ES461216A1 - Un procedimiento para la preparacion de una insercion oftal-mica. - Google Patents

Un procedimiento para la preparacion de una insercion oftal-mica.

Info

Publication number
ES461216A1
ES461216A1 ES461216A ES461216A ES461216A1 ES 461216 A1 ES461216 A1 ES 461216A1 ES 461216 A ES461216 A ES 461216A ES 461216 A ES461216 A ES 461216A ES 461216 A1 ES461216 A1 ES 461216A1
Authority
ES
Spain
Prior art keywords
ophthal
mica
procedure
preparation
water soluble
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES461216A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES461216A1 publication Critical patent/ES461216A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A61K31/79—Polymers of vinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts or implants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Un procedimiento para la preparación de una inserción oftálmica mediante un procedimiento de moldeo por i nyección, que comprende las etapas de: a) calentar, en un recipiente equipado con un pistón móvil y en un extremo una abertura y un estator y un rotor, se calienta un polímero en polvo soluble en agua por encina de su temperatura de fusión hasta que todo el polvo de polímero se haya fundido y comience a fluir; b) hacer que la masa fundida de polímero se introduzca en un molde bajo la acción de presión creada por el movimiento de dicho pistón y el efecto de extrusión de fusión elástico provocado por el movimiento de dicho rotor; y c) separar la forma moldeada y cortada en inserción oftálmicas que tiene un área de superficie de alrededor de 5 a 800 mm2 una longitud de alrededor de 1 a 30 mm, y un ancho y altura de alrededor de 0,2 mm a 30 mm.
ES461216A 1975-07-29 1977-07-30 Un procedimiento para la preparacion de una insercion oftal-mica. Expired ES461216A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60016875A 1975-07-29 1975-07-29

Publications (1)

Publication Number Publication Date
ES461216A1 true ES461216A1 (es) 1978-05-01

Family

ID=24402570

Family Applications (3)

Application Number Title Priority Date Filing Date
ES450002A Expired ES450002A1 (es) 1975-07-29 1976-07-21 Un procedimiento para la preparacion de una insercion oftal-mica.
ES461216A Expired ES461216A1 (es) 1975-07-29 1977-07-30 Un procedimiento para la preparacion de una insercion oftal-mica.
ES461217A Expired ES461217A1 (es) 1975-07-29 1977-07-30 Un procedimiento para la preparacion de una insercion oftal-mica.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES450002A Expired ES450002A1 (es) 1975-07-29 1976-07-21 Un procedimiento para la preparacion de una insercion oftal-mica.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES461217A Expired ES461217A1 (es) 1975-07-29 1977-07-30 Un procedimiento para la preparacion de una insercion oftal-mica.

Country Status (16)

Country Link
US (1) US4343787A (es)
JP (1) JPS5215811A (es)
AU (1) AU509140B2 (es)
BE (1) BE844544A (es)
BR (1) BR7604876A (es)
CH (1) CH631891A5 (es)
CY (1) CY1137A (es)
DE (1) DE2633988C2 (es)
ES (3) ES450002A1 (es)
FR (1) FR2319375A1 (es)
GB (1) GB1543189A (es)
HK (1) HK282A (es)
IT (1) IT1062653B (es)
NL (1) NL188266C (es)
PT (1) PT65389B (es)
SE (1) SE431508B (es)

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Also Published As

Publication number Publication date
FR2319375A1 (fr) 1977-02-25
IT1062653B (it) 1984-10-20
GB1543189A (en) 1979-03-28
NL7607704A (nl) 1977-02-01
HK282A (en) 1982-01-15
FR2319375B1 (es) 1982-07-23
US4343787A (en) 1982-08-10
DE2633988A1 (de) 1977-02-10
NL188266C (nl) 1992-05-18
BR7604876A (pt) 1977-08-09
PT65389A (en) 1976-08-01
NL188266B (nl) 1991-12-16
AU1607776A (en) 1978-01-26
SE431508B (sv) 1984-02-13
ES450002A1 (es) 1977-11-16
CH631891A5 (en) 1982-09-15
ES461217A1 (es) 1978-05-01
SE7608036L (sv) 1977-01-30
DE2633988C2 (de) 1986-09-11
BE844544A (fr) 1977-01-27
CY1137A (en) 1982-05-07
PT65389B (en) 1978-06-09
JPS5215811A (en) 1977-02-05
JPS6122975B2 (es) 1986-06-03
AU509140B2 (en) 1980-04-24

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