PL430182A1 - 3-nitrogen derivatives of methyl 2,3-dideoxy-D-ribo-hexopyranosides for use as an HIV-1 reverse transcriptase inhibitor - Google Patents
3-nitrogen derivatives of methyl 2,3-dideoxy-D-ribo-hexopyranosides for use as an HIV-1 reverse transcriptase inhibitorInfo
- Publication number
- PL430182A1 PL430182A1 PL430182A PL43018219A PL430182A1 PL 430182 A1 PL430182 A1 PL 430182A1 PL 430182 A PL430182 A PL 430182A PL 43018219 A PL43018219 A PL 43018219A PL 430182 A1 PL430182 A1 PL 430182A1
- Authority
- PL
- Poland
- Prior art keywords
- dideoxy
- methyl
- ribo
- hiv
- reverse transcriptase
- Prior art date
Links
- 101900297506 Human immunodeficiency virus type 1 group M subtype B Reverse transcriptase/ribonuclease H Proteins 0.000 title abstract 2
- 239000003419 rna directed dna polymerase inhibitor Substances 0.000 title abstract 2
- TWCMVXMQHSVIOJ-UHFFFAOYSA-N Aglycone of yadanzioside D Natural products COC(=O)C12OCC34C(CC5C(=CC(O)C(O)C5(C)C3C(O)C1O)C)OC(=O)C(OC(=O)C)C24 TWCMVXMQHSVIOJ-UHFFFAOYSA-N 0.000 abstract 1
- PLMKQQMDOMTZGG-UHFFFAOYSA-N Astrantiagenin E-methylester Natural products CC12CCC(O)C(C)(CO)C1CCC1(C)C2CC=C2C3CC(C)(C)CCC3(C(=O)OC)CCC21C PLMKQQMDOMTZGG-UHFFFAOYSA-N 0.000 abstract 1
- FEOSBRNHHYNQSH-DIWXZTFISA-N COC(C[C@@H]1N)O[C@H](CO)[C@H]1O Chemical compound COC(C[C@@H]1N)O[C@H](CO)[C@H]1O FEOSBRNHHYNQSH-DIWXZTFISA-N 0.000 abstract 1
- PFOARMALXZGCHY-UHFFFAOYSA-N homoegonol Natural products C1=C(OC)C(OC)=CC=C1C1=CC2=CC(CCCO)=CC(OC)=C2O1 PFOARMALXZGCHY-UHFFFAOYSA-N 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- -1 methyl 3-azido-2,3-dideoxy-D-ribo-hexopyranoside Chemical compound 0.000 abstract 1
- 239000002777 nucleoside Substances 0.000 abstract 1
- 150000003833 nucleoside derivatives Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Przedmiotem wynalazku jest para anomerów 3-azydo-2,3-dideoksy-D-rybo-heksopiranozydów metylu i para anomerów 3-amino-2,3-dideoksy-D-rybo-heksopiranozydów metylu do zastosowania jako nienukleozydowy (tj. zawierający jedynie glikon i grupę metoksylową jako aglikon) inhibitor odwrotnej transkryptazy wirusa HIV-1.The invention relates to a pair of methyl 3-azido-2,3-dideoxy-D-ribo-hexopyranoside anomers and a pair of methyl 3-amino-2,3-dideoxy-D-ribohexopyranoside anomers for use as a non-nucleoside (i.e. and a methoxy group as an aglycone) HIV-1 reverse transcriptase inhibitor.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL430182A PL240353B1 (en) | 2019-06-07 | 2019-06-07 | 3-nitrogen derivatives of methyl 2,3-dideoxy-D-ribo-hexopyranosides for use as an HIV-1 reverse transcriptase inhibitor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL430182A PL240353B1 (en) | 2019-06-07 | 2019-06-07 | 3-nitrogen derivatives of methyl 2,3-dideoxy-D-ribo-hexopyranosides for use as an HIV-1 reverse transcriptase inhibitor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL430182A1 true PL430182A1 (en) | 2020-12-14 |
| PL240353B1 PL240353B1 (en) | 2022-03-21 |
Family
ID=73727738
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL430182A PL240353B1 (en) | 2019-06-07 | 2019-06-07 | 3-nitrogen derivatives of methyl 2,3-dideoxy-D-ribo-hexopyranosides for use as an HIV-1 reverse transcriptase inhibitor |
Country Status (1)
| Country | Link |
|---|---|
| PL (1) | PL240353B1 (en) |
-
2019
- 2019-06-07 PL PL430182A patent/PL240353B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL240353B1 (en) | 2022-03-21 |
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