PT84404B - Processo para a preparacao de 2-alcoxi-n-(1-azabiciclo {2.2.2} octil-3)-benzamidas e tiobenzamidas apropriadas para aliviar a emese provocada por drogas anti-cancro sem platina - Google Patents

Processo para a preparacao de 2-alcoxi-n-(1-azabiciclo {2.2.2} octil-3)-benzamidas e tiobenzamidas apropriadas para aliviar a emese provocada por drogas anti-cancro sem platina

Info

Publication number
PT84404B
PT84404B PT84404A PT8440487A PT84404B PT 84404 B PT84404 B PT 84404B PT 84404 A PT84404 A PT 84404A PT 8440487 A PT8440487 A PT 8440487A PT 84404 B PT84404 B PT 84404B
Authority
PT
Portugal
Prior art keywords
tiobenzamids
emase
ocyl
alcoxy
benzamides
Prior art date
Application number
PT84404A
Other languages
English (en)
Other versions
PT84404A (en
Inventor
William Levi Smith
Reevis Stancil Alphin
Harry Randall Munson Jr
Robert Frederick Boswell
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of PT84404A publication Critical patent/PT84404A/pt
Publication of PT84404B publication Critical patent/PT84404B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT84404A 1986-03-05 1987-03-04 Processo para a preparacao de 2-alcoxi-n-(1-azabiciclo {2.2.2} octil-3)-benzamidas e tiobenzamidas apropriadas para aliviar a emese provocada por drogas anti-cancro sem platina PT84404B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/836,518 US4717563A (en) 1986-03-05 1986-03-05 2-alkoxy-N-(1-azabicyclo(2.2.2)oct-3-yl) benzamides and thiobenzamides in a method for alleviating emesis caused by non-platinum anticancer drugs

Publications (2)

Publication Number Publication Date
PT84404A PT84404A (en) 1987-04-01
PT84404B true PT84404B (pt) 1989-10-04

Family

ID=25272132

Family Applications (1)

Application Number Title Priority Date Filing Date
PT84404A PT84404B (pt) 1986-03-05 1987-03-04 Processo para a preparacao de 2-alcoxi-n-(1-azabiciclo {2.2.2} octil-3)-benzamidas e tiobenzamidas apropriadas para aliviar a emese provocada por drogas anti-cancro sem platina

Country Status (11)

Country Link
US (1) US4717563A (pt)
EP (1) EP0240180A1 (pt)
JP (1) JPH0681723B2 (pt)
KR (1) KR870008886A (pt)
AU (1) AU592623B2 (pt)
CA (1) CA1284953C (pt)
DK (1) DK112287A (pt)
HU (1) HU197842B (pt)
PH (1) PH22678A (pt)
PT (1) PT84404B (pt)
ZA (1) ZA871304B (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4888353A (en) * 1986-02-28 1989-12-19 Erbamont, Inc. Carboxamides useful as antiemetic or antipsychotic agents
US4820715A (en) * 1984-06-28 1989-04-11 Bristol-Myers Company Anti-emetic quinuclidinyl benzamides
US4772459A (en) * 1986-09-09 1988-09-20 Erbamont, Inc. Method for controlling emesis caused by chemotherapeutic agents and antiemetic agents useful therein
US5246941A (en) * 1986-12-17 1993-09-21 Glaxo Group Limited Method for the treatment of depression
GB8718345D0 (en) * 1987-08-03 1987-09-09 Fordonal Sa N-substituted benzamides
US5206246A (en) * 1987-10-16 1993-04-27 A. H. Robins Company, Incorporated Anxiolytic-R-n(1-azabicyclo[2.2.2]oct-3-yl) benzamides and thiobenzamides
CA1304082C (en) * 1987-10-22 1992-06-23 Tetsuya Tahara Benzoxazine compounds and pharmaceutical use thereof
US4863919A (en) * 1988-02-01 1989-09-05 A. H. Robins Company, Incorporated Method of enhancing memory or correcting memory deficiency with arylamido(and arylthiomido)-azabicycloalkanes
US5039528A (en) * 1989-12-11 1991-08-13 Olney John W EAA antagonists as anti-emetic drugs
US5723103A (en) * 1994-12-09 1998-03-03 Vanderbilt University Substituted benzamides and radioligand analogs and methods of use
US6479510B2 (en) 2000-08-18 2002-11-12 Pharmacia & Upjohn Company Quinuclidine-substituted aryl compounds for treatment of disease
WO2002016357A2 (en) 2000-08-18 2002-02-28 Pharmacia & Upjohn Company Quinuclidine-substituted aryl moieties for treatment of disease (nicotinic acetylcholine receptor ligands)
PE20021019A1 (es) 2001-04-19 2002-11-13 Upjohn Co Grupos azabiciclicos sustituidos
JP2005504059A (ja) * 2001-08-24 2005-02-10 ファルマシア アンド アップジョン カンパニー リミティド ライアビリティー カンパニー 疾患を処置するための置換アリール７−アザ［２．２．１］ビシクロヘプタン
EP1480977A2 (en) 2002-02-15 2004-12-01 PHARMACIA & UPJOHN COMPANY Substituted aryl compounds for treatment of disease
WO2003072578A1 (en) * 2002-02-20 2003-09-04 Pharmacia & Upjohn Company Azabicyclic compounds with alfa7 nicotinic acetylcholine receptor activity
EP2344636B1 (en) 2008-10-09 2017-12-06 Howard Hughes Medical Institute Novel chimeric ligand-gated ion channels and methods of use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2548968A1 (de) * 1975-11-03 1977-05-12 Thomae Gmbh Dr K Neue amino-benzoesaeureamide
US4536386B1 (en) * 1981-01-26 1995-03-07 Robins Co Inc A H Method of controlling emesis caused by cisplatin in cancer chemotherapy
FR2531083B1 (fr) * 1982-06-29 1986-11-28 Sandoz Sa Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments
FR2529548A1 (fr) * 1982-07-02 1984-01-06 Delalande Sa Nouveaux derives de l'amino-3 quinuclidine, leur procede et leur application en therapeutique
WO1985001048A1 (en) * 1983-08-26 1985-03-14 Sandoz Ag Aromatic esters or amides of carboxylic acid and sulfonic acid
US4593034A (en) * 1984-04-06 1986-06-03 A. H. Robins Company, Inc. 2-alkoxy-N-(1-azabicyclo[2.2.2]oct-3-yl)benzamides and thiobenzamides

Also Published As

Publication number Publication date
CA1284953C (en) 1991-06-18
ZA871304B (en) 1987-11-25
DK112287D0 (da) 1987-03-04
PT84404A (en) 1987-04-01
KR870008886A (ko) 1987-10-21
AU592623B2 (en) 1990-01-18
DK112287A (da) 1987-09-06
HU197842B (en) 1989-06-28
AU6904687A (en) 1987-09-10
EP0240180A1 (en) 1987-10-07
US4717563A (en) 1988-01-05
JPH0681723B2 (ja) 1994-10-19
PH22678A (en) 1988-11-14
HUT43955A (en) 1988-01-28
JPS62228016A (ja) 1987-10-06

Similar Documents

Publication Publication Date Title
BR8805440A (pt) Processo para a fabricacao de 1,1,1-trifluorodicloroetano e/ou 1,1,1,2-tetrafluorocloroetano por fluoracao de um tetrahaloetileno
PT84404B (pt) Processo para a preparacao de 2-alcoxi-n-(1-azabiciclo {2.2.2} octil-3)-benzamidas e tiobenzamidas apropriadas para aliviar a emese provocada por drogas anti-cancro sem platina
PT84316B (pt) Processo para a preparacao de cicloalcano {1,2 -b} indole-sulfamidas
BR8703376A (pt) Processo para a preparacao de alfa-aril-alfa-feniletil-1h-1,2,4-triazol-1-propanonitrilas e composicoes fungicidas com base nas mesmas
FI872379A7 (fi) Menetelmä farmakologisesti vaikuttavien 1,5-diaryyli-3-(w-substituoitu-alempi-alkyyli)-pyratsolien valmistamiseksi
BR8803759A (pt) Processo para a preparacao de 2,2,6,6-tetrametil-4-piperidilaminas
PT89113A (pt) Dispositivo e processo para a administracao de farmacos
BR8704144A (pt) Ingrediente anti-espumante em particulas e processo para a preparacao de um ingrediente anti-espumante
BR8902297A (pt) Processo para a preparacao de 1,1,1,2-tetrafluoretano
BR9003345A (pt) Processo para a preparacao de 1,1,1,2-tetrafluoretano
BR8704955A (pt) Solido catalitico a base de tricloreto de titanio e processo para a preparacao de um solido catalitico
BR8605269A (pt) Processo para preparacao de(2,2)-paraciclofano
BR8802843A (pt) Processo para a preparacao de alcanotriois e alcanopoliois
ES2021411B3 (es) Proceso para la preparacion de (2,2) paraciclofano.
BR8803697A (pt) Processo para a preparacao de um polimero hidrogenado funcionalizado e copolimero funcionalizado
BR8907583A (pt) Processo para preparacao de 2',3'-dideoxinucleosideos
PT89204A (pt) Processo para a preparacao de um agente edulcorante
PT84459B (pt) Processo para a preparacao de derivados de ciclopropano 1,1-dissubstituidos
IT8620796A0 (it) Processo per la preparazione dell'n-dimetilchitosano e suoi impieghi farmacologici.
PT93736A (pt) Processo para a preparacao de n,n'-ditrimetoxi-benzoil-piperazinas 2- substituidas
PT90816A (pt) Processo para a preparacao de composicoes farmaceuticas contendo analogos de 2',5'-oligoadenilato
BR8704522A (pt) Processo para a preparacao de tetracloreto de titanio
BR9003346A (pt) Processo para a preparacao de 1,2-dicloro-1,1,2-trifluoretano
PT84405B (pt) Processo para a preparacao de composicoes farmaceuticas contendo 2-alcoxi-n-(1-azabiciclo {2.2.2} octil-3-benzamida-n-oxidos apropriadas para controlar a emese provocada por drogas anti-cancro
PT89262A (pt) Processo para a preparacao de peptideos ciclicos

Legal Events

Date Code Title Description
PC3A Transfer or assignment

Free format text: 921231 A.H. ROBINS COMPANY, INCORPORATED US

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19950930