PT65389B - Process for preparing an ophthalmic agent - Google Patents

Process for preparing an ophthalmic agent

Info

Publication number
PT65389B
PT65389B PT65389A PT6538976A PT65389B PT 65389 B PT65389 B PT 65389B PT 65389 A PT65389 A PT 65389A PT 6538976 A PT6538976 A PT 6538976A PT 65389 B PT65389 B PT 65389B
Authority
PT
Portugal
Prior art keywords
preparing
ophthalmic agent
ophthalmic
agent
Prior art date
Application number
PT65389A
Other languages
English (en)
Other versions
PT65389A (en
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of PT65389A publication Critical patent/PT65389A/pt
Publication of PT65389B publication Critical patent/PT65389B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A61K31/79—Polymers of vinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts or implants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT65389A 1975-07-29 1976-07-20 Process for preparing an ophthalmic agent PT65389B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60016875A 1975-07-29 1975-07-29

Publications (2)

Publication Number Publication Date
PT65389A PT65389A (en) 1976-08-01
PT65389B true PT65389B (en) 1978-06-09

Family

ID=24402570

Family Applications (1)

Application Number Title Priority Date Filing Date
PT65389A PT65389B (en) 1975-07-29 1976-07-20 Process for preparing an ophthalmic agent

Country Status (16)

Country Link
US (1) US4343787A (pt)
JP (1) JPS5215811A (pt)
AU (1) AU509140B2 (pt)
BE (1) BE844544A (pt)
BR (1) BR7604876A (pt)
CH (1) CH631891A5 (pt)
CY (1) CY1137A (pt)
DE (1) DE2633988C2 (pt)
ES (3) ES450002A1 (pt)
FR (1) FR2319375A1 (pt)
GB (1) GB1543189A (pt)
HK (1) HK282A (pt)
IT (1) IT1062653B (pt)
NL (1) NL188266C (pt)
PT (1) PT65389B (pt)
SE (1) SE431508B (pt)

Families Citing this family (98)

* Cited by examiner, † Cited by third party
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US4436730A (en) 1979-06-25 1984-03-13 Polymer Technology Corporation Ionic opthalmic cellulose polymer solutions
US4730013A (en) * 1981-10-08 1988-03-08 Merck & Co., Inc. Biosoluble ocular insert
FI831399A7 (fi) * 1982-04-29 1983-10-30 Agripat Sa Karkaistua polyvinyylialkoholia oleva piilolinssi
EP0108661A1 (en) * 1982-10-04 1984-05-16 Merck & Co. Inc. Stabilized hydroxypropyl cellulose ophthalmic inserts and process to sterilize the same
US4565198A (en) * 1983-12-27 1986-01-21 Barnes-Hind, Inc. Method for altering the curvature of the cornea
US4660546A (en) * 1984-11-07 1987-04-28 Robert S. Herrick Method for treating for deficiency of tears
US5209927A (en) * 1985-01-23 1993-05-11 Alcon Laboratories, Inc. Ophthalmic solution
US4826871A (en) * 1985-03-13 1989-05-02 Gressel Philip D Topical ophthalmic compositions containing one or more retinoids
FR2588189B1 (fr) * 1985-10-03 1988-12-02 Merck Sharp & Dohme Composition pharmaceutique de type a transition de phase liquide-gel
US4744980A (en) * 1986-04-28 1988-05-17 Holly Frank J Ophthalmic solution for treatment of dry eye syndrome
US4883658A (en) * 1986-04-28 1989-11-28 Holly Frank J Ophthalmic solution for treatment of dry-eye syndrome
US5229128A (en) * 1986-06-11 1993-07-20 Haddad Heskel M Drug delivery ophthalmic insert and method of preparing same
GB8623661D0 (en) * 1986-10-02 1986-11-05 Darougar S Ocular insert
US5322691A (en) * 1986-10-02 1994-06-21 Sohrab Darougar Ocular insert with anchoring protrusions
US5989579A (en) * 1986-10-02 1999-11-23 Escalon Medical Corp. Ocular insert with anchoring protrusions
US4966773A (en) * 1986-11-25 1990-10-30 Alcon Laboratories, Inc. Topical ophthalmic compositions containing microfine retinoid particles
CA1317226C (en) * 1987-05-04 1993-05-04 Phillip E. Pennell Viscoelastic fluid for ophthalmic surgery and method of using same
US5075104A (en) * 1989-03-31 1991-12-24 Alcon Laboratories, Inc. Ophthalmic carboxy vinyl polymer gel for dry eye syndrome
GB8917216D0 (en) * 1989-07-27 1989-09-13 Smith & Nephew Ophthalmic composition
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US5631004A (en) * 1993-09-30 1997-05-20 Alcon Laboratories, Inc. Use of sustained release antibiotic compositions in ophthalmic surgical procedures
TW274516B (pt) * 1993-11-12 1996-04-21 Ciba Geigy Ag
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US5518732A (en) * 1995-02-14 1996-05-21 Chiron Vision, Inc. Bio-erodible ophthalmic shield
DE19549506C2 (de) * 1995-03-07 1998-07-30 Richard Prof Dr Sueverkruep Darreichungsform zur äußerlichen Applikation und Verfahren zur Herstellung derselben
US6299895B1 (en) 1997-03-24 2001-10-09 Neurotech S.A. Device and method for treating ophthalmic diseases
US5888493A (en) * 1996-12-05 1999-03-30 Sawaya; Assad S. Ophthalmic aqueous gel formulation and related methods
US6193991B1 (en) * 1997-10-29 2001-02-27 Atul J. Shukla Biodegradable delivery systems of biologically active substances
JP2002538124A (ja) 1999-03-01 2002-11-12 ヴィスタ サイエンティフィック エルエルシー ムチンを含む眼科用調合物
US6264971B1 (en) 1999-11-04 2001-07-24 Btg International Limited Ocular insert
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JP2004511431A (ja) * 2000-06-28 2004-04-15 アトゥル・ジェイ・シュクラ 生物活性物質を含む生分解性ビヒクルおよび送達システム
US7404825B2 (en) * 2001-06-11 2008-07-29 Herrick Ii Robert S Implant capable of forming a differential image in an eye
EP2316394B1 (en) 2001-06-12 2016-11-23 The Johns Hopkins University Reservoir device for intraocular drug delivery
FR2833493B1 (fr) 2001-12-18 2005-09-23 Ioltechnologie Production Forme galenique solide et soluble pour l'administration occulaire de principes actifs et procede de fabrication d'un insert ophtalmique solide et soluble
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US7795203B2 (en) * 2002-09-30 2010-09-14 Babizhayev Mark A Method for topical treatment of eye disease and composition and device for said treatment
DE10246900A1 (de) 2002-10-08 2004-04-22 Horstmann, Michael, Dr. Am Auge applizierbare Vorrichtung zur sicheren Dosierung systemischer und tropischer Medikation
US7825134B2 (en) * 2003-05-19 2010-11-02 Othera Holding, Inc. Amelioration of cataracts, macular degeneration and other ophthalmic diseases
TWI336257B (en) * 2003-06-13 2011-01-21 Alcon Inc Ophthalmic compositions containing a synergistic combination of three polymers
CA2839849C (en) * 2003-06-13 2017-03-07 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of two polymers
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US7117870B2 (en) * 2004-07-26 2006-10-10 Clarity Corporation Lacrimal insert having reservoir with controlled release of medication and method of manufacturing the same
US20060068012A1 (en) * 2004-09-29 2006-03-30 Bausch & Lomb Incorporated Process for preparing poly (vinyl alcohol) drug delivery devices with humidity control
US20060067978A1 (en) * 2004-09-29 2006-03-30 Bausch & Lomb Incorporated Process for preparing poly(vinyl alcohol) drug delivery devices
CA2617040A1 (en) * 2005-07-29 2007-02-01 Santen Pharmaceutical Co., Ltd. Non-invasive drug delivery system targeting posterior eye tissue using solid composition
US20070264339A1 (en) * 2006-05-12 2007-11-15 Ap Pharma, Inc. Base-stabilized polyorthoester formulations
US20070265329A1 (en) * 2006-05-12 2007-11-15 Devang Shah T Methods for the prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV)
US20070264338A1 (en) * 2006-05-12 2007-11-15 Shah Devang T Base-stabilized polyorthoester formulations
KR101555291B1 (ko) * 2007-02-09 2015-09-30 알콘, 인코퍼레이티드 세가지 폴리머의 상승성 배합물을 함유하는 안과 조성물
CN103497148B (zh) 2007-02-22 2016-06-01 科尔比制药公司 羟胺化合物及其用法
JP2012512163A (ja) * 2008-12-11 2012-05-31 エーピー ファーマ， インコーポレイテッド ポリオルトエステルおよびそれらの製剤の安定性を高めるための方法
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US10166142B2 (en) 2010-01-29 2019-01-01 Forsight Vision4, Inc. Small molecule delivery with implantable therapeutic device
US8993626B2 (en) 2010-06-25 2015-03-31 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods of treatment using sterculic acid
HRP20230776T1 (hr) 2010-07-29 2023-10-27 Buzzard Pharmaceuticals AB Himerni antagonisti receptora il-1 tipa i
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US11617680B2 (en) 2016-04-05 2023-04-04 Forsight Vision4, Inc. Implantable ocular drug delivery devices
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CA3149866A1 (en) 2019-10-24 2021-04-29 Denis E. Labombard Ocular device and drug delivery system, with case
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USD1033637S1 (en) 2022-01-24 2024-07-02 Forsight Vision4, Inc. Fluid exchange device
WO2023214027A1 (en) 2022-05-06 2023-11-09 Eyed Pharma Insert for the treatment of dry eyes
BE1030503B1 (fr) 2022-05-06 2023-12-04 Eyed Pharma Insert pour le traitement de la sécheresse oculaire
BE1030504B1 (fr) 2022-05-06 2023-12-04 Eyed Pharma Insert composite pour le traitement de la sécheresse oculaire
WO2026087362A1 (en) * 2024-10-21 2026-04-30 Consejo Superior De Investigaciones Científicas (Csic) Ocular insert for use in the treatment of dry eye

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US3856919A (en) * 1970-06-08 1974-12-24 Burton Parsons Chemicals Inc Ophthalmic solution
US3767788A (en) * 1970-06-08 1973-10-23 Burton Parsons Chemicals Inc Ophthalmic solution
SE352811B (pt) * 1971-06-04 1973-01-15 Pharmacia Ab
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SE375007B (pt) * 1972-11-30 1975-04-07 Pharmacia Ab
US3875300A (en) * 1972-12-18 1975-04-01 Ortho Pharma Corp Composition for sustained release of a medicament and method of using same
US3911098A (en) * 1974-02-11 1975-10-07 American Cyanamid Co Medicament carrier

Also Published As

Publication number Publication date
NL188266B (nl) 1991-12-16
PT65389A (en) 1976-08-01
FR2319375A1 (fr) 1977-02-25
IT1062653B (it) 1984-10-20
CY1137A (en) 1982-05-07
AU509140B2 (en) 1980-04-24
JPS5215811A (en) 1977-02-05
CH631891A5 (en) 1982-09-15
ES450002A1 (es) 1977-11-16
FR2319375B1 (pt) 1982-07-23
HK282A (en) 1982-01-15
JPS6122975B2 (pt) 1986-06-03
DE2633988C2 (de) 1986-09-11
NL188266C (nl) 1992-05-18
AU1607776A (en) 1978-01-26
US4343787A (en) 1982-08-10
SE431508B (sv) 1984-02-13
BE844544A (fr) 1977-01-27
ES461216A1 (es) 1978-05-01
NL7607704A (nl) 1977-02-01
DE2633988A1 (de) 1977-02-10
GB1543189A (en) 1979-03-28
SE7608036L (sv) 1977-01-30
ES461217A1 (es) 1978-05-01
BR7604876A (pt) 1977-08-09

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