PT1086096E - Benzamidas com substituintes etra-hidrofuraniloxi como inibidores da fosfodiesterase 4 - Google Patents
Benzamidas com substituintes etra-hidrofuraniloxi como inibidores da fosfodiesterase 4Info
- Publication number
- PT1086096E PT1086096E PT99926441T PT99926441T PT1086096E PT 1086096 E PT1086096 E PT 1086096E PT 99926441 T PT99926441 T PT 99926441T PT 99926441 T PT99926441 T PT 99926441T PT 1086096 E PT1086096 E PT 1086096E
- Authority
- PT
- Portugal
- Prior art keywords
- inhibitors
- hydrofuraniloxi
- substituts
- etra
- benzamides
- Prior art date
Links
- 229940054066 benzamide antipsychotics Drugs 0.000 title 1
- 150000003936 benzamides Chemical class 0.000 title 1
- 239000002587 phosphodiesterase IV inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Furan Compounds (AREA)
- Pyrane Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98110710 | 1998-06-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1086096E true PT1086096E (pt) | 2003-12-31 |
Family
ID=8232103
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT99926441T PT1086096E (pt) | 1998-06-10 | 1999-05-27 | Benzamidas com substituintes etra-hidrofuraniloxi como inibidores da fosfodiesterase 4 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US6303789B1 (pt) |
| EP (1) | EP1086096B1 (pt) |
| JP (1) | JP2002517495A (pt) |
| AT (1) | ATE245642T1 (pt) |
| AU (1) | AU757198B2 (pt) |
| CA (1) | CA2334979A1 (pt) |
| DE (1) | DE59906365D1 (pt) |
| DK (1) | DK1086096T3 (pt) |
| ES (1) | ES2205833T3 (pt) |
| IL (1) | IL140070A (pt) |
| PT (1) | PT1086096E (pt) |
| SI (1) | SI1086096T1 (pt) |
| WO (1) | WO1999064414A1 (pt) |
| ZA (1) | ZA200007210B (pt) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6953774B2 (en) * | 2000-08-11 | 2005-10-11 | Applied Research Systems Ars Holding N.V. | Methods of inducing ovulation |
| DK1463493T3 (da) * | 2001-12-14 | 2008-02-04 | Serono Lab | Fremgangsmåder til at inducere æglösning ved anvendelse af en ikke polypeptid-cAMP-niveaumodulator |
| ES2351161T3 (es) * | 2005-05-03 | 2011-02-01 | Ranbaxy Laboratories Limited | Inhibidores de la fosfodiesterasa a base de azol. |
| JP2009506069A (ja) | 2005-08-26 | 2009-02-12 | ブレインセルス,インコーポレイティド | ムスカリン性受容体調節による神経発生 |
| EP2258359A3 (en) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation with sabcomelin |
| US7985756B2 (en) | 2005-10-21 | 2011-07-26 | Braincells Inc. | Modulation of neurogenesis by PDE inhibition |
| WO2007053596A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| WO2007134077A2 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | 5 ht receptor mediated neurogenesis |
| WO2007134136A2 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| EP2068872A1 (en) | 2006-09-08 | 2009-06-17 | Braincells, Inc. | Combinations containing a 4-acylaminopyridine derivative |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| US20090182035A1 (en) * | 2007-04-11 | 2009-07-16 | Alcon Research, Ltd. | Use of a combination of olopatadine and cilomilast to treat non-infectious rhinitis and allergic conjunctivitis |
| RU2009141592A (ru) * | 2007-04-11 | 2011-05-20 | Алькон Рисерч, Лтд. (Us) | ПРИМЕНЕНИЕ ИНГИБИТОРА TNFα В СОЧЕТАНИИ С АНТИГИСТАМИННЫМ СРЕДСТВОМ ДЛЯ ЛЕЧЕНИЯ АЛЛЕРГИЧЕСКОГО РИНИТА И АЛЛЕРГИЧЕСКОГО КОНЪЮНКТИВИТА |
| WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| RU2012117141A (ru) * | 2009-10-01 | 2013-11-10 | Алькон Рисерч, Лтд. | Композиции олопатадина и способы их применения |
| EP2804603A1 (en) | 2012-01-10 | 2014-11-26 | President and Fellows of Harvard College | Beta-cell replication promoting compounds and methods of their use |
| US12472241B2 (en) | 2018-12-28 | 2025-11-18 | Regeneron Pharmaceuticals, Inc. | Treatment of respiratory disorders with arachidonate 15-lipoxygenase (ALOX15) inhibitors |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE150447T1 (de) | 1992-06-15 | 1997-04-15 | Celltech Therapeutics Ltd | Trisubstituierte phenylderivate als selektive phosphodiesterase iv inhibitoren |
| ES2227519T3 (es) | 1992-07-28 | 2005-04-01 | Aventis Pharma Limited | Inhibidores de c-amp-fosfodiesterasa. |
| GB9401460D0 (en) * | 1994-01-26 | 1994-03-23 | Rhone Poulenc Rorer Ltd | Compositions of matter |
| NZ290420A (en) | 1994-07-22 | 1999-01-28 | Byk Gulden Lomberg Chem Fab | Phenyl or pyridyl-amide substituted dihydro benzofurans; medicaments |
| CN1100773C (zh) * | 1995-12-05 | 2003-02-05 | 达尔文发现有限公司 | 苯并呋喃羧酸胺和磺酰胺 |
| ATE229516T1 (de) | 1996-08-19 | 2002-12-15 | Altana Pharma Ag | Benzofuran-4-carboxamide |
-
1999
- 1999-05-27 US US09/701,566 patent/US6303789B1/en not_active Expired - Fee Related
- 1999-05-27 PT PT99926441T patent/PT1086096E/pt unknown
- 1999-05-27 ES ES99926441T patent/ES2205833T3/es not_active Expired - Lifetime
- 1999-05-27 DK DK99926441T patent/DK1086096T3/da active
- 1999-05-27 CA CA002334979A patent/CA2334979A1/en not_active Abandoned
- 1999-05-27 IL IL14007099A patent/IL140070A/en not_active IP Right Cessation
- 1999-05-27 AT AT99926441T patent/ATE245642T1/de not_active IP Right Cessation
- 1999-05-27 JP JP2000553423A patent/JP2002517495A/ja not_active Withdrawn
- 1999-05-27 WO PCT/EP1999/003669 patent/WO1999064414A1/de not_active Ceased
- 1999-05-27 DE DE59906365T patent/DE59906365D1/de not_active Expired - Fee Related
- 1999-05-27 EP EP99926441A patent/EP1086096B1/de not_active Expired - Lifetime
- 1999-05-27 AU AU43700/99A patent/AU757198B2/en not_active Ceased
- 1999-05-27 SI SI9930424T patent/SI1086096T1/xx unknown
-
2000
- 2000-12-06 ZA ZA200007210A patent/ZA200007210B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE245642T1 (de) | 2003-08-15 |
| IL140070A0 (en) | 2002-02-10 |
| WO1999064414A1 (de) | 1999-12-16 |
| CA2334979A1 (en) | 1999-12-16 |
| ZA200007210B (en) | 2002-03-06 |
| EP1086096B1 (de) | 2003-07-23 |
| DE59906365D1 (de) | 2003-08-28 |
| AU4370099A (en) | 1999-12-30 |
| DK1086096T3 (da) | 2003-11-10 |
| JP2002517495A (ja) | 2002-06-18 |
| AU757198B2 (en) | 2003-02-06 |
| ES2205833T3 (es) | 2004-05-01 |
| US6303789B1 (en) | 2001-10-16 |
| IL140070A (en) | 2004-06-20 |
| SI1086096T1 (en) | 2003-12-31 |
| EP1086096A1 (de) | 2001-03-28 |
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