PT87625A - 1-/(phenothiazin-10-yl)alkyl/-alpha-phenyl-4-piperidinemethanols a process for their preparation and their use as medicaments - Google Patents

1-/(phenothiazin-10-yl)alkyl/-alpha-phenyl-4-piperidinemethanols a process for their preparation and their use as medicaments

Info

Publication number
PT87625A
PT87625A PT87625A PT8762588A PT87625A PT 87625 A PT87625 A PT 87625A PT 87625 A PT87625 A PT 87625A PT 8762588 A PT8762588 A PT 8762588A PT 87625 A PT87625 A PT 87625A
Authority
PT
Portugal
Prior art keywords
piperidinemethanols
phenothiazin
medicines
alpha
phenyl
Prior art date
Application number
PT87625A
Other languages
English (en)
Other versions
PT87625B (pt
Inventor
Grover Cleveland Helsley
Larry Davis
Gordon E Olsen
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of PT87625A publication Critical patent/PT87625A/pt
Publication of PT87625B publication Critical patent/PT87625B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
PT87625A 1987-06-01 1988-05-31 Processo para a preparacao de 1-{(fenotiazin-10-il)-alquil}-alfa-fenil-4-piperidinometanois PT87625B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/056,199 US4822796A (en) 1987-06-01 1987-06-01 1-((Phenothiazin-10-yl)alkyl)-alpha-phenyl-4-piperidinemethanols and pharmaceutical use

Publications (2)

Publication Number Publication Date
PT87625A true PT87625A (pt) 1988-06-01
PT87625B PT87625B (pt) 1992-09-30

Family

ID=22002839

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87625A PT87625B (pt) 1987-06-01 1988-05-31 Processo para a preparacao de 1-{(fenotiazin-10-il)-alquil}-alfa-fenil-4-piperidinometanois

Country Status (5)

Country Link
US (1) US4822796A (pt)
EP (1) EP0293813A1 (pt)
JP (1) JPS6445384A (pt)
DK (1) DK295388A (pt)
PT (1) PT87625B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999031058A1 (en) * 1997-12-17 1999-06-24 Novo Nordisk A/S Novel heterocyclic compounds
US6048856A (en) * 1997-12-17 2000-04-11 Novo Nordisk A/S Heterocyclic compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1216268A (fr) * 1958-04-24 1960-04-25 Rhone Poulenc Sa Nouveaux dérivés de la phénothiazine à chaîne pipéridine substituée par une fonction amide et leur préparation
US3000885A (en) * 1958-08-07 1961-09-19 Searle & Co 2-acyl-10-oxyalkylpiperidinoalkylphenothiazines and process
US3063996A (en) * 1959-03-02 1962-11-13 Smith Kline French Lab Substituted piperidinylalkyl phenothiazines
DE1159954B (de) * 1961-11-25 1963-12-27 Boehringer & Soehne Gmbh Verfahren zur Herstellung neuer 10-(Alkoxypiperidinopropyl)-phenthiazine und ihrer Salze
GB1178623A (en) * 1966-05-10 1970-01-21 Sandoz Ltd Phenothiazine Derivatives
US4018922A (en) * 1971-05-14 1977-04-19 Roussel-Uclaf 10-(Piperidin o-alkyl)-phenothiazines
ZA733261B (en) * 1972-06-23 1974-04-24 Lepetit Spa Diphenylmethane derivatives
US4021552A (en) * 1975-06-27 1977-05-03 A. H. Robins Company, Incorporated 10-[ω-(BENZOYLPIPERIDINYL)ALKYL]PHENOTHIAZINES

Also Published As

Publication number Publication date
JPS6445384A (en) 1989-02-17
US4822796A (en) 1989-04-18
PT87625B (pt) 1992-09-30
EP0293813A1 (en) 1988-12-07
DK295388A (da) 1988-12-02
DK295388D0 (da) 1988-05-31

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19920318

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19930930