PT4069231T - Combinações de masupirdina com donepezilo ou memantina para tratamento de sintomas comportamentais e psicológicos em pacientes com demência - Google Patents

Combinações de masupirdina com donepezilo ou memantina para tratamento de sintomas comportamentais e psicológicos em pacientes com demência

Info

Publication number
PT4069231T
PT4069231T PT208286740T PT20828674T PT4069231T PT 4069231 T PT4069231 T PT 4069231T PT 208286740 T PT208286740 T PT 208286740T PT 20828674 T PT20828674 T PT 20828674T PT 4069231 T PT4069231 T PT 4069231T
Authority
PT
Portugal
Prior art keywords
dementia
patients
methods
psychological symptoms
treating behavioral
Prior art date
Application number
PT208286740T
Other languages
English (en)
Original Assignee
Suven Life Sciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suven Life Sciences Ltd filed Critical Suven Life Sciences Ltd
Publication of PT4069231T publication Critical patent/PT4069231T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
PT208286740T 2019-12-02 2020-12-02 Combinações de masupirdina com donepezilo ou memantina para tratamento de sintomas comportamentais e psicológicos em pacientes com demência PT4069231T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN201941049515 2019-12-02
IN201941049513 2019-12-02

Publications (1)

Publication Number Publication Date
PT4069231T true PT4069231T (pt) 2025-08-01

Family

ID=73857227

Family Applications (1)

Application Number Title Priority Date Filing Date
PT208286740T PT4069231T (pt) 2019-12-02 2020-12-02 Combinações de masupirdina com donepezilo ou memantina para tratamento de sintomas comportamentais e psicológicos em pacientes com demência

Country Status (24)

Country Link
US (1) US20230000859A1 (pt)
EP (1) EP4069231B1 (pt)
JP (2) JP2023510082A (pt)
KR (1) KR20220110518A (pt)
CN (1) CN114761008B (pt)
AU (1) AU2020396396A1 (pt)
BR (1) BR112022010540A2 (pt)
DK (1) DK4069231T3 (pt)
ES (1) ES3036880T3 (pt)
FI (1) FI4069231T3 (pt)
HR (1) HRP20250882T1 (pt)
HU (1) HUE073179T2 (pt)
IL (1) IL293373A (pt)
LT (1) LT4069231T (pt)
MA (1) MA57828B1 (pt)
MD (1) MD4069231T2 (pt)
MX (1) MX2022006537A (pt)
PL (1) PL4069231T3 (pt)
PT (1) PT4069231T (pt)
RS (1) RS67022B1 (pt)
SI (1) SI4069231T1 (pt)
SM (1) SMT202500286T1 (pt)
WO (1) WO2021111320A1 (pt)
ZA (1) ZA202205914B (pt)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4559230B2 (ja) 2002-11-28 2010-10-06 スベン ライフ サイエンシズ リミティド セロトニン受容体に対する親和性を有する新規n−アリールスルホニル−3−置換されたインドール、その調製方法、それを含有する医薬組成物
EP1902733A1 (en) * 2006-09-19 2008-03-26 Laboratorios Del Dr. Esteve, S.A. Combination of a NMDA-receptor ligand and a compound with 5-HT6 receptor affinity
KR20140041670A (ko) * 2011-06-03 2014-04-04 엘란 파마슈티컬스, 엘엘씨 행동 장애 및 정신 장애의 치료를 위한 실로―이노시톨
HUE036008T2 (hu) 2013-12-02 2018-06-28 Suven Life Sciences Ltd Eljárás 1-[(2-brómfenil)szulfonil]-5-metoxi-3-[(4-metil-1-piperazinil)metil]-1H-indol-dimezilát-monohidrát nagyüzemi léptékben történõ elõállítására
US10864191B2 (en) 2016-05-11 2020-12-15 H. Lundbeck A/S 5-HT6 receptor antagonists for use in the treatment of Alzheimer's disease with apathy as comorbidity
EP3458040B1 (en) * 2016-05-18 2021-01-27 Suven Life Sciences Limited Combination of pure 5-ht6 receptor antagonists with nmda receptor antagonist
DK3458039T3 (da) * 2016-05-18 2020-09-14 Suven Life Sciences Ltd Tripelkombination af rene 5-ht6-receptorantagonister, acetylcholinesterasehæmmere og nmda-receptorantagonist
EA036347B1 (ru) 2016-05-18 2020-10-29 Сувен Лайф Сайенсиз Лимитед Комбинация чистых антагонистов 5-ht6 рецепторов с ингибиторами ацетилхолинэстеразы
CN110799189A (zh) 2017-07-03 2020-02-14 苏文生命科学有限公司 纯5-ht6受体拮抗剂的新用途

Also Published As

Publication number Publication date
BR112022010540A2 (pt) 2022-08-16
US20230000859A1 (en) 2023-01-05
NZ788970A (en) 2025-05-02
CN114761008B (zh) 2024-07-19
AU2020396396A1 (en) 2022-06-16
KR20220110518A (ko) 2022-08-08
WO2021111320A1 (en) 2021-06-10
PL4069231T3 (pl) 2025-09-08
LT4069231T (lt) 2025-09-10
DK4069231T3 (da) 2025-08-18
ES3036880T3 (en) 2025-09-25
EP4069231B1 (en) 2025-07-09
EP4069231A1 (en) 2022-10-12
RS67022B1 (sr) 2025-08-29
HUE073179T2 (hu) 2026-01-28
JP2023510082A (ja) 2023-03-13
MA57828B1 (fr) 2025-09-30
MX2022006537A (es) 2022-12-13
CA3162938A1 (en) 2021-06-10
SI4069231T1 (sl) 2025-10-30
IL293373A (en) 2022-07-01
HRP20250882T1 (hr) 2025-09-26
ZA202205914B (en) 2024-10-30
MD4069231T2 (ro) 2025-10-31
JP2024156953A (ja) 2024-11-06
FI4069231T3 (fi) 2025-08-15
SMT202500286T1 (it) 2025-09-12
CN114761008A (zh) 2022-07-15

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PT4069232T (pt) Masupirdina para tratar sintomas comportamentais e psicológicos na demência
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