PL428568A1 - Flavanone analog and method of its preparation - Google Patents
Flavanone analog and method of its preparationInfo
- Publication number
- PL428568A1 PL428568A1 PL428568A PL42856819A PL428568A1 PL 428568 A1 PL428568 A1 PL 428568A1 PL 428568 A PL428568 A PL 428568A PL 42856819 A PL42856819 A PL 42856819A PL 428568 A1 PL428568 A1 PL 428568A1
- Authority
- PL
- Poland
- Prior art keywords
- flavanone
- analog
- thiosemicarbazide
- preparation
- ethanol
- Prior art date
Links
- ZONYXWQDUYMKFB-UHFFFAOYSA-N SJ000286395 Natural products O1C2=CC=CC=C2C(=O)CC1C1=CC=CC=C1 ZONYXWQDUYMKFB-UHFFFAOYSA-N 0.000 title abstract 3
- 229930003949 flavanone Natural products 0.000 title abstract 3
- 150000002207 flavanone derivatives Chemical class 0.000 title abstract 3
- 235000011981 flavanones Nutrition 0.000 title abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 3
- NFSYORCWJJDWTH-QGOAFFKASA-N [(e)-(2-phenyl-2,3-dihydrochromen-4-ylidene)amino]thiourea Chemical compound O1C2=CC=CC=C2C(=N/NC(=S)N)/CC1C1=CC=CC=C1 NFSYORCWJJDWTH-QGOAFFKASA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000012153 distilled water Substances 0.000 abstract 1
- BRWIZMBXBAOCCF-UHFFFAOYSA-N hydrazinecarbothioamide Chemical compound NNC(N)=S BRWIZMBXBAOCCF-UHFFFAOYSA-N 0.000 abstract 1
- 239000002244 precipitate Substances 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-N sulfuric acid Substances OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Przedmiotem wynalazku jest analog flawanonu, o nazwie chemicznej (E)-1-(2fenylochroman-4-ylideno)- tiosemikarbazyd, o wzorze przedstawionym poniżej. Zgłoszenie obejmuje tez sposób otrzymywania tego związku, który polega na reakcji flawanonu z tiosemikarbazydem w środowisku bezwodnego etanolu w obecności stężonego kwasu siarkowego (VI) w temperaturze 60°C w czasie 24 godzin, po czym mieszaninę reakcyjną z wytrąconym osadem pozostawia się do wystudzenia, a następnie wytrącony osad produktu sączy się pod próżnią i przemywa etanolem oraz destylowaną wodą.The present invention relates to a flavanone analog having the chemical name (E) -1- (2-phenylchroman-4-ylidene) -thiosemicarbazide having the formula shown below. The application also covers the method of obtaining this compound, which consists in reacting flavanone with thiosemicarbazide in anhydrous ethanol in the presence of concentrated sulfuric acid (VI) at a temperature of 60 ° C for 24 hours, then the reaction mixture with a precipitate is left to cool down, and then the precipitated product is filtered under vacuum and washed with ethanol and distilled water.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL428568A PL238799B1 (en) | 2019-01-14 | 2019-01-14 | Flavanone analog and method of its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL428568A PL238799B1 (en) | 2019-01-14 | 2019-01-14 | Flavanone analog and method of its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL428568A1 true PL428568A1 (en) | 2020-07-27 |
| PL238799B1 PL238799B1 (en) | 2021-10-04 |
Family
ID=71733848
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL428568A PL238799B1 (en) | 2019-01-14 | 2019-01-14 | Flavanone analog and method of its preparation |
Country Status (1)
| Country | Link |
|---|---|
| PL (1) | PL238799B1 (en) |
-
2019
- 2019-01-14 PL PL428568A patent/PL238799B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL238799B1 (en) | 2021-10-04 |
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