PT86851A - Procede de preparation des nouveaux derives de l:acide (dihydri-2,3,oxo-2 benzofurannyl-3)-2 acetique - Google Patents
Procede de preparation des nouveaux derives de l:acide (dihydri-2,3,oxo-2 benzofurannyl-3)-2 acetiqueInfo
- Publication number
- PT86851A PT86851A PT86851A PT8685188A PT86851A PT 86851 A PT86851 A PT 86851A PT 86851 A PT86851 A PT 86851A PT 8685188 A PT8685188 A PT 8685188A PT 86851 A PT86851 A PT 86851A
- Authority
- PT
- Portugal
- Prior art keywords
- radical
- carbon atoms
- denotes
- linear
- optionally substituted
- Prior art date
Links
- -1 alkyl radical Chemical class 0.000 abstract 18
- 125000004432 carbon atom Chemical group C* 0.000 abstract 13
- 150000003254 radicals Chemical class 0.000 abstract 5
- TUJKJAMUKRIRHC-UHFFFAOYSA-N hydroxyl Chemical compound [OH] TUJKJAMUKRIRHC-UHFFFAOYSA-N 0.000 abstract 3
- SLRMQYXOBQWXCR-UHFFFAOYSA-N 2154-56-5 Chemical group [CH2]C1=CC=CC=C1 SLRMQYXOBQWXCR-UHFFFAOYSA-N 0.000 abstract 2
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical group [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- KZKRRZFCAYOXQE-UHFFFAOYSA-N 1$l^{2}-azinane Chemical group C1CC[N]CC1 KZKRRZFCAYOXQE-UHFFFAOYSA-N 0.000 abstract 1
- PKMIRTMPTNEWOJ-UHFFFAOYSA-N 2-(2-oxo-3h-1-benzofuran-3-yl)acetic acid Chemical class C1=CC=C2C(CC(=O)O)C(=O)OC2=C1 PKMIRTMPTNEWOJ-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/83—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8702630A FR2611713B1 (fr) | 1987-02-27 | 1987-02-27 | Nouveaux derives de l'acide (dihydro-2,3 oxo-2 benzofurannyl-3)-2 acetique, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT86851A true PT86851A (pt) | 1988-03-01 |
| PT86851B PT86851B (pt) | 1992-05-29 |
Family
ID=9348401
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT86851A PT86851B (pt) | 1987-02-27 | 1988-02-26 | Processo para a preparacao de novos derivados do acido 2-(2,3-dihidro-2-oxo-3-benzofuranil)-acetico |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US4859700A (pt) |
| EP (1) | EP0282390B1 (pt) |
| JP (1) | JPS63227582A (pt) |
| AT (1) | ATE63309T1 (pt) |
| AU (1) | AU598345B2 (pt) |
| CA (1) | CA1313871C (pt) |
| DE (1) | DE3862660D1 (pt) |
| DK (1) | DK167063B1 (pt) |
| ES (1) | ES2009553A6 (pt) |
| FR (1) | FR2611713B1 (pt) |
| GR (1) | GR1000125B (pt) |
| IE (1) | IE60500B1 (pt) |
| NZ (1) | NZ223663A (pt) |
| OA (1) | OA08813A (pt) |
| PT (1) | PT86851B (pt) |
| ZA (1) | ZA881383B (pt) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2061953T3 (es) * | 1988-11-24 | 1994-12-16 | Akzo Nv | Un procedimiento para preparar una composicion farmaceutica. |
| GB9024960D0 (en) * | 1990-11-16 | 1991-01-02 | Ici Plc | Chemical process |
| GB9205049D0 (en) * | 1992-03-09 | 1992-04-22 | Ici Plc | Polycyclic dyes |
| US6207665B1 (en) * | 1997-06-12 | 2001-03-27 | Schering Aktiengesellschaft | Piperazine derivatives and their use as anti-inflammatory agents |
| CA2415815A1 (en) * | 2000-07-06 | 2002-01-17 | Nigel H. Greig | Tetrahydrobenzothiazole analogues as neuroprotective agents |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2513698A (en) * | 1945-03-09 | 1950-07-04 | Abbott Lab | 2 (3) benxofuranone derivatives and methods of making them |
| GB1173312A (en) * | 1966-03-17 | 1969-12-10 | Kefalas As | Heterocyclic Compounds |
| GB2044272B (en) * | 1979-02-05 | 1983-03-16 | Sandoz Ltd | Stabilising polymers |
| US4514415A (en) * | 1981-10-28 | 1985-04-30 | Ciba Geigy Corporation | Benzofuran-2(3H)-ones used as anti-inflammatory agents |
| US4663347A (en) * | 1983-10-31 | 1987-05-05 | Merck Frosst Canada, Inc. | Benzofuran 2-carboxylic acid esters useful as inhibitors of leukotriene biosynthesis |
| GB8426424D0 (en) * | 1984-10-19 | 1984-11-28 | Biorex Laboratories Ltd | Chalcone derivatives |
| FR2593504B1 (fr) * | 1986-01-30 | 1988-12-09 | Ile De France | Nouveaux derives de dihydrobenzofuranne - et de chromane - carboxamides, leurs procedes de preparation et leur utilisation comme neuroleptiques |
-
1987
- 1987-02-27 FR FR8702630A patent/FR2611713B1/fr not_active Expired - Lifetime
-
1988
- 1988-02-01 CA CA000557812A patent/CA1313871C/fr not_active Expired - Fee Related
- 1988-02-12 US US07/155,352 patent/US4859700A/en not_active Expired - Fee Related
- 1988-02-26 AU AU12344/88A patent/AU598345B2/en not_active Ceased
- 1988-02-26 OA OA59290A patent/OA08813A/xx unknown
- 1988-02-26 EP EP19880400441 patent/EP0282390B1/fr not_active Expired - Lifetime
- 1988-02-26 AT AT88400441T patent/ATE63309T1/de not_active IP Right Cessation
- 1988-02-26 DK DK104388A patent/DK167063B1/da not_active IP Right Cessation
- 1988-02-26 NZ NZ223663A patent/NZ223663A/en unknown
- 1988-02-26 IE IE52888A patent/IE60500B1/en not_active IP Right Cessation
- 1988-02-26 GR GR880100111A patent/GR1000125B/el unknown
- 1988-02-26 DE DE8888400441T patent/DE3862660D1/de not_active Expired - Lifetime
- 1988-02-26 ZA ZA881383A patent/ZA881383B/xx unknown
- 1988-02-26 PT PT86851A patent/PT86851B/pt not_active IP Right Cessation
- 1988-02-26 JP JP63044081A patent/JPS63227582A/ja active Granted
- 1988-02-27 ES ES8800577A patent/ES2009553A6/es not_active Expired
-
1989
- 1989-01-17 US US07/298,107 patent/US4885299A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ZA881383B (en) | 1988-12-28 |
| DK167063B1 (da) | 1993-08-23 |
| GR1000125B (el) | 1991-07-31 |
| EP0282390B1 (fr) | 1991-05-08 |
| JPH0558633B2 (pt) | 1993-08-27 |
| DK104388A (da) | 1988-08-28 |
| ES2009553A6 (es) | 1989-10-01 |
| AU1234488A (en) | 1988-09-01 |
| US4885299A (en) | 1989-12-05 |
| IE60500B1 (en) | 1994-07-27 |
| OA08813A (fr) | 1989-03-31 |
| PT86851B (pt) | 1992-05-29 |
| DE3862660D1 (de) | 1991-06-13 |
| JPS63227582A (ja) | 1988-09-21 |
| ATE63309T1 (de) | 1991-05-15 |
| NZ223663A (en) | 1990-01-29 |
| US4859700A (en) | 1989-08-22 |
| IE880528L (en) | 1988-08-27 |
| GR880100111A (en) | 1988-12-16 |
| EP0282390A1 (fr) | 1988-09-14 |
| AU598345B2 (en) | 1990-06-21 |
| FR2611713A1 (fr) | 1988-09-09 |
| CA1313871C (fr) | 1993-02-23 |
| DK104388D0 (da) | 1988-02-26 |
| FR2611713B1 (fr) | 1990-11-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Patent granted, date of granting |
Effective date: 19911115 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19970531 |