PL3930838T3 - Pochodne n-(pirydynylo)acetamidu jako inhibitory hat p300/cbp oraz sposoby ich zastosowania - Google Patents
Pochodne n-(pirydynylo)acetamidu jako inhibitory hat p300/cbp oraz sposoby ich zastosowaniaInfo
- Publication number
- PL3930838T3 PL3930838T3 PL20714389.2T PL20714389T PL3930838T3 PL 3930838 T3 PL3930838 T3 PL 3930838T3 PL 20714389 T PL20714389 T PL 20714389T PL 3930838 T3 PL3930838 T3 PL 3930838T3
- Authority
- PL
- Poland
- Prior art keywords
- pyridinyl
- methods
- acetamide derivatives
- cbp hat
- hat inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962811143P | 2019-02-27 | 2019-02-27 | |
| US201962879852P | 2019-07-29 | 2019-07-29 | |
| PCT/US2020/019786 WO2020176558A1 (en) | 2019-02-27 | 2020-02-26 | P300/cbp hat inhibitors and methods for their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3930838T3 true PL3930838T3 (pl) | 2024-12-02 |
Family
ID=70005771
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL20714389.2T PL3930838T3 (pl) | 2019-02-27 | 2020-02-26 | Pochodne n-(pirydynylo)acetamidu jako inhibitory hat p300/cbp oraz sposoby ich zastosowania |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20220135538A1 (pl) |
| EP (1) | EP3930838B1 (pl) |
| JP (1) | JP7638880B2 (pl) |
| CN (1) | CN113727756B (pl) |
| AU (1) | AU2020227742A1 (pl) |
| CA (1) | CA3131383A1 (pl) |
| DK (1) | DK3930838T3 (pl) |
| ES (1) | ES2989353T3 (pl) |
| FI (1) | FI3930838T3 (pl) |
| HR (1) | HRP20241237T1 (pl) |
| HU (1) | HUE068415T2 (pl) |
| LT (1) | LT3930838T (pl) |
| PL (1) | PL3930838T3 (pl) |
| PT (1) | PT3930838T (pl) |
| RS (1) | RS65998B1 (pl) |
| SI (1) | SI3930838T1 (pl) |
| SM (1) | SMT202400386T1 (pl) |
| TW (1) | TWI850342B (pl) |
| WO (1) | WO2020176558A1 (pl) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20240122941A1 (en) * | 2020-12-25 | 2024-04-18 | National Cancer Center | Therapy based on synthetic lethality in swi/snf complex-dysfunction cancer |
| WO2025169375A1 (ja) | 2024-02-07 | 2025-08-14 | 住友ファーマ株式会社 | 4員環構造で置換された3級アミド誘導体 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112014014767A2 (pt) | 2011-12-16 | 2017-06-13 | Olema Pharmaceuticals Inc | novos compostos de benzopirano, composições e usos dos mesmos |
| US20160235716A1 (en) | 2014-09-18 | 2016-08-18 | Abbvie Inc. | Spirocyclic hat inhibitors and methods for their use |
| CN107108512B (zh) | 2014-10-10 | 2021-05-04 | 基因泰克公司 | 治疗性化合物及其用途 |
| EP3632915A1 (en) * | 2014-11-27 | 2020-04-08 | Genentech, Inc. | 4,5,6,7-tetrahydro-1 h-pyrazolo[4,3-c]pyridin-3-amine compounds as cbp and/or ep300 inhibitors |
| EP3302468A4 (en) * | 2015-06-01 | 2019-02-06 | The Scripps Research Institute | SMALL MOLECULAR ANALOGS OF NEMO BINDING PEPTIDE |
| WO2017205536A2 (en) * | 2016-05-24 | 2017-11-30 | Genentech, Inc. | Therapeutic compounds and uses thereof |
| MA45146A (fr) * | 2016-05-24 | 2021-03-24 | Constellation Pharmaceuticals Inc | Dérivés de pyrazolopyridine pour le traitement du cancer |
| EP3643703A4 (en) | 2017-06-21 | 2020-12-23 | Daiichi Sankyo Co., Ltd. | EP300 / CREBBP INHIBITOR |
| UY37866A (es) * | 2017-09-07 | 2019-03-29 | Glaxosmithkline Ip Dev Ltd | Nuevos compuestos derivados de benzoimidazol sustituidos que reducen la proteína myc (c-myc) en las células e inhiben la histona acetiltransferasa de p300/cbp. |
| AU2019220662B2 (en) * | 2018-02-16 | 2024-06-13 | Constellation Pharmaceuticals, Inc. | P300/CBP HAT inhibitors |
-
2020
- 2020-02-26 HR HRP20241237TT patent/HRP20241237T1/hr unknown
- 2020-02-26 CA CA3131383A patent/CA3131383A1/en active Pending
- 2020-02-26 EP EP20714389.2A patent/EP3930838B1/en active Active
- 2020-02-26 WO PCT/US2020/019786 patent/WO2020176558A1/en not_active Ceased
- 2020-02-26 JP JP2021550155A patent/JP7638880B2/ja active Active
- 2020-02-26 RS RS20241084A patent/RS65998B1/sr unknown
- 2020-02-26 SM SM20240386T patent/SMT202400386T1/it unknown
- 2020-02-26 US US17/434,102 patent/US20220135538A1/en not_active Abandoned
- 2020-02-26 TW TW109106273A patent/TWI850342B/zh active
- 2020-02-26 FI FIEP20714389.2T patent/FI3930838T3/fi active
- 2020-02-26 HU HUE20714389A patent/HUE068415T2/hu unknown
- 2020-02-26 ES ES20714389T patent/ES2989353T3/es active Active
- 2020-02-26 PL PL20714389.2T patent/PL3930838T3/pl unknown
- 2020-02-26 AU AU2020227742A patent/AU2020227742A1/en not_active Abandoned
- 2020-02-26 CN CN202080031338.7A patent/CN113727756B/zh active Active
- 2020-02-26 DK DK20714389.2T patent/DK3930838T3/da active
- 2020-02-26 PT PT207143892T patent/PT3930838T/pt unknown
- 2020-02-26 SI SI202030496T patent/SI3930838T1/sl unknown
- 2020-02-26 LT LTEPPCT/US2020/019786T patent/LT3930838T/lt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT3930838T (pt) | 2024-10-04 |
| JP2022522349A (ja) | 2022-04-18 |
| FI3930838T3 (fi) | 2024-10-14 |
| EP3930838A1 (en) | 2022-01-05 |
| HUE068415T2 (hu) | 2024-12-28 |
| LT3930838T (lt) | 2024-09-10 |
| CN113727756A (zh) | 2021-11-30 |
| JP7638880B2 (ja) | 2025-03-04 |
| DK3930838T3 (da) | 2024-10-07 |
| SMT202400386T1 (it) | 2024-11-15 |
| US20220135538A1 (en) | 2022-05-05 |
| EP3930838B1 (en) | 2024-07-10 |
| WO2020176558A1 (en) | 2020-09-03 |
| CA3131383A1 (en) | 2020-09-03 |
| TW202045492A (zh) | 2020-12-16 |
| CN113727756B (zh) | 2024-07-02 |
| HRP20241237T1 (hr) | 2024-12-06 |
| TWI850342B (zh) | 2024-08-01 |
| AU2020227742A1 (en) | 2021-09-16 |
| SI3930838T1 (sl) | 2024-10-30 |
| RS65998B1 (sr) | 2024-10-31 |
| ES2989353T3 (es) | 2024-11-26 |
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