PT3660073T - Poli-(lactídeo-co-glicolídeo) de libertação imediata reduzida - Google Patents

Poli-(lactídeo-co-glicolídeo) de libertação imediata reduzida

Info

Publication number: PT3660073T
Authority: PT; Portugal
Prior art keywords: polymers; methods; low; burst; produce
Prior art date: 2007-02-15

Application number

PT192030716T

Other languages

English (en)

Original Assignee

Tolmar International Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-02-15

Filing date

2008-02-13

Publication date

2023-08-31

2008-02-13 Application filed by Tolmar International Ltd filed Critical Tolmar International Ltd

2023-08-31 Publication of PT3660073T publication Critical patent/PT3660073T/pt

Links

229920000642 polymer Polymers 0.000 title 2

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
- C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
- C08G63/08—Lactones or lactides
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/88—Post-polymerisation treatment
- C08G63/90—Purification; Drying
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Endocrinology (AREA)
Immunology (AREA)
Polymers & Plastics (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Reproductive Health (AREA)
Gastroenterology & Hepatology (AREA)
Oncology (AREA)
Ophthalmology & Optometry (AREA)
Communicable Diseases (AREA)
Pain & Pain Management (AREA)
Inorganic Chemistry (AREA)
Dermatology (AREA)
Gynecology & Obstetrics (AREA)
Rheumatology (AREA)
Neurology (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Psychiatry (AREA)
Physical Education & Sports Medicine (AREA)
Virology (AREA)
Tropical Medicine & Parasitology (AREA)
Pregnancy & Childbirth (AREA)

PT192030716T 2007-02-15 2008-02-13 Poli-(lactídeo-co-glicolídeo) de libertação imediata reduzida PT3660073T (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US90143507P	2007-02-15	2007-02-15

Publications (1)

Publication Number	Publication Date
PT3660073T true PT3660073T (pt)	2023-08-31

Family

ID=39504385

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
PT151852183T PT3202814T (pt)	2007-02-15	2008-02-13	Poli-(lactido/glicolido) de libertação imediata reduzida e métodos de produção de polímeros
PT192030716T PT3660073T (pt)	2007-02-15	2008-02-13	Poli-(lactídeo-co-glicolídeo) de libertação imediata reduzida
PT87255113T PT2115029E (pt)	2007-02-15	2008-02-13	Poli-(lactido/glicolido) de efeito de libertação imediata reduzido e métodos de produção de polímeros

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
PT151852183T PT3202814T (pt)	2007-02-15	2008-02-13	Poli-(lactido/glicolido) de libertação imediata reduzida e métodos de produção de polímeros

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
PT87255113T PT2115029E (pt)	2007-02-15	2008-02-13	Poli-(lactido/glicolido) de efeito de libertação imediata reduzido e métodos de produção de polímeros

Country Status (15)

Country	Link
US (7)	US9187593B2 (pt)
EP (3)	EP3202814B1 (pt)
JP (3)	JP5342459B2 (pt)
CA (1)	CA2678350C (pt)
CY (2)	CY1116785T1 (pt)
DK (3)	DK3660073T3 (pt)
ES (3)	ES2550014T3 (pt)
FI (1)	FI3660073T3 (pt)
HR (3)	HRP20231117T3 (pt)
HU (3)	HUE047775T2 (pt)
LT (2)	LT3202814T (pt)
PL (3)	PL3202814T3 (pt)
PT (3)	PT3202814T (pt)
SI (3)	SI3660073T1 (pt)
WO (1)	WO2008100532A1 (pt)

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AU2007207618B2 (en)	2006-01-18	2011-03-24	Foresee Pharmaceuticals Co., Ltd.	Pharmaceutical compositions with enhanced stability
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BRPI0811319A2 (pt) *	2007-05-25	2015-02-10	Tolmar Therapeutics Inc	Composição fluida, método de formação de uma composição fluida, implante biodegrádavel formado in situ, método de formação de um implante biodegradável in situ, kit, implante e método de trataento
AU2009255675B2 (en)	2008-06-03	2014-10-09	Tolmar Therapeutics, Inc.	Controlled release copolymer formulation with improved release kinetics
US10335366B2 (en)	2010-05-31	2019-07-02	Laboratorios Farmacéuticos Rovi, S.A.	Risperidone or paliperidone implant formulation
US10350159B2 (en)	2010-05-31	2019-07-16	Laboratories Farmacéuticos Rovi, S.A.	Paliperidone implant formulation
US10285936B2 (en)	2010-05-31	2019-05-14	Laboratorios Farmacéuticos Rovi, S.A.	Injectable composition with aromatase inhibitor
SI2394663T1 (sl)	2010-05-31	2022-02-28	Laboratorios Farmaceuticos Rovi, S.A.	Sestave za injicirane biološko razgradljive vsadke in situ
US10463607B2 (en)	2010-05-31	2019-11-05	Laboratorios Farmaceutics Rofi S.A.	Antipsychotic Injectable Depot Composition
ES2589106T3 (es)	2010-05-31	2016-11-10	Laboratorios Farmaceuticos Rovi, S.A.	Composición inyectable antipsicótica de liberación controlada
US10881605B2 (en)	2010-05-31	2021-01-05	Laboratorios Farmaceuticos Rovi, S.A.	Methods for the preparation of injectable depot compositions
US9272044B2 (en)	2010-06-08	2016-03-01	Indivior Uk Limited	Injectable flowable composition buprenorphine
GB2513267B (en)	2010-06-08	2015-03-18	Rb Pharmaceuticals Ltd	Injectable flowable composition comprising buprenorphine
GB2481017B (en)	2010-06-08	2015-01-07	Rb Pharmaceuticals Ltd	Microparticle buprenorphine suspension
CN103421172B (zh) *	2012-05-23	2016-01-20	上海现代药物制剂工程研究中心有限公司	一种生物可降解聚酯的纯化工艺
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EP2986278A1 (en)	2013-03-11	2016-02-24	DURECT Corporation	Injectable controlled release composition comprising high viscosity liquid carrier
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US20160106804A1 (en) *	2014-10-15	2016-04-21	Yuhua Li	Pharmaceutical composition with improved stability
NZ731309A (en)	2014-11-07	2022-02-25	Indivior Uk Ltd	Buprenorphine dosing regimens
WO2017062770A1 (en)	2015-10-08	2017-04-13	Silverberg Noah	Punctal plug and bioadhesives
US10646484B2 (en)	2017-06-16	2020-05-12	Indivior Uk Limited	Methods to treat opioid use disorder
CN108498456B (zh) *	2018-05-16	2021-01-01	丽珠医药集团股份有限公司	一种阿立哌唑缓释微球及其制备方法
PE20210047A1 (es)	2018-06-12	2021-01-08	Farm Rovi Lab Sa	Composicion inyectable
EP3975990A1 (en) *	2019-05-27	2022-04-06	Tolmar International Limited	Leuprolide acetate compositions and methods of using the same to treat breast cancer
WO2021158968A1 (en)	2020-02-06	2021-08-12	Ocular Therapeutix, Inc.	Compositions and methods for treating ocular diseases
CA3177005A1 (en)	2020-04-27	2021-11-04	Michael Goldstein	Methods of treating allergic conjunctivitis
BR112023005807A2 (pt)	2020-09-30	2023-05-02	Tolmar International Ltd	Sistema de liberação de polímero biodegradável para liberação prolongada de testosterona
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US12594236B2 (en)	2021-07-16	2026-04-07	Laboratorios Farmaceuticos Rovi, S.A.	Method of treating acute exacerbation of schizophrenia with long-acting injectable depot composition
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2008
- 2008-02-13 DK DK19203071.6T patent/DK3660073T3/da active
- 2008-02-13 HU HUE15185218A patent/HUE047775T2/hu unknown
- 2008-02-13 SI SI200832213T patent/SI3660073T1/sl unknown
- 2008-02-13 WO PCT/US2008/001887 patent/WO2008100532A1/en not_active Ceased
- 2008-02-13 SI SI200831512T patent/SI2115029T1/sl unknown
- 2008-02-13 HR HRP20231117TT patent/HRP20231117T3/hr unknown
- 2008-02-13 CA CA2678350A patent/CA2678350C/en not_active Expired - Fee Related
- 2008-02-13 LT LT15185218T patent/LT3202814T/lt unknown
- 2008-02-13 FI FIEP19203071.6T patent/FI3660073T3/fi active
- 2008-02-13 EP EP15185218.3A patent/EP3202814B1/en active Active
- 2008-02-13 ES ES08725511.3T patent/ES2550014T3/es active Active
- 2008-02-13 PT PT151852183T patent/PT3202814T/pt unknown
- 2008-02-13 PT PT192030716T patent/PT3660073T/pt unknown
- 2008-02-13 PL PL15185218T patent/PL3202814T3/pl unknown
- 2008-02-13 SI SI200832098T patent/SI3202814T1/sl unknown
- 2008-02-13 DK DK08725511.3T patent/DK2115029T3/en active
- 2008-02-13 DK DK15185218T patent/DK3202814T3/da active
- 2008-02-13 US US12/527,377 patent/US9187593B2/en not_active Expired - Fee Related
- 2008-02-13 JP JP2009550095A patent/JP5342459B2/ja active Active
- 2008-02-13 ES ES19203071T patent/ES2956244T3/es active Active
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Publication number	Publication date
US20100292195A1 (en)	2010-11-18
ES2550014T3 (es)	2015-11-03
CY1122304T1 (el)	2021-01-27
FI3660073T3 (fi)	2023-09-11
JP5848290B2 (ja)	2016-01-27
EP3202814A1 (en)	2017-08-09
US9655970B2 (en)	2017-05-23
WO2008100532A1 (en)	2008-08-21
US11147880B2 (en)	2021-10-19
EP2115029B1 (en)	2015-09-16
CY1116785T1 (el)	2017-03-15
EP3660073B1 (en)	2023-07-12
LT3660073T (lt)	2023-10-10
US20170216395A1 (en)	2017-08-03
PT2115029E (pt)	2015-10-26
HUE025842T2 (en)	2016-04-28
US20180311305A1 (en)	2018-11-01
JP2013224339A (ja)	2013-10-31
PT3202814T (pt)	2019-11-26
PL3202814T3 (pl)	2020-01-31
PL3660073T3 (pl)	2023-12-27
EP3202814B1 (en)	2019-10-16
US20220202941A1 (en)	2022-06-30
JP2010519218A (ja)	2010-06-03
CA2678350A1 (en)	2008-08-21
US20190209643A1 (en)	2019-07-11
JP2015127351A (ja)	2015-07-09
EP2115029A1 (en)	2009-11-11
CA2678350C (en)	2015-11-17
US10206970B2 (en)	2019-02-19
SI3202814T1 (sl)	2019-12-31
US9561282B2 (en)	2017-02-07
DK3202814T3 (da)	2019-11-25
SI2115029T1 (sl)	2016-01-29
PL2115029T3 (pl)	2016-01-29
HK1138303A1 (en)	2010-08-20
DK2115029T3 (en)	2015-10-05
DK3660073T3 (da)	2023-09-18
US20160106847A1 (en)	2016-04-21
HRP20192055T1 (hr)	2020-02-21
SI3660073T1 (sl)	2023-10-30
US20170095560A1 (en)	2017-04-06
US9187593B2 (en)	2015-11-17
HRP20231117T3 (hr)	2023-12-22
HUE063170T2 (hu)	2024-01-28
ES2956244T3 (es)	2023-12-15
JP6195587B2 (ja)	2017-09-13
US11717572B2 (en)	2023-08-08
JP5342459B2 (ja)	2013-11-13
ES2755374T3 (es)	2020-04-22
LT3202814T (lt)	2019-12-10
EP3660073A1 (en)	2020-06-03
US9974824B2 (en)	2018-05-22
HRP20150997T1 (hr)	2015-12-18
HUE047775T2 (hu)	2020-05-28

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