PL4037679T3 - Sposób wytwarzania walsartanu o wysokiej czystości - Google Patents

Sposób wytwarzania walsartanu o wysokiej czystości

Info

Publication number
PL4037679T3
PL4037679T3 PL20896548.3T PL20896548T PL4037679T3 PL 4037679 T3 PL4037679 T3 PL 4037679T3 PL 20896548 T PL20896548 T PL 20896548T PL 4037679 T3 PL4037679 T3 PL 4037679T3
Authority
PL
Poland
Prior art keywords
producing high
valsartan
purity
purity valsartan
producing
Prior art date
Application number
PL20896548.3T
Other languages
English (en)
Inventor
Nitin Sharadchandra Pradhan
Vijay Trimbak KADAM
Vishalkumar Rajendrakumar SHAH
Pankaj Shrawan CHAUDHARI
Harpreet Singh Minhas
Gurpreet Singh Minhas
Original Assignee
Harman Finochem Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harman Finochem Limited filed Critical Harman Finochem Limited
Publication of PL4037679T3 publication Critical patent/PL4037679T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N2030/022—Column chromatography characterised by the kind of separation mechanism
    • G01N2030/027—Liquid chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL20896548.3T 2019-12-02 2020-11-28 Sposób wytwarzania walsartanu o wysokiej czystości PL4037679T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN201921049418 2019-12-02
PCT/IN2020/050990 WO2021111464A1 (en) 2019-12-02 2020-11-28 A process for the preparation of highly pure valsartan

Publications (1)

Publication Number Publication Date
PL4037679T3 true PL4037679T3 (pl) 2026-03-09

Family

ID=76221532

Family Applications (1)

Application Number Title Priority Date Filing Date
PL20896548.3T PL4037679T3 (pl) 2019-12-02 2020-11-28 Sposób wytwarzania walsartanu o wysokiej czystości

Country Status (6)

Country Link
US (1) US12365654B2 (pl)
EP (1) EP4037679B1 (pl)
CN (1) CN114845713B (pl)
ES (1) ES3048170T3 (pl)
PL (1) PL4037679T3 (pl)
WO (1) WO2021111464A1 (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4422615A4 (en) * 2021-10-28 2025-09-17 Texas A & M Univ Sys COMPOSITIONS OF STABLE METFORMIN AND SIMILAR DRUG PRODUCTS WITH CONTROL OF NITROSO IMPURITIES
WO2023205787A1 (en) * 2022-04-22 2023-10-26 Mork Benjamin V Compositions and methods for remediation using dithionite and activated carbons

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE134624T1 (de) 1990-02-19 1996-03-15 Ciba Geigy Ag Acylverbindungen
US5260325A (en) 1991-08-19 1993-11-09 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking tertiary amides
US5488141A (en) * 1994-06-10 1996-01-30 Rohm And Haas Company Removal of carbonyl impurities from αβ unsaturated carboxylic acid esters
WO1997030036A1 (en) 1996-02-15 1997-08-21 Novartis Ag Aryl derivatives
IT1292437B1 (it) 1997-06-30 1999-02-08 Zambon Spa Processo di orto-metallazione utile per la sintesi di 1 - tetrazol- 5-il) benzeni 2-sostituiti
IT1301759B1 (it) 1998-06-19 2000-07-07 Nicox Sa Sali nitrati di farmaci antiipertensivi
AU2001267404A1 (en) 2000-05-04 2001-11-12 Ipf Pharmaceuticals Gmbh Novel compounds for the treatment of inflammatory and cardiovascular diseases
DK1313714T3 (da) * 2000-07-19 2008-12-15 Novartis Ag Valsartansalte
WO2009001375A2 (en) * 2007-06-27 2008-12-31 Matrix Laboratories Ltd Improved process for preparing pure valsartan
US10077251B2 (en) * 2012-10-29 2018-09-18 Biophore India Pharmaceuticals Pvt. Ltd. Process for the synthesis of Dabigatran Etexilate and its intermediates
WO2018040065A1 (zh) * 2016-09-02 2018-03-08 诺瑞特国际药业股份有限公司 缬沙坦二钠盐的晶型
ES3043832T3 (en) * 2018-07-13 2025-11-25 Zhejiang Huahai Pharm Co Ltd Method for synthesizing valsartan
CN109761924B (zh) * 2019-02-26 2020-09-01 安徽美诺华药物化学有限公司 一种改进的缬沙坦反应混合液的后处理方法

Also Published As

Publication number Publication date
US20230057675A1 (en) 2023-02-23
WO2021111464A1 (en) 2021-06-10
CN114845713A (zh) 2022-08-02
US12365654B2 (en) 2025-07-22
EP4037679A4 (en) 2023-11-08
CN114845713B (zh) 2025-07-08
EP4037679A1 (en) 2022-08-10
ES3048170T3 (en) 2025-12-09
EP4037679B1 (en) 2025-08-06

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