PL4176901T3 - Stabilne kompozycje heksapeptydu foxy-5 o wysokiej rozpuszczalności zawierające zasadę azotową - Google Patents

Stabilne kompozycje heksapeptydu foxy-5 o wysokiej rozpuszczalności zawierające zasadę azotową

Info

Publication number
PL4176901T3
PL4176901T3 PL21213698.0T PL21213698T PL4176901T3 PL 4176901 T3 PL4176901 T3 PL 4176901T3 PL 21213698 T PL21213698 T PL 21213698T PL 4176901 T3 PL4176901 T3 PL 4176901T3
Authority
PL
Poland
Prior art keywords
foxy
hexapeptide
high solubility
nitrogen base
stable compositions
Prior art date
Application number
PL21213698.0T
Other languages
English (en)
Inventor
Dennis Henriksen
Original Assignee
Wntresearch Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wntresearch Ab filed Critical Wntresearch Ab
Publication of PL4176901T3 publication Critical patent/PL4176901T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
PL21213698.0T 2021-12-10 2021-12-10 Stabilne kompozycje heksapeptydu foxy-5 o wysokiej rozpuszczalności zawierające zasadę azotową PL4176901T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP21213698.0A EP4176901B1 (en) 2021-12-10 2021-12-10 Stable compositions of foxy-5 hexapeptide with high solubility comprising a nitrogen base

Publications (1)

Publication Number Publication Date
PL4176901T3 true PL4176901T3 (pl) 2024-04-08

Family

ID=78829785

Family Applications (1)

Application Number Title Priority Date Filing Date
PL21213698.0T PL4176901T3 (pl) 2021-12-10 2021-12-10 Stabilne kompozycje heksapeptydu foxy-5 o wysokiej rozpuszczalności zawierające zasadę azotową

Country Status (10)

Country Link
US (1) US20250325485A1 (pl)
EP (2) EP4176901B1 (pl)
JP (1) JP2024545142A (pl)
KR (1) KR20240119292A (pl)
CN (1) CN118613275A (pl)
AU (1) AU2022403638A1 (pl)
CA (1) CA3242341A1 (pl)
ES (1) ES2969155T3 (pl)
PL (1) PL4176901T3 (pl)
WO (1) WO2023104952A1 (pl)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1888628T3 (da) 2005-05-30 2015-02-02 Wntres Ab En peptidligand til forstyrrelse af cancercellemigration
AU2019254478A1 (en) * 2018-04-16 2020-12-03 Merck Patent Gmbh Method for stabilizing protein comprising formulations by using a meglumine salt.
EP3613757A1 (en) 2018-08-20 2020-02-26 Wntresearch AB Solution phase routes for wnt hexapeptides
EP3666789A1 (en) 2018-12-14 2020-06-17 Wntresearch AB Linear solution phase routes for wnt hexapeptides

Also Published As

Publication number Publication date
JP2024545142A (ja) 2024-12-05
CN118613275A (zh) 2024-09-06
EP4444353A1 (en) 2024-10-16
EP4176901B1 (en) 2023-10-04
KR20240119292A (ko) 2024-08-06
CA3242341A1 (en) 2023-06-15
US20250325485A1 (en) 2025-10-23
AU2022403638A1 (en) 2024-07-11
EP4176901A1 (en) 2023-05-10
ES2969155T3 (es) 2024-05-16
WO2023104952A1 (en) 2023-06-15
EP4176901C0 (en) 2023-10-04

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