PL449442A1 - Method for manufacturing multi-component microspheres - Google Patents

Method for manufacturing multi-component microspheres

Info

Publication number
PL449442A1
PL449442A1 PL449442A PL44944224A PL449442A1 PL 449442 A1 PL449442 A1 PL 449442A1 PL 449442 A PL449442 A PL 449442A PL 44944224 A PL44944224 A PL 44944224A PL 449442 A1 PL449442 A1 PL 449442A1
Authority
PL
Poland
Prior art keywords
microspheres
mixture
weight concentration
component
manufacturing multi
Prior art date
Application number
PL449442A
Other languages
Polish (pl)
Inventor
Marta Tsirigotis-Maniecka
Izabela Pawlaczyk-Graja
Original Assignee
Politechnika Wrocławska
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Politechnika Wrocławska filed Critical Politechnika Wrocławska
Priority to PL449442A priority Critical patent/PL449442A1/en
Publication of PL449442A1 publication Critical patent/PL449442A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Inorganic Chemistry (AREA)
  • Manufacturing Of Micro-Capsules (AREA)

Abstract

Zgłoszenie ujawnia sposób wytwarzania wieloskładnikowych mikrosfer polegający na tym, że stosuje się środek roślinny w postaci makrocząsteczek o charakterze polisacharydowym, o masie cząsteczkowej > 4 kDa, otrzymanego z liści poziomki pospolitej o stężeniu wagowym od 0,1% do 85%; do którego dodaje się nośnik, (maltodekstrynę) o stężeniu wagowym od 10% do 60%; substancję czynną; substancje pomocnicze (olej i środek powierzchniowo czynny), po czym całość wprowadza się do zbiornika zasilającego suszarki rozpyłowej, skąd przy użyciu pompy perystaltycznej mieszanina jest podawana do urządzenia rozpyłowego, a następnie mieszanina jest rozpylana do wnętrza komory suszącej, po czym odparowuje się rozpuszczalnik przy temperaturze wlotowej powietrza suszącego od 110°C do 180°C i temperaturze wylotowej powietrza od 70°C do 90°C, następnie mikrosfery suszy się i otrzymuje się mikrosfery o średnicy od 10 µm do 1 mm, z rdzeniem zestalonym lub ciekłym.The application discloses a method for producing multi-component microspheres consisting in using a plant agent in the form of polysaccharide macromolecules with a molecular weight of > 4 kDa, obtained from the leaves of common strawberry at a weight concentration of 0.1% to 85%; to which a carrier (maltodextrin) at a weight concentration of 10% to 60% is added; an active substance; auxiliary substances (oil and surfactant), then the whole is introduced into the feed tank of the spray dryer, from where the mixture is fed to the spray device using a peristaltic pump, and then the mixture is sprayed into the interior of the drying chamber, after which the solvent is evaporated at the inlet temperature of the drying air from 110°C to 180°C and the outlet temperature from 70°C to 90°C, then the microspheres are dried and microspheres with a diameter from 10 µm to 1 mm are obtained, with a solid or liquid core.

PL449442A 2024-08-05 2024-08-05 Method for manufacturing multi-component microspheres PL449442A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL449442A PL449442A1 (en) 2024-08-05 2024-08-05 Method for manufacturing multi-component microspheres

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL449442A PL449442A1 (en) 2024-08-05 2024-08-05 Method for manufacturing multi-component microspheres

Publications (1)

Publication Number Publication Date
PL449442A1 true PL449442A1 (en) 2026-02-09

Family

ID=98694618

Family Applications (1)

Application Number Title Priority Date Filing Date
PL449442A PL449442A1 (en) 2024-08-05 2024-08-05 Method for manufacturing multi-component microspheres

Country Status (1)

Country Link
PL (1) PL449442A1 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL211520B1 (en) * 2006-08-21 2012-05-31 Politechnika Wroclawska The manner of production of inhibiting agent and blood coagulation
US8337914B2 (en) * 2002-02-27 2012-12-25 Access Business Group International Llc Dietary food supplement containing natural cyclooxygenase inhibitors and methods for inhibiting pain and inflammation
PL216634B1 (en) * 2005-09-03 2014-04-30 Sacutelanda Tomasz Ślanda Adam Tia Spółka Cywilna Produkcja Handel Usługi Pipe holder
US11612179B2 (en) * 2017-08-23 2023-03-28 Miguel Enrique Jesus Malnati Ramos Method for producing a nanoemulsion with encapsulated natural antioxidants for preserving fresh and minimally processed foods, and the nanoemulsion thus produced

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8337914B2 (en) * 2002-02-27 2012-12-25 Access Business Group International Llc Dietary food supplement containing natural cyclooxygenase inhibitors and methods for inhibiting pain and inflammation
PL216634B1 (en) * 2005-09-03 2014-04-30 Sacutelanda Tomasz Ślanda Adam Tia Spółka Cywilna Produkcja Handel Usługi Pipe holder
PL211520B1 (en) * 2006-08-21 2012-05-31 Politechnika Wroclawska The manner of production of inhibiting agent and blood coagulation
US11612179B2 (en) * 2017-08-23 2023-03-28 Miguel Enrique Jesus Malnati Ramos Method for producing a nanoemulsion with encapsulated natural antioxidants for preserving fresh and minimally processed foods, and the nanoemulsion thus produced

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