PL407635A1 - Trans-5-ethyl-4- (4'-methylphenyl) dihydrofuran-2-one and the method of its preparation - Google Patents
Trans-5-ethyl-4- (4'-methylphenyl) dihydrofuran-2-one and the method of its preparationInfo
- Publication number
- PL407635A1 PL407635A1 PL407635A PL40763514A PL407635A1 PL 407635 A1 PL407635 A1 PL 407635A1 PL 407635 A PL407635 A PL 407635A PL 40763514 A PL40763514 A PL 40763514A PL 407635 A1 PL407635 A1 PL 407635A1
- Authority
- PL
- Poland
- Prior art keywords
- dihydrofuran
- methylphenyl
- ethyl
- trans
- preparation
- Prior art date
Links
- MRWZBZVJKHDYOB-RYUDHWBXSA-N (4S,5S)-5-ethyl-4-(4-methylphenyl)oxolan-2-one Chemical compound CC[C@@H]1OC(=O)C[C@H]1c1ccc(C)cc1 MRWZBZVJKHDYOB-RYUDHWBXSA-N 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- DOVIIDOBRCRNFK-PAJVWHMTSA-N IC(C)[C@H]1[C@@H](CC(O1)=O)C1=CC=C(C=C1)C Chemical compound IC(C)[C@H]1[C@@H](CC(O1)=O)C1=CC=C(C=C1)C DOVIIDOBRCRNFK-PAJVWHMTSA-N 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 238000004440 column chromatography Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 230000001717 pathogenic effect Effects 0.000 abstract 1
- DBGVGMSCBYYSLD-UHFFFAOYSA-N tributylstannane Chemical compound CCCC[SnH](CCCC)CCCC DBGVGMSCBYYSLD-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Furan Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Wynalazek dotyczy racemicznego trans-5-etylo-4-(4'-metylofenylo)-dihydrofuran-2-onu o wzorze 1 oraz sposobu jego otrzymywania, który polega na tym, że trans-5-(1-jodoetylo)-4-(4'-metylofenylo)-dihydrofuran-2-on poddaje się reakcji z wodorkiem tri-n-butylocyny(IV) w rozpuszczalniku organicznym, a następnie powstały w wyniku reakcji trans-5-etylo-4-(4'-metylofenylo)-dihydrofuran-2-on wydziela się w postaci czystej metodą chromatografii kolumnowej. Racemiczny ß-arylo-?-etylo-?-lakton o wzorze 1 może znaleźć zastosowanie w przemyśle rolno-spożywczym jako związek ograniczający rozwój patogennych szczepów bakterii.The invention relates to racemic trans-5-ethyl-4- (4'-methylphenyl) dihydrofuran-2-one of formula 1 and a method for its preparation, which consists in that trans-5- (1-iodoethyl) -4- ( 4'-methylphenyl) dihydrofuran-2-one is reacted with tri-n-butyltin (IV) hydride in an organic solvent, followed by the reaction of trans-5-ethyl-4- (4'-methylphenyl) dihydrofuran -2-one is isolated in pure form by column chromatography. The racemic ß-aryl-α-ethyl-α-lactone of formula 1 may find application in the agri-food industry as a compound limiting the development of pathogenic bacterial strains.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL407635A PL221653B1 (en) | 2014-03-24 | 2014-03-24 | Trans-5-ethyl-4- (4'-methylphenyl) dihydrofuran-2-one and the method of its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL407635A PL221653B1 (en) | 2014-03-24 | 2014-03-24 | Trans-5-ethyl-4- (4'-methylphenyl) dihydrofuran-2-one and the method of its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL407635A1 true PL407635A1 (en) | 2015-01-19 |
| PL221653B1 PL221653B1 (en) | 2016-05-31 |
Family
ID=52305626
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL407635A PL221653B1 (en) | 2014-03-24 | 2014-03-24 | Trans-5-ethyl-4- (4'-methylphenyl) dihydrofuran-2-one and the method of its preparation |
Country Status (1)
| Country | Link |
|---|---|
| PL (1) | PL221653B1 (en) |
-
2014
- 2014-03-24 PL PL407635A patent/PL221653B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL221653B1 (en) | 2016-05-31 |
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