PT3256570T - Herpesvírus redirecionado com fusão de glicoproteína h - Google Patents
Herpesvírus redirecionado com fusão de glicoproteína hInfo
- Publication number
- PT3256570T PT3256570T PT167045897T PT16704589T PT3256570T PT 3256570 T PT3256570 T PT 3256570T PT 167045897 T PT167045897 T PT 167045897T PT 16704589 T PT16704589 T PT 16704589T PT 3256570 T PT3256570 T PT 3256570T
- Authority
- PT
- Portugal
- Prior art keywords
- herpesvirus
- redirected
- glycoprotein
- fusion
- herpesvirus redirected
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- C12N15/869—Herpesviral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16032—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16632—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15425012 | 2015-02-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3256570T true PT3256570T (pt) | 2021-06-18 |
Family
ID=52814952
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT167045897T PT3256570T (pt) | 2015-02-11 | 2016-02-11 | Herpesvírus redirecionado com fusão de glicoproteína h |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US10421979B2 (pt) |
| EP (1) | EP3256570B1 (pt) |
| JP (1) | JP6751721B2 (pt) |
| CN (1) | CN107406834B (pt) |
| AU (1) | AU2016217906B2 (pt) |
| CA (1) | CA2974868C (pt) |
| DK (1) | DK3256570T3 (pt) |
| ES (1) | ES2874584T3 (pt) |
| HU (1) | HUE054563T2 (pt) |
| PL (1) | PL3256570T3 (pt) |
| PT (1) | PT3256570T (pt) |
| RU (1) | RU2732120C2 (pt) |
| WO (1) | WO2016128497A1 (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3235908A1 (en) * | 2016-04-21 | 2017-10-25 | Ecole Normale Superieure De Lyon | Methods for selectively modulating the activity of distinct subtypes of cells |
| JP7190166B2 (ja) | 2016-06-09 | 2022-12-15 | アルマ・マテール・ストゥディオルム・ウニベルシータ・ディ・ボローニャ | 改変糖タンパク質ｄを有するヘルペスウイルス |
| WO2017211941A1 (en) | 2016-06-09 | 2017-12-14 | Alma Mater Studiorum Universita Di Bologna | Herpesvirus with modified glycoprotein b |
| JP7072807B2 (ja) | 2016-06-09 | 2022-05-23 | アルマ・マテール・ストゥディオルム・ウニベルシータ・ディ・ボローニャ | 細胞内増殖のための改変糖タンパク質ｈを有するヘルペスウイルス |
| WO2019147869A2 (en) * | 2018-01-24 | 2019-08-01 | Virogin Biotech Canada Ltd | Recombinant viral vaccines |
| EP3810164A4 (en) * | 2018-05-31 | 2022-03-09 | University of Pittsburgh - of the Commonwealth System of Higher Education | ANTIGENIC DISGUISED ONCOLYTIC VIRUSES |
| CN108913665B (zh) * | 2018-07-26 | 2021-06-22 | 江苏省农业科学院 | 一种分泌抗CpHV-1单克隆抗体的杂交瘤细胞株及其应用 |
| KR20210023751A (ko) * | 2019-08-22 | 2021-03-04 | 주식회사 젠셀메드 | 암세포 표적화 영역과 hvem의 세포외 도메인의 융합 단백질을 발현할 수 있는 발현 카세트를 가지는 재조합 헤르페스 심플렉스 바이러스 및 그 용도 |
| JP7460850B2 (ja) * | 2020-06-12 | 2024-04-02 | ジェンセルメッド インコーポレイテッド | 多重標的化組換えヘルペスシンプルレックスウイルス及びその用途 |
| CN116462753B (zh) * | 2023-05-16 | 2025-12-12 | 广西壮族自治区兽医研究所 | H9N2亚型AIV多拷贝M2e蛋白单克隆抗体、细胞系及其制备方法和应用 |
| TW202521570A (zh) * | 2023-08-25 | 2025-06-01 | 大陸商勃林格殷格翰動物保健（中國）有限公司 | 用於禽類疫苗的新型ｄｅｖ載體 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0714578D0 (en) * | 2007-07-26 | 2007-09-05 | Crusade Lab Ltd | Viruses |
| BRPI0816134A2 (pt) * | 2007-08-28 | 2015-07-28 | Université de Liège | Herpesvírus, sequência de dna, vetor, célula, vírus, método para produção de partículas infecciosas, partículas infecciosas, vacina, uso de herpesvírus ou da sequência de dna ou do vetor ou das partículas infecciosas, e, método para o tratamento preventivo e/ou terapêutico de uma doença. |
| EP2700405B1 (en) * | 2008-05-29 | 2018-04-04 | Alma Mater Studiorum -Universita' di Bologna | Herpes simplex virus (HSV) with modified tropism, uses and process of preparation thereof |
| WO2011106607A2 (en) * | 2010-02-26 | 2011-09-01 | Juvaris Biotherapeutics, Inc. | Subunit vaccines for herpes viruses and methods of use |
| CN106068326B (zh) * | 2013-10-28 | 2021-06-18 | 联邦高等教育系统-匹兹堡大学 | 溶瘤性hsv载体 |
-
2016
- 2016-02-11 DK DK16704589.7T patent/DK3256570T3/da active
- 2016-02-11 PT PT167045897T patent/PT3256570T/pt unknown
- 2016-02-11 ES ES16704589T patent/ES2874584T3/es active Active
- 2016-02-11 RU RU2017127024A patent/RU2732120C2/ru active
- 2016-02-11 CN CN201680009622.8A patent/CN107406834B/zh not_active Expired - Fee Related
- 2016-02-11 JP JP2017542375A patent/JP6751721B2/ja active Active
- 2016-02-11 US US15/548,731 patent/US10421979B2/en active Active
- 2016-02-11 AU AU2016217906A patent/AU2016217906B2/en not_active Expired - Fee Related
- 2016-02-11 WO PCT/EP2016/052879 patent/WO2016128497A1/en not_active Ceased
- 2016-02-11 HU HUE16704589A patent/HUE054563T2/hu unknown
- 2016-02-11 PL PL16704589T patent/PL3256570T3/pl unknown
- 2016-02-11 EP EP16704589.7A patent/EP3256570B1/en active Active
- 2016-02-11 CA CA2974868A patent/CA2974868C/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2016128497A1 (en) | 2016-08-18 |
| ES2874584T3 (es) | 2021-11-05 |
| PL3256570T3 (pl) | 2021-11-29 |
| RU2017127024A (ru) | 2019-03-12 |
| RU2732120C2 (ru) | 2020-09-11 |
| HUE054563T2 (hu) | 2021-09-28 |
| EP3256570A1 (en) | 2017-12-20 |
| CN107406834B (zh) | 2021-03-16 |
| AU2016217906B2 (en) | 2021-09-02 |
| CN107406834A (zh) | 2017-11-28 |
| RU2017127024A3 (pt) | 2019-09-03 |
| JP6751721B2 (ja) | 2020-09-09 |
| DK3256570T3 (da) | 2021-06-14 |
| US10421979B2 (en) | 2019-09-24 |
| CA2974868C (en) | 2024-09-10 |
| EP3256570B1 (en) | 2021-03-31 |
| CA2974868A1 (en) | 2016-08-18 |
| JP2018512115A (ja) | 2018-05-17 |
| US20180002723A1 (en) | 2018-01-04 |
| AU2016217906A1 (en) | 2017-08-10 |
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