PL438511A1 - Sposób jednoczesnego otrzymywania3β,7α,17β-trihydroksy-androst-5-enu i 3β,7β,17β-trihydroksy-androst-5-enu - Google Patents

Sposób jednoczesnego otrzymywania3β,7α,17β-trihydroksy-androst-5-enu i 3β,7β,17β-trihydroksy-androst-5-enu

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Publication number
PL438511A1
PL438511A1 PL438511A PL43851121A PL438511A1 PL 438511 A1 PL438511 A1 PL 438511A1 PL 438511 A PL438511 A PL 438511A PL 43851121 A PL43851121 A PL 43851121A PL 438511 A1 PL438511 A1 PL 438511A1
Authority
PL
Poland
Prior art keywords
androst
trihydroxy
ene
simultaneous preparation
simultaneous
Prior art date
Application number
PL438511A
Other languages
English (en)
Other versions
PL244020B1 (pl
Inventor
Paulina Łyczko
Anna Panek
Alina Świzdor
Monika Urbaniak
Łukasz Stępień
Original Assignee
Uniwersytet Przyrodniczy we Wrocławiu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniwersytet Przyrodniczy we Wrocławiu filed Critical Uniwersytet Przyrodniczy we Wrocławiu
Priority to PL438511A priority Critical patent/PL244020B1/pl
Publication of PL438511A1 publication Critical patent/PL438511A1/pl
Publication of PL244020B1 publication Critical patent/PL244020B1/pl

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00Preparation of steroids
    • C12P33/06Hydroxylating
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0018Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
    • C07J1/0022Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00Preparation of steroids
    • C12P33/12Acting on D ring
    • C12P33/16Acting at 17 position
    • C12P33/18Hydroxylating at 17 position
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/645Fungi ; Processes using fungi

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Wynalazek dotyczy jednoczesnego sposobu otrzymywania 3β,7α, 17β-trihydroksy-androst-5-enu i 3β,7β,17β-trihydroksy-androst-5-enu, o wzorach 2 i 3, na drodze mikrobiologicznej redukcji, w której jako substrat stosuje się 7-okso-DHEA, o wzorze 1, przy użyciu systemu enzymatycznego grzyba strzępkowego Piptoporus betulinus AM39.
PL438511A 2021-07-16 2021-07-16 Sposób jednoczesnego otrzymywania 3β,7α,17β-trihydroksyandrost- 5-enu i 3β,7β,17β-trihydroksy-androst-5-enu PL244020B1 (pl)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL438511A PL244020B1 (pl) 2021-07-16 2021-07-16 Sposób jednoczesnego otrzymywania 3β,7α,17β-trihydroksyandrost- 5-enu i 3β,7β,17β-trihydroksy-androst-5-enu

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL438511A PL244020B1 (pl) 2021-07-16 2021-07-16 Sposób jednoczesnego otrzymywania 3β,7α,17β-trihydroksyandrost- 5-enu i 3β,7β,17β-trihydroksy-androst-5-enu

Publications (2)

Publication Number Publication Date
PL438511A1 true PL438511A1 (pl) 2023-01-23
PL244020B1 PL244020B1 (pl) 2023-11-20

Family

ID=84982724

Family Applications (1)

Application Number Title Priority Date Filing Date
PL438511A PL244020B1 (pl) 2021-07-16 2021-07-16 Sposób jednoczesnego otrzymywania 3β,7α,17β-trihydroksyandrost- 5-enu i 3β,7β,17β-trihydroksy-androst-5-enu

Country Status (1)

Country Link
PL (1) PL244020B1 (pl)

Also Published As

Publication number Publication date
PL244020B1 (pl) 2023-11-20

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