PL398193A1 - Halogenopochodne benzo[b]furanów, ewentualnie w postaci farmaceutycznie dopuszczalnej soli oraz zastosowanie halogenopochodnych benzo[b]furanów - Google Patents

Halogenopochodne benzo[b]furanów, ewentualnie w postaci farmaceutycznie dopuszczalnej soli oraz zastosowanie halogenopochodnych benzo[b]furanów

Info

Publication number
PL398193A1
PL398193A1 PL398193A PL39819312A PL398193A1 PL 398193 A1 PL398193 A1 PL 398193A1 PL 398193 A PL398193 A PL 398193A PL 39819312 A PL39819312 A PL 39819312A PL 398193 A1 PL398193 A1 PL 398193A1
Authority
PL
Poland
Prior art keywords
furans
benzo
pharmaceutically acceptable
halogenated benzo
acceptable salt
Prior art date
Application number
PL398193A
Other languages
English (en)
Other versions
PL223225B1 (pl
Inventor
Mariola Krawiecka
Bożena Kuran
Jerzy Kossakowski
Marcin Cieślak
Julia Kaźmierczak-Barańska
Karolina Królewska
Barbara Nawrot
Original Assignee
Centrum Badan Molekularnych I Makromolekularnych Polskiej Akademii Nauk
Warszawski Uniwersytet Medyczny
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centrum Badan Molekularnych I Makromolekularnych Polskiej Akademii Nauk, Warszawski Uniwersytet Medyczny filed Critical Centrum Badan Molekularnych I Makromolekularnych Polskiej Akademii Nauk
Priority to PL398193A priority Critical patent/PL223225B1/pl
Priority to EP13150611.5A priority patent/EP2631232B1/en
Publication of PL398193A1 publication Critical patent/PL398193A1/pl
Publication of PL223225B1 publication Critical patent/PL223225B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Przedmiotem zgłoszenia są halogenopochodne benzo[b]furanów przedstawione wzorem (1a) i (1d) oraz zastosowanie halogenopochodnych bezo[b]furanów objętych wspólnym wzorem (1), ewentualnie w postaci farmaceutycznie dopuszczalnych soli, do wytwarzania leków przeciwnowotworowych i/lub leków antyproliferacyjnych, działających selektywnie na nowotwory typu białaczek i komórki zawiesinowe.
PL398193A 2012-02-21 2012-02-21 Halogenopochodne benzo[b]furanów, ewentualnie w postaci farmaceutycznie dopuszczalnej soli oraz zastosowanie halogenopochodnych benzo[b]furanów PL223225B1 (pl)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PL398193A PL223225B1 (pl) 2012-02-21 2012-02-21 Halogenopochodne benzo[b]furanów, ewentualnie w postaci farmaceutycznie dopuszczalnej soli oraz zastosowanie halogenopochodnych benzo[b]furanów
EP13150611.5A EP2631232B1 (en) 2012-02-21 2013-01-09 Halogen derivatives of benzo[b]furans useful as anti-neoplastic or anti-proliferative drugs

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL398193A PL223225B1 (pl) 2012-02-21 2012-02-21 Halogenopochodne benzo[b]furanów, ewentualnie w postaci farmaceutycznie dopuszczalnej soli oraz zastosowanie halogenopochodnych benzo[b]furanów

Publications (2)

Publication Number Publication Date
PL398193A1 true PL398193A1 (pl) 2013-09-02
PL223225B1 PL223225B1 (pl) 2016-10-31

Family

ID=47501024

Family Applications (1)

Application Number Title Priority Date Filing Date
PL398193A PL223225B1 (pl) 2012-02-21 2012-02-21 Halogenopochodne benzo[b]furanów, ewentualnie w postaci farmaceutycznie dopuszczalnej soli oraz zastosowanie halogenopochodnych benzo[b]furanów

Country Status (2)

Country Link
EP (1) EP2631232B1 (pl)
PL (1) PL223225B1 (pl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111423374B (zh) * 2020-05-18 2023-03-21 合肥工业大学 一种二氢吡唑磺酰胺类化合物及其制备方法和用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2131020B1 (es) 1997-10-13 2000-03-01 Lacer Sa Derivados de benzofurano, dihidrobenzofunaro, dihidrobenzopirano y benzopirano como agentes antidepresivos.
WO2004108709A1 (en) * 2003-06-05 2004-12-16 Warner-Lambert Company Llc Tetrazol benzofurancarboxamides with p13k aktivity as therapeutic agents
GB0907551D0 (en) * 2009-05-01 2009-06-10 Univ Dundee Treatment or prophylaxis of proliferative conditions

Also Published As

Publication number Publication date
EP2631232A1 (en) 2013-08-28
EP2631232B1 (en) 2015-09-16
PL223225B1 (pl) 2016-10-31

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