PL438720A1 - Sposób otrzymywania 1-(1'-hydroksyetylo)-9-oksabicyklo[4.3.0]nonan-8-onu - Google Patents

Sposób otrzymywania 1-(1'-hydroksyetylo)-9-oksabicyklo[4.3.0]nonan-8-onu Download PDF

Info

Publication number
PL438720A1
PL438720A1 PL438720A PL43872021A PL438720A1 PL 438720 A1 PL438720 A1 PL 438720A1 PL 438720 A PL438720 A PL 438720A PL 43872021 A PL43872021 A PL 43872021A PL 438720 A1 PL438720 A1 PL 438720A1
Authority
PL
Poland
Prior art keywords
nonan
oxabicyclo
hydroxyethyl
formula
obtaining
Prior art date
Application number
PL438720A
Other languages
English (en)
Other versions
PL243850B1 (pl
Inventor
Marcelina Mazur
Aleksandra Pawlak
Witold Gładkowski
Karolina Przysiężna
Bożena Obmińska-Mrukowicz
Original Assignee
Uniwersytet Przyrodniczy we Wrocławiu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniwersytet Przyrodniczy we Wrocławiu filed Critical Uniwersytet Przyrodniczy we Wrocławiu
Priority to PL438720A priority Critical patent/PL243850B1/pl
Publication of PL438720A1 publication Critical patent/PL438720A1/pl
Publication of PL243850B1 publication Critical patent/PL243850B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/65—Absidia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Przedmiotem zgłoszenia jest sposób otrzymywania optycznie czynnego 1-(1'-hydroksyetylo)-9-oksabicyklo[4.3.0]nonan-8-onu polega na tym, że 1-(1'-chloroetylo)-9-oksabicyklo[4.3.0]nonan-8-on o wzorze 1 poddaje się mikrobiologicznym przekształceniom w kulturze szczepu Absidia glauca AM177 otrzymując 1-(1'-hydroksyetylo)-9-oksabicyklo[4.3.0]nonan-8-on o wzorze 2, który następnie oczyszcza się metodą chromatografii kolumnowej. 1-(1'-Hydroksyetylo)-9-oksabicyklo[4.3.0]nonan-8-on o wzorze 2 może znaleźć zastosowanie w farmacji jako związek o działaniu antynowotworowym.
PL438720A 2021-08-10 2021-08-10 Sposób otrzymywania 1-(1’-hydroksyetylo)-9-oksabicyklo[4.3.0] nonan-8-onu PL243850B1 (pl)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL438720A PL243850B1 (pl) 2021-08-10 2021-08-10 Sposób otrzymywania 1-(1’-hydroksyetylo)-9-oksabicyklo[4.3.0] nonan-8-onu

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL438720A PL243850B1 (pl) 2021-08-10 2021-08-10 Sposób otrzymywania 1-(1’-hydroksyetylo)-9-oksabicyklo[4.3.0] nonan-8-onu

Publications (2)

Publication Number Publication Date
PL438720A1 true PL438720A1 (pl) 2023-02-13
PL243850B1 PL243850B1 (pl) 2023-10-23

Family

ID=85176190

Family Applications (1)

Application Number Title Priority Date Filing Date
PL438720A PL243850B1 (pl) 2021-08-10 2021-08-10 Sposób otrzymywania 1-(1’-hydroksyetylo)-9-oksabicyklo[4.3.0] nonan-8-onu

Country Status (1)

Country Link
PL (1) PL243850B1 (pl)

Also Published As

Publication number Publication date
PL243850B1 (pl) 2023-10-23

Similar Documents

Publication Publication Date Title
MX2021005047A (es) Compuestos de 6-azabenzimidazol sustituidos como inhibidores de hpk1.
MA47165B1 (fr) Inhibiteurs de la poly-adp-ribose polymérase (parp)
MA47079B1 (fr) Composés amino-triazolopyidines et leur utilisation pour traiter le cancer
JP2014527996A5 (pl)
MA40955B1 (fr) 2-amino-6-(difluorométhyl)-5,5-difluoro-6-phényl-3,4,5,6-tétrahydropyridines comme inhibiteurs de bace1
BR112022002149A2 (pt) Composição adequada para transfectar uma molécula de ácido nucleico em uma célula, métodos para transfecção in vitro ou ex vivo de células vivas e para a produção e usos in vitro ou ex vivo da composição
MX2024001202A (es) Derivados de heteroarilos biciclicos como inhibidores de ectonucleotido pirofosfatasa fosfodiesterasa 1
MA37886B1 (fr) Nouvelles pyridinones bicycliques
EA201790942A1 (ru) ТРИФТОРМЕТИЛОВЫЕ СПИРТЫ КАК МОДУЛЯТОРЫ RORγt
BR112021017223A2 (pt) Composto de carboxilato de quinolina, método de preparação do composto, usos do composto e da composição, composição, e, método para controlar bactérias ou doenças causadas pelas mesmas
PE20142318A1 (es) Formulaciones de (+)-2-[1-(3-etoxi-4-metoxi-fenil)-2-metansulfonil-etil]-4-acetilaminoisoindolin-1,3-diona
AR100101A1 (es) Cepas de streptomyces microflavus y métodos de uso de las mismas para controlar enfermedades y plagas en plantas
MA38410B1 (fr) Composés d'azétidinyloxyphénylpyrrolidine
PL438720A1 (pl) Sposób otrzymywania 1-(1'-hydroksyetylo)-9-oksabicyklo[4.3.0]nonan-8-onu
PL438719A1 (pl) 1-(1'-Hydroksyetylo)-9-oksabicyklo[4.3.0]nonan-8-on oraz sposób otrzymywania 1-(1' hydroksyetylo)-9-oksabicyklo[4.3.0]nonan-8-onu
MA39229A1 (fr) Pyrrolidines, térahydrofuranes et cyclopentanes substitués utiles en tant qu'antagonistes des récepteurs des orexines
BR112014015360A2 (pt) métodos para melhorar o rendimento da cultura
PL438721A1 (pl) Sposób otrzymywania 1-(1'-hydroksyetylo)-9-oksabicyklo[4.3.0]nonan-8-onu
CA3156268A1 (en) CDK5 SUBSTITUTE 1,6-NAPHTYRIDINE INHIBITORS
PL429348A1 (pl) (+)-rel-(1R.6R,1'R)-1-(1'-Chloroetylo)-9--oksabicyklo[4.3.0]nonan-8-on oraz sposób otrzymywania (+)-rel-(1R.6R,1'R)-1-(1'-chloroetylo)-9--oksabicyklo[4.3.0]nonan-8-onu
PL429347A1 (pl) (-)-rel-(1R,6R,1'R)-1-(1'-Chloroetylo)-9-oksabicyklo[4.3.0.]nonan-8-on oraz sposób otrzymywania (-)-rel-(1R,6R,1'R)-1-(1'-chloroetylo)-9-oksabicyklo[4.3.0.]nonan-8-onu
PL429344A1 (pl) (-)-rel-(1R,6R,1'R)-1-(1'-Bromoetylo)-9-oksabicyklo[4.3.0]nonan-8-on oraz sposób otrzymywania (-)-rel-(1R,6R,1'R)-1-(1'-bromoetylo)-9-oksabicyklo[4.3.0]nonan-8-onu
PL429349A1 (pl) (-)-rel-(1R,6R,1'R)-1-(1'-Jodoetylo)-9-oksabicyklo[4.3.0]nonan-8-on oraz sposób otrzymywania (-)-rel-(1R,6R,1'R)-1-(1'-jodoetylo)-9-oksabicyklo[4.3.0]nonan-8-onu
FR3085036B1 (fr) Procede de synthese de la vitamine a
BR112016008257A2 (pt) moduladores de roryt de álcool quinolínico secundário