PT2809681T - Anticorpos anti-asic1 e suas utilizações - Google Patents

Anticorpos anti-asic1 e suas utilizações

Info

Publication number: PT2809681T
Authority: PT; Portugal
Prior art keywords: asic1 antibodies; asic1; antibodies
Prior art date: 2012-01-31

Application number

PT13702876T

Other languages

English (en)

Inventor

Macdonald Lynn

L Lacroix-Fralish Michael

Gao Min

R Morra Marc

M Alessandri-Haber Nicole

Original Assignee

Regeneron Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2012-01-31

Filing date

2013-01-30

Publication date

2019-02-18

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47666522&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2809681(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2013-01-30 Application filed by Regeneron Pharma filed Critical Regeneron Pharma

2019-02-18 Publication of PT2809681T publication Critical patent/PT2809681T/pt

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Immunology (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Pain & Pain Management (AREA)
Engineering & Computer Science (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Rheumatology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

PT13702876T 2012-01-31 2013-01-30 Anticorpos anti-asic1 e suas utilizações PT2809681T (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date
US201261592837P	2012-01-31	2012-01-31
US201261644038P	2012-05-08	2012-05-08
US201261692925P	2012-08-24	2012-08-24

Publications (1)

Publication Number	Publication Date
PT2809681T true PT2809681T (pt)	2019-02-18

Family

ID=47666522

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
PT13702876T PT2809681T (pt)	2012-01-31	2013-01-30	Anticorpos anti-asic1 e suas utilizações
PT182018234T PT3453723T (pt)	2012-01-31	2013-01-30	Anticorpos anti-asic1 e suas utilizações

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
PT182018234T PT3453723T (pt)	2012-01-31	2013-01-30	Anticorpos anti-asic1 e suas utilizações

Country Status (33)

Country	Link
US (3)	US9150648B2 (pt)
EP (2)	EP3453723B1 (pt)
JP (1)	JP6302844B2 (pt)
KR (1)	KR102111941B1 (pt)
CN (1)	CN104093738B (pt)
AR (1)	AR089852A1 (pt)
AU (1)	AU2013215254B2 (pt)
CA (1)	CA2862332C (pt)
CL (1)	CL2014002019A1 (pt)
CO (1)	CO7020877A2 (pt)
CY (2)	CY1121368T1 (pt)
DK (2)	DK3453723T3 (pt)
EA (1)	EA028647B1 (pt)
ES (2)	ES2886123T3 (pt)
HR (2)	HRP20190358T1 (pt)
HU (2)	HUE056335T2 (pt)
IL (2)	IL233410A0 (pt)
IN (1)	IN2014CN04645A (pt)
JO (1)	JO3547B1 (pt)
LT (2)	LT3453723T (pt)
MX (1)	MX358518B (pt)
MY (1)	MY168748A (pt)
NZ (1)	NZ626242A (pt)
PH (1)	PH12014501613A1 (pt)
PL (2)	PL2809681T3 (pt)
PT (2)	PT2809681T (pt)
RS (2)	RS62454B1 (pt)
SG (1)	SG11201403222UA (pt)
SI (2)	SI3453723T1 (pt)
SM (1)	SMT202100628T1 (pt)
TW (1)	TWI591073B (pt)
UY (1)	UY34603A (pt)
WO (1)	WO2013116296A1 (pt)

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AU2015247742A1 (en)	2014-04-15	2016-11-24	Sorrento Therapeutics, Inc.	Antigen binding proteins that bind WISP1
IL318433A (en)	2014-05-16	2025-03-01	Ablynx Nv	Improved immunoglobulin variable complexes
SG11201609162SA (en)	2014-05-16	2016-12-29	Ablynx Nv	Improved immunoglobulin variable domains
CN105233286B (zh) *	2015-09-10	2018-10-30	上海交通大学医学院	含酸敏感离子通道调控剂的制剂及其在治疗瘙痒中的用途
CN105713089B (zh) *	2016-02-26	2019-08-06	上海科技大学	一种特异性抑制酸敏感离子通道i型的全人抗体
WO2018085441A1 (en) *	2016-11-01	2018-05-11	Berg Llc	Filamin b binding proteins and uses thereof
BR112020015112A2 (pt) *	2018-01-26	2021-04-06	Regeneron Pharmaceuticals, Inc.	Anticorpos anti-tmprss2 e fragmentos que ligam antígenos
CN114729034B (zh) *	2019-06-04	2024-01-12	上海科技大学	亲和力成熟的抗ASIC1a抗体
BR112022000216A2 (pt) *	2019-07-11	2022-05-17	Memorial Sloan Kettering Cancer Center	Anticorpos direcionados a dll3 e usos dos mesmos
WO2021012176A1 (en) *	2019-07-23	2021-01-28	Shanghaitech University	Asic1 channel antagonist antibody
JP7796008B2 (ja) *	2019-09-13	2026-01-08	メモリアルスローンケタリングキャンサーセンター	抗ｃｄ３７１抗体およびその使用
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EP4396224A4 (en) *	2021-09-02	2025-11-12	Memorial Sloan Kettering Cancer Center	Anti-DLL3 Antibodies and Their Uses
JP2024083709A (ja) *	2022-12-12	2024-06-24	ａｒｔｉｅｎｃｅ株式会社	コート剤、シートおよび成形体
CN119331085B (zh) *	2024-10-16	2025-03-14	中国科学院合肥物质科学研究院	沙贝冠状病毒广谱中和抗体及其应用

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US6287859B1 (en)	1998-08-05	2001-09-11	Centre National De La Recherche	Identification, functional expression and chromosal localization of a sustained human proton-gated cation channel
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US9371383B2 (en)	2012-01-31	2016-06-21	Regeneron Pharmaceuticals, Inc.	Anti-ASIC1 antibodies and uses thereof

2013
- 2013-01-30 AU AU2013215254A patent/AU2013215254B2/en active Active
- 2013-01-30 MX MX2014008541A patent/MX358518B/es active IP Right Grant
- 2013-01-30 SI SI201331923T patent/SI3453723T1/sl unknown
- 2013-01-30 ES ES18201823T patent/ES2886123T3/es active Active
- 2013-01-30 DK DK18201823.4T patent/DK3453723T3/da active
- 2013-01-30 RS RS20211284A patent/RS62454B1/sr unknown
- 2013-01-30 LT LTEP18201823.4T patent/LT3453723T/lt unknown
- 2013-01-30 JO JOP/2013/0036A patent/JO3547B1/ar active
- 2013-01-30 NZ NZ626242A patent/NZ626242A/en unknown
- 2013-01-30 LT LTEP13702876.7T patent/LT2809681T/lt unknown
- 2013-01-30 WO PCT/US2013/023784 patent/WO2013116296A1/en not_active Ceased
- 2013-01-30 HR HRP20190358TT patent/HRP20190358T1/hr unknown
- 2013-01-30 TW TW102103458A patent/TWI591073B/zh active
- 2013-01-30 RS RS20190287A patent/RS58439B1/sr unknown
- 2013-01-30 PL PL13702876T patent/PL2809681T3/pl unknown
- 2013-01-30 ES ES13702876T patent/ES2707599T3/es active Active
- 2013-01-30 PL PL18201823T patent/PL3453723T3/pl unknown
- 2013-01-30 JP JP2014554950A patent/JP6302844B2/ja active Active
- 2013-01-30 CN CN201380007553.3A patent/CN104093738B/zh active Active
- 2013-01-30 EP EP18201823.4A patent/EP3453723B1/en active Active
- 2013-01-30 HR HRP20211541TT patent/HRP20211541T1/hr unknown
- 2013-01-30 IN IN4645CHN2014 patent/IN2014CN04645A/en unknown
- 2013-01-30 AR ARP130100280 patent/AR089852A1/es active IP Right Grant
- 2013-01-30 HU HUE18201823A patent/HUE056335T2/hu unknown
- 2013-01-30 EP EP13702876.7A patent/EP2809681B1/en active Active
- 2013-01-30 SM SM20210628T patent/SMT202100628T1/it unknown
- 2013-01-30 SI SI201331343T patent/SI2809681T1/sl unknown
- 2013-01-30 DK DK13702876.7T patent/DK2809681T3/en active
- 2013-01-30 PT PT13702876T patent/PT2809681T/pt unknown
- 2013-01-30 MY MYPI2014001721A patent/MY168748A/en unknown
- 2013-01-30 HU HUE13702876A patent/HUE042531T2/hu unknown
- 2013-01-30 SG SG11201403222UA patent/SG11201403222UA/en unknown
- 2013-01-30 PT PT182018234T patent/PT3453723T/pt unknown
- 2013-01-30 CA CA2862332A patent/CA2862332C/en active Active
- 2013-01-30 EA EA201491452A patent/EA028647B1/ru not_active IP Right Cessation
- 2013-01-30 US US13/753,836 patent/US9150648B2/en active Active
- 2013-01-30 KR KR1020147020682A patent/KR102111941B1/ko active Active
- 2013-01-31 UY UY34603A patent/UY34603A/es not_active Application Discontinuation
2014
- 2014-06-26 IL IL233410A patent/IL233410A0/en unknown
- 2014-07-11 PH PH12014501613A patent/PH12014501613A1/en unknown
- 2014-07-25 CO CO14162499A patent/CO7020877A2/es unknown
- 2014-07-30 CL CL2014002019A patent/CL2014002019A1/es unknown
2015
- 2015-09-09 US US14/848,452 patent/US20160002332A1/en not_active Abandoned
2017
- 2017-09-11 IL IL254416A patent/IL254416B/en active IP Right Grant
- 2017-09-28 US US15/719,220 patent/US10513557B2/en active Active
2019
- 2019-02-27 CY CY20191100246T patent/CY1121368T1/el unknown
2021
- 2021-11-09 CY CY20211100968T patent/CY1124778T1/el unknown

Also Published As

Publication number	Publication date
CA2862332A1 (en)	2013-08-08
UY34603A (es)	2013-07-31
CN104093738B (zh)	2018-05-18
RS62454B1 (sr)	2021-11-30
HUE042531T2 (hu)	2019-07-29
EP3453723B1 (en)	2021-08-11
EA201491452A1 (ru)	2014-11-28
PH12014501613B1 (en)	2014-10-13
SMT202100628T1 (it)	2022-01-10
NZ626242A (en)	2017-02-24
EP3453723A2 (en)	2019-03-13
MY168748A (en)	2018-11-30
KR20140125363A (ko)	2014-10-28
JO3547B1 (ar)	2020-07-05
AR089852A1 (es)	2014-09-24
MX2014008541A (es)	2014-10-24
TW201335182A (zh)	2013-09-01
TWI591073B (zh)	2017-07-11
PL2809681T3 (pl)	2019-05-31
HUE056335T2 (hu)	2022-02-28
DK2809681T3 (en)	2019-03-11
RS58439B1 (sr)	2019-04-30
PT3453723T (pt)	2021-09-07
IN2014CN04645A (pt)	2015-09-18
ES2707599T3 (es)	2019-04-04
IL233410A0 (en)	2014-08-31
AU2013215254B2 (en)	2017-08-31
HRP20211541T1 (hr)	2021-12-24
PH12014501613A1 (en)	2014-10-13
SI2809681T1 (sl)	2019-04-30
JP6302844B2 (ja)	2018-03-28
CY1121368T1 (el)	2020-05-29
KR102111941B1 (ko)	2020-05-18
LT3453723T (lt)	2021-09-10
CO7020877A2 (es)	2014-08-11
EA028647B1 (ru)	2017-12-29
IL254416A0 (en)	2017-11-30
PL3453723T3 (pl)	2022-01-03
US10513557B2 (en)	2019-12-24
US20180222976A1 (en)	2018-08-09
CL2014002019A1 (es)	2015-01-16
WO2013116296A1 (en)	2013-08-08
AU2013215254A1 (en)	2014-07-03
EP2809681B1 (en)	2018-12-05
IL254416B (en)	2018-03-29
JP2015508063A (ja)	2015-03-16
SI3453723T1 (sl)	2021-11-30
CY1124778T1 (el)	2022-11-25
HRP20190358T1 (hr)	2019-04-05
CN104093738A (zh)	2014-10-08
DK3453723T3 (da)	2021-09-13
EP3453723A3 (en)	2019-04-10
MX358518B (es)	2018-08-24
US20160002332A1 (en)	2016-01-07
CA2862332C (en)	2021-05-18
LT2809681T (lt)	2019-02-11
EP2809681A1 (en)	2014-12-10
US9150648B2 (en)	2015-10-06
SG11201403222UA (en)	2014-07-30
HK1199269A1 (en)	2015-06-26
ES2886123T3 (es)	2021-12-16
US20130195878A1 (en)	2013-08-01
BR112014018651A2 (pt)	2017-07-04

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