (en) 2023-02-06 2025-04-08 Novocure Gmbh Shiftable transducer array with anisotropic material layer
SE2350150A1 (en) * 2023-02-15 2024-08-16 Force Oncology Ab Tumor treating fields (ttfields) equipment configurations for improved ease-of-use
WO2025068924A1 (en) 2023-09-29 2025-04-03 Novocure Gmbh Using staggered changes in amplitude and frequency to ameliorate electrosensation during treatment with alternating electric fields

Family Cites Families (83)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6081744A (en) 1993-05-28 2000-06-27 Loos; Hendricus G. Electric fringe field generator for manipulating nervous systems
US6366813B1 (en) * 1998-08-05 2002-04-02 Dilorenzo Daniel J. Apparatus and method for closed-loop intracranical stimulation for optimal control of neurological disease
US8175698B2 (en) 2000-02-17 2012-05-08 Novocure Ltd. Treating bacteria with electric fields
US6868289B2 (en) 2002-10-02 2005-03-15 Standen Ltd. Apparatus for treating a tumor or the like and articles incorporating the apparatus for treatment of the tumor
US7146210B2 (en) 2000-02-17 2006-12-05 Standen Ltd. Apparatus and method for optimizing tumor treatment efficiency by electric fields
US7136699B2 (en) 2002-10-02 2006-11-14 Standen, Ltd. Apparatus for destroying dividing cells
US8447395B2 (en) 2000-02-17 2013-05-21 Novocure Ltd Treating bacteria with electric fields
US7089054B2 (en) 2002-10-02 2006-08-08 Standen Ltd. Apparatus and method for treating a tumor or the like
US7016725B2 (en) 2001-11-06 2006-03-21 Standen Ltd. Method and apparatus for destroying dividing cells
US7333852B2 (en) 2000-02-17 2008-02-19 Standen Ltd. Method and apparatus for destroying dividing cells
US7599746B2 (en) 2000-02-17 2009-10-06 Standen Ltd Apparatus and method for preventing the spread of cancerous metastases and for elimination of metastases
WO2002045791A2 (en) * 2000-10-26 2002-06-13 Medtronic, Inc. Method and apparatus for electrically stimulating the nervous system to improve ventricular dysfunction, heart failure, and other cardiac comditions
CN1976738B (zh) 2004-04-23 2010-09-01 诺沃库勒有限公司 使用不同频率的电场治疗肿瘤等
ES2663779T3 (es) 2004-12-07 2018-04-17 Novocure Limited Electrodos para aplicar un campo eléctrico in vivo durante un período de tiempo
CN102488967B (zh) 2004-12-27 2016-03-30 诺沃库勒有限公司 利用电场从不同方向治疗肿瘤等
US7917227B2 (en) 2005-10-03 2011-03-29 Standen Ltd. Optimizing characteristics of an electric field to increase the field's effect on proliferating cells
US10537728B2 (en) 2005-11-10 2020-01-21 ElectroCore, LLC Vagal nerve stimulation to avert or treat stroke or transient ischemic attack
US8019414B2 (en) 2006-04-05 2011-09-13 Novocure Ltd. Treating cancer using electromagnetic fields in combination with other treatment regimens
US7949403B2 (en) * 2007-02-27 2011-05-24 Accelerated Care Plus Corp. Electrical stimulation device and method for the treatment of neurological disorders
WO2009044289A1 (en) 2007-03-06 2009-04-09 Novocure Ltd. Treating cancer using electromagnetic fields in combination with photodynamic therapy
CN101820947A (zh) 2007-08-14 2010-09-01 诺沃库勒有限公司 用电场治疗寄生物
US8715203B2 (en) 2007-09-17 2014-05-06 Novocure Limited Composite electrode
WO2009155436A1 (en) * 2008-06-18 2009-12-23 Accelerated Care Plus Corp. Electrical stimulation method for reduction of joint compression
US8968173B2 (en) * 2008-07-16 2015-03-03 Frank Sivo Methods to arrest cancer cell growth and proliferation using electromagnetic energy delivered via electromagnetic coil systems
US20170164878A1 (en) * 2012-06-14 2017-06-15 Medibotics Llc Wearable Technology for Non-Invasive Glucose Monitoring
US9180302B2 (en) * 2012-08-31 2015-11-10 Greatbatch Ltd. Touch screen finger position indicator for a spinal cord stimulation programming device
CN108355242B (zh) * 2013-01-21 2022-04-15 卡拉健康公司 用于控制震颤的设备和方法
EP4049635A1 (en) * 2013-04-10 2022-08-31 ZOLL Circulation, Inc. Detecting and responding to preshivering
US9655669B2 (en) 2013-05-06 2017-05-23 Novocure Limited Optimizing treatment using TTFields by changing the frequency during the course of long term tumor treatment
US10779875B2 (en) 2013-05-06 2020-09-22 Novocure Gmbh Optimizing treatment using TTfields by changing the frequency during the course of long term tumor treatment
US20140371566A1 (en) * 2013-06-14 2014-12-18 Cardiothrive, Inc. Conforming patient contact interface and method for using same
US10293161B2 (en) * 2013-06-29 2019-05-21 Thync Global, Inc. Apparatuses and methods for transdermal electrical stimulation of nerves to modify or induce a cognitive state
US20150094557A1 (en) * 2013-09-30 2015-04-02 Mediatek Inc. Patches for bio-electrical signal processing
US9498635B2 (en) 2013-10-16 2016-11-22 Syntilla Medical LLC Implantable head located radiofrequency coupled neurostimulation system for head pain
JP6339194B2 (ja) * 2013-11-01 2018-06-06 ボストン サイエンティフィック ニューロモデュレイション コーポレイション 正中線で閾値以下治療を送出するためのシステム
US20150224318A1 (en) * 2014-02-12 2015-08-13 Pacesetter, Inc. Methods and systems for neurostimulation using paddle lead
KR102382416B1 (ko) * 2014-05-23 2022-04-01 일렉트로코어, 엘엘씨 미주 신경 자극 시스템 및 방법
KR20170063440A (ko) * 2014-05-25 2017-06-08 하이인 에쿼티 인베스트먼트 펀드 엘.피. 웨어러블 경피 신경자극기들
CN107949351A (zh) * 2015-03-30 2018-04-20 伊诺佩斯生物医药有限公司 用于血管内装置的天线
US9910453B2 (en) 2015-09-25 2018-03-06 Novocure Limited High voltage, high efficiency sine wave generator with pre-set frequency and adjustable amplitude
US10188851B2 (en) 2015-10-28 2019-01-29 Novocure Limited TTField treatment with optimization of electrode positions on the head based on MRI-based conductivity measurements
US9956405B2 (en) * 2015-12-18 2018-05-01 Thyne Global, Inc. Transdermal electrical stimulation at the neck to induce neuromodulation
US10821283B2 (en) 2016-04-04 2020-11-03 Novocure Gmbh Reducing motility of cancer cells using tumor treating fields (TTFields)
US10646708B2 (en) * 2016-05-20 2020-05-12 Thync Global, Inc. Transdermal electrical stimulation at the neck
EP4454697A3 (en) * 2016-06-30 2024-12-25 Novocure GmbH Arrays for longitudinal delivery of ttfields to a body
CA2972699A1 (en) 2016-07-10 2018-01-10 Novocure Limited Synchronizing tumor cells to the g2/m phase using ttfields combined with taxane or other anti-microtubule agents
KR102580614B1 (ko) 2016-08-18 2023-09-19 노보큐어 리미티드 종양치료장을 전달하기 위한 어레이들 내의 온도 측정
US11446487B2 (en) * 2016-09-23 2022-09-20 Beth Israel Deaconess Medical Center, Inc. System and methods for cancer treatment using alternating electric fields
US11109773B2 (en) 2016-12-13 2021-09-07 Novocure Gmbh Treating patients with TTFields with the electrode positions optimized using deformable templates
WO2018134733A1 (en) 2017-01-19 2018-07-26 Moshe Giladi System for viewing cell cultures under a microscope whilst applying ttfields
PL421532A1 (pl) * 2017-05-08 2018-11-19 Michalczyk Marta System do leczenia nowotworów wewnątrzczaszkowych z wykorzystaniem implantu, generującego ciągłe, zmienne pole elektryczne oraz ultradźwięki, zasilanego metodą przezskórnego transferu energii
WO2018217577A1 (en) * 2017-05-22 2018-11-29 Thync Global, Inc. Systems and methods for applying electrical energy to treat medical disorders
JP2021503360A (ja) 2017-11-17 2021-02-12 アッヴィ・インコーポレイテッド 膠芽腫の処置方法
US10953209B2 (en) 2018-03-28 2021-03-23 Board Of Regents Of The University Of Texas System Treating tumors using TTFields combined with a PARP inhibitor
EP3773726B1 (en) 2018-04-09 2024-06-05 Novocure GmbH Treating tumors with ttfields and an aurora kinase inhibitor
CA3096429C (en) 2018-04-10 2023-10-17 Zeev Bomzon Low frequency (<1 mhz) ac conductivity estimates derived from two mri images having different repetition times
IL279465B2 (en) 2018-07-03 2025-12-01 Edwin Chang Using alternating electric fields to increase cell membrane permeability
SG11202012564SA (en) 2018-07-10 2021-01-28 Novocure Gmbh Inhibiting viral infection using alternating electric fields
US11179322B2 (en) 2018-07-10 2021-11-23 Novocure Gmbh Methods and compositions for treating tumors with TTFields and sorafenib
KR102731369B1 (ko) 2018-07-18 2024-11-15 노보큐어 게엠베하 종양 치료장의 용량을 정량화하기 위한 전력 손실 밀도 및 관련 측정값의 사용
KR20250069692A (ko) 2018-08-23 2025-05-19 카스텐 하게만 뇌-혈액 장벽 투과성을 향상시키기 위한 교번 전기장의 이용
US11160977B2 (en) 2018-09-04 2021-11-02 Novocure Gmbh Delivering tumor treating fields (TTFields) to the infratentorial brain
US11986647B2 (en) 2018-09-07 2024-05-21 Novocure Gmbh Treating autoinflammatory and mitochondrial diseases using an alternating electric field
JP2022501098A (ja) 2018-09-07 2022-01-06 ノボキュア ゲーエムベーハー T細胞の増殖を低減する交流電場を使用する自己免疫性疾患の治療
US20200108031A1 (en) 2018-10-05 2020-04-09 Novocure Gmbh Treating Tumors Using TTFields Combined with ABT-751
PL3984590T3 (pl) * 2018-10-15 2023-05-02 Novocure Gmbh Wytwarzanie pól leczących guzy (pól elektrycznych do leczenia nowotworów ttfields) o wysokiej równomierności w całym mózgu
EP4458951A3 (en) 2018-10-23 2024-12-04 The Board of Trustees of the Leland Stanford Junior University Prevention and treatment of teratoma formation in stem cell-based thereapies using alternating electric fields
US11369790B2 (en) 2018-10-25 2022-06-28 Novocure Gmbh Delivering alternating electric fields (e.g., TTFields) to a subject's spinal anatomy
US20200146586A1 (en) 2018-11-14 2020-05-14 Novocure Gmbh Creating Accurate Computational Head Models of Patients Using Datasets Combining MRI and CT Images
PL3922301T3 (pl) 2018-11-19 2024-06-10 Novocure Gmbh Szyki do dostarczania zmiennych pól elektrycznych do leczenia nowotworów (ttfields) z selektywnie adresowalnymi pod-elementami
JP7246486B2 (ja) 2019-01-08 2023-03-27 ノボキュア ゲーエムベーハー 腫瘍治療電場(ttfields)を使用した治療を計画するための異なるタイプの組織への画像のセグメンテーションの品質評価
DK3946322T3 (da) 2019-03-29 2023-11-27 Novocure Gmbh Fremgangsmåder til genoprettelse af sensitivitet over for ttfields i ttfields-resistente kræftceller med ptger3-inhibitorer
ES2940749T3 (es) 2019-04-17 2023-05-11 Novocure Gmbh Carga de datos desde un sistema aislado sin comprometer el aislamiento
USD934892S1 (en) 2019-05-03 2021-11-02 Novocure Gmbh Display screen or portion thereof with a graphical user interface
CN121314073A (zh) 2019-07-31 2026-01-13 诺沃库勒有限责任公司 经由埋入颅骨植入物中的电极施加肿瘤治疗场(TTField)
JP2022545344A (ja) 2019-08-05 2022-10-27 ノボキュア ゲーエムベーハー Il11活性を阻害することによって、腫瘍治療電場(ttフィールド)に対するがん細胞の感受性を高める
EP4021559B1 (en) 2019-08-30 2023-10-25 Novocure GmbH Delivering tumor treating fields (ttfields) to the neck
CN114340667A (zh) 2019-09-10 2022-04-12 诺沃库勒有限责任公司 通过向癌细胞施加交变电场和给予检查点抑制剂来降低癌细胞生存能力的方法
JP7687698B2 (ja) 2019-12-26 2025-06-03 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 癌細胞における異常な解糖的代謝を正常化する方法
DK4074367T3 (da) 2019-12-31 2023-05-22 Novocure Gmbh Arrays til levering af tumorbehandlingsfelter (tt-felter) med individuelt tilgængelige elektrodeelementer og temperatursensorer
KR20220122679A (ko) 2019-12-31 2022-09-02 노보큐어 게엠베하 채널들의 스위칭 및 진폭 조정 중 스파이크들을 방지하는 고전압, 고효율 사인파 생성기
US20210299440A1 (en) 2020-03-30 2021-09-30 Novocure Gmbh Intravenous / Intra-Spinal / Intra-Cavity / Intraventricular Delivery of TTFields (Tumor Treating Fields) for Treating Cancer and Metastases
EP4138988A1 (en) 2020-04-24 2023-03-01 Novocure Gmbh Using alternating electric fields to increase permeability of the blood brain barrier

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