PT87197A - Processo para preparacao de agentes terapeuticos eritropoietina - Google Patents
Processo para preparacao de agentes terapeuticos eritropoietinaInfo
- Publication number
- PT87197A PT87197A PT87197A PT8719788A PT87197A PT 87197 A PT87197 A PT 87197A PT 87197 A PT87197 A PT 87197A PT 8719788 A PT8719788 A PT 8719788A PT 87197 A PT87197 A PT 87197A
- Authority
- PT
- Portugal
- Prior art keywords
- eritropoietin
- preparation
- therapeutic agents
- mammal
- epo
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title 1
- 229940124597 therapeutic agent Drugs 0.000 title 1
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract 4
- 102000003951 Erythropoietin Human genes 0.000 abstract 3
- 108090000394 Erythropoietin Proteins 0.000 abstract 3
- 241000124008 Mammalia Species 0.000 abstract 3
- 229940105423 erythropoietin Drugs 0.000 abstract 3
- OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical compound [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 abstract 3
- 238000005534 hematocrit Methods 0.000 abstract 2
- 229910052742 iron Inorganic materials 0.000 abstract 2
- 230000010437 erythropoiesis Effects 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Electrotherapy Devices (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3664687A | 1987-04-10 | 1987-04-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT87197A true PT87197A (pt) | 1988-05-01 |
| PT87197B PT87197B (pt) | 1992-07-31 |
Family
ID=21889805
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT87197A PT87197B (pt) | 1987-04-10 | 1988-04-08 | Processo para a preparacao de agentes terapeuticos contendo eritropoietina |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5541158A (pt) |
| EP (1) | EP0286439B1 (pt) |
| JP (1) | JP2858752B2 (pt) |
| KR (1) | KR880012235A (pt) |
| AT (1) | ATE70978T1 (pt) |
| AU (1) | AU613905B2 (pt) |
| DE (1) | DE3867285D1 (pt) |
| DK (1) | DK167903B1 (pt) |
| ES (1) | ES2035279T3 (pt) |
| GR (1) | GR3004071T3 (pt) |
| IE (1) | IE61008B1 (pt) |
| NO (1) | NO881507D0 (pt) |
| PT (1) | PT87197B (pt) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2686899B1 (fr) | 1992-01-31 | 1995-09-01 | Rhone Poulenc Rorer Sa | Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant. |
| DE19535571A1 (de) * | 1995-09-14 | 1997-03-20 | Boehringer Mannheim Gmbh | Pharmazeutische Kombinationspräparate und deren Verwendung zur Behandlung von Hämodialysepatienten |
| EP0868172B1 (en) * | 1995-12-21 | 2002-02-27 | Smithkline Beecham Corporation | Direct compression carbonyl iron tablet |
| US5952226A (en) * | 1996-11-05 | 1999-09-14 | Modex Therapeutiques | Hypoxia responsive EPO producing cells |
| NZ337465A (en) | 1997-03-18 | 2002-04-26 | Roche Diagnostics Gmbh | Pharmaceutical containing erythropoietin and iron preparations for treating haemodialysis patients or anaemias |
| US7033774B2 (en) * | 1997-04-21 | 2006-04-25 | Glycozyme, Inc. | Determination of recombinant glycosylated proteins and peptides in biological fluids |
| EP0885613A1 (de) * | 1997-06-21 | 1998-12-23 | Roche Diagnostics GmbH | Verwendung von modifizierten Hämoglobinen zur Behandlung von Anämien und Kombinationspräparate umfassend Erythropoietin und modifiziertes Hämoglobin |
| JP2002509077A (ja) | 1998-02-09 | 2002-03-26 | ユニヴァースティ オブ サザーン カリフォルニア | 赤血球形成促進方法 |
| US7304150B1 (en) | 1998-10-23 | 2007-12-04 | Amgen Inc. | Methods and compositions for the prevention and treatment of anemia |
| JP2003523940A (ja) | 1999-05-11 | 2003-08-12 | オーソ−マクネイル ファーマシューティカル インコーポレイテッド | エリスロポエチン投与の薬物速度論的および薬力学的モデリング |
| US7459435B2 (en) | 2002-08-29 | 2008-12-02 | Hoffmann-La Roche Inc. | Treatment of disturbances of iron distribution |
| DE10249552A1 (de) | 2002-10-23 | 2004-05-13 | Vifor (International) Ag | Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel |
| US7459436B2 (en) | 2002-11-22 | 2008-12-02 | Hoffmann-La Roche Inc. | Treatment of disturbances of iron distribution |
| EP3081219A1 (en) | 2006-01-06 | 2016-10-19 | Luitpold Pharmaceuticals, Inc. | Methods and compositions for administration of iron |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57149228A (en) * | 1981-03-11 | 1982-09-14 | Ajinomoto Co Inc | Novel erythropoietin and its preparation |
| US4745099A (en) * | 1985-02-06 | 1988-05-17 | Chugai Seiyaku Kabushiki Kaisha | Pharmaceutical composition for the treatment of the anemia of malignant tumors |
| US4732889A (en) * | 1985-02-06 | 1988-03-22 | Chugai Seiyaku Kabushiki Kaisha | Pharmaceutical composition for the treatment of the anemia of rheumatoid arthritis |
| JPS6231A (ja) * | 1985-02-06 | 1987-01-06 | Chugai Pharmaceut Co Ltd | 腎性貧血治療剤 |
| GB2177914B (en) * | 1985-06-04 | 1989-10-25 | Chugai Pharmaceutical Co Ltd | A pharmaceutical composition containing human erythropoietin and a surface active agent for nasal administration for the treatment of anemia |
| US5013718A (en) * | 1986-11-21 | 1991-05-07 | Amgen, Inc. | Method for treating iron overload using EPO |
| JPS63227527A (ja) * | 1987-03-05 | 1988-09-21 | キリン―アムジエン(デラウエア)インコーポレーテツド | 貧血予防薬 |
-
1988
- 1988-04-07 JP JP63084212A patent/JP2858752B2/ja not_active Expired - Lifetime
- 1988-04-07 NO NO881507A patent/NO881507D0/no unknown
- 1988-04-07 KR KR1019880003863A patent/KR880012235A/ko not_active Withdrawn
- 1988-04-08 ES ES88303185T patent/ES2035279T3/es not_active Expired - Lifetime
- 1988-04-08 AT AT88303185T patent/ATE70978T1/de not_active IP Right Cessation
- 1988-04-08 DK DK194288A patent/DK167903B1/da not_active IP Right Cessation
- 1988-04-08 PT PT87197A patent/PT87197B/pt not_active IP Right Cessation
- 1988-04-08 EP EP88303185A patent/EP0286439B1/en not_active Expired - Lifetime
- 1988-04-08 AU AU14445/88A patent/AU613905B2/en not_active Expired
- 1988-04-08 IE IE106488A patent/IE61008B1/en not_active IP Right Cessation
- 1988-04-08 DE DE8888303185T patent/DE3867285D1/de not_active Expired - Lifetime
-
1989
- 1989-09-19 US US07/409,223 patent/US5541158A/en not_active Expired - Lifetime
-
1992
- 1992-03-18 GR GR920400469T patent/GR3004071T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO881507D0 (no) | 1988-04-07 |
| AU1444588A (en) | 1988-10-13 |
| ATE70978T1 (de) | 1992-01-15 |
| JPS63277630A (ja) | 1988-11-15 |
| DE3867285D1 (de) | 1992-02-13 |
| ES2035279T3 (es) | 1995-04-01 |
| JP2858752B2 (ja) | 1999-02-17 |
| EP0286439B1 (en) | 1992-01-02 |
| PT87197B (pt) | 1992-07-31 |
| EP0286439A1 (en) | 1988-10-12 |
| DK167903B1 (da) | 1994-01-03 |
| DK194288A (da) | 1988-10-11 |
| AU613905B2 (en) | 1991-08-15 |
| GR3004071T3 (pt) | 1993-03-31 |
| KR880012235A (ko) | 1988-11-26 |
| IE881064L (en) | 1988-10-09 |
| US5541158A (en) | 1996-07-30 |
| DK194288D0 (da) | 1988-04-08 |
| IE61008B1 (en) | 1994-09-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Patent granted, date of granting |
Effective date: 19920124 |
|
| MM4A | Annulment/lapse due to non-payment of fees, searched and examined patent |
Free format text: MAXIMUM VALIDITY LIMIT REACHED Effective date: 20080408 |