PL452422A1 - Sposób określania właściwości przeciwzapalnych czwartorzędowych soli amoniowych zawierających anion pochodzący od kwasu nikotynowego oraz kation N-alkilonikotynamidowy z użyciem albuminy jaja kurzego - Google Patents

Sposób określania właściwości przeciwzapalnych czwartorzędowych soli amoniowych zawierających anion pochodzący od kwasu nikotynowego oraz kation N-alkilonikotynamidowy z użyciem albuminy jaja kurzego

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Publication number
PL452422A1
PL452422A1 PL452422A PL45242225A PL452422A1 PL 452422 A1 PL452422 A1 PL 452422A1 PL 452422 A PL452422 A PL 452422A PL 45242225 A PL45242225 A PL 45242225A PL 452422 A1 PL452422 A1 PL 452422A1
Authority
PL
Poland
Prior art keywords
alkylnicotinamide
ovalbumin
cation
determining
quaternary ammonium
Prior art date
Application number
PL452422A
Other languages
English (en)
Inventor
Adriana Olejniczak
Michał NIEMCZAK
Original Assignee
Politechnika Poznańska
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Politechnika Poznańska filed Critical Politechnika Poznańska
Priority to PL452422A priority Critical patent/PL452422A1/pl
Publication of PL452422A1 publication Critical patent/PL452422A1/pl

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/77—Ovalbumin

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Przedmiotem zgłoszenia jest sposób określania właściwości przeciwzapalnych czwartorzędowych soli amoniowych zawierających anion pochodzący od kwasu nikotynowego oraz kation N-alkilonikotynamidowy, o wzorze ogólnym 1, gdzie R oznacza podstawnik alkilowy zawierający od 6 do 12 atomów węgla, z u życiem albuminy jaja kurzego.
PL452422A 2025-06-20 2025-06-20 Sposób określania właściwości przeciwzapalnych czwartorzędowych soli amoniowych zawierających anion pochodzący od kwasu nikotynowego oraz kation N-alkilonikotynamidowy z użyciem albuminy jaja kurzego PL452422A1 (pl)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL452422A PL452422A1 (pl) 2025-06-20 2025-06-20 Sposób określania właściwości przeciwzapalnych czwartorzędowych soli amoniowych zawierających anion pochodzący od kwasu nikotynowego oraz kation N-alkilonikotynamidowy z użyciem albuminy jaja kurzego

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL452422A PL452422A1 (pl) 2025-06-20 2025-06-20 Sposób określania właściwości przeciwzapalnych czwartorzędowych soli amoniowych zawierających anion pochodzący od kwasu nikotynowego oraz kation N-alkilonikotynamidowy z użyciem albuminy jaja kurzego

Publications (1)

Publication Number Publication Date
PL452422A1 true PL452422A1 (pl) 2026-08-03

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PL452422A PL452422A1 (pl) 2025-06-20 2025-06-20 Sposób określania właściwości przeciwzapalnych czwartorzędowych soli amoniowych zawierających anion pochodzący od kwasu nikotynowego oraz kation N-alkilonikotynamidowy z użyciem albuminy jaja kurzego

Country Status (1)

Country Link
PL (1) PL452422A1 (pl)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005067927A2 (en) * 2004-01-12 2005-07-28 Pharmena Sp Z O.O. The use of quaternary pyridinium salts as vasoprotective agents
WO2007065281A1 (en) * 2005-12-09 2007-06-14 Cerecon Ag Quaternary 3 -amido, n-methylpyridinium salts as anti -inflammatory agents

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005067927A2 (en) * 2004-01-12 2005-07-28 Pharmena Sp Z O.O. The use of quaternary pyridinium salts as vasoprotective agents
WO2007065281A1 (en) * 2005-12-09 2007-06-14 Cerecon Ag Quaternary 3 -amido, n-methylpyridinium salts as anti -inflammatory agents

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BUŠIĆ, V. I IN.,: "Croatica chemica acta, 2022, 95 (1), 31-38", NOVEL SYNTHETIC ROUTES TO QUATERNARY PYRIDINIUM SALTS AND THEIR ANTIFUNGAL ACTIVITY, DOI: 10.5562/cca3903 *
RAD E.Y. I IN.,: "Eur J Nutr. 2024; 63(6): 2011-2024.", THE EFFECT OF NIACIN ON INFLAMMATORY MARKERS AND ADIPOKINES: A SYSTEMATIC REVIEW AND META-ANALYSIS OF INTERVENTIONAL STUDIES, DOI: 10.1007/s00394-024-03425-8 *