PL432401A1 - 3-methoxybenzaldehyde oxime ethyl ether and method of its preparation - Google Patents
3-methoxybenzaldehyde oxime ethyl ether and method of its preparationInfo
- Publication number
- PL432401A1 PL432401A1 PL432401A PL43240119A PL432401A1 PL 432401 A1 PL432401 A1 PL 432401A1 PL 432401 A PL432401 A PL 432401A PL 43240119 A PL43240119 A PL 43240119A PL 432401 A1 PL432401 A1 PL 432401A1
- Authority
- PL
- Poland
- Prior art keywords
- ethyl ether
- reaction
- methoxybenzaldehyde oxime
- preparation
- oxime ethyl
- Prior art date
Links
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 title abstract 6
- VDCBJAPSEUTPTQ-TWGQIWQCSA-N (nz)-n-[(3-methoxyphenyl)methylidene]hydroxylamine Chemical compound COC1=CC=CC(\C=N/O)=C1 VDCBJAPSEUTPTQ-TWGQIWQCSA-N 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 abstract 3
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 abstract 1
- 238000010934 O-alkylation reaction Methods 0.000 abstract 1
- 239000012043 crude product Substances 0.000 abstract 1
- 239000002274 desiccant Substances 0.000 abstract 1
- 239000012153 distilled water Substances 0.000 abstract 1
- HVTICUPFWKNHNG-UHFFFAOYSA-N iodoethane Chemical compound CCI HVTICUPFWKNHNG-UHFFFAOYSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000012044 organic layer Substances 0.000 abstract 1
- 239000002304 perfume Substances 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 238000005292 vacuum distillation Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Wynalazek ujawnia eter etylowy oksymu 3-metoksybenzaldehydu o wzorze 1 wykorzystywany jako środek zapachowy. Wynalazek ujawnia również sposób wytwarzania eteru etylowego oksymu 3-metoksybenzaldehydu o wzorze 1, polega na tym, że oksym 3-metoksybenzaldehydu poddaje się reakcji O-alkilowania jodoetanem, przy czym reakcję prowadzi się w kolbie na mieszadle magnetycznym w obecności dimetylosulfotlenku jako rozpuszczalnika przez 24 godziny, a po zakończeniu reakcji rozcieńcza się mieszaninę reakcyjną wodą destylowaną i umieszcza całość w rozdzielaczu, następnie mieszaninę ekstrahuje się trzykrotnie heksanem, a połączone warstwy organiczne suszy się bezwodnym siarczanem magnezu, następnie odfiltrowuje się środek suszący i odparowuje rozpuszczalniki, a surowy produkt oczyszcza się za pomocą frakcyjnej destylacji próżniowej.The invention discloses 3-methoxybenzaldehyde oxime ethyl ether of the formula 1 used as a perfume. The invention also discloses a process for the preparation of 3-methoxybenzaldehyde oxime ethyl ether of the formula 1, which consists in subjecting the 3-methoxybenzaldehyde oxime to an O-alkylation reaction with iodoethane, the reaction being carried out in a flask on a magnetic stirrer in the presence of dimethylsulfoxide as a solvent for 24 hours. and after completion of the reaction, the reaction mixture is diluted with distilled water and placed in a separating funnel, then the mixture is extracted three times with hexane, and the combined organic layers are dried over anhydrous magnesium sulfate, then the drying agent is filtered off and the solvents are evaporated, and the crude product is purified by fractional vacuum distillation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL432401A PL240177B1 (en) | 2019-12-24 | 2019-12-24 | 3-methoxybenzaldehyde oxime ethyl ether and method of its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL432401A PL240177B1 (en) | 2019-12-24 | 2019-12-24 | 3-methoxybenzaldehyde oxime ethyl ether and method of its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL432401A1 true PL432401A1 (en) | 2021-06-28 |
| PL240177B1 PL240177B1 (en) | 2022-02-28 |
Family
ID=76547968
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL432401A PL240177B1 (en) | 2019-12-24 | 2019-12-24 | 3-methoxybenzaldehyde oxime ethyl ether and method of its preparation |
Country Status (1)
| Country | Link |
|---|---|
| PL (1) | PL240177B1 (en) |
-
2019
- 2019-12-24 PL PL432401A patent/PL240177B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL240177B1 (en) | 2022-02-28 |
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