PT1200103E - Xénon como antagonista de nmda para neuroprotecção - Google Patents
Xénon como antagonista de nmda para neuroprotecção Download PDFInfo
- Publication number
- PT1200103E PT1200103E PT00948171T PT00948171T PT1200103E PT 1200103 E PT1200103 E PT 1200103E PT 00948171 T PT00948171 T PT 00948171T PT 00948171 T PT00948171 T PT 00948171T PT 1200103 E PT1200103 E PT 1200103E
- Authority
- PT
- Portugal
- Prior art keywords
- xenon
- neuroprotection
- nmda antagonist
- modulating
- activity
- Prior art date
Links
- 229910052724 xenon Inorganic materials 0.000 title abstract 3
- FHNFHKCVQCLJFQ-UHFFFAOYSA-N xenon atom Chemical compound [Xe] FHNFHKCVQCLJFQ-UHFFFAOYSA-N 0.000 title abstract 3
- 239000003703 n methyl dextro aspartic acid receptor blocking agent Substances 0.000 title abstract 2
- 230000004112 neuroprotection Effects 0.000 title 1
- 102000004868 N-Methyl-D-Aspartate Receptors Human genes 0.000 abstract 3
- 108090001041 N-Methyl-D-Aspartate Receptors Proteins 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 241000124008 Mammalia Species 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Inorganic Chemistry (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9917822.0A GB9917822D0 (en) | 1999-07-29 | 1999-07-29 | Nmda antagonist |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1200103E true PT1200103E (pt) | 2008-09-17 |
Family
ID=10858166
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT00948171T PT1200103E (pt) | 1999-07-29 | 2000-07-28 | Xénon como antagonista de nmda para neuroprotecção |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6274633B1 (pt) |
| EP (1) | EP1200103B1 (pt) |
| JP (1) | JP5088997B2 (pt) |
| AT (1) | ATE404211T1 (pt) |
| AU (1) | AU778097B2 (pt) |
| CA (1) | CA2280310C (pt) |
| DE (1) | DE60039878D1 (pt) |
| ES (1) | ES2311466T3 (pt) |
| GB (1) | GB9917822D0 (pt) |
| PT (1) | PT1200103E (pt) |
| RU (1) | RU2257902C2 (pt) |
| WO (1) | WO2001008692A1 (pt) |
| ZA (1) | ZA200200539B (pt) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6979456B1 (en) | 1998-04-01 | 2005-12-27 | Jagotec Ag | Anticancer compositions |
| ES2211151T3 (es) | 1998-08-19 | 2004-07-01 | Skyepharma Canada Inc. | Dispersiones acuosas inyectables de propofol. |
| DE19910986C2 (de) * | 1999-03-11 | 2001-06-07 | Aga Ab | Verwendung von Xenon bei der Behandlung von Neurointoxikationen |
| GB9913677D0 (en) * | 1999-06-11 | 1999-08-11 | Imperial College | Formulation |
| EP1436258A4 (en) * | 2001-03-08 | 2005-03-23 | Univ Emory | PH VALVE DEPENDENT NMDA RECEPTOR ANTAGONISTS |
| GB0209998D0 (en) * | 2002-05-01 | 2002-06-12 | Protexeon Ltd | Use |
| GB0210021D0 (en) | 2002-05-01 | 2002-06-12 | Air Prod & Chem | Ultrasonic gas analyser |
| GB0218153D0 (en) * | 2002-08-05 | 2002-09-11 | Ic Innovations Ltd | An analgesic agent for newborn or retal subjects |
| US7681572B2 (en) * | 2002-08-20 | 2010-03-23 | Aga Ab | Method and devices for administration of therapeutic gases |
| US7337776B2 (en) * | 2002-08-20 | 2008-03-04 | Aga Ab | Methods for easing pain and anxiety from atrial or ventricular defibrillation |
| FR2858233B1 (fr) * | 2003-07-30 | 2008-04-11 | Air Liquide Sante Int | Medicament gazeux inhalable a base de xenon et de protoxyde d'azote |
| WO2005034966A1 (en) * | 2003-10-10 | 2005-04-21 | Protexeon Limited | Use of xenon with hypothermia for treating neonatal asphyxia |
| EP1675597A2 (en) * | 2003-10-21 | 2006-07-05 | Aga Ab | Use of xenon for the prevention of programmed cell death |
| FR2863169B1 (fr) * | 2003-12-08 | 2006-02-10 | Air Liquide Sante Int | Medicament gazeux inhalable a base d'argon pour le traitement des neuro-intoxications |
| GB0520176D0 (en) * | 2005-10-04 | 2005-11-09 | Imp College Innovations Ltd | Use |
| RU2346695C2 (ru) * | 2006-08-15 | 2009-02-20 | Общество с ограниченной ответственностью "Ксиан"(ООО "Ксиан") | Применение ксенона для коррекции патологических изменений в организме, связанных с нарушением антиоксидантного статуса |
| EP1980260A1 (en) | 2007-04-10 | 2008-10-15 | Nicholas Peter Franks | Use of hyperbaric conditions to provide neuroprotection |
| EP1980261A1 (en) | 2007-04-10 | 2008-10-15 | Nicholas Peter Franks | Use of helium with oxygen to provide neuroprotection |
| US8435569B2 (en) * | 2007-04-30 | 2013-05-07 | Nnoxe Pharmaceutiques Inc. | Pharmaceutical composition comprising at least one thrombolytic agent (A) and at least one gas (B) selected from the group consisting of nitrous oxide, argon, xenon, helium, neon |
| KR20100045983A (ko) | 2007-06-29 | 2010-05-04 | 에모리 유니버시티 | 신경보호를 위한 nmda 수용체 길항물질 |
| FR2952305B1 (fr) * | 2009-11-10 | 2012-04-27 | Air Liquide | Medicament inhalable a base de xenon pour traiter ou pour prevenir les dyskinesies |
| CN103565745A (zh) | 2012-08-10 | 2014-02-12 | 德克萨斯州大学系统董事会 | 用于治疗中风的神经保护性脂质体组合物和方法 |
| CA3132914C (en) | 2013-03-15 | 2023-11-07 | The Board Of Regents Of The University Of Texas System | Liquids rich in noble gas and methods of their preparation and use |
| FR3022456B1 (fr) * | 2014-06-20 | 2016-07-15 | Air Liquide | Xenon associe a un antagoniste des recepteurs nmda pour lutter contre une proliferation tumorale dans le systeme nerveux central |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU120307A1 (ru) * | 1949-04-19 | 1958-11-30 | К.М. Салдадзе | Способ приготовлени искусственно-радиоактивных лечебных ванн |
| SU1075632A1 (ru) * | 1982-05-25 | 1985-06-30 | Ордена Трудового Красного Знамени Научно-Исследовательский Институт Экспериментальной Медицины Амн Ссср | Устройство дл моделировани нейрона |
| US5124319A (en) * | 1991-10-11 | 1992-06-23 | American Home Products Corporation | Benzimidazole phosphono-amino acids |
| JP4313435B2 (ja) * | 1995-07-24 | 2009-08-12 | トラスティーズ オブ ボストン ユニバーシティー | プレグネノロンサルフェート誘導体によるnmdaレセプター活性の抑制 |
| DE19709704C2 (de) * | 1997-03-10 | 1999-11-04 | Michael Georgieff | Verwendung einer flüssigen Präparation von Xenon zur intravenösen Verabreichung bei Einleitung und/oder Aufrechterhaltung der Anaesthesie |
| GB9706294D0 (en) * | 1997-03-26 | 1997-05-14 | Glaxo Wellcome Spa | Heterocyclic compound |
| DE69809827D1 (de) * | 1997-03-31 | 2003-01-16 | Korea Res Inst Chem Tech | Chinolinische Sulfid-Derivate als NMDA Rezeptor-Antagonisten und Verfahren zu ihrer Herstellung |
| JPH1171271A (ja) * | 1997-06-27 | 1999-03-16 | Shionogi & Co Ltd | グルコン酸又はその類縁体を含有するnmda受容体拮抗剤 |
| DE19910986C2 (de) * | 1999-03-11 | 2001-06-07 | Aga Ab | Verwendung von Xenon bei der Behandlung von Neurointoxikationen |
-
1999
- 1999-07-29 GB GBGB9917822.0A patent/GB9917822D0/en not_active Ceased
- 1999-08-13 CA CA002280310A patent/CA2280310C/en not_active Expired - Lifetime
- 1999-08-23 US US09/378,806 patent/US6274633B1/en not_active Expired - Lifetime
-
2000
- 2000-07-28 PT PT00948171T patent/PT1200103E/pt unknown
- 2000-07-28 DE DE60039878T patent/DE60039878D1/de not_active Expired - Lifetime
- 2000-07-28 RU RU2002105377/15A patent/RU2257902C2/ru not_active IP Right Cessation
- 2000-07-28 JP JP2001513422A patent/JP5088997B2/ja not_active Expired - Lifetime
- 2000-07-28 EP EP00948171A patent/EP1200103B1/en not_active Revoked
- 2000-07-28 WO PCT/GB2000/002896 patent/WO2001008692A1/en not_active Ceased
- 2000-07-28 ES ES00948171T patent/ES2311466T3/es not_active Expired - Lifetime
- 2000-07-28 AU AU61735/00A patent/AU778097B2/en not_active Ceased
- 2000-07-28 AT AT00948171T patent/ATE404211T1/de not_active IP Right Cessation
-
2002
- 2002-01-22 ZA ZA200200539A patent/ZA200200539B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE60039878D1 (de) | 2008-09-25 |
| CA2280310A1 (en) | 2001-01-29 |
| ATE404211T1 (de) | 2008-08-15 |
| AU6173500A (en) | 2001-02-19 |
| EP1200103A1 (en) | 2002-05-02 |
| ES2311466T3 (es) | 2009-02-16 |
| US6274633B1 (en) | 2001-08-14 |
| GB9917822D0 (en) | 1999-09-29 |
| RU2257902C2 (ru) | 2005-08-10 |
| JP5088997B2 (ja) | 2012-12-05 |
| AU778097B2 (en) | 2004-11-18 |
| JP2003505512A (ja) | 2003-02-12 |
| ZA200200539B (en) | 2002-09-25 |
| EP1200103B1 (en) | 2008-08-13 |
| WO2001008692A1 (en) | 2001-02-08 |
| CA2280310C (en) | 2008-10-14 |
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