PT84405B - Processo para a preparacao de composicoes farmaceuticas contendo 2-alcoxi-n-(1-azabiciclo {2.2.2} octil-3-benzamida-n-oxidos apropriadas para controlar a emese provocada por drogas anti-cancro - Google Patents

Processo para a preparacao de composicoes farmaceuticas contendo 2-alcoxi-n-(1-azabiciclo {2.2.2} octil-3-benzamida-n-oxidos apropriadas para controlar a emese provocada por drogas anti-cancro

Info

Publication number
PT84405B
PT84405B PT84405A PT8440587A PT84405B PT 84405 B PT84405 B PT 84405B PT 84405 A PT84405 A PT 84405A PT 8440587 A PT8440587 A PT 8440587A PT 84405 B PT84405 B PT 84405B
Authority
PT
Portugal
Prior art keywords
octil
alcoxy
azabicyclo
benzamide
preparation
Prior art date
Application number
PT84405A
Other languages
English (en)
Other versions
PT84405A (en
Inventor
William Levi Smith
Lina Chen Teng
Stephen Clyde Bearekman
Lennox Birckhead Turnbull
Reevis Stancil Alphin
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of PT84405A publication Critical patent/PT84405A/pt
Publication of PT84405B publication Critical patent/PT84405B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT84405A 1986-03-05 1987-03-04 Processo para a preparacao de composicoes farmaceuticas contendo 2-alcoxi-n-(1-azabiciclo {2.2.2} octil-3-benzamida-n-oxidos apropriadas para controlar a emese provocada por drogas anti-cancro PT84405B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/836,521 US4722834A (en) 1986-03-05 1986-03-05 Method of using 2-alkoxy-N-(1-azabicyclo[2.2.2]oct-3-yl)benzamide-N-oxides to control emesis caused by anticancer drugs

Publications (2)

Publication Number Publication Date
PT84405A PT84405A (en) 1987-04-01
PT84405B true PT84405B (pt) 1989-10-04

Family

ID=25272139

Family Applications (1)

Application Number Title Priority Date Filing Date
PT84405A PT84405B (pt) 1986-03-05 1987-03-04 Processo para a preparacao de composicoes farmaceuticas contendo 2-alcoxi-n-(1-azabiciclo {2.2.2} octil-3-benzamida-n-oxidos apropriadas para controlar a emese provocada por drogas anti-cancro

Country Status (11)

Country Link
US (1) US4722834A (pt)
EP (1) EP0237281A1 (pt)
JP (1) JPS62230724A (pt)
KR (1) KR870008885A (pt)
AU (1) AU597036B2 (pt)
CA (1) CA1277917C (pt)
HU (1) HU197843B (pt)
IL (1) IL81834A0 (pt)
PH (1) PH23752A (pt)
PT (1) PT84405B (pt)
ZA (1) ZA871110B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4888353A (en) * 1986-02-28 1989-12-19 Erbamont, Inc. Carboxamides useful as antiemetic or antipsychotic agents
US4772459A (en) * 1986-09-09 1988-09-20 Erbamont, Inc. Method for controlling emesis caused by chemotherapeutic agents and antiemetic agents useful therein
EP0311724A1 (en) * 1987-10-16 1989-04-19 Synthelabo Anxiolytic-R-N-(1-azabicyclo[2.2.2]oct-3-yl) benzamides and thiobenzamides
US5192770A (en) * 1990-12-07 1993-03-09 Syntex (U.S.A.) Inc. Serotonergic alpha-oxoacetamides
US5723103A (en) * 1994-12-09 1998-03-03 Vanderbilt University Substituted benzamides and radioligand analogs and methods of use
WO2010042799A2 (en) 2008-10-09 2010-04-15 Howard Hughes Medical Institute Novel chimeric ligand-gated ion channels and methods of use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2548968A1 (de) * 1975-11-03 1977-05-12 Thomae Gmbh Dr K Neue amino-benzoesaeureamide
US4536386B1 (en) * 1981-01-26 1995-03-07 Robins Co Inc A H Method of controlling emesis caused by cisplatin in cancer chemotherapy
AU1508183A (en) * 1982-06-04 1983-12-08 Beecham Group Plc Benzamide and anilide derivatives of 8-azabicyclo-(3.2.1)- -octane
FR2531083B1 (fr) * 1982-06-29 1986-11-28 Sandoz Sa Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments
FR2529548A1 (fr) * 1982-07-02 1984-01-06 Delalande Sa Nouveaux derives de l'amino-3 quinuclidine, leur procede et leur application en therapeutique
US4593034A (en) * 1984-04-06 1986-06-03 A. H. Robins Company, Inc. 2-alkoxy-N-(1-azabicyclo[2.2.2]oct-3-yl)benzamides and thiobenzamides

Also Published As

Publication number Publication date
PH23752A (en) 1989-11-03
PT84405A (en) 1987-04-01
AU6968987A (en) 1987-09-10
ZA871110B (en) 1987-11-25
JPS62230724A (ja) 1987-10-09
HUT43490A (en) 1987-11-30
CA1277917C (en) 1990-12-18
EP0237281A1 (en) 1987-09-16
IL81834A0 (en) 1987-10-20
KR870008885A (ko) 1987-10-21
HU197843B (en) 1989-06-28
AU597036B2 (en) 1990-05-24
US4722834A (en) 1988-02-02

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Legal Events

Date Code Title Description
PC3A Transfer or assignment

Free format text: 921231 A.H. ROBINS COMPANY, INCORPORATED US

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19940930