PT1015467E - Derivados de eritromicina em ponte 6,9- - Google Patents

Derivados de eritromicina em ponte 6,9-

Info

Publication number
PT1015467E
PT1015467E PT98944680T PT98944680T PT1015467E PT 1015467 E PT1015467 E PT 1015467E PT 98944680 T PT98944680 T PT 98944680T PT 98944680 T PT98944680 T PT 98944680T PT 1015467 E PT1015467 E PT 1015467E
Authority
PT
Portugal
Prior art keywords
eritromycin
bridge
derivatives
eritromycin derivatives
Prior art date
Application number
PT98944680T
Other languages
English (en)
Inventor
Yat Sun Or
Daniel T Chu
Richard F Clark
Jacob J Plattner
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of PT1015467E publication Critical patent/PT1015467E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
PT98944680T 1997-09-08 1998-09-01 Derivados de eritromicina em ponte 6,9- PT1015467E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/925,582 US5780605A (en) 1997-09-08 1997-09-08 6,9-bridged erythromycin derivatives

Publications (1)

Publication Number Publication Date
PT1015467E true PT1015467E (pt) 2004-05-31

Family

ID=25451953

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98944680T PT1015467E (pt) 1997-09-08 1998-09-01 Derivados de eritromicina em ponte 6,9-

Country Status (24)

Country Link
US (1) US5780605A (pt)
EP (1) EP1015467B1 (pt)
JP (1) JP2001515915A (pt)
KR (1) KR20010023756A (pt)
CN (1) CN1269803A (pt)
AR (1) AR015434A1 (pt)
AT (1) ATE257484T1 (pt)
AU (1) AU9216298A (pt)
BG (1) BG104288A (pt)
BR (1) BR9812148A (pt)
CA (1) CA2301643A1 (pt)
CO (1) CO4970722A1 (pt)
DE (1) DE69821009T2 (pt)
DK (1) DK1015467T3 (pt)
ES (1) ES2213915T3 (pt)
HU (1) HUP0003571A2 (pt)
IL (1) IL134220A0 (pt)
NO (1) NO20001169L (pt)
PL (1) PL339137A1 (pt)
PT (1) PT1015467E (pt)
SK (1) SK3032000A3 (pt)
TR (1) TR200000620T2 (pt)
WO (1) WO1999012947A1 (pt)
ZA (1) ZA987688B (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7910558B2 (en) * 2002-05-13 2011-03-22 Enanta Pharmaceuticals, Inc. Bridged macrocyclic compounds and processes for the preparation thereof
US7273853B2 (en) * 2002-05-13 2007-09-25 Enanta Pharmaceuticals, Inc. 6-11 bicyclic ketolide derivatives
US6841664B2 (en) * 2002-07-25 2005-01-11 Enanra Pharmaceuticals, Inc. 6,11-4-carbon bridged ketolides
US7464097B2 (en) * 2002-08-16 2008-12-09 Sap Ag Managing data integrity using a filter condition
AR043050A1 (es) * 2002-09-26 2005-07-13 Rib X Pharmaceuticals Inc Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos
CN1780846A (zh) * 2003-03-05 2006-05-31 Rib－X医药品有限公司 双官能杂环化合物及其制备和使用方法
WO2005042554A1 (en) * 2003-10-30 2005-05-12 Rib-X Pharmaceuticals, Inc. Bifunctional macrolide heterocyclic compounds and methods of making and using the same
JP2007512256A (ja) * 2003-11-18 2007-05-17 リブ−エックス ファーマシューティカルズ，インコーポレイテッド 二官能性マクロライド複素環化合物ならびにこれらを製造する方法およびこれらを使用する方法
WO2005067564A2 (en) * 2004-01-07 2005-07-28 Enanta Pharmaceuticals, Inc. 6-11 bicyclic erythromycin derivatives
WO2005070113A2 (en) * 2004-01-09 2005-08-04 Enanta Pharmaceuticals, Inc. 9n-substituted 6-11 bicyclic erythromycin derivatives
WO2005080408A1 (en) * 2004-01-23 2005-09-01 Enanta Pharmaceuticals, Inc. Bridged macrocyclic compounds and processes for the preparation thereof
US7384921B2 (en) * 2004-02-20 2008-06-10 Enanta Pharmaceuticals, Inc. Polymorphic forms of 6-11 bicyclic ketolide derivatives
JP5383037B2 (ja) * 2004-02-27 2014-01-08 リブ−エックス ファーマシューティカルズ，インコーポレイテッド 大環状化合物およびそれらを製造し使用する方法
US7384922B2 (en) * 2005-05-04 2008-06-10 Enanta Pharmaceuticals, Inc. 6-11 bridged oxime erythromycin derivatives
JP2008540432A (ja) * 2005-05-04 2008-11-20 エナンタ ファーマシューティカルズ インコーポレイテッド ６−１１橋かけオキシムエリスロマイシン誘導体
US20060252710A1 (en) * 2005-05-04 2006-11-09 Guoqiang Wang 6-11 Bridged oxime erythromycin derivatives
US8273720B2 (en) * 2007-09-17 2012-09-25 Enanta Pharmaceuticals, Inc. 6,11-bicyclolides: bridged biaryl macrolide derivatives
ES2691252T3 (es) * 2007-09-17 2018-11-26 Enanta Pharmaceuticals, Inc. Macrólidos de biarilo con puente en 6,11
US8354383B2 (en) * 2007-09-17 2013-01-15 Enanta Pharmaceuticals, Inc. 6,11-bridged biaryl macrolides
TW200946109A (en) * 2008-05-09 2009-11-16 Enanta Pharm Inc Anti-bacterial activity of 9-hydroxy derivatives 6, 11-bicyclolides

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6248696A (ja) * 1985-08-27 1987-03-03 Kanegafuchi Chem Ind Co Ltd Ｎ−〔１（ｓ）−エトキシカルボニル−３−フエニルプロピル〕−ｌ−アラニル−ｌ−プロリンの製造法
KR960000434B1 (ko) * 1986-12-17 1996-01-06 다이쇼 세이야꾸 가부시끼가이샤 에리스로마이신 a유도체 및 그의 제조 방법
HK1010054A1 (en) * 1992-01-21 1999-06-11 Abbott Laboratories 4"-deoxyerythromycin derivatives
ATE135707T1 (de) * 1992-04-22 1996-04-15 Taisho Pharmaceutical Co Ltd 5-0-desosaminylerythronolid a derivate
MY113693A (en) * 1992-05-26 2002-05-31 Chugai Pharmaceutical Co Ltd Erythromycin derivatives having an enterokinesis stimulating action
HRP930014A2 (en) * 1993-01-08 1994-08-31 Pliva Pharm & Chem Works 9-deoxo-9a-aza-11-deoxy-9a-homoeritromycin a 9a, 11-cyclic carbamates
FR2719587B1 (fr) * 1994-05-03 1996-07-12 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
US5712253A (en) * 1996-06-18 1998-01-27 Abbott Laboratories Macrocyclic 13-membered ring derivatives of erythromycins A and B

Also Published As

Publication number Publication date
ATE257484T1 (de) 2004-01-15
ES2213915T3 (es) 2004-09-01
SK3032000A3 (en) 2000-07-11
WO1999012947A1 (en) 1999-03-18
TR200000620T2 (tr) 2000-09-21
PL339137A1 (en) 2000-12-04
NO20001169L (no) 2000-04-05
DE69821009D1 (de) 2004-02-12
AU9216298A (en) 1999-03-29
ZA987688B (en) 1999-02-24
KR20010023756A (ko) 2001-03-26
EP1015467A1 (en) 2000-07-05
US5780605A (en) 1998-07-14
DE69821009T2 (de) 2004-11-18
EP1015467B1 (en) 2004-01-07
DK1015467T3 (da) 2004-05-03
CN1269803A (zh) 2000-10-11
NO20001169D0 (no) 2000-03-07
IL134220A0 (en) 2001-04-30
CO4970722A1 (es) 2000-11-07
AR015434A1 (es) 2001-05-02
HUP0003571A2 (hu) 2001-02-28
CA2301643A1 (en) 1999-03-18
BR9812148A (pt) 2000-07-18
JP2001515915A (ja) 2001-09-25
BG104288A (bg) 2001-01-31

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