PL407988A1 - Method for producing R-(-)-2-bromo-1-(2'-methoxyphenylo)-ethan-1-ol - Google Patents
Method for producing R-(-)-2-bromo-1-(2'-methoxyphenylo)-ethan-1-olInfo
- Publication number
- PL407988A1 PL407988A1 PL407988A PL40798814A PL407988A1 PL 407988 A1 PL407988 A1 PL 407988A1 PL 407988 A PL407988 A PL 407988A PL 40798814 A PL40798814 A PL 40798814A PL 407988 A1 PL407988 A1 PL 407988A1
- Authority
- PL
- Poland
- Prior art keywords
- ethan
- bromo
- producing
- methoxyphenylo
- formula
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- FROJNSZKFGHHNR-QMMMGPOBSA-N (1r)-2-bromo-1-(2-methoxyphenyl)ethanol Chemical compound COC1=CC=CC=C1[C@@H](O)CBr FROJNSZKFGHHNR-QMMMGPOBSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 241000223254 Rhodotorula mucilaginosa Species 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 230000002255 enzymatic effect Effects 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Wynalazek dotyczy sposobu wytwarzania R-(-)-2-bromo-1-(2'-metoksyfenylo)-etan-1-olu, o wzorze 2. W wyniku działania układu enzymatycznego zawartego w komórkach szczepu Rhodotorula rubra KCh 82, następuje enancjoselektywna redukcja grupy karbonylowej substratu o wzorze 1. Uzyskany w ten sposób alkohol wydziela się z wodnej kultury mikroorganizmu, znanym sposobem, przez ekstrakcję rozpuszczalnikiem organicznym niemieszającym się z wodą.The invention relates to a method for producing R - (-) - 2-bromo-1- (2'-methoxyphenyl) -ethan-1-ol, formula 2. As a result of the enzymatic system contained in the cells of the strain Rhodotorula rubra KCh 82, enantioselective reduction occurs of the carbonyl group of the substrate of formula 1. The alcohol thus obtained is isolated from the aqueous culture of the microorganism in a known manner by extraction with a water-immiscible organic solvent.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL407988A PL228397B1 (en) | 2014-04-24 | 2014-04-24 | Method for producing R-(-)-2-bromo-1-(2'-methoxyphenylo)-ethan-1-ol |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL407988A PL228397B1 (en) | 2014-04-24 | 2014-04-24 | Method for producing R-(-)-2-bromo-1-(2'-methoxyphenylo)-ethan-1-ol |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL407988A1 true PL407988A1 (en) | 2015-05-25 |
| PL228397B1 PL228397B1 (en) | 2018-03-30 |
Family
ID=53176123
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL407988A PL228397B1 (en) | 2014-04-24 | 2014-04-24 | Method for producing R-(-)-2-bromo-1-(2'-methoxyphenylo)-ethan-1-ol |
Country Status (1)
| Country | Link |
|---|---|
| PL (1) | PL228397B1 (en) |
-
2014
- 2014-04-24 PL PL407988A patent/PL228397B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL228397B1 (en) | 2018-03-30 |
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