PT102721A - Compostos macrociclicos tetrapirrolicos com rendimento quantico de oxigenio singuleto adequado a terapia fotodinamica e processos para a sua preparacao - Google Patents

Compostos macrociclicos tetrapirrolicos com rendimento quantico de oxigenio singuleto adequado a terapia fotodinamica e processos para a sua preparacao

Info

Publication number
PT102721A
PT102721A PT102721A PT10272102A PT102721A PT 102721 A PT102721 A PT 102721A PT 102721 A PT102721 A PT 102721A PT 10272102 A PT10272102 A PT 10272102A PT 102721 A PT102721 A PT 102721A
Authority
PT
Portugal
Prior art keywords
singulium
tetrapyrolic
processes
preparation
photodynamic therapy
Prior art date
Application number
PT102721A
Other languages
English (en)
Other versions
PT102721B (pt
Inventor
Antonio M D A Rocha Goncalves
Marta Pineiro
Armenio C Serra
Original Assignee
Cipan Companhia Industr Prod D
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cipan Companhia Industr Prod D filed Critical Cipan Companhia Industr Prod D
Priority to PT102721A priority Critical patent/PT102721B/pt
Priority to AT03734703T priority patent/ATE441648T1/de
Priority to ES03734703T priority patent/ES2333006T3/es
Priority to DE60329075T priority patent/DE60329075D1/de
Priority to EP03734703A priority patent/EP1472259B1/en
Priority to PCT/EP2003/000829 priority patent/WO2003064427A1/en
Publication of PT102721A publication Critical patent/PT102721A/pt
Publication of PT102721B publication Critical patent/PT102721B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Epoxy Resins (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
PT102721A 2002-02-01 2002-02-01 Compostos macrocíclicos tetrapirrólicos com rendimento quântico de oxigénio singuleto adequado à terapia fotodinâmica e processos para a sua preparação PT102721B (pt)

Priority Applications (6)

Application Number Priority Date Filing Date Title
PT102721A PT102721B (pt) 2002-02-01 2002-02-01 Compostos macrocíclicos tetrapirrólicos com rendimento quântico de oxigénio singuleto adequado à terapia fotodinâmica e processos para a sua preparação
AT03734703T ATE441648T1 (de) 2002-02-01 2003-01-28 Tetrapyrrol-macrocyclen als photodynamische mittel
ES03734703T ES2333006T3 (es) 2002-02-01 2003-01-28 Macrociclos tetrapirrolicos como agentes fotodinamicos.
DE60329075T DE60329075D1 (en) 2002-02-01 2003-01-28 Tetrapyrrol-macrocyclen als photodynamische mittel
EP03734703A EP1472259B1 (en) 2002-02-01 2003-01-28 Tetrapyrrolic macrocycles as photodynamic agents
PCT/EP2003/000829 WO2003064427A1 (en) 2002-02-01 2003-01-28 Tetrapyrrolic macrocycles as photodynamic agents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PT102721A PT102721B (pt) 2002-02-01 2002-02-01 Compostos macrocíclicos tetrapirrólicos com rendimento quântico de oxigénio singuleto adequado à terapia fotodinâmica e processos para a sua preparação

Publications (2)

Publication Number Publication Date
PT102721A true PT102721A (pt) 2003-08-29
PT102721B PT102721B (pt) 2011-01-24

Family

ID=27656540

Family Applications (1)

Application Number Title Priority Date Filing Date
PT102721A PT102721B (pt) 2002-02-01 2002-02-01 Compostos macrocíclicos tetrapirrólicos com rendimento quântico de oxigénio singuleto adequado à terapia fotodinâmica e processos para a sua preparação

Country Status (6)

Country Link
EP (1) EP1472259B1 (pt)
AT (1) ATE441648T1 (pt)
DE (1) DE60329075D1 (pt)
ES (1) ES2333006T3 (pt)
PT (1) PT102721B (pt)
WO (1) WO2003064427A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2877943B1 (fr) * 2004-11-16 2008-09-05 Univ De Coimbra Nouveaux derives de porphyrine, notamment chlorines et/ou bacteriochlorine, et leurs applications en therapie photodynamique
GB0819594D0 (en) * 2008-10-24 2008-12-03 Univ Coimbrra Process
WO2011161065A1 (en) 2010-06-25 2011-12-29 Fundação Padre Antonio Vieira Macrocyclic tetrapyrrolic compound of the family of porphyrins, chlorins and bacteriochlorins as photosensitizers for photodynamic therapy
RU2538261C2 (ru) * 2013-03-22 2015-01-10 Федеральное государственное унитарное предприятие "Государственный научный центр "Научно-исследовательский институт органических полупродуктов и красителей" (ФГУП "ГНЦ "НИОПИК") Гетерогенный сенсибилизатор и способ фотообеззараживания воды
WO2017051435A1 (en) * 2015-09-22 2017-03-30 Council Of Scientific And Industrial Research Chlorin based compounds, a process for preparation thereof and use as photodynamic therapeutic agents and fluorescent probes
RU2771237C1 (ru) * 2021-06-04 2022-04-28 федеральное государственное автоносное образовательное учреждение высшего образования «Национальный исследовательский Томский политехнический университет» Сенсибилизатор для фотодинамического разрушения опухолевых клеток

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE123749T1 (de) * 1987-04-17 1995-06-15 David H Dolphin Porphyrine, verfahren zu deren herstellung und verwendungen.
GB8805849D0 (en) * 1988-03-11 1988-04-13 Efamol Holdings Porphyrins & cancer treatment
CZ278391B6 (en) * 1990-08-08 1993-12-15 Ustav Organicke Chemie A Bioch Substituted 5,15-diphenylporphyrins and process for preparing thereof
WO1997000874A1 (en) * 1995-06-20 1997-01-09 Pdt Pharmaceuticals, Inc. Efficient functionalization of porphyrin derivatives
US6620929B1 (en) * 1999-04-14 2003-09-16 University Of British Columbia 1,3-Dipolar cycloadditions to polypyrrolic macrocycles
GB0001455D0 (en) * 2000-01-21 2000-03-15 Scotia Holdings Plc Porphyrins and related compounds
GB0005855D0 (en) * 2000-03-10 2000-05-03 Scotia Holdings Plc Compounds for pdt
CA2376001A1 (en) * 2000-03-30 2001-10-11 Martinus Bernardus Vrouenraets Photodynamic therapy compounds
JP3385468B2 (ja) * 2000-06-12 2003-03-10 科学技術振興事業団 新規な拡張ポルフィリン及び拡張ポルフィリンの合成法

Also Published As

Publication number Publication date
ATE441648T1 (de) 2009-09-15
WO2003064427A1 (en) 2003-08-07
ES2333006T3 (es) 2010-02-16
PT102721B (pt) 2011-01-24
EP1472259A1 (en) 2004-11-03
DE60329075D1 (en) 2009-10-15
EP1472259B1 (en) 2009-09-02

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 20110119

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20150803