PT2706982T - Formas farmacêutica de administração por via nasal contendo naloxona - Google Patents

Formas farmacêutica de administração por via nasal contendo naloxona

Info

Publication number: PT2706982T
Authority: PT; Portugal
Prior art keywords: administration; pharmaceutical forms; nasal route; route containing; containing naloxone
Prior art date: 2011-05-13

Application number

PT127215077T

Other languages

English (en)

Inventor

Strang John

Oksche Alexander

Harris Stephen

Smith Kevin

Helene Jeanne Mottier Lucie

Original Assignee

Euro Celtique Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-05-13

Filing date

2012-05-11

Publication date

2018-03-08

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44658496&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2706982(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2012-05-11 Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa

2018-03-08 Publication of PT2706982T publication Critical patent/PT2706982T/pt

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Emergency Medicine (AREA)
Otolaryngology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Dispersion Chemistry (AREA)
Addiction (AREA)
Inorganic Chemistry (AREA)
Dermatology (AREA)
Psychiatry (AREA)
Toxicology (AREA)
Pain & Pain Management (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

PT127215077T 2011-05-13 2012-05-11 Formas farmacêutica de administração por via nasal contendo naloxona PT2706982T (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP11166076		2011-05-13

Publications (1)

Publication Number	Publication Date
PT2706982T true PT2706982T (pt)	2018-03-08

Family

ID=44658496

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT127215077T PT2706982T (pt)	2011-05-13	2012-05-11	Formas farmacêutica de administração por via nasal contendo naloxona

Country Status (37)

Country	Link
US (8)	US20150018379A1 (pt)
EP (2)	EP2706982B2 (pt)
JP (3)	JP6110367B2 (pt)
KR (2)	KR101873174B1 (pt)
CN (2)	CN107260672A (pt)
AR (1)	AR086391A1 (pt)
AT (1)	AT16553U1 (pt)
AU (2)	AU2012257785B2 (pt)
BR (1)	BR112013029126A2 (pt)
CA (1)	CA2835940C (pt)
CO (1)	CO6821959A2 (pt)
CY (1)	CY1120399T1 (pt)
DE (1)	DE202012013606U1 (pt)
DK (2)	DK2706982T4 (pt)
ES (1)	ES2661838T5 (pt)
HK (1)	HK1255428A1 (pt)
HR (1)	HRP20180233T1 (pt)
HU (1)	HUE036465T2 (pt)
IL (1)	IL229409B (pt)
LT (1)	LT2706982T (pt)
ME (1)	ME02958B (pt)
MX (1)	MX354249B (pt)
MY (1)	MY194947A (pt)
NO (1)	NO2706982T3 (pt)
PH (2)	PH12013502313A1 (pt)
PL (1)	PL2706982T3 (pt)
PT (1)	PT2706982T (pt)
RS (1)	RS57054B1 (pt)
RU (2)	RU2657441C1 (pt)
SG (1)	SG194927A1 (pt)
SI (1)	SI2706982T1 (pt)
SM (1)	SMT201800105T1 (pt)
TR (1)	TR201802716T4 (pt)
TW (1)	TWI486161B (pt)
UA (1)	UA110974C2 (pt)
WO (1)	WO2012156317A2 (pt)
ZA (1)	ZA201308280B (pt)

Families Citing this family (26)

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US8939943B2 (en)	2011-01-26	2015-01-27	Kaleo, Inc.	Medicament delivery device for administration of opioid antagonists including formulations for naloxone
US8627816B2 (en)	2011-02-28	2014-01-14	Intelliject, Inc.	Medicament delivery device for administration of opioid antagonists including formulations for naloxone
MY194947A (en) *	2011-05-13	2022-12-27	Euro Celtique Sa	Intranasal pharmaceutical dosage forms comprising naloxone
CA2875384A1 (en)	2013-12-20	2015-06-20	AntiOP, Inc.	Intranasal naloxone compositions and methods of making and using same
MX365383B (es) *	2014-03-14	2019-05-31	Opiant Pharmaceuticals Inc	Medicamentos de administracion nasal y metodos para su uso.
US9561177B2 (en)	2014-03-14	2017-02-07	Adapt Pharma Limited	Nasal drug products and methods of their use
US10085937B2 (en)	2014-03-14	2018-10-02	Adapt Pharma Limited	Nasal drug products and methods of their use
US9480644B2 (en)	2014-03-14	2016-11-01	Opiant Pharmaceuticals, Inc.	Nasal drug products and methods of their use
US10722510B2 (en)	2014-07-08	2020-07-28	Hikma Pharmaceuticals Usa Inc.	Liquid naloxone spray
US11135155B2 (en)	2014-07-08	2021-10-05	Hikma Pharmaceuticals Usa Inc.	Liquid naloxone spray
WO2016007729A1 (en) *	2014-07-09	2016-01-14	Lightlake Therapeutics Inc.	Co-packaged drug products
US9517307B2 (en)	2014-07-18	2016-12-13	Kaleo, Inc.	Devices and methods for delivering opioid antagonists including formulations for naloxone
WO2017011326A1 (en) *	2015-07-10	2017-01-19	Sanjay Gupta	Nasal foam via cribriform plate for medication delivery to the brain and/or body and for nasal moisturization and hygiene
WO2017049181A1 (en) *	2015-09-17	2017-03-23	Adapt Pharma Limited	Nasal drug products and methods of their use
KR102634829B1 (ko) *	2016-06-24	2024-02-07	오피언트 파마슈티컬스, 인코퍼레이티드	알코올 사용 장애의 치료용 조성물, 장치 및 방법
WO2018034920A1 (en) *	2016-08-17	2018-02-22	Insys Development Company, Inc.	Liquid naloxone spray
AU2020245535B2 (en) *	2019-03-26	2022-06-30	Pinova Therapeutics Inc.	Devices and methods for delivering pharmaceutical compositions
US10729687B1 (en)	2019-07-09	2020-08-04	Orexo Ab	Pharmaceutical composition for nasal delivery
US10653690B1 (en)	2019-07-09	2020-05-19	Orexo Ab	Pharmaceutical composition for nasal delivery
CA3166250A1 (en)	2020-02-05	2021-08-12	Gregory G. Plucinski	Drug products for intranasal administration and uses thereof
WO2021222545A1 (en) *	2020-04-29	2021-11-04	The Texas A&M University System	Naloxone nanoparticle compositions and methods thereof
PT3962455T (pt)	2020-05-18	2022-10-13	Orexo Ab	Nova composição farmacêutica para entrega de fármacos
US11278709B1 (en)	2021-03-12	2022-03-22	Pocket Naloxone Corp.	Drug delivery device and methods for using same
MX2024001659A (es)	2021-08-04	2024-06-26	Indivior Inc	Composiciones y métodos para el tratamiento de la sobredosis por opioides.
GB202117016D0 (en)	2021-11-25	2022-01-12	Orexo Ab	New pharmaceutical device
AR127780A1 (es)	2021-11-25	2024-02-28	Orexo Ab	Nueva composición farmacéutica que comprende adrenalina

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US4464378A (en) *	1981-04-28	1984-08-07	University Of Kentucky Research Foundation	Method of administering narcotic antagonists and analgesics and novel dosage forms containing same
GB9202464D0 (en)	1992-02-05	1992-03-18	Danbiosyst Uk	Composition for nasal administration
US5866154A (en) *	1994-10-07	1999-02-02	The Dupont Merck Pharmaceutical Company	Stabilized naloxone formulations
US6608073B1 (en)	1998-10-14	2003-08-19	New Millennium Pharmaceutical Research, Inc.	Intranasal codeine for the rapid suppression of cough and rapid relief of pain
GB9908921D0 (en) *	1999-04-19	1999-06-16	Britannia Pharmaceuticals Ltd	Spray dispenser for opiod antagonists
TR200103613T2 (tr)	1999-06-16	2004-08-23	Nastech Pharmaceutical Co., Inc.	Burun içinden tatbik edilen morfini içeren farmasötik formülasyonlar ve yöntemler.
GB9924797D0 (en)	1999-10-20	1999-12-22	West Pharm Serv Drug Res Ltd	Compound
US6284765B1 (en)	2000-04-27	2001-09-04	The University Of North Texas Health Science Center At Fort Worth	(+) naloxone and epinephrine combination therapy
WO2002011778A1 (en) *	2000-05-10	2002-02-14	University Of Kentucky Research Foundation	System and method for intranasal administration of opioids
US20040115133A1 (en) *	2000-05-10	2004-06-17	Wermeling Daniel P.	Intranasal opioid compositions
EA006384B1 (ru) *	2000-07-31	2005-12-29	Нюкомед Данмарк А/С	Композиция фентанила для интраназального введения
DE10064219B9 (de)	2000-12-22	2009-02-12	Nasalis Pain Relief International Gmbh	Neue Fentanyl und/oder dessen Derivate enthaltende pharmazeutische Zusammensetzung zur nasalen Anwendung
US7666876B2 (en)	2002-03-19	2010-02-23	Vernalis (R&D) Limited	Buprenorphine formulations for intranasal delivery
EP1535615A4 (en)	2002-07-11	2010-03-31	Taiho Pharmaceutical Co Ltd	COMPOSITION FOR THE NASAL ABSORPTION
GB0300531D0 (en)	2003-01-10	2003-02-12	West Pharm Serv Drug Res Ltd	Pharmaceutical compositions
CN1575795A (zh) *	2003-06-25	2005-02-09	中国人民解放军军事医学科学院毒物药物研究所	盐酸纳洛酮鼻腔喷雾剂
GB2403711A (en) *	2003-07-07	2005-01-12	Gw Pharma Ltd	Drug dispenser with controlled access
GB0400804D0 (en)	2004-01-14	2004-02-18	Innoscience Technology Bv	Pharmaceutical compositions
CN1726915B (zh) *	2004-07-27	2013-04-24	中国人民解放军军事医学科学院毒物药物研究所	盐酸纳洛酮鼻腔给药系统或组合物及其制备方法
WO2006016530A1 (ja)	2004-08-10	2006-02-16	Translational Research, Ltd.	速効性でかつ高い吸収性を可能とする経鼻投与用組成物
KR20070083985A (ko) *	2004-11-09	2007-08-24	코닌클리케 필립스 일렉트로닉스 엔.브이.	공간 광 변조기의 배열 및 공간 광 변조기 디바이스의 생산방법
ZA200704869B (en) *	2004-12-23	2009-02-25	Roxro Pharma Inc	Therapeutic compositions for intranasal administration of ketorolac
US8911751B2 (en)	2005-10-11	2014-12-16	Yissum Research Development Company Of The Hebrew University Of Jerusalem	Compositions for nasal delivery
US20070212307A1 (en) *	2006-02-10	2007-09-13	Daniel Wermeling	Pharmaceutical Compositions Comprising an Opioid Receptor Antagonist and Methods of Using Same
RU2344822C2 (ru) *	2006-04-05	2009-01-27	Алексей Валентинович Надеждин	Способ лечения героиновой наркомании
US8337817B2 (en)	2006-12-26	2012-12-25	Shin Nippon Biomedical Laboratories, Ltd.	Preparation for transnasal application
CN101678112B (zh) *	2007-01-19	2016-08-31	哈南亚有限公司	用于递送治疗剂的方法和组合物
WO2009040595A1 (en)	2007-09-28	2009-04-02	Wockhardt Research Centre	Multi-dose pharmaceutical composition of analgesic for nasal administration
MY194947A (en) *	2011-05-13	2022-12-27	Euro Celtique Sa	Intranasal pharmaceutical dosage forms comprising naloxone
CA2875384A1 (en)	2013-12-20	2015-06-20	AntiOP, Inc.	Intranasal naloxone compositions and methods of making and using same
US9561177B2 (en)	2014-03-14	2017-02-07	Adapt Pharma Limited	Nasal drug products and methods of their use
MX365383B (es)	2014-03-14	2019-05-31	Opiant Pharmaceuticals Inc	Medicamentos de administracion nasal y metodos para su uso.
US9480644B2 (en)	2014-03-14	2016-11-01	Opiant Pharmaceuticals, Inc.	Nasal drug products and methods of their use
US10085937B2 (en)	2014-03-14	2018-10-02	Adapt Pharma Limited	Nasal drug products and methods of their use
US10617686B2 (en)	2014-07-08	2020-04-14	Hikma Pharmaceuticals Usa Inc.	Liquid naloxone spray

2012
- 2012-05-11 MY MYPI2018001495A patent/MY194947A/en unknown
- 2012-05-11 PL PL12721507T patent/PL2706982T3/pl unknown
- 2012-05-11 RU RU2016117731A patent/RU2657441C1/ru active
- 2012-05-11 MX MX2013013276A patent/MX354249B/es active IP Right Grant
- 2012-05-11 RS RS20180193A patent/RS57054B1/sr unknown
- 2012-05-11 PT PT127215077T patent/PT2706982T/pt unknown
- 2012-05-11 ES ES12721507T patent/ES2661838T5/es active Active
- 2012-05-11 DK DK12721507.7T patent/DK2706982T4/da active
- 2012-05-11 TW TW101116857A patent/TWI486161B/zh not_active IP Right Cessation
- 2012-05-11 CN CN201710310253.2A patent/CN107260672A/zh active Pending
- 2012-05-11 HR HRP20180233TT patent/HRP20180233T1/hr unknown
- 2012-05-11 US US14/084,551 patent/US20150018379A1/en not_active Abandoned
- 2012-05-11 RU RU2013155479/15A patent/RU2587051C2/ru not_active IP Right Cessation
- 2012-05-11 TR TR2018/02716T patent/TR201802716T4/tr unknown
- 2012-05-11 AT ATGM50043/2018U patent/AT16553U1/de not_active IP Right Cessation
- 2012-05-11 BR BR112013029126A patent/BR112013029126A2/pt not_active IP Right Cessation
- 2012-05-11 DE DE202012013606.2U patent/DE202012013606U1/de not_active Expired - Lifetime
- 2012-05-11 KR KR1020177001202A patent/KR101873174B1/ko active Active
- 2012-05-11 JP JP2014509762A patent/JP6110367B2/ja active Active
- 2012-05-11 SI SI201231239T patent/SI2706982T1/en unknown
- 2012-05-11 SG SG2013083886A patent/SG194927A1/en unknown
- 2012-05-11 PH PH1/2013/502313A patent/PH12013502313A1/en unknown
- 2012-05-11 LT LTEP12721507.7T patent/LT2706982T/lt unknown
- 2012-05-11 CA CA2835940A patent/CA2835940C/en active Active
- 2012-05-11 WO PCT/EP2012/058792 patent/WO2012156317A2/en not_active Ceased
- 2012-05-11 KR KR1020137032730A patent/KR101698182B1/ko active Active
- 2012-05-11 SM SM20180105T patent/SMT201800105T1/it unknown
- 2012-05-11 ME MEP-2018-35A patent/ME02958B/me unknown
- 2012-05-11 EP EP12721507.7A patent/EP2706982B2/en active Active
- 2012-05-11 AU AU2012257785A patent/AU2012257785B2/en active Active
- 2012-05-11 AR ARP120101700A patent/AR086391A1/es unknown
- 2012-05-11 NO NO12721507A patent/NO2706982T3/no unknown
- 2012-05-11 HU HUE12721507A patent/HUE036465T2/hu unknown
- 2012-05-11 CN CN201280032034.8A patent/CN103764119A/zh not_active Withdrawn
- 2012-05-11 EP EP17208976.5A patent/EP3320893A1/en not_active Withdrawn
- 2012-11-05 UA UAA201314634A patent/UA110974C2/uk unknown
2013
- 2013-11-05 ZA ZA2013/08280A patent/ZA201308280B/en unknown
- 2013-11-12 IL IL229409A patent/IL229409B/en active IP Right Grant
- 2013-12-13 CO CO13291649A patent/CO6821959A2/es not_active Application Discontinuation
2015
- 2015-01-06 US US14/590,808 patent/US20150126540A1/en not_active Abandoned
2016
- 2016-01-14 JP JP2016005172A patent/JP2016128453A/ja active Pending
- 2016-07-05 PH PH12016501342A patent/PH12016501342A1/en unknown
- 2016-07-13 AU AU2016204880A patent/AU2016204880B2/en active Active
2017
- 2017-01-27 US US15/418,138 patent/US20170231904A1/en not_active Abandoned
- 2017-05-09 US US15/590,466 patent/US20170304192A1/en not_active Abandoned
2018
- 2018-02-26 CY CY20181100228T patent/CY1120399T1/el unknown
- 2018-04-19 DK DKBA201800034U patent/DK201800034U1/da not_active Application Discontinuation
- 2018-05-09 JP JP2018090275A patent/JP2018150336A/ja active Pending
- 2018-11-15 HK HK18114591.4A patent/HK1255428A1/en unknown
2019
- 2019-08-23 US US16/549,838 patent/US11020343B2/en active Active
2021
- 2021-04-23 US US17/238,509 patent/US11806428B2/en active Active
2023
- 2023-09-19 US US18/370,116 patent/US12458591B2/en active Active
2025
- 2025-10-10 US US19/355,540 patent/US20260108456A1/en active Pending

Also Published As

Publication number	Publication date
JP2018150336A (ja)	2018-09-27
US20260108456A1 (en)	2026-04-23
EP2706982A2 (en)	2014-03-19
RU2657441C1 (ru)	2018-06-13
DK201800034U1 (da)	2018-05-25
HK1255428A1 (en)	2019-08-16
AT16553U1 (de)	2020-01-15
JP2014513683A (ja)	2014-06-05
CA2835940A1 (en)	2012-11-22
US20240082149A1 (en)	2024-03-14
US20170304192A1 (en)	2017-10-26
KR20140007482A (ko)	2014-01-17
AU2012257785A1 (en)	2013-11-28
EP2706982B1 (en)	2018-01-03
AU2016204880A1 (en)	2016-07-28
CA2835940C (en)	2020-08-04
IL229409B (en)	2020-10-29
TWI486161B (zh)	2015-06-01
TR201802716T4 (tr)	2018-03-21
KR20170010078A (ko)	2017-01-25
US20150018379A1 (en)	2015-01-15
DK2706982T4 (da)	2021-05-10
PH12013502313A1 (en)	2022-04-08
CO6821959A2 (es)	2013-12-31
ES2661838T5 (es)	2021-11-18
JP6110367B2 (ja)	2017-04-05
NO2706982T3 (pt)	2018-06-02
WO2012156317A2 (en)	2012-11-22
EP2706982B2 (en)	2021-03-10
EP3320893A1 (en)	2018-05-16
CN107260672A (zh)	2017-10-20
MX354249B (es)	2018-02-20
KR101698182B1 (ko)	2017-01-19
RS57054B1 (sr)	2018-05-31
SMT201800105T1 (it)	2018-05-02
SG194927A1 (en)	2013-12-30
MX2013013276A (es)	2014-08-07
NZ705933A (en)	2016-07-29
RU2013155479A (ru)	2015-06-20
PL2706982T3 (pl)	2018-07-31
AR086391A1 (es)	2013-12-11
US20190374464A1 (en)	2019-12-12
US20210338574A1 (en)	2021-11-04
ZA201308280B (en)	2014-07-30
MY194947A (en)	2022-12-27
SI2706982T1 (en)	2018-05-31
US12458591B2 (en)	2025-11-04
BR112013029126A2 (pt)	2017-02-07
CN103764119A (zh)	2014-04-30
AU2012257785B2 (en)	2016-04-14
DE202012013606U1 (de)	2018-04-18
AU2016204880B2 (en)	2017-11-23
US20170231904A1 (en)	2017-08-17
WO2012156317A3 (en)	2013-05-10
US20150126540A1 (en)	2015-05-07
US11020343B2 (en)	2021-06-01
UA110974C2 (uk)	2016-03-10
DK2706982T3 (en)	2018-03-12
LT2706982T (lt)	2018-05-25
NZ617442A (en)	2015-03-27
IL229409A0 (en)	2014-01-30
ES2661838T3 (es)	2018-04-04
PH12016501342B1 (en)	2018-06-11
HUE036465T2 (hu)	2018-07-30
ME02958B (me)	2018-07-20
KR101873174B1 (ko)	2018-06-29
RU2587051C2 (ru)	2016-06-10
CY1120399T1 (el)	2019-07-10
PH12016501342A1 (en)	2018-06-11
JP2016128453A (ja)	2016-07-14
US11806428B2 (en)	2023-11-07
TW201311244A (zh)	2013-03-16
HRP20180233T1 (hr)	2018-06-01

Publication	Publication Date	Title
PT2706982T (pt)	2018-03-08	Formas farmacêutica de administração por via nasal contendo naloxona
PL2817052T3 (pl)	2018-01-31	Urządzenia do podawania donosowego
CO6852076A2 (es)	2014-01-30	Composiciones farmacéuticas inhalables
HUE057510T2 (hu)	2022-05-28	Félplasztikus gyógyszerészeti dózisegységek elõállítása
BR112013018828A2 (pt)	2017-02-21	sistemas de distribuição de droga
EP2739341A4 (en)	2015-04-22	Microfluidic release agents
EP2771043A4 (en)	2015-04-29	ACTIVE RELEASE PROCEDURE
DK2768559T3 (da)	2023-09-18	Lægemiddelindgivelsesanordning
EP2787977A4 (en)	2015-05-06	LIPOSOMAL ACTIVE INVERTING
EP2720699A4 (en)	2015-04-29	ADMINISTRATION OF BENZODIAZEPINE
EP2748685A4 (en)	2015-05-20	PORTABLE MEDICINAL DISPENSER
EP2773302A4 (en)	2015-03-25	NASAL DILATOR
IL230838A0 (en)	2014-03-31	Pharmaceutical compositions
DK2740504T3 (da)	2020-11-16	Lægemiddelfremføringsanordning
EP2702989A4 (en)	2014-12-31	STABLE PHARMACEUTICAL COMPOSITION
CO6940426A2 (es)	2014-05-09	Formulaciones farmacéuticas
HUE049942T2 (hu)	2020-11-30	Inozitolt tartalmazó gyógyszerészeti formuláció
IL231622B (en)	2018-10-31	Pharmaceutical composition for treatment of cachexia
HRP20181316T1 (hr)	2018-10-19	Tehnologija isporuke lijeka
EP2679264A4 (en)	2014-12-31	Gas mist inhaler
DK3143998T3 (da)	2019-06-17	Inhalerbart lægemiddel omfattende tiotropium
HRP20180567T1 (hr)	2018-05-18	Farmaceutski pripravak omeprazola
BR112014015885A8 (pt)	2017-07-04	preparação farmacêutica
BR112014009319A2 (pt)	2017-05-30	compostos farmacêuticos
EP2769718A4 (en)	2015-07-01	MEDICAL COMPOSITION