PL425867A1 - Method for extraction of bioactive components of cartilage (tissue), preferably the poultry tissue - Google Patents

Method for extraction of bioactive components of cartilage (tissue), preferably the poultry tissue

Info

Publication number
PL425867A1
PL425867A1 PL425867A PL42586718A PL425867A1 PL 425867 A1 PL425867 A1 PL 425867A1 PL 425867 A PL425867 A PL 425867A PL 42586718 A PL42586718 A PL 42586718A PL 425867 A1 PL425867 A1 PL 425867A1
Authority
PL
Poland
Prior art keywords
tissue
extraction
cartilage
bioactive components
poultry
Prior art date
Application number
PL425867A
Other languages
Polish (pl)
Other versions
PL238656B1 (en
Inventor
Wiesław Kopeć
Anna Pudło
Original Assignee
Uniwersytet Przyrodniczy we Wrocławiu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniwersytet Przyrodniczy we Wrocławiu filed Critical Uniwersytet Przyrodniczy we Wrocławiu
Priority to PL425867A priority Critical patent/PL238656B1/en
Publication of PL425867A1 publication Critical patent/PL425867A1/en
Publication of PL238656B1 publication Critical patent/PL238656B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)
  • Polymers & Plastics (AREA)
  • Cell Biology (AREA)
  • Dermatology (AREA)
  • Materials Engineering (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Przedmiotem zgłoszenia jest sposób ekstrakcji bioaktywnych składników tkanki chrząstki, takich jak żelatyna i glikozaminoglikany, polegający na tym, że ekstrakcję prowadzi się w roztworach wodnych, korzystnie buforowanych, w temperaturze od 50°C do 70°C, z dodatkiem enzymu papainy w ilości powyżej 0,01 mg/g surowca, przy stosunku wagowym rozdrobnionej chrząstki do roztworu w zakresie od 1:2 do 1:10, przy zastosowaniu ultradźwięków, zaś po zakończeniu ekstrakcji składników bioaktywnych oddziela się tkankę łączną, natomiast preparat utrwala się dowolną metodą termiczną.The subject of the application is a method of extracting bioactive components of cartilage tissue, such as gelatin and glycosaminoglycans, whereby the extraction is carried out in aqueous solutions, preferably buffered, at a temperature of 50 ° C to 70 ° C, with the addition of the papain enzyme in an amount above 0 0.01 mg / g of raw material, with the weight ratio of the comminuted cartilage to the solution ranging from 1: 2 to 1:10, using ultrasound, and after the extraction of bioactive ingredients, the connective tissue is separated, and the preparation is fixed by any thermal method.

PL425867A 2018-06-11 2018-06-11 Method for extraction of bioactive components of cartilage (tissue), preferably the poultry tissue PL238656B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL425867A PL238656B1 (en) 2018-06-11 2018-06-11 Method for extraction of bioactive components of cartilage (tissue), preferably the poultry tissue

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL425867A PL238656B1 (en) 2018-06-11 2018-06-11 Method for extraction of bioactive components of cartilage (tissue), preferably the poultry tissue

Publications (2)

Publication Number Publication Date
PL425867A1 true PL425867A1 (en) 2019-12-16
PL238656B1 PL238656B1 (en) 2021-09-20

Family

ID=69054424

Family Applications (1)

Application Number Title Priority Date Filing Date
PL425867A PL238656B1 (en) 2018-06-11 2018-06-11 Method for extraction of bioactive components of cartilage (tissue), preferably the poultry tissue

Country Status (1)

Country Link
PL (1) PL238656B1 (en)

Also Published As

Publication number Publication date
PL238656B1 (en) 2021-09-20

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