PL4192839T3 - Związki pośrednie remdesiwiru - Google Patents
Związki pośrednie remdesiwiruInfo
- Publication number
- PL4192839T3 PL4192839T3 PL21756058.0T PL21756058T PL4192839T3 PL 4192839 T3 PL4192839 T3 PL 4192839T3 PL 21756058 T PL21756058 T PL 21756058T PL 4192839 T3 PL4192839 T3 PL 4192839T3
- Authority
- PL
- Poland
- Prior art keywords
- remdesivir
- intermediates
- remdesivir intermediates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/18—Acyclic radicals, substituted by carbocyclic rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HUP2000258 | 2020-08-06 | ||
| HUP2000371 | 2020-11-10 | ||
| PCT/IB2021/057242 WO2022029704A1 (en) | 2020-08-06 | 2021-08-06 | Remdesivir intermediates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL4192839T3 true PL4192839T3 (pl) | 2026-02-16 |
Family
ID=89662465
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL21756058.0T PL4192839T3 (pl) | 2020-08-06 | 2021-08-06 | Związki pośrednie remdesiwiru |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP4192839B1 (pl) |
| CA (1) | CA3185450A1 (pl) |
| LT (1) | LT4192839T (pl) |
| PL (1) | PL4192839T3 (pl) |
| RS (1) | RS67481B1 (pl) |
| WO (1) | WO2022029704A1 (pl) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114641299A (zh) | 2020-01-27 | 2022-06-17 | 吉利德科学公司 | 用于治疗SARS CoV-2感染的方法 |
| CA3169340A1 (en) | 2020-03-12 | 2021-09-16 | Pavel R. Badalov | Methods of preparing 1'-cyano nucleosides |
| EP4132651B1 (en) | 2020-04-06 | 2026-03-18 | Gilead Sciences, Inc. | Inhalation formulations of 1'-cyano substituted carbanucleoside analogs |
| ES3041698T3 (en) | 2020-05-29 | 2025-11-13 | Gilead Sciences Inc | Remdesivir for the treatment of viral infections |
| US11939347B2 (en) | 2020-06-24 | 2024-03-26 | Gilead Sciences, Inc. | 1′-cyano nucleoside analogs and uses thereof |
| DK4204421T3 (da) | 2020-08-27 | 2024-05-27 | Gilead Sciences Inc | Forbindelser og fremgangsmåder til behandling af virale infektioner |
| MX2024010591A (es) | 2022-03-02 | 2024-09-06 | Gilead Sciences Inc | Compuestos y metodos para el tratamiento de infecciones virales. |
| CN115521316B (zh) * | 2022-09-23 | 2024-07-26 | 深圳安泰维生物医药有限公司 | 一种核苷类化合物或其中间体的制备方法和核苷类化合物的中间体 |
| US12357577B1 (en) | 2024-02-02 | 2025-07-15 | Gilead Sciences, Inc. | Pharmaceutical formulations and uses thereof |
| CN116554176A (zh) * | 2023-05-11 | 2023-08-08 | 南京正济医药研究有限公司 | 一种核苷类化合物的制备方法 |
| CN121347707B (zh) * | 2025-12-19 | 2026-03-20 | 湖南尚成生物科技有限公司 | 瑞德西韦中间体gs-441524的高效液相色谱检测方法 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5116687B2 (ja) | 2005-11-02 | 2013-01-09 | バイエル・ファルマ・アクチェンゲゼルシャフト | がんおよび他の過剰増殖性疾患の処置のためのピロロ［２，１−ｆ］［１，２，４］トリアジン−４−イルアミンＩＧＦ−１Ｒキナーゼ阻害剤 |
| RS54008B1 (sr) | 2008-04-23 | 2015-10-30 | Gilead Sciences Inc. | 1`-supstituisani karba-nukleozidni analozi za antivirusnu terapiju |
| CR20170278A (es) | 2010-07-22 | 2017-09-29 | Gilead Sciences Inc | Métodos y compuestos para tratar infecciones virales por paramyxoviridae |
| UA119050C2 (uk) | 2013-11-11 | 2019-04-25 | Ґілеад Саєнсиз, Інк. | ПІРОЛО[1.2-f][1.2.4]ТРИАЗИНИ, ЯКІ ВИКОРИСТОВУЮТЬСЯ ДЛЯ ЛІКУВАННЯ РЕСПІРАТОРНО-СИНЦИТІАЛЬНИХ ВІРУСНИХ ІНФЕКЦІЙ |
| TWI767201B (zh) | 2014-10-29 | 2022-06-11 | 美商基利科學股份有限公司 | 絲狀病毒科病毒感染之治療 |
| CN110330540A (zh) | 2019-08-08 | 2019-10-15 | 木天(济南)生物科技有限公司 | 核苷盐及其制备方法 |
| CN110776512A (zh) | 2019-11-28 | 2020-02-11 | 成都傲飞生物化学品有限责任公司 | 一种核苷类似物的制备方法 |
| CN111205327B (zh) | 2020-02-17 | 2022-05-31 | 南京法恩化学有限公司 | 一种瑞德西韦的制备方法 |
| CN111205294B (zh) | 2020-02-27 | 2021-10-01 | 江苏阿尔法药业股份有限公司 | 一种瑞德西韦中间体的制备方法 |
| CN111171078B (zh) | 2020-02-27 | 2022-04-22 | 江苏阿尔法药业股份有限公司 | 一种瑞德西韦的合成方法 |
| CN111187269A (zh) | 2020-02-27 | 2020-05-22 | 江苏阿尔法药业有限公司 | 一种瑞德西韦中间体的合成方法 |
| CN111233930B (zh) | 2020-03-04 | 2022-05-13 | 江苏阿尔法药业股份有限公司 | 一种瑞德西韦的制备方法 |
| CN111116656A (zh) | 2020-03-04 | 2020-05-08 | 江苏福瑞康泰药业有限公司 | 一种瑞德西韦的制备方法 |
| CN111269263A (zh) | 2020-03-09 | 2020-06-12 | 上海龙翔生物医药开发有限公司 | 一种瑞德西韦侧链中间体及其制备方法 |
| CN111233870A (zh) | 2020-03-11 | 2020-06-05 | 中国科学技术大学 | 用于快速制备瑞德西韦药物中间体的方法 |
| CN111233869B (zh) | 2020-03-12 | 2022-09-16 | 杭州新博思生物医药有限公司 | 用于制备瑞德西韦关键中间体的新化合物及其制备方法 |
| CN111393478B (zh) | 2020-03-13 | 2023-05-26 | 深圳市宝安区新材料研究院 | 一种瑞德西韦的合成方法 |
| CN111233931B (zh) | 2020-03-26 | 2022-03-22 | 宿迁盛基医药科技有限公司 | 一种瑞德西韦的合成方法 |
| CN111471070B (zh) | 2020-04-26 | 2022-05-13 | 江苏阿尔法药业股份有限公司 | 瑞德西韦的合成方法 |
| CN111440176B (zh) | 2020-04-28 | 2022-04-26 | 江苏大学 | 金属配合物促进的瑞德西韦中间体的合成方法 |
| CN111393392A (zh) | 2020-05-07 | 2020-07-10 | 河南省科学院高新技术研究中心 | 瑞德西韦关键中间体2,3,5-三苄氧基-d-核糖酸-1,4-内酯的合成 |
| CN111620876B (zh) | 2020-05-07 | 2021-09-28 | 普济生物科技（台州）有限公司 | 瑞德西韦关键中间体的合成方法 |
| CN111620903A (zh) | 2020-06-17 | 2020-09-04 | 安徽贝克联合制药有限公司 | C-核苷类似物以及用于合成瑞德西韦合成的含腈c-核苷类化合物的制备方法及其应用 |
-
2021
- 2021-08-06 PL PL21756058.0T patent/PL4192839T3/pl unknown
- 2021-08-06 LT LTEPPCT/IB2021/057242T patent/LT4192839T/lt unknown
- 2021-08-06 RS RS20251231A patent/RS67481B1/sr unknown
- 2021-08-06 WO PCT/IB2021/057242 patent/WO2022029704A1/en not_active Ceased
- 2021-08-06 EP EP21756058.0A patent/EP4192839B1/en active Active
- 2021-08-06 CA CA3185450A patent/CA3185450A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA3185450A1 (en) | 2022-02-10 |
| RS67481B1 (sr) | 2025-12-31 |
| EP4192839B1 (en) | 2025-10-01 |
| EP4192839A1 (en) | 2023-06-14 |
| WO2022029704A1 (en) | 2022-02-10 |
| LT4192839T (lt) | 2025-11-25 |
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