PT733104E - Purificacao de proteinas dependentes de vitamina k por cromatografia de membrana - Google Patents

Purificacao de proteinas dependentes de vitamina k por cromatografia de membrana

Info

Publication number
PT733104E
PT733104E PT95903324T PT95903324T PT733104E PT 733104 E PT733104 E PT 733104E PT 95903324 T PT95903324 T PT 95903324T PT 95903324 T PT95903324 T PT 95903324T PT 733104 E PT733104 E PT 733104E
Authority
PT
Portugal
Prior art keywords
vitamin
purification
dependent proteins
membrane chromatography
protein
Prior art date
Application number
PT95903324T
Other languages
English (en)
Inventor
Djuro Josic
Ales Strancar
Original Assignee
Octapharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Octapharma Ag filed Critical Octapharma Ag
Publication of PT733104E publication Critical patent/PT733104E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/647—Blood coagulation factors not provided for in a preceding group or according to more than one of the proceeding groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Peptides Or Proteins (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT95903324T 1993-12-10 1994-12-07 Purificacao de proteinas dependentes de vitamina k por cromatografia de membrana PT733104E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4342132A DE4342132C1 (de) 1993-12-10 1993-12-10 Verfahren zur Herstellung virusinaktivierte Vitamin K abhängige Plasmakomponenten sowie Protein C und Protein S enthaltender Mittel durch Membran-Chromatographie

Publications (1)

Publication Number Publication Date
PT733104E true PT733104E (pt) 2004-12-31

Family

ID=6504650

Family Applications (1)

Application Number Title Priority Date Filing Date
PT95903324T PT733104E (pt) 1993-12-10 1994-12-07 Purificacao de proteinas dependentes de vitamina k por cromatografia de membrana

Country Status (19)

Country Link
US (2) US20020045240A1 (pt)
EP (1) EP0733104B1 (pt)
JP (1) JPH09506256A (pt)
KR (1) KR100320394B1 (pt)
CN (1) CN1175105C (pt)
AT (1) ATE276357T1 (pt)
AU (1) AU682560B2 (pt)
CA (1) CA2178208C (pt)
CZ (1) CZ291708B6 (pt)
DE (2) DE4342132C1 (pt)
DK (1) DK0733104T3 (pt)
ES (1) ES2224119T3 (pt)
HU (1) HU222084B1 (pt)
IL (1) IL111925A (pt)
PL (1) PL180179B1 (pt)
PT (1) PT733104E (pt)
UA (1) UA44261C2 (pt)
WO (1) WO1995016030A1 (pt)
ZA (1) ZA949820B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT409334B (de) * 1997-09-19 2002-07-25 Immuno Ag Pharmazeutisches präparat enthaltend vitamin k-abhängige einzelfaktoren
EP3087991A1 (en) 2003-11-08 2016-11-02 Prothera Biologics Composition of inter-alpha inhibitor proteins from human plasma for therapeutic use
JP2005315666A (ja) * 2004-04-28 2005-11-10 Toshihiko Hanai 糖結合充填剤およびその製造方法
JP2008525381A (ja) * 2004-12-23 2008-07-17 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト 関心のあるビタミンｋ依存性タンパク質を含んでなる組成物中におけるタンパク質混入物の量の減少
KR100667860B1 (ko) 2005-10-18 2007-01-11 주식회사 녹십자 고순도 사람 혈액응고 제9인자의 정제 방법
JP5883849B2 (ja) * 2010-04-29 2016-03-15 バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ 陰イオン交換樹脂を用いる二価カチオン結合タンパク質の精製方法
AU2011343813B2 (en) 2010-12-15 2015-05-21 Takeda Pharmaceutical Company Limited Eluate collection using conductivity gradient
CN103665098B (zh) * 2012-09-20 2015-08-05 中国科学院大连化学物理研究所 双相柱膜蛋白质微反应器及其应用
CN104447975A (zh) * 2014-11-18 2015-03-25 深圳市人口和计划生育科学研究所 一种提取人肿瘤细胞膜蛋白的方法
JP7432506B2 (ja) 2017-10-30 2024-02-16 武田薬品工業株式会社 脂質エンベロープウイルスを不活化するための環境適合性の界面活性剤
CN111378029B (zh) * 2018-12-29 2023-05-05 四川远大蜀阳药业有限责任公司 一种人凝血因子ix的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0050061B2 (en) * 1980-10-06 1990-06-20 New York Blood Center, Inc. Method of reducing undesirable activities of biological and pharmaceutical products
DE3045153A1 (de) * 1980-11-29 1982-07-08 Behringwerke Ag, 3550 Marburg Verfahren zur herstellung von blutgerinnungsfaktoren und danach hergestellte praeparation der faktoren ix und x
US4820805A (en) * 1983-07-14 1989-04-11 New York Blood Center, Inc. Undenatured virus-free trialkyl phosphate treated biologically active protein derivatives
US4540573A (en) * 1983-07-14 1985-09-10 New York Blood Center, Inc. Undenatured virus-free biologically active protein derivatives
ATE130620T1 (de) * 1986-01-06 1995-12-15 Blood Systems Inc Therapeutisches blutprodukt, mittel und verfahren zu dessen erzeugung.
EP0317376B2 (fr) * 1987-10-23 1996-04-03 Centre Regional De Transfusion Sanguine De Lille Préparation de concentré de facteur IX humain de haute pureté et d'autres protéines plasmatiques
CA2001720C (en) * 1988-10-31 2001-10-02 Randal A. Goffe Membrane affinity apparatus and purification methods related thereto
DE3914869C1 (pt) * 1989-05-05 1990-08-09 Biotest Pharma Gmbh, 6072 Dreieich, De
EP0513332A4 (en) * 1990-11-14 1993-03-17 Cargill, Incorporated Conjugates of poly(vinylsaccharide) with proteins for the stabilization of proteins
AT402261B (de) * 1991-01-25 1997-03-25 Immuno Ag Komplex enthaltend den gerinnungsfaktor ix
AT402891B (de) * 1991-06-20 1997-09-25 Immuno Ag Verfahren zur herstellung eines inaktivierten blutproduktes
DE4204694C3 (de) * 1992-02-01 1995-10-12 Octapharma Ag Verfahren zur Gewinnung von hochreinem, virusinaktiviertem Faktor VIII mittels Anionenaustauscher-Chromatographie

Also Published As

Publication number Publication date
CA2178208C (en) 2009-06-02
US6893856B2 (en) 2005-05-17
CN1137292A (zh) 1996-12-04
EP0733104A1 (en) 1996-09-25
WO1995016030A1 (en) 1995-06-15
DE4342132C1 (de) 1994-11-03
CZ167096A3 (en) 1996-09-11
IL111925A (en) 2000-06-01
CZ291708B6 (cs) 2003-05-14
US20020045240A1 (en) 2002-04-18
ES2224119T3 (es) 2005-03-01
EP0733104B1 (en) 2004-09-15
CA2178208A1 (en) 1995-06-15
UA44261C2 (uk) 2002-02-15
DE69434001D1 (de) 2004-10-21
HUT76881A (en) 1997-12-29
IL111925A0 (en) 1995-03-15
DK0733104T3 (da) 2005-01-17
ATE276357T1 (de) 2004-10-15
KR100320394B1 (ko) 2002-07-31
HU222084B1 (hu) 2003-04-28
CN1175105C (zh) 2004-11-10
AU682560B2 (en) 1997-10-09
JPH09506256A (ja) 1997-06-24
PL314801A1 (en) 1996-09-30
ZA949820B (en) 1995-08-16
DE69434001T2 (de) 2005-09-22
HU9601594D0 (en) 1996-07-29
PL180179B1 (pl) 2000-12-29
US20020182582A1 (en) 2002-12-05
AU1242595A (en) 1995-06-27

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