PT2877599T - Métodos e composições para determinar a resistência à terapia de recetor de androgénio - Google Patents

Métodos e composições para determinar a resistência à terapia de recetor de androgénio

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Publication number
PT2877599T
PT2877599T PT137459731T PT13745973T PT2877599T PT 2877599 T PT2877599 T PT 2877599T PT 137459731 T PT137459731 T PT 137459731T PT 13745973 T PT13745973 T PT 13745973T PT 2877599 T PT2877599 T PT 2877599T
Authority
PT
Portugal
Prior art keywords
therapy
compositions
methods
determine resistance
androgen
Prior art date
Application number
PT137459731T
Other languages
English (en)
Original Assignee
Aragon Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aragon Pharmaceuticals Inc filed Critical Aragon Pharmaceuticals Inc
Publication of PT2877599T publication Critical patent/PT2877599T/pt

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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C07K16/2869—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
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PT137459731T 2012-07-27 2013-07-26 Métodos e composições para determinar a resistência à terapia de recetor de androgénio PT2877599T (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261676842P 2012-07-27 2012-07-27
US201361783763P 2013-03-14 2013-03-14
US201361829123P 2013-05-30 2013-05-30

Publications (1)

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PT2877599T true PT2877599T (pt) 2020-01-24

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PT137459731T PT2877599T (pt) 2012-07-27 2013-07-26 Métodos e composições para determinar a resistência à terapia de recetor de androgénio

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US (2) US9617602B2 (pt)
EP (2) EP2877599B1 (pt)
JP (3) JP6297556B2 (pt)
KR (2) KR20210012064A (pt)
CN (3) CN104685072A (pt)
AU (3) AU2013295543B2 (pt)
BR (2) BR112015001801A2 (pt)
CA (1) CA2879926A1 (pt)
CL (1) CL2015000194A1 (pt)
CO (1) CO7280477A2 (pt)
CR (1) CR20150022A (pt)
CY (1) CY1122651T1 (pt)
DK (1) DK2877599T3 (pt)
EA (2) EA029563B1 (pt)
EC (1) ECSP15007420A (pt)
ES (1) ES2764381T3 (pt)
GT (1) GT201500019A (pt)
HR (1) HRP20192342T1 (pt)
HU (1) HUE047781T2 (pt)
IL (2) IL236844B (pt)
LT (1) LT2877599T (pt)
MX (2) MX370507B (pt)
NI (1) NI201500004A (pt)
NZ (4) NZ704487A (pt)
PE (3) PE20190574A1 (pt)
PH (2) PH12015500175A1 (pt)
PL (1) PL2877599T3 (pt)
PT (1) PT2877599T (pt)
RS (1) RS59812B1 (pt)
SG (2) SG10201703254VA (pt)
SI (1) SI2877599T1 (pt)
SM (1) SMT201900735T1 (pt)
UA (1) UA118178C2 (pt)
WO (1) WO2014018926A1 (pt)

Families Citing this family (32)

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Publication number Priority date Publication date Assignee Title
EP3062106B1 (en) 2008-04-16 2020-11-11 The Johns Hopkins University Method for determining androgen receptor variants in prostate cancer
EP2791128A4 (en) 2011-12-16 2015-04-22 Olema Pharmaceuticals Inc NOVEL BENZOPYRAN COMPOUNDS, COMPOSITIONS AND USES THEREOF
US10202653B2 (en) 2012-04-20 2019-02-12 Cepheid Compositions and methods for detecting markers associated with bladder cancer
EP2912194B1 (en) 2012-10-26 2019-05-08 Memorial Sloan-Kettering Cancer Center Androgen receptor variants and methods for making and using
EP3327144B1 (en) * 2013-02-25 2020-03-25 Novartis AG Novel androgen receptor mutation
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