PT1280535E - Processos para a preparacao de polimorfos de claritromicina - Google Patents

Processos para a preparacao de polimorfos de claritromicina

Info

Publication number: PT1280535E
Authority: PT; Portugal
Prior art keywords: processes; preparation; clarithromycin; clarithromycine; polymorphes
Prior art date: 2000-01-11

Application number

PT00986367T

Other languages

English (en)

Inventor

Lifshitz Igor

Avrutov Ilya

Schwartz Edi

Masarwa Basem

Original Assignee

Teva Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-01-11

Filing date

2000-12-15

Publication date

2005-04-29

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22640371&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1280535(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2000-12-15 Application filed by Teva Pharma filed Critical Teva Pharma

2005-04-29 Publication of PT1280535E publication Critical patent/PT1280535E/pt

Links

AGOYDEPGAOXOCK-KCBOHYOISA-N clarithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@](C)([C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)OC)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 AGOYDEPGAOXOCK-KCBOHYOISA-N 0.000 title abstract 8
229960002626 clarithromycin Drugs 0.000 abstract 2
ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 abstract 1
229930006677 Erythromycin A Natural products 0.000 abstract 1
229960003276 erythromycin Drugs 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

PT00986367T 2000-01-11 2000-12-15 Processos para a preparacao de polimorfos de claritromicina PT1280535E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US17547700P	2000-01-11	2000-01-11

Publications (1)

Publication Number	Publication Date
PT1280535E true PT1280535E (pt)	2005-04-29

Family

ID=22640371

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT00986367T PT1280535E (pt)	2000-01-11	2000-12-15	Processos para a preparacao de polimorfos de claritromicina

Country Status (22)

Country	Link
US (2)	US6624292B2 (pt)
EP (1)	EP1280535B1 (pt)
JP (1)	JP2003519661A (pt)
KR (1)	KR20020071012A (pt)
CN (1)	CN1450903A (pt)
AT (1)	ATE288758T1 (pt)
AU (2)	AU2261901A (pt)
BR (1)	BR0016992A (pt)
CA (1)	CA2397092A1 (pt)
DE (1)	DE60018119T2 (pt)
DK (1)	DK1280535T3 (pt)
ES (1)	ES2236023T3 (pt)
HR (1)	HRP20020572A2 (pt)
HU (1)	HUP0204252A3 (pt)
IL (1)	IL150698A0 (pt)
IS (1)	IS6463A (pt)
PL (1)	PL356645A1 (pt)
PT (1)	PT1280535E (pt)
RU (1)	RU2002118308A (pt)
SI (1)	SI1280535T1 (pt)
WO (1)	WO2001051059A1 (pt)
ZA (1)	ZA200205229B (pt)

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PT1254146E (pt) *	1999-12-16	2005-10-31	Teva Pharma	Processos de preparacao de polimeros de claritromicina e novo polimorfo iv
PL356645A1 (en) *	2000-01-11	2004-06-28	Teva Pharmaceutical Industries Ltd.	Processes for preparing clarithromycin polymorphs
US6565882B2 (en) *	2000-02-24	2003-05-20	Advancis Pharmaceutical Corp	Antibiotic composition with inhibitor
US6544555B2 (en)	2000-02-24	2003-04-08	Advancis Pharmaceutical Corp.	Antibiotic product, use and formulation thereof
AU2578701A (en) *	2000-02-29	2001-09-12	Teva Pharma	Processes for preparing clarithromycin and clarithromycin intermediate, essentially oxime-free clarithromycin, and pharmaceutical composition comprising the same
KR20030011797A (ko) *	2000-03-28	2003-02-11	바이오케미 게젤샤프트 엠베하	맛이 차폐된 과립형 입자
US6541014B2 (en) *	2000-10-13	2003-04-01	Advancis Pharmaceutical Corp.	Antiviral product, use and formulation thereof
US20020068078A1 (en) *	2000-10-13	2002-06-06	Rudnic Edward M.	Antifungal product, use and formulation thereof
ES2288898T3 (es) *	2001-08-13	2008-02-01	Fondazione Salvatore Maugeri - Clinica del Lavoro e della Riabilitazione	Uso de composiciones de claritromicina en la fabricacion de un medicamento para el tratamiento de la artritis deformante.
US20060083759A1 (en) *	2002-07-17	2006-04-20	Aleksander Resman	Stabilization of the profile of release of active substances from a formulation
EP1648415A4 (en) *	2003-07-21	2011-11-16	Middlebrook Pharmaceuticals Inc	ANTIBIOTIC PRODUCT, ITS USE AND FORMULATION
CA2533292C (en) *	2003-07-21	2013-12-31	Advancis Pharmaceutical Corporation	Antibiotic product, use and formulation thereof
EP1648418A4 (en) *	2003-07-21	2011-11-16	Middlebrook Pharmaceuticals Inc	ANTIBIOTIC PRODUCT, ITS USE AND FORMULATION
WO2005016311A1 (en) *	2003-08-11	2005-02-24	Advancis Pharmaceutical Corporation	Robust pellet
CA2535398C (en) *	2003-08-12	2013-11-12	Advancis Pharmaceuticals Corporation	Antibiotic product, use and formulation thereof
EP1658034A4 (en) *	2003-08-29	2011-06-22	Middlebrook Pharmaceuticals Inc	ANTIBIOTIC PRODUCT, ITS USE AND FORMULATION
WO2005027877A1 (en) *	2003-09-15	2005-03-31	Advancis Pharmaceutical Corporation	Antibiotic product, use and formulation thereof
WO2005061524A2 (en) *	2003-12-22	2005-07-07	Ranbaxy Laboratories Limited	Process for the preparation of form ii clarithromycin
AU2004308419B2 (en) *	2003-12-24	2011-06-02	Victory Pharma, Inc.	Enhanced absorption of modified release dosage forms
AU2005209318B2 (en) *	2004-01-28	2010-02-11	Cytimmune Sciences, Inc.	Functionalized colloidal metal compositions and methods
US7468428B2 (en) *	2004-03-17	2008-12-23	App Pharmaceuticals, Llc	Lyophilized azithromycin formulation
US20060116336A1 (en) *	2004-03-17	2006-06-01	American Pharmaceutical Partners, Inc.	Lyophilized azithromycin formulation
US8715727B2 (en) *	2004-07-02	2014-05-06	Shionogi Inc.	Tablet for pulsed delivery
JP2009500356A (ja) *	2005-07-07	2009-01-08	エランファーマインターナショナルリミテッド	ナノ粒子クラリスロマイシン製剤
US20070122483A1 (en) *	2005-11-29	2007-05-31	Sharon Myers	Fluocinolone acetonide drug substance polymorphic interconversion
US8778924B2 (en) *	2006-12-04	2014-07-15	Shionogi Inc.	Modified release amoxicillin products
US8357394B2 (en)	2005-12-08	2013-01-22	Shionogi Inc.	Compositions and methods for improved efficacy of penicillin-type antibiotics
US8299052B2 (en)	2006-05-05	2012-10-30	Shionogi Inc.	Pharmaceutical compositions and methods for improved bacterial eradication
US20120219625A1 (en) *	2009-09-02	2012-08-30	Bernard Charles Sherman	Clarithromycin extended-release tablet
EP3578546A1 (en)	2013-11-15	2019-12-11	Akebia Therapeutics Inc.	Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid, compositions, and uses thereof

Family Cites Families (28)

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FR2473525A1 (fr)	1980-01-11	1981-07-17	Roussel Uclaf	Nouvelles oximes derivees de l'erythromycine, leur procede de preparation et leur application comme medicaments
US4331803A (en)	1980-06-04	1982-05-25	Taisho Pharmaceutical Co., Ltd.	Novel erythromycin compounds
JPS60214796A (ja)	1984-04-06	1985-10-28	Taisho Pharmaceut Co Ltd	６−０−メチルエリスロマイシン類の製法
JPS61103890A (ja)	1984-10-26	1986-05-22	Taisho Pharmaceut Co Ltd	６−０−メチルエリスロマイシンａ誘導体
US4670549A (en)	1985-03-18	1987-06-02	Taisho Pharmaceutical Co., Ltd.	Method for selective methylation of erythromycin a derivatives
US4672056A (en)	1985-11-12	1987-06-09	Abbott Laboratories	Erythromycin A derivatives and method of use
US4640910A (en)	1985-11-12	1987-02-03	Abbott Laboratories	Erythromycin A silylated compounds and method of use
KR960000434B1 (ko)	1986-12-17	1996-01-06	다이쇼 세이야꾸 가부시끼가이샤	에리스로마이신 a유도체 및 그의 제조 방법
GB8721165D0 (en)	1987-09-09	1987-10-14	Beecham Group Plc	Chemical compounds
JP2751385B2 (ja)	1988-05-19	1998-05-18	大正製薬株式会社	エリスロマイシンａオキシム及びその塩の製造方法
US5440505A (en) *	1994-01-21	1995-08-08	Intel Corporation	Method and circuitry for storing discrete amounts of charge in a single memory element
US5872229A (en)	1995-11-21	1999-02-16	Abbott Laboratories	Process for 6-O-alkylation of erythromycin derivatives
US5756473A (en)	1995-11-21	1998-05-26	Abbott Laboratories	6-O-methyl erythromycin D and process for making
US5719272A (en)	1996-04-02	1998-02-17	Abbott Laboratories	2'-protected 3'-dimethylamine, 9-etheroxime erythromycin A derivatives
US5837829A (en)	1996-04-02	1998-11-17	Abbott Laboratories	9-oximesilyl erythromycin a derivatives
US5808017A (en)	1996-04-10	1998-09-15	Abbott Laboratories	Process for preparing erythromycin A oxime
US5844105A (en) *	1996-07-29	1998-12-01	Abbott Laboratories	Preparation of crystal form II of clarithromycin
US5858986A (en) *	1996-07-29	1999-01-12	Abbott Laboratories	Crystal form I of clarithromycin
PT915899E (pt) *	1996-07-29	2004-11-30	Abbott Lab	Preparacao da forma cristalina ii da eritromicina
US5945405A (en)	1997-01-17	1999-08-31	Abbott Laboratories	Crystal form O of clarithromycin
US5864023A (en)	1997-02-13	1999-01-26	Abbott Laboratories	3'-N'oxide, 3'-n-dimethylamine, 9-oxime erythromycin a derivatives
US5852180A (en)	1997-11-17	1998-12-22	Abbott Laboratories	Chemical synthesis of 6-O-alkyl erythromycin A
US5932710A (en)	1997-12-01	1999-08-03	Abbott Laboratories	Process for preparing 6-O-alkyl-9-oxime erythromycin B
US5892008A (en)	1997-12-16	1999-04-06	Abbott Laboratories	Process for the preparation of 6-O-methyl erythromycin a using 9-hydroxy erythromycin derivatives
KR100377159B1 (ko)	1998-09-09	2003-08-19	한미약품공업 주식회사	잔류 용매가 없는 클라리스로마이신의 결정형 2의 제조 방법
PT1254146E (pt) *	1999-12-16	2005-10-31	Teva Pharma	Processos de preparacao de polimeros de claritromicina e novo polimorfo iv
PL356645A1 (en) *	2000-01-11	2004-06-28	Teva Pharmaceutical Industries Ltd.	Processes for preparing clarithromycin polymorphs
AU2578701A (en)	2000-02-29	2001-09-12	Teva Pharma	Processes for preparing clarithromycin and clarithromycin intermediate, essentially oxime-free clarithromycin, and pharmaceutical composition comprising the same

2000
- 2000-12-15 PL PL00356645A patent/PL356645A1/xx not_active Application Discontinuation
- 2000-12-15 RU RU2002118308/15A patent/RU2002118308A/ru unknown
- 2000-12-15 CA CA002397092A patent/CA2397092A1/en not_active Abandoned
- 2000-12-15 WO PCT/US2000/033844 patent/WO2001051059A1/en not_active Ceased
- 2000-12-15 AT AT00986367T patent/ATE288758T1/de not_active IP Right Cessation
- 2000-12-15 KR KR1020027008908A patent/KR20020071012A/ko not_active Ceased
- 2000-12-15 AU AU2261901A patent/AU2261901A/xx active Pending
- 2000-12-15 EP EP00986367A patent/EP1280535B1/en not_active Revoked
- 2000-12-15 ES ES00986367T patent/ES2236023T3/es not_active Expired - Lifetime
- 2000-12-15 DE DE60018119T patent/DE60018119T2/de not_active Expired - Fee Related
- 2000-12-15 DK DK00986367T patent/DK1280535T3/da active
- 2000-12-15 JP JP2001551483A patent/JP2003519661A/ja not_active Withdrawn
- 2000-12-15 CN CN00819302A patent/CN1450903A/zh active Pending
- 2000-12-15 PT PT00986367T patent/PT1280535E/pt unknown
- 2000-12-15 AU AU2001222619A patent/AU2001222619C1/en not_active Ceased
- 2000-12-15 IL IL15069800A patent/IL150698A0/xx unknown
- 2000-12-15 HR HR20020572A patent/HRP20020572A2/hr not_active Application Discontinuation
- 2000-12-15 SI SI200030650T patent/SI1280535T1/xx unknown
- 2000-12-15 BR BR0016992-7A patent/BR0016992A/pt not_active Application Discontinuation
- 2000-12-15 HU HU0204252A patent/HUP0204252A3/hu unknown
- 2000-12-15 US US09/736,446 patent/US6624292B2/en not_active Expired - Fee Related
2002
- 2002-06-28 ZA ZA200205229A patent/ZA200205229B/en unknown
- 2002-07-09 IS IS6463A patent/IS6463A/is unknown
2003
- 2003-06-10 US US10/459,178 patent/US6987175B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
HUP0204252A2 (hu)	2003-03-28
RU2002118308A (ru)	2004-02-20
AU2001222619C1 (en)	2006-01-12
IS6463A (is)	2002-07-09
EP1280535B1 (en)	2005-02-09
EP1280535A4 (en)	2003-02-05
AU2001222619B8 (en)	2005-07-14
WO2001051059A1 (en)	2001-07-19
AU2261901A (en)	2001-07-24
HRP20020572A2 (en)	2005-04-30
DE60018119D1 (de)	2005-03-17
EP1280535A1 (en)	2003-02-05
US20020028920A1 (en)	2002-03-07
ATE288758T1 (de)	2005-02-15
CA2397092A1 (en)	2001-07-19
SI1280535T1 (pt)	2005-08-31
US6987175B2 (en)	2006-01-17
JP2003519661A (ja)	2003-06-24
AU2001222619B2 (en)	2005-04-28
CN1450903A (zh)	2003-10-22
KR20020071012A (ko)	2002-09-11
BR0016992A (pt)	2002-12-31
IL150698A0 (en)	2003-02-12
US6624292B2 (en)	2003-09-23
HUP0204252A3 (en)	2003-04-28
PL356645A1 (en)	2004-06-28
ES2236023T3 (es)	2005-07-16
US20030216555A1 (en)	2003-11-20
DE60018119T2 (de)	2006-05-04
DK1280535T3 (da)	2005-04-04
ZA200205229B (en)	2003-06-30

Publication	Publication Date	Title
IS6463A (is)	2002-07-09	Aðferðir til að búa til klaríþrómýsínfjölgervinga
NL1017075A1 (nl)	2001-07-11	Preparaat.
MXPA03004833A (es)	2003-08-19	SISTEMA REMOTO DE SEnALAMIENTO DE HUMEDAD.
MXPA03004761A (es)	2003-08-19	Turboalimentador sin alabes.
MXPA03005222A (es)	2004-03-26	Derivado de metanosulfonamido-benzofurano, su procedimiento de preparacion y su utilizacion como intermediario de sisntesis.
DE60100143D1 (de)	2003-04-30	Freisetzungssystem von Cyclopropenderivaten, welches eine kleinere Wassermenge benützt
MXPA03001590A (es)	2003-06-04	Anticuerpos para la il-1beta humana.
BR0114175B1 (pt)	2009-08-11	transmissão hidromecánica.
MXPA03002452A (es)	2003-06-19	Derivados de resorcinol.
BR0114903A (pt)	2003-10-14	7-azaindóis, sua aplicação como inibidores da fosfodiesterase 4 e processos para a sua preparação
DK1147139T3 (da)	2006-11-13	Vandig copolymerisatdespersion, fremgangsmåde til fremstilling deraf såvel som anvendelse deraf
BR0110478B1 (pt)	2013-10-01	composiÇço aquosa de xampu.
BR0110858B1 (pt)	2012-04-17	métodos para fazer peças de roupa com componentes de fixação.
DK1259474T3 (da)	2009-07-20	Calcium-dicarboxylatethere, fremgangsmåder til fremstilling deraf
IT1319686B1 (it)	2003-10-23	Procedimento di preparazione di citalopram.
BR0114176B1 (pt)	2009-12-01	transmissão hidromecánica.
YU53302A (sh)	2005-06-10	Postupci za pripremanje polimorfa klaritromicina
TW200501726A (en)	2005-01-01	Techniques to perform line qualification
AR025230A1 (es)	2002-11-13	Procedimiento para preparar fosfonometilglicina.
IT249170Y1 (it)	2003-04-03	Raccordo, in particolare raccordo per tubazioni.
ES1045613Y (es)	2001-03-16	Puntal para encofrados.
ITCN990003A0 (it)	1999-04-06	Alternativa vera alla sigaretta,.
ES1048179Y (es)	2001-12-01	Entarimado para fondos de bañera.
NO20001218D0 (no)	2000-03-08	Det kinetisk kvantiserte system, det lineært akselererte system
ECSP993252A (es)	2000-02-24	Macrolidos