PL407993A1 - Method for producing R-(-)-2-chloro-1-(4'-fluorophenyl)-ethan-1-ol - Google Patents

Method for producing R-(-)-2-chloro-1-(4'-fluorophenyl)-ethan-1-ol

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Publication number
PL407993A1
PL407993A1 PL407993A PL40799314A PL407993A1 PL 407993 A1 PL407993 A1 PL 407993A1 PL 407993 A PL407993 A PL 407993A PL 40799314 A PL40799314 A PL 40799314A PL 407993 A1 PL407993 A1 PL 407993A1
Authority
PL
Poland
Prior art keywords
fluorophenyl
chloro
producing
ethan
formula
Prior art date
Application number
PL407993A
Other languages
Polish (pl)
Other versions
PL222141B1 (en
Inventor
Tomasz Janeczko
Edyta Kostrzewa-Susłow
Original Assignee
Uniwersytet Przyrodniczy we Wrocławiu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniwersytet Przyrodniczy we Wrocławiu filed Critical Uniwersytet Przyrodniczy we Wrocławiu
Priority to PL407993A priority Critical patent/PL222141B1/en
Publication of PL407993A1 publication Critical patent/PL407993A1/en
Publication of PL222141B1 publication Critical patent/PL222141B1/en

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Wynalazek dotyczy sposobu wytwarzania R-(-)-2-chloro-1-(4'-fluorofenylo)-etan-1-olu, o wzorze 2. W wyniku działania układu enzymatycznego zawartego w komórkach szczepu Rhodotorula rubra KCh 82, następuje enancjoselektywna redukcja grupy karbonylowej substratu o wzorze 1. Uzyskany w ten sposób alkohol wydziela się z wodnej kultury mikroorganizmu, znanym sposobem, przez ekstrakcję rozpuszczalnikiem organicznym niemieszającym się z wodą.The invention relates to a method for producing R - (-) - 2-chloro-1- (4'-fluorophenyl) -ethane-1-ol, formula 2. As a result of the enzymatic system contained in the cells of the strain Rhodotorula rubra KCh 82, enantioselective reduction occurs of the carbonyl group of the substrate of formula 1. The alcohol thus obtained is isolated from the aqueous culture of the microorganism in a known manner by extraction with a water-immiscible organic solvent.

PL407993A 2014-04-24 2014-04-24 Method for producing R-(-)-2-chloro-1-(4'-fluorophenyl)-ethan-1-ol PL222141B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL407993A PL222141B1 (en) 2014-04-24 2014-04-24 Method for producing R-(-)-2-chloro-1-(4'-fluorophenyl)-ethan-1-ol

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL407993A PL222141B1 (en) 2014-04-24 2014-04-24 Method for producing R-(-)-2-chloro-1-(4'-fluorophenyl)-ethan-1-ol

Publications (2)

Publication Number Publication Date
PL407993A1 true PL407993A1 (en) 2015-03-30
PL222141B1 PL222141B1 (en) 2016-07-29

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ID=52727697

Family Applications (1)

Application Number Title Priority Date Filing Date
PL407993A PL222141B1 (en) 2014-04-24 2014-04-24 Method for producing R-(-)-2-chloro-1-(4'-fluorophenyl)-ethan-1-ol

Country Status (1)

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PL (1) PL222141B1 (en)

Also Published As

Publication number Publication date
PL222141B1 (en) 2016-07-29

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