PL425038A1 - Nowe peptydowe pochodne płytkopochodnego czynnika wzrostu (PDGF), sposób ich otrzymywania, kompozycja farmaceutyczna oraz zastosowanie - Google Patents

Nowe peptydowe pochodne płytkopochodnego czynnika wzrostu (PDGF), sposób ich otrzymywania, kompozycja farmaceutyczna oraz zastosowanie

Info

Publication number
PL425038A1
PL425038A1 PL425038A PL42503818A PL425038A1 PL 425038 A1 PL425038 A1 PL 425038A1 PL 425038 A PL425038 A PL 425038A PL 42503818 A PL42503818 A PL 42503818A PL 425038 A1 PL425038 A1 PL 425038A1
Authority
PL
Poland
Prior art keywords
application
pdgf
platelet
pharmaceutical composition
growth factor
Prior art date
Application number
PL425038A
Other languages
English (en)
Other versions
PL240667B1 (pl
Inventor
Sylwia RODZIEWICZ-MOTOWIDŁO
Michał PIKUŁA
Milena Deptuła
Przemysław Karpowicz
Piotr Sas
Anna Wardowska
Justyna Sawicka
Maria Dzierżyńska
Franciszek Kasprzykowski
Paweł SOSNOWSKI
Alina Mieczkowska
Natalia Filipowicz
Piotr Madanecki
Arkadiusz Piotrowski
Artur CZUPRYN
Piotr Mucha
Piotr Skowron
Łukasz JANUS
Paweł SACHADYN
Original Assignee
Uniwersytet Gdański
Gdański Uniwersytet Medyczny
Politechnika Gdańska
Instytut Biologii Doświadczalnej Im. Marcelego Nenckiego Polskiej Akademii Nauk
Medventures Spółka Z Ograniczoną Odpowiedzialnością
Pro Science Polska Spółka Z Ograniczoną Odpowiedzialnością
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniwersytet Gdański, Gdański Uniwersytet Medyczny, Politechnika Gdańska, Instytut Biologii Doświadczalnej Im. Marcelego Nenckiego Polskiej Akademii Nauk, Medventures Spółka Z Ograniczoną Odpowiedzialnością, Pro Science Polska Spółka Z Ograniczoną Odpowiedzialnością filed Critical Uniwersytet Gdański
Priority to PL425038A priority Critical patent/PL240667B1/pl
Priority to EP18000305.5A priority patent/EP3546478A1/en
Publication of PL425038A1 publication Critical patent/PL425038A1/pl
Publication of PL240667B1 publication Critical patent/PL240667B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/49—Platelet-derived growth factor [PDGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Przedmiotem zgłoszenia są nowe peptydowe pochodne płytkopochodnego czynnika wzrostu (PDGF) oraz sposób ich otrzymywania. Ponadto, przedmiotem zgłoszenia jest kompozycja farmaceutyczna zawierająca nowe związki oraz zastosowanie tych związków jako środka do leczenia trudno gojących się ran skóry oraz ubytków skórnych o różnej etiologii w tym ran powstałych na tle niewydolności żylnej, niedokrwienia tkanek, miażdżycy, cukrzycy, chorób neurologicznych, zapalnych, ran operacyjnych, ran po zabiegach chemio- i/lub radioterapii i innych stanów patologicznych.
PL425038A 2018-03-26 2018-03-26 Peptyd, będący fragmentem płytkopochodnego czynnika wzrostu do zastosowania jako środek leczniczy do podania na skórę w zaburzeniach naskórka do stymulacji odbudowy naskórka PL240667B1 (pl)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PL425038A PL240667B1 (pl) 2018-03-26 2018-03-26 Peptyd, będący fragmentem płytkopochodnego czynnika wzrostu do zastosowania jako środek leczniczy do podania na skórę w zaburzeniach naskórka do stymulacji odbudowy naskórka
EP18000305.5A EP3546478A1 (en) 2018-03-26 2018-03-30 New peptide derivatives of platelet derived growth factor (pdgf), a method for their preparation, pharmaceutical compositions containing them and application of these compositions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL425038A PL240667B1 (pl) 2018-03-26 2018-03-26 Peptyd, będący fragmentem płytkopochodnego czynnika wzrostu do zastosowania jako środek leczniczy do podania na skórę w zaburzeniach naskórka do stymulacji odbudowy naskórka

Publications (2)

Publication Number Publication Date
PL425038A1 true PL425038A1 (pl) 2019-10-07
PL240667B1 PL240667B1 (pl) 2022-05-16

Family

ID=62110825

Family Applications (1)

Application Number Title Priority Date Filing Date
PL425038A PL240667B1 (pl) 2018-03-26 2018-03-26 Peptyd, będący fragmentem płytkopochodnego czynnika wzrostu do zastosowania jako środek leczniczy do podania na skórę w zaburzeniach naskórka do stymulacji odbudowy naskórka

Country Status (2)

Country Link
EP (1) EP3546478A1 (pl)
PL (1) PL240667B1 (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4385516A4 (en) * 2021-08-12 2025-06-18 Shenzhen Winkey Technology Co., Ltd. Synthetic peptide, cosmetic composition or pharmaceutical composition and use thereof
PL449964A1 (pl) * 2024-10-07 2026-04-13 Gdański Uniwersytet Medyczny Kompozycja farmaceutyczna o działaniu ochronnym i proregeneracyjnym oraz jej zastosowanie

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993016719A2 (en) * 1992-02-26 1993-09-02 Allergan, Inc. Use of platelet derived growth factor in ophthalmic wound healing
WO1993025576A2 (en) * 1992-06-05 1993-12-23 Sri International Peptides having platelet-derived growth factor (pdgf) activity
WO1995011259A1 (en) * 1993-10-22 1995-04-27 Ellerman Pharmaceuticals Limited Platelet-derived growth factor analogues
US5498600A (en) * 1984-10-12 1996-03-12 Zymogenetics, Inc. Biologically active mosaic proteins

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012020326A1 (en) * 2010-03-18 2012-02-16 Novartis Ag Adjuvanted vaccines for serogroup b meningococcus

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5498600A (en) * 1984-10-12 1996-03-12 Zymogenetics, Inc. Biologically active mosaic proteins
WO1993016719A2 (en) * 1992-02-26 1993-09-02 Allergan, Inc. Use of platelet derived growth factor in ophthalmic wound healing
WO1993025576A2 (en) * 1992-06-05 1993-12-23 Sri International Peptides having platelet-derived growth factor (pdgf) activity
WO1995011259A1 (en) * 1993-10-22 1995-04-27 Ellerman Pharmaceuticals Limited Platelet-derived growth factor analogues

Also Published As

Publication number Publication date
PL240667B1 (pl) 2022-05-16
EP3546478A1 (en) 2019-10-02

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