PL419744A1 - 4'-Amino-4-carboxychalcone and method for obtaining 4'-amino-4-carboxychalcone - Google Patents
4'-Amino-4-carboxychalcone and method for obtaining 4'-amino-4-carboxychalconeInfo
- Publication number
- PL419744A1 PL419744A1 PL419744A PL41974416A PL419744A1 PL 419744 A1 PL419744 A1 PL 419744A1 PL 419744 A PL419744 A PL 419744A PL 41974416 A PL41974416 A PL 41974416A PL 419744 A1 PL419744 A1 PL 419744A1
- Authority
- PL
- Poland
- Prior art keywords
- carboxychalcone
- amino
- formula
- followed
- substrate
- Prior art date
Links
- GYZNVURPLVVDRJ-UHFFFAOYSA-N 4-[3-(4-aminophenyl)-3-oxoprop-1-enyl]benzoic acid Chemical compound NC1=CC=C(C(C=CC2=CC=C(C=C2)C(=O)O)=O)C=C1 GYZNVURPLVVDRJ-UHFFFAOYSA-N 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- 239000000758 substrate Substances 0.000 abstract 2
- GPRYKVSEZCQIHD-UHFFFAOYSA-N 1-(4-aminophenyl)ethanone Chemical compound CC(=O)C1=CC=C(N)C=C1 GPRYKVSEZCQIHD-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000002244 precipitate Substances 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 238000003756 stirring Methods 0.000 abstract 1
- KUCOHFSKRZZVRO-UHFFFAOYSA-N terephthalaldehyde Chemical compound O=CC1=CC=C(C=O)C=C1 KUCOHFSKRZZVRO-UHFFFAOYSA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Zgłoszony sposób polega na tym, że w kolbie okrągłodennej rozpuszcza się wodorotlenek w mieszaninie wody i alkoholu, następnie dodaje się substratu, którym jest kwas 4-formylobenzaldehydowy o wzorze 2, a następnie drugiego substratu, którym jest 4'-aminoacetofenon o wzorze 1, co stanowi mieszaninę reakcyjną, którą zabezpiecza się przed dostępem światła i pozostawia w temperaturze od 20°C do 30°C na okres od 12 do 48 godzin przy ciągłym mieszaniu, po czym dodaje się 1 -molowego kwasu solnego do momentu wytrącenia osadu, który następnie sączy się pod zmniejszonym ciśnieniem, a otrzymany ekstrakt oczyszcza się. Przedmiotem zgłoszenia jest także 4'-amino-4-karboksychalkon o wzorze 3.The notified method consists in dissolving the hydroxide in a round-bottomed flask in a mixture of water and alcohol, followed by the addition of a substrate which is 4-formylbenzaldehyde acid of formula 2 followed by a second substrate which is 4'-aminoacetophenone of formula 1, which is a reaction mixture which is protected from light and left at a temperature of 20 ° C to 30 ° C for 12 to 48 hours with continuous stirring, after which 1-molar hydrochloric acid is added until a precipitate forms, which is then filtered under reduced pressure, and the obtained extract is purified. The subject of the application is also 4'-amino-4-carboxychalcone of formula 3.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL419744A PL228428B1 (en) | 2016-12-09 | 2016-12-09 | 4'-Amino-4-carboxychalcone and method for obtaining 4'-amino-4-carboxychalcone |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL419744A PL228428B1 (en) | 2016-12-09 | 2016-12-09 | 4'-Amino-4-carboxychalcone and method for obtaining 4'-amino-4-carboxychalcone |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL419744A1 true PL419744A1 (en) | 2017-06-19 |
| PL228428B1 PL228428B1 (en) | 2018-03-30 |
Family
ID=59061629
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL419744A PL228428B1 (en) | 2016-12-09 | 2016-12-09 | 4'-Amino-4-carboxychalcone and method for obtaining 4'-amino-4-carboxychalcone |
Country Status (1)
| Country | Link |
|---|---|
| PL (1) | PL228428B1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL238128B1 (en) * | 2018-04-16 | 2021-07-05 | Politechnika Wroclawska | Application of 3'-amino-4-carboxychalcone |
-
2016
- 2016-12-09 PL PL419744A patent/PL228428B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL228428B1 (en) | 2018-03-30 |
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