PL434650A1 - Veterinary composition for treatment and/or prevention of diseases caused by protozoa of the genus Eimeria in animals, containing as an active ingredient glaucin or extract of the herb Siwiec (Glaucium sp.) and method of its preparation - Google Patents
Veterinary composition for treatment and/or prevention of diseases caused by protozoa of the genus Eimeria in animals, containing as an active ingredient glaucin or extract of the herb Siwiec (Glaucium sp.) and method of its preparationInfo
- Publication number
- PL434650A1 PL434650A1 PL434650A PL43465020A PL434650A1 PL 434650 A1 PL434650 A1 PL 434650A1 PL 434650 A PL434650 A PL 434650A PL 43465020 A PL43465020 A PL 43465020A PL 434650 A1 PL434650 A1 PL 434650A1
- Authority
- PL
- Poland
- Prior art keywords
- siwiec
- glaucium
- extract
- active ingredient
- protozoa
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 7
- 241000557129 Glaucium Species 0.000 title abstract 3
- 239000004480 active ingredient Substances 0.000 title abstract 3
- 241000223924 Eimeria Species 0.000 title abstract 2
- 241001465754 Metazoa Species 0.000 title abstract 2
- 230000006806 disease prevention Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 239000003054 catalyst Substances 0.000 abstract 3
- RUZIUYOSRDWYQF-HNNXBMFYSA-N (S)-glaucine Chemical compound CN1CCC2=CC(OC)=C(OC)C3=C2[C@@H]1CC1=C3C=C(OC)C(OC)=C1 RUZIUYOSRDWYQF-HNNXBMFYSA-N 0.000 abstract 2
- DABPOQZSGVNAAS-UHFFFAOYSA-N Glaucocalactone Natural products O=CC12C3C(C4)OC(=O)C2C(C)(C)CCC1OC(=O)C13CC4C(=C)C1OC(=O)C DABPOQZSGVNAAS-UHFFFAOYSA-N 0.000 abstract 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract 2
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 abstract 2
- 239000007795 chemical reaction product Substances 0.000 abstract 2
- 229940113086 glaucine Drugs 0.000 abstract 2
- 229930004041 glaucine Natural products 0.000 abstract 2
- 229910052751 metal Inorganic materials 0.000 abstract 2
- 239000002184 metal Substances 0.000 abstract 2
- 150000007524 organic acids Chemical class 0.000 abstract 2
- 235000005985 organic acids Nutrition 0.000 abstract 2
- 238000010992 reflux Methods 0.000 abstract 2
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 abstract 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 abstract 1
- ZOKXTWBITQBERF-UHFFFAOYSA-N Molybdenum Chemical compound [Mo] ZOKXTWBITQBERF-UHFFFAOYSA-N 0.000 abstract 1
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 abstract 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 229910052797 bismuth Inorganic materials 0.000 abstract 1
- JCXGWMGPZLAOME-UHFFFAOYSA-N bismuth atom Chemical compound [Bi] JCXGWMGPZLAOME-UHFFFAOYSA-N 0.000 abstract 1
- 229910052804 chromium Inorganic materials 0.000 abstract 1
- 239000011651 chromium Substances 0.000 abstract 1
- 229910017052 cobalt Inorganic materials 0.000 abstract 1
- 239000010941 cobalt Substances 0.000 abstract 1
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 abstract 1
- 229910052802 copper Inorganic materials 0.000 abstract 1
- 239000010949 copper Substances 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 229910052742 iron Inorganic materials 0.000 abstract 1
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 abstract 1
- 238000002156 mixing Methods 0.000 abstract 1
- 229910052750 molybdenum Inorganic materials 0.000 abstract 1
- 239000011733 molybdenum Substances 0.000 abstract 1
- 229910052759 nickel Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052711 selenium Inorganic materials 0.000 abstract 1
- 239000011669 selenium Substances 0.000 abstract 1
- 239000011701 zinc Substances 0.000 abstract 1
- 229910052725 zinc Inorganic materials 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Przedmiotem wynalazku jest weterynaryjna kompozycja do leczenia i/lub zapobiegania chorób wywoływanych przez pierwotniaki z rodzaju Eimeria u zwierząt zawierająca jako substancję czynną glaucynę albo wyciąg z ziela Siwca (Glaucium sp.), charakteryzująca się tym, że wspomniana substancja czynna występuje w postaci kompleksu z mieszaniną kwasów organicznych i metalem. Kolejnym przedmiotem wynalazku jest sposób wytwarzania wspomnianej kompozycji, który obejmuje następujące etapy: a) zmieszanie wyciągu z ziela Siwca (Glaucium sp.) z mieszaniną kwasów organicznych i dodanie katalizatora albo wprowadzenie katalizatora do mieszaniny kwasów i dodanie glaucyny; b) dodawanie metalu wybranego z grupy obejmującej molibden kobalt, nikiel chrom, cynk, bizmut, miedź, mangan, selen, żelazo, ich sole, lub tlenki; c) ogrzewanie mieszaniny z katalizatorem uzyskanej w etapie b) do temperatury wrzenia oraz kontynuowanie ogrzewania w temperaturze wrzenia pod chłodnicą zwrotną przez 20 - 120 minut; d) odstawienie produktu reakcji do wystygnięcia na okres od 10 do 24 godzin; e) filtrowanie ostudzonego produktu reakcji.The subject of the invention is a veterinary composition for the treatment and / or prevention of diseases caused by protozoa of the genus Eimeria in animals, containing as active ingredient glaucine or extract of the herb Siwiec (Glaucium sp.), Characterized in that said active ingredient is in the form of a complex with a mixture organic acids and metal. Another subject of the invention is a process for the preparation of said composition, which comprises the following steps: a) mixing the extract of Siwiec (Glaucium sp.) With a mixture of organic acids and adding the catalyst or introducing the catalyst to the mixture of acids and adding glaucine; b) adding a metal selected from the group consisting of molybdenum, cobalt, nickel, chromium, zinc, bismuth, copper, manganese, selenium, iron, their salts, or oxides; c) heating the catalyst mixture obtained in step b) to reflux temperature and continuing to reflux for 20-120 minutes; d) allowing the reaction product to cool for a period of 10 to 24 hours; e) filtering the cooled reaction product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL434650A PL243401B1 (en) | 2020-07-13 | 2020-07-13 | Veterinary composition for treatment and/or prevention of diseases caused by protozoa of the genus Eimeria in animals, containing as an active ingredient glaucin or extract of the herb Siwiec (Glaucium sp.) and method of its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL434650A PL243401B1 (en) | 2020-07-13 | 2020-07-13 | Veterinary composition for treatment and/or prevention of diseases caused by protozoa of the genus Eimeria in animals, containing as an active ingredient glaucin or extract of the herb Siwiec (Glaucium sp.) and method of its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL434650A1 true PL434650A1 (en) | 2022-01-17 |
| PL243401B1 PL243401B1 (en) | 2023-08-21 |
Family
ID=80111469
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL434650A PL243401B1 (en) | 2020-07-13 | 2020-07-13 | Veterinary composition for treatment and/or prevention of diseases caused by protozoa of the genus Eimeria in animals, containing as an active ingredient glaucin or extract of the herb Siwiec (Glaucium sp.) and method of its preparation |
Country Status (1)
| Country | Link |
|---|---|
| PL (1) | PL243401B1 (en) |
-
2020
- 2020-07-13 PL PL434650A patent/PL243401B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL243401B1 (en) | 2023-08-21 |
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