PL413951A1 - Method for producing optically pure (+)-(R)-7-hydroxyflavanone - Google Patents

Method for producing optically pure (+)-(R)-7-hydroxyflavanone

Info

Publication number
PL413951A1
PL413951A1 PL413951A PL41395115A PL413951A1 PL 413951 A1 PL413951 A1 PL 413951A1 PL 413951 A PL413951 A PL 413951A PL 41395115 A PL41395115 A PL 41395115A PL 413951 A1 PL413951 A1 PL 413951A1
Authority
PL
Poland
Prior art keywords
hydroxyflavanone
optically pure
hours
organic solvent
water
Prior art date
Application number
PL413951A
Other languages
Polish (pl)
Other versions
PL233420B1 (en
Inventor
Edyta Kostrzewa-Susłow
Monika Dymarska
Tomasz Janeczko
Original Assignee
Uniwersytet Przyrodniczy we Wrocławiu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniwersytet Przyrodniczy we Wrocławiu filed Critical Uniwersytet Przyrodniczy we Wrocławiu
Priority to PL41395115A priority Critical patent/PL233420B1/en
Publication of PL413951A1 publication Critical patent/PL413951A1/en
Publication of PL233420B1 publication Critical patent/PL233420B1/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Sposób wytwarzania (+)-(R)-7-hydroksyflawanonu o wzorze 2, polega na tym, że do podłoża odpowiedniego dla grzybów strzępkowych wprowadza się szczep Aspergillus niger SBJ, następnie po upływie co najmniej 48 godzin do hodowli wprowadza się substrat, którym jest (±)-octan 7-hydroksyflawanonu o wzorze 1, rozpuszczony w rozpuszczalniku organicznym mieszającym się z wodą, transformację prowadzi się przy ciągłym wstrząsaniu, co najwyżej 30 godzin, po czym produkt ekstrahuje się rozpuszczalnikiem organicznym niemieszającym się z wodą i oczyszcza chromatograficznie. Związek ten może znaleźć zastosowanie jako antyoksydant w przemyśle spożywczym oraz jako składnik preparatów farmaceutycznych i kosmetycznych.The method of producing (+) - (R) -7-hydroxyflavanone of the formula II consists in the introduction of Aspergillus niger SBJ strain into a medium suitable for filamentous fungi, then after at least 48 hours the substrate which is 7-hydroxyflavanone (±) -acetate 1, dissolved in a water-miscible organic solvent, transformation is carried out with continuous shaking, at most 30 hours, after which the product is extracted with a water-immiscible organic solvent and purified by chromatography. This compound can be used as an antioxidant in the food industry and as an ingredient in pharmaceutical and cosmetic preparations.

PL41395115A 2015-09-14 2015-09-14 Method for producing optically pure (+)-(R)-7-hydroxyflavanone PL233420B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL41395115A PL233420B1 (en) 2015-09-14 2015-09-14 Method for producing optically pure (+)-(R)-7-hydroxyflavanone

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL41395115A PL233420B1 (en) 2015-09-14 2015-09-14 Method for producing optically pure (+)-(R)-7-hydroxyflavanone

Publications (2)

Publication Number Publication Date
PL413951A1 true PL413951A1 (en) 2017-03-27
PL233420B1 PL233420B1 (en) 2019-10-31

Family

ID=58360215

Family Applications (1)

Application Number Title Priority Date Filing Date
PL41395115A PL233420B1 (en) 2015-09-14 2015-09-14 Method for producing optically pure (+)-(R)-7-hydroxyflavanone

Country Status (1)

Country Link
PL (1) PL233420B1 (en)

Also Published As

Publication number Publication date
PL233420B1 (en) 2019-10-31

Similar Documents

Publication Publication Date Title
EP4666856A3 (en) Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto
TN2016000268A1 (en) N-azaspirocycloalkane substituted n-heteroaryl compounds and compositions for inhibiting the activity of shp2.
MX383856B (en) COMPOUNDS AND COMPOSITIONS FOR INHIBITING SHP2 ACTIVITY.
SG11201900868XA (en) Ido1 inhibitor and preparation method and application thereof
MX2017006136A (en) Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto.
AU2015205268A1 (en) Pyridylaminoacetic acid compound and polyoxyethylene castor oil-containing pharmaceutical composition
EA201890821A1 (en) NEW IMIDAZO DERIVATIVES [4,5-b] Pyridine as DYRK1 / CLK1 DUAL INHIBITORS
MX2018002332A (en) Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto.
MX2018002331A (en) Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto.
EA201691934A1 (en) SUBSTITUTED 4,5,6,7-TETRAHYDRO-PYRAZOLO [1,5-ALPHA] PYRIMIDINE DERIVATIVES AND 2,3-DIHYDRO-1H-IMIDAZO [1,2-BETA] PYRASOL DERIVATIVES AS AN INHIBITORS ROS1
MX2018010801A (en) a-TRUXILLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF.
WO2018092042A3 (en) Solvent and method for extracting active compounds from plants and use of the solvent
CA3035115C (en) Nitrogenous heterocyclic aromatic compound, preparation method therefor, pharmaceutical composition thereof, and application thereof
SG11201907019TA (en) Hair treatment method
PL417788A1 (en) 8-O-β-D-4"-methoxyglucopyranosyl-6-methylflavone and method for producing 8-O-β-D-4"-methoxyglucopyranosyl-6-methylflavone
PL413949A1 (en) Method for producing optically pure (+)-(R)-7-hydroxyflavanone
PL413945A1 (en) Method for producing optically pure (+)-(R)-7-hydroxyflavanone
PL413955A1 (en) Method for producing optically pure (+)-(R)-7-hydroxyflavanone
PL413948A1 (en) Method for producing optically pure (+)-(R)-7-hydroxyflavanone
PL413947A1 (en) Method for producing optically pure (+)-(R)-7-hydroxyflavanone
PL413946A1 (en) Method for producing optically pure (+)-(R)-7-hydroxyflavanone
PL413939A1 (en) Method for producing optically pure (+)-(R)-7-hydroxyflavanone
PL413953A1 (en) Method for producing optically pure (+)-(R)-7-hydroxyflavanone
PL413950A1 (en) Method for producing optically pure (+)-(R)-7-hydroxyflavanone
PL417881A1 (en) Method for producing optically clean (+)-(R)-7-hydroxyflavanone