PL407950A1 - Sposób uzyskiwania białka poliepitopowego oraz wektor DNA do realizacji tego sposobu - Google Patents

Sposób uzyskiwania białka poliepitopowego oraz wektor DNA do realizacji tego sposobu

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Publication number
PL407950A1
PL407950A1 PL407950A PL40795014A PL407950A1 PL 407950 A1 PL407950 A1 PL 407950A1 PL 407950 A PL407950 A PL 407950A PL 40795014 A PL40795014 A PL 40795014A PL 407950 A1 PL407950 A1 PL 407950A1
Authority
PL
Poland
Prior art keywords
obtaining
dna vector
execution
polyepitope protein
protein
Prior art date
Application number
PL407950A
Other languages
English (en)
Other versions
PL228341B1 (pl
Inventor
Piotr Skowron
Agnieszka Żylicz-Stachula
Olga Żołnierkiewicz
Małgorzata Skowron
Łukasz Janus
Joanna Jeżewska-Frąckowiak
Aneta Szymańska
Original Assignee
Bio Ventures Institute Spółka Z Ograniczoną Odpowiedzialnością
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Ventures Institute Spółka Z Ograniczoną Odpowiedzialnością filed Critical Bio Ventures Institute Spółka Z Ograniczoną Odpowiedzialnością
Priority to PL407950A priority Critical patent/PL228341B1/pl
Priority to US15/305,453 priority patent/US10874735B2/en
Priority to LTEP15738474.4T priority patent/LT3134426T/lt
Priority to RS20210076A priority patent/RS61384B1/sr
Priority to SM20210045T priority patent/SMT202100045T1/it
Priority to PCT/IB2015/052915 priority patent/WO2015162560A1/en
Priority to SI201531495T priority patent/SI3134426T1/sl
Priority to ES15738474T priority patent/ES2842216T3/es
Priority to DK15738474.4T priority patent/DK3134426T3/da
Priority to JP2017507091A priority patent/JP6692796B2/ja
Priority to CN201580028495.1A priority patent/CN106488983A/zh
Priority to EP15738474.4A priority patent/EP3134426B1/en
Priority to PT157384744T priority patent/PT3134426T/pt
Priority to PL15738474T priority patent/PL3134426T3/pl
Publication of PL407950A1 publication Critical patent/PL407950A1/pl
Priority to IL248011A priority patent/IL248011B/en
Publication of PL228341B1 publication Critical patent/PL228341B1/pl
Priority to US17/132,103 priority patent/US20210187102A1/en

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    • C—CHEMISTRY; METALLURGY
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    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/29—Hepatitis virus
    • A61K39/292—Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/66—General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligation; Use of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/64—Medicinal preparations containing antigens or antibodies characterised by the architecture of the carrier-antigen complex, e.g. repetition of carrier-antigen units
    • A61K2039/645—Dendrimers; Multiple antigen peptides
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    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
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    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10151—Methods of production or purification of viral material
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    • C12N2800/00—Nucleic acids vectors
    • C12N2800/80—Vectors containing sites for inducing double-stranded breaks, e.g. meganuclease restriction sites

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Ujawniono sposób uzyskiwania białka poliepitopowego oraz wektor DNA do realizacji tego sposobu. Uzyskiwane zgodnie z wynalazkiem białka mogą znaleźć szereg zastosowań, w szczególności być wykorzystane do wytwarzania ulepszonych szczepionek.
PL407950A 2014-04-21 2014-04-21 Sposób uzyskiwania białka poliepitopowego oraz wektor DNA do realizacji tego sposobu PL228341B1 (pl)

Priority Applications (16)

Application Number Priority Date Filing Date Title
PL407950A PL228341B1 (pl) 2014-04-21 2014-04-21 Sposób uzyskiwania białka poliepitopowego oraz wektor DNA do realizacji tego sposobu
ES15738474T ES2842216T3 (es) 2014-04-21 2015-04-21 Procedimiento para obtener una proteína poliepitópica, así como un vector de ADN para realizar este procedimiento
CN201580028495.1A CN106488983A (zh) 2014-04-21 2015-04-21 获得多表位蛋白的方法以及用于体现该方法的dna载体
RS20210076A RS61384B1 (sr) 2014-04-21 2015-04-21 Postupak dobijanja proteina sa više epitopa kao i vektora dnk za izvođenje ovog postupka
SM20210045T SMT202100045T1 (it) 2014-04-21 2015-04-21 Metodo per ottenere una proteina poliepitopica nonche' un vettore di dna per l'attuazione di questo metodo
PCT/IB2015/052915 WO2015162560A1 (en) 2014-04-21 2015-04-21 A method of obtaining a polyepitopic protein as well as a dna vector for embodying this method
SI201531495T SI3134426T1 (sl) 2014-04-21 2015-04-21 Postopek za pridobivanje poliepitopnega proteina in DNA vektor za ta postopek
US15/305,453 US10874735B2 (en) 2014-04-21 2015-04-21 Method of obtaining a polyepitopic protein and polyepitopic DNA vector
DK15738474.4T DK3134426T3 (da) 2014-04-21 2015-04-21 Fremgangsmåde til at opnå et polyepitopisk protein samt en DNA-vektor til at udføre denne fremgangsmåde
JP2017507091A JP6692796B2 (ja) 2014-04-21 2015-04-21 ポリエピトープタンパク質を得る方法とこの方法を具体化するためのｄｎａベクター
LTEP15738474.4T LT3134426T (lt) 2014-04-21 2015-04-21 Poliepitopinio baltymo gavimo būdas, o taip pat dnr vektorius, skirtas šio metodo įgyvendinimui
EP15738474.4A EP3134426B1 (en) 2014-04-21 2015-04-21 A method of obtaining a polyepitopic protein as well as a dna vector for embodying this method
PT157384744T PT3134426T (pt) 2014-04-21 2015-04-21 Um método para obter uma proteína poliepitópica, assim como um vetor de adn para incorporar este método
PL15738474T PL3134426T3 (pl) 2014-04-21 2015-04-21 Sposób uzyskiwania białka poliepitopowego oraz wektor DNA do realizacji tego sposobu
IL248011A IL248011B (en) 2014-04-21 2016-09-25 A method for producing a polyepitope protein as well as a DNA vector embodying this method
US17/132,103 US20210187102A1 (en) 2014-04-21 2020-12-23 Method of obtaining a polyepitopic protein and polyepitopic dna vector

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL407950A PL228341B1 (pl) 2014-04-21 2014-04-21 Sposób uzyskiwania białka poliepitopowego oraz wektor DNA do realizacji tego sposobu

Publications (2)

Publication Number Publication Date
PL407950A1 true PL407950A1 (pl) 2015-10-26
PL228341B1 PL228341B1 (pl) 2018-03-30

Family

ID=53610926

Family Applications (2)

Application Number Title Priority Date Filing Date
PL407950A PL228341B1 (pl) 2014-04-21 2014-04-21 Sposób uzyskiwania białka poliepitopowego oraz wektor DNA do realizacji tego sposobu
PL15738474T PL3134426T3 (pl) 2014-04-21 2015-04-21 Sposób uzyskiwania białka poliepitopowego oraz wektor DNA do realizacji tego sposobu

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL15738474T PL3134426T3 (pl) 2014-04-21 2015-04-21 Sposób uzyskiwania białka poliepitopowego oraz wektor DNA do realizacji tego sposobu

Country Status (14)

Country Link
US (2) US10874735B2 (pl)
EP (1) EP3134426B1 (pl)
JP (1) JP6692796B2 (pl)
CN (1) CN106488983A (pl)
DK (1) DK3134426T3 (pl)
ES (1) ES2842216T3 (pl)
IL (1) IL248011B (pl)
LT (1) LT3134426T (pl)
PL (2) PL228341B1 (pl)
PT (1) PT3134426T (pl)
RS (1) RS61384B1 (pl)
SI (1) SI3134426T1 (pl)
SM (1) SMT202100045T1 (pl)
WO (1) WO2015162560A1 (pl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3549947B1 (en) 2018-04-04 2024-05-08 Uniwersytet Gdanski Polyrgd peptides obtained by chemical and biotechnology methods with injury reducing and/or neuroprotective effects and a kit for their activity evaluation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0916733A1 (de) * 1997-11-17 1999-05-19 Roche Diagnostics GmbH Verfahren und Kit zur Klonierung von Fragmenten
US20030074695A1 (en) * 1998-06-24 2003-04-17 Farese Robert V. Plant diacylglycerol O-acyltransferase and uses thereof
FR2950350B1 (fr) * 2009-09-24 2013-12-13 Centre Nat Rech Scient Nouveaux polynucleotides et polypeptides chimeriques permettant la secretion d'un polypeptide d'interet en association avec des exosomes et leurs utilisations
US9221882B2 (en) * 2010-05-21 2015-12-29 Technische Universitat Munchen Biosynthetic proline/alanine random coil polypeptides and their uses

Also Published As

Publication number Publication date
RS61384B1 (sr) 2021-02-26
CN106488983A (zh) 2017-03-08
DK3134426T3 (da) 2021-01-25
SI3134426T1 (sl) 2021-03-31
SMT202100045T1 (it) 2021-03-15
US20170095553A1 (en) 2017-04-06
EP3134426B1 (en) 2020-10-28
WO2015162560A1 (en) 2015-10-29
PL3134426T3 (pl) 2021-06-14
JP6692796B2 (ja) 2020-05-13
LT3134426T (lt) 2021-02-10
ES2842216T3 (es) 2021-07-13
EP3134426A1 (en) 2017-03-01
US20210187102A1 (en) 2021-06-24
US10874735B2 (en) 2020-12-29
IL248011B (en) 2021-06-30
JP2017513527A (ja) 2017-06-01
PT3134426T (pt) 2021-01-29
PL228341B1 (pl) 2018-03-30
IL248011A0 (en) 2016-11-30

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