PT1200103E - Xénon como antagonista de nmda para neuroprotecção - Google Patents

Xénon como antagonista de nmda para neuroprotecção Download PDF

Info

Publication number
PT1200103E
PT1200103E PT00948171T PT00948171T PT1200103E PT 1200103 E PT1200103 E PT 1200103E PT 00948171 T PT00948171 T PT 00948171T PT 00948171 T PT00948171 T PT 00948171T PT 1200103 E PT1200103 E PT 1200103E
Authority
PT
Portugal
Prior art keywords
xenon
neuroprotection
nmda antagonist
modulating
activity
Prior art date
Application number
PT00948171T
Other languages
English (en)
Inventor
Nicholas P Franks
Mervyn Maze
Original Assignee
Protexeon Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10858166&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1200103(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Protexeon Ltd filed Critical Protexeon Ltd
Publication of PT1200103E publication Critical patent/PT1200103E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Inorganic Chemistry (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT00948171T 1999-07-29 2000-07-28 Xénon como antagonista de nmda para neuroprotecção PT1200103E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9917822.0A GB9917822D0 (en) 1999-07-29 1999-07-29 Nmda antagonist

Publications (1)

Publication Number Publication Date
PT1200103E true PT1200103E (pt) 2008-09-17

Family

ID=10858166

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00948171T PT1200103E (pt) 1999-07-29 2000-07-28 Xénon como antagonista de nmda para neuroprotecção

Country Status (13)

Country Link
US (1) US6274633B1 (pt)
EP (1) EP1200103B1 (pt)
JP (1) JP5088997B2 (pt)
AT (1) ATE404211T1 (pt)
AU (1) AU778097B2 (pt)
CA (1) CA2280310C (pt)
DE (1) DE60039878D1 (pt)
ES (1) ES2311466T3 (pt)
GB (1) GB9917822D0 (pt)
PT (1) PT1200103E (pt)
RU (1) RU2257902C2 (pt)
WO (1) WO2001008692A1 (pt)
ZA (1) ZA200200539B (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6979456B1 (en) 1998-04-01 2005-12-27 Jagotec Ag Anticancer compositions
ES2211151T3 (es) 1998-08-19 2004-07-01 Skyepharma Canada Inc. Dispersiones acuosas inyectables de propofol.
DE19910986C2 (de) * 1999-03-11 2001-06-07 Aga Ab Verwendung von Xenon bei der Behandlung von Neurointoxikationen
GB9913677D0 (en) * 1999-06-11 1999-08-11 Imperial College Formulation
EP1436258A4 (en) * 2001-03-08 2005-03-23 Univ Emory PH VALVE DEPENDENT NMDA RECEPTOR ANTAGONISTS
GB0209998D0 (en) * 2002-05-01 2002-06-12 Protexeon Ltd Use
GB0210021D0 (en) 2002-05-01 2002-06-12 Air Prod & Chem Ultrasonic gas analyser
GB0218153D0 (en) * 2002-08-05 2002-09-11 Ic Innovations Ltd An analgesic agent for newborn or retal subjects
US7681572B2 (en) * 2002-08-20 2010-03-23 Aga Ab Method and devices for administration of therapeutic gases
US7337776B2 (en) * 2002-08-20 2008-03-04 Aga Ab Methods for easing pain and anxiety from atrial or ventricular defibrillation
FR2858233B1 (fr) * 2003-07-30 2008-04-11 Air Liquide Sante Int Medicament gazeux inhalable a base de xenon et de protoxyde d'azote
WO2005034966A1 (en) * 2003-10-10 2005-04-21 Protexeon Limited Use of xenon with hypothermia for treating neonatal asphyxia
EP1675597A2 (en) * 2003-10-21 2006-07-05 Aga Ab Use of xenon for the prevention of programmed cell death
FR2863169B1 (fr) * 2003-12-08 2006-02-10 Air Liquide Sante Int Medicament gazeux inhalable a base d'argon pour le traitement des neuro-intoxications
GB0520176D0 (en) * 2005-10-04 2005-11-09 Imp College Innovations Ltd Use
RU2346695C2 (ru) * 2006-08-15 2009-02-20 Общество с ограниченной ответственностью "Ксиан"(ООО "Ксиан") Применение ксенона для коррекции патологических изменений в организме, связанных с нарушением антиоксидантного статуса
EP1980260A1 (en) 2007-04-10 2008-10-15 Nicholas Peter Franks Use of hyperbaric conditions to provide neuroprotection
EP1980261A1 (en) 2007-04-10 2008-10-15 Nicholas Peter Franks Use of helium with oxygen to provide neuroprotection
US8435569B2 (en) * 2007-04-30 2013-05-07 Nnoxe Pharmaceutiques Inc. Pharmaceutical composition comprising at least one thrombolytic agent (A) and at least one gas (B) selected from the group consisting of nitrous oxide, argon, xenon, helium, neon
KR20100045983A (ko) 2007-06-29 2010-05-04 에모리 유니버시티 신경보호를 위한 nmda 수용체 길항물질
FR2952305B1 (fr) * 2009-11-10 2012-04-27 Air Liquide Medicament inhalable a base de xenon pour traiter ou pour prevenir les dyskinesies
CN103565745A (zh) 2012-08-10 2014-02-12 德克萨斯州大学系统董事会 用于治疗中风的神经保护性脂质体组合物和方法
CA3132914C (en) 2013-03-15 2023-11-07 The Board Of Regents Of The University Of Texas System Liquids rich in noble gas and methods of their preparation and use
FR3022456B1 (fr) * 2014-06-20 2016-07-15 Air Liquide Xenon associe a un antagoniste des recepteurs nmda pour lutter contre une proliferation tumorale dans le systeme nerveux central

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU120307A1 (ru) * 1949-04-19 1958-11-30 К.М. Салдадзе Способ приготовлени искусственно-радиоактивных лечебных ванн
SU1075632A1 (ru) * 1982-05-25 1985-06-30 Ордена Трудового Красного Знамени Научно-Исследовательский Институт Экспериментальной Медицины Амн Ссср Устройство дл моделировани нейрона
US5124319A (en) * 1991-10-11 1992-06-23 American Home Products Corporation Benzimidazole phosphono-amino acids
JP4313435B2 (ja) * 1995-07-24 2009-08-12 トラスティーズ オブ ボストン ユニバーシティー プレグネノロンサルフェート誘導体によるnmdaレセプター活性の抑制
DE19709704C2 (de) * 1997-03-10 1999-11-04 Michael Georgieff Verwendung einer flüssigen Präparation von Xenon zur intravenösen Verabreichung bei Einleitung und/oder Aufrechterhaltung der Anaesthesie
GB9706294D0 (en) * 1997-03-26 1997-05-14 Glaxo Wellcome Spa Heterocyclic compound
DE69809827D1 (de) * 1997-03-31 2003-01-16 Korea Res Inst Chem Tech Chinolinische Sulfid-Derivate als NMDA Rezeptor-Antagonisten und Verfahren zu ihrer Herstellung
JPH1171271A (ja) * 1997-06-27 1999-03-16 Shionogi & Co Ltd グルコン酸又はその類縁体を含有するnmda受容体拮抗剤
DE19910986C2 (de) * 1999-03-11 2001-06-07 Aga Ab Verwendung von Xenon bei der Behandlung von Neurointoxikationen

Also Published As

Publication number Publication date
DE60039878D1 (de) 2008-09-25
CA2280310A1 (en) 2001-01-29
ATE404211T1 (de) 2008-08-15
AU6173500A (en) 2001-02-19
EP1200103A1 (en) 2002-05-02
ES2311466T3 (es) 2009-02-16
US6274633B1 (en) 2001-08-14
GB9917822D0 (en) 1999-09-29
RU2257902C2 (ru) 2005-08-10
JP5088997B2 (ja) 2012-12-05
AU778097B2 (en) 2004-11-18
JP2003505512A (ja) 2003-02-12
ZA200200539B (en) 2002-09-25
EP1200103B1 (en) 2008-08-13
WO2001008692A1 (en) 2001-02-08
CA2280310C (en) 2008-10-14

Similar Documents

Publication Publication Date Title
PT1200103E (pt) Xénon como antagonista de nmda para neuroprotecção
SE9503924D0 (sv) Novel opioid peptides
NZ516347A (en) Indanyl-substituted benzenecarboxamides, process for their preparation, their use as a medicament and pharmaceutical formulations containing them
HUP0003386A3 (en) Use of crf antagonists for the preparation of pharmaceutical compositions treating depression, cardiovascular diseases
AU2002225772A1 (en) Therapeutic agents and methods of use thereof for treating an amyloidogenic disease
BG106095A (bg) Нови лекарствени състави на базата на антихолинергично активни съединения и бета-миметици
MXPA02007942A (es) Derivados de pirrolopirimidinona, procesos de preparacion y uso.
UA66750C2 (en) Substituted 1-phenylpirazole 3-carboxamides, a method for the preparation thereof and intermediary compounds, pharmaceutical composition having affinity to neurotensin receptors
HUP0302474A3 (en) Therapeutically effective tropane derivatives, process for their preparation pharmaceutical compositions containing them and their use
ZA992951B (en) N-substituted aminotetralins as ligands for the neuropeptide Y Y5 receptor useful in the treatment of obesity and other disorders.
MXPA02001306A (es) Composiciones farmaceuticas para el tratamiento de enfermedades del sistema nervioso central y otras enfermedades.
SE9904505D0 (sv) Novel compounds
PL343069A1 (en) Combination for the treatment of alcohol and drug dependence containing an opioid antagonist and a nmda receptor complex modulator
HUP0202186A3 (en) Benzimidazolone derivatives, process for their preparation, pharmaceutical compositions containing them and their use as phosphodiesterase inhibitors for producing pharmaceutical compositions
AR019671A1 (es) Uso de una cantidad terapeuticamente efectiva de (+) norcisaprida o una sal farmacologicamente aceptable de la misma sustancialmente libre de su (-)estereoisomero, para la preparacion de un medicamento
HUP0203320A3 (en) Indolylpiperidine derivatives and their use as antihistaminic and antiallergic agents, process for their preparation, pharmaceutical compositions containing them
MXPA01008993A (es) Tratamiento de combinacion para depresion y ansiedad.
EP1213031A3 (en) Combination treatment for depression, anxiety and psychosis comprising an antidepressant and/or anxiolytic and a D4 receptor antagonist
TW200631956A (en) Azabenzoxazoles for the treatment of CNS disorders
WO2002092565A3 (en) 3-aminoalkyl-2-aryl-indole derivatives and their use as gnrh antagonists
UA70986C2 (uk) Похідні (1-арацил-3-арил-3-піперидилетил)піперидину, спосіб їх отримання та фармацевтична композиція, що має у своєму складі такі похідні
HUP9801925A3 (en) Use of sodium-hydrogen-exchange-inhibitors for producing pharmaceutical compositions treating diseases caused by protozoons
EP1099446A3 (en) Combination treatment for depression and anxiety containing a CNS-penetrant NK-1 receptor antagonist and an antidepressant or anxiolytic agent
HUP0202347A2 (en) N-acylated pseudomycin analogs, process for their preparation, pharmaceutical compositions comprising thereof and their use
MY141756A (en) Use of phenoxyacetic acid derivatives for treating hyperactive bladder