PL400947A1 - Sposób wytwarzania 17a-oxa-D-homo-androst-1,4-dien-3,17-dionu - Google Patents

Sposób wytwarzania 17a-oxa-D-homo-androst-1,4-dien-3,17-dionu

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Publication number
PL400947A1
PL400947A1 PL400947A PL40094712A PL400947A1 PL 400947 A1 PL400947 A1 PL 400947A1 PL 400947 A PL400947 A PL 400947A PL 40094712 A PL40094712 A PL 40094712A PL 400947 A1 PL400947 A1 PL 400947A1
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PL
Poland
Prior art keywords
androst
oxa
dione
homo
diene
Prior art date
Application number
PL400947A
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English (en)
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PL218587B1 (pl
Inventor
Anna Panek
Teresa Kołek
Alina Świzdor
Natalia Milecka-Tronina
Original Assignee
Uniwersytet Przyrodniczy We Wroclawiu
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Application filed by Uniwersytet Przyrodniczy We Wroclawiu filed Critical Uniwersytet Przyrodniczy We Wroclawiu
Priority to PL400947A priority Critical patent/PL218587B1/pl
Publication of PL400947A1 publication Critical patent/PL400947A1/pl
Publication of PL218587B1 publication Critical patent/PL218587B1/pl

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Wynalazek dotyczy sposobu wytwarzania 17a-oxa-D-homo-androst-1,4-dien-3,17-dionu, o wzorze 2, na drodze mikrobiologicznej hydrolizy estru, utlenieniu powstalego alkoholu do ketonu, a nastepnie utlenianiu typu Baeyera-Villigera do ?-laktonu w pierscieniu D, z wykorzystaniem systemu enzymatycznego szczepu Penicillium lilacinum AM111, w którym jako substrat stosuje sie propionian 1-dehydrotestosteronu, o wzorze 1. Sposobem, wedlug wynalazku, mozna otrzymac zwiazek, który ze wzgledu na swoja aktywnosc biologiczna, jest stosowany w przemysle farmaceutycznym.
PL400947A 2012-09-27 2012-09-27 Sposób wytwarzania 17a-oxa-D-homo-androst-1,4-dien-3,17-dionu PL218587B1 (pl)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL400947A PL218587B1 (pl) 2012-09-27 2012-09-27 Sposób wytwarzania 17a-oxa-D-homo-androst-1,4-dien-3,17-dionu

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL400947A PL218587B1 (pl) 2012-09-27 2012-09-27 Sposób wytwarzania 17a-oxa-D-homo-androst-1,4-dien-3,17-dionu

Publications (2)

Publication Number Publication Date
PL400947A1 true PL400947A1 (pl) 2013-05-27
PL218587B1 PL218587B1 (pl) 2015-01-30

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PL400947A PL218587B1 (pl) 2012-09-27 2012-09-27 Sposób wytwarzania 17a-oxa-D-homo-androst-1,4-dien-3,17-dionu

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PL (1) PL218587B1 (pl)

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Publication number Publication date
PL218587B1 (pl) 2015-01-30

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Effective date: 20140714