PT87895A - Processo para a preparacao de esteres e glicosidos derivados de castanospermina ({1s-(1 alfa, 6 beta, 7 alfa, 8 beta, 8a beta)}-octahidro-1,6,7,8-indolizinotetrol) e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de esteres e glicosidos derivados de castanospermina ({1s-(1 alfa, 6 beta, 7 alfa, 8 beta, 8a beta)}-octahidro-1,6,7,8-indolizinotetrol) e de composicoes farmaceuticas que os contem

Info

Publication number: PT87895A
Authority: PT; Portugal
Prior art keywords: beta; alpha; indolizinotetrol; octahidro; castanospermine
Prior art date: 1987-07-02

Application number

PT87895A

Other languages

English (en)

Other versions

PT87895B (pt

Inventor

Paul Saiho Liu

Barry Lee Rhinehart

John K Daniel

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-07-02

Filing date

1988-07-01

Publication date

1989-06-30

1988-07-01 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1989-06-30 Publication of PT87895A publication Critical patent/PT87895A/pt

1995-03-01 Publication of PT87895B publication Critical patent/PT87895B/pt

Links

JDVVGAQPNNXQDW-WCMLQCRESA-N Castanospermine Natural products O[C@H]1[C@@H](O)[C@H]2[C@@H](O)CCN2C[C@H]1O JDVVGAQPNNXQDW-WCMLQCRESA-N 0.000 title 1
JDVVGAQPNNXQDW-TVNFTVLESA-N Castinospermine Chemical compound C1[C@H](O)[C@@H](O)[C@H](O)[C@H]2[C@@H](O)CCN21 JDVVGAQPNNXQDW-TVNFTVLESA-N 0.000 title 1
229930182470 glycoside Natural products 0.000 title 1
150000002338 glycosides Chemical class 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Diabetes (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Hematology (AREA)
Bioinformatics & Cheminformatics (AREA)
Endocrinology (AREA)
Animal Behavior & Ethology (AREA)
Emergency Medicine (AREA)
Obesity (AREA)
Veterinary Medicine (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Saccharide Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

PT87895A 1987-07-02 1988-07-01 Processo para a preparacao de esteres e glicosidos derivados de castanospermina ({1s-(1 alfa, 6 beta, 7 alfa, 8 beta, 8a beta)}-octahidro-1,6,7,8-indolizinotetrol) e de composicoes farmaceuticas que os contem PT87895B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US6935187A	1987-07-02	1987-07-02

Publications (2)

Publication Number	Publication Date
PT87895A true PT87895A (pt)	1989-06-30
PT87895B PT87895B (pt)	1995-03-01

Family

ID=22088386

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT87895A PT87895B (pt)	1987-07-02	1988-07-01	Processo para a preparacao de esteres e glicosidos derivados de castanospermina ({1s-(1 alfa, 6 beta, 7 alfa, 8 beta, 8a beta)}-octahidro-1,6,7,8-indolizinotetrol) e de composicoes farmaceuticas que os contem

Country Status (20)

Country	Link
EP (1)	EP0297534B1 (pt)
JP (1)	JP2683915B2 (pt)
KR (1)	KR970002636B1 (pt)
CN (2)	CN1020609C (pt)
AR (1)	AR245128A1 (pt)
AT (1)	ATE116318T1 (pt)
AU (1)	AU609146B2 (pt)
CA (1)	CA1315276C (pt)
DE (1)	DE3852579T2 (pt)
DK (1)	DK171053B1 (pt)
ES (1)	ES2068816T3 (pt)
FI (1)	FI87072C (pt)
GR (1)	GR3015303T3 (pt)
HU (1)	HU199470B (pt)
IE (1)	IE65164B1 (pt)
IL (1)	IL86928A (pt)
NO (1)	NO167664C (pt)
NZ (1)	NZ225198A (pt)
PT (1)	PT87895B (pt)
ZA (1)	ZA884587B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5004746A (en) *	1987-09-29	1991-04-02	Merrell Dow Pharmaceuticals Inc.	Anti-retroviral castanospermine esters
US4952585A (en) *	1988-12-15	1990-08-28	Merrell Dow Pharmaceuticals Inc.	Castanospermine esters in the inhibition of tumor metastasis
US5214050A (en) *	1989-10-17	1993-05-25	Merrell Dow Pharmaceuticals Inc.	Esters of castanospermine in the treatment of cerebral malaria
AU628228B2 (en) *	1989-10-17	1992-09-10	Merrell Dow Pharmaceuticals Inc.	Esters of castanospermine in the treatment of cerebral malaria
GB8924292D0 (en) *	1989-10-27	1989-12-13	Novalal Ltd	The production of a novel dimer chemical product"novo dimers"by the polymersation of indolizidine alkaloids using cyclo dextrin glucosyl transferase
US5066807A (en) *	1990-03-12	1991-11-19	Merrell Dow Pharmaceuticals Inc.	Process for the preparation of castanospermine
US5028614A (en) *	1990-03-30	1991-07-02	Merrell Dow Pharmaceuticals Inc.	Hydroxymethyl-indolizidines and quinolizidines and their use as α-glucosidase I inhibitors
US5079254A (en) *	1990-06-04	1992-01-07	Merrell Dow Pharmaceuticals Inc.	Derivatives of 6-aminooctahydroindolizinetriol
CA2287316C (en) *	1997-05-22	2005-02-08	Hoechst Marion Roussel, Inc.	Process for preparing 6-o-monoesters of castanospermine
GB0110832D0 (en)	2001-05-03	2001-06-27	Virogen Ltd	Antiviral compounds
US20060052414A1 (en) *	2004-08-13	2006-03-09	Migenix, Inc.	Compositions and methods for treating or preventing Hepadnaviridae infection
DE102020212985B3 (de)	2020-10-14	2021-10-21	Danfoss Power Solutions Gmbh & Co. Ohg	Hydraulischer ventilblock sowie hydraulikeinheit für geschlossene kreislaufanwendungen

1988
- 1988-06-23 CA CA000570177A patent/CA1315276C/en not_active Expired - Fee Related
- 1988-06-27 ZA ZA884587A patent/ZA884587B/xx unknown
- 1988-06-28 AU AU18448/88A patent/AU609146B2/en not_active Ceased
- 1988-06-28 NZ NZ225198A patent/NZ225198A/xx unknown
- 1988-06-28 AR AR88311256A patent/AR245128A1/es active
- 1988-06-29 EP EP88110367A patent/EP0297534B1/en not_active Expired - Lifetime
- 1988-06-29 ES ES88110367T patent/ES2068816T3/es not_active Expired - Lifetime
- 1988-06-29 AT AT88110367T patent/ATE116318T1/de not_active IP Right Cessation
- 1988-06-29 DE DE3852579T patent/DE3852579T2/de not_active Expired - Fee Related
- 1988-06-30 HU HU883388A patent/HU199470B/hu not_active IP Right Cessation
- 1988-06-30 IL IL86928A patent/IL86928A/xx not_active IP Right Cessation
- 1988-07-01 NO NO882940A patent/NO167664C/no unknown
- 1988-07-01 PT PT87895A patent/PT87895B/pt not_active IP Right Cessation
- 1988-07-01 IE IE202188A patent/IE65164B1/en not_active IP Right Cessation
- 1988-07-01 JP JP63165792A patent/JP2683915B2/ja not_active Expired - Fee Related
- 1988-07-01 KR KR1019880008166A patent/KR970002636B1/ko not_active Expired - Fee Related
- 1988-07-01 DK DK366888A patent/DK171053B1/da not_active IP Right Cessation
- 1988-07-01 FI FI883164A patent/FI87072C/fi not_active IP Right Cessation
- 1988-07-02 CN CN88104045A patent/CN1020609C/zh not_active Expired - Fee Related
1992
- 1992-04-09 CN CN92102618A patent/CN1027264C/zh not_active Expired - Fee Related
1995
- 1995-03-03 GR GR950400481T patent/GR3015303T3/el unknown

Also Published As

Publication number	Publication date
DK366888D0 (da)	1988-07-01
ES2068816T3 (es)	1995-05-01
DE3852579D1 (de)	1995-02-09
HUT47572A (en)	1989-03-28
NO882940D0 (no)	1988-07-01
NO882940L (no)	1989-01-03
EP0297534A3 (en)	1990-01-10
NO167664C (no)	1991-11-27
FI883164A7 (fi)	1989-01-03
AR245128A1 (es)	1993-12-30
CN1030418A (zh)	1989-01-18
ZA884587B (en)	1989-03-29
DE3852579T2 (de)	1995-05-04
EP0297534B1 (en)	1994-12-28
NZ225198A (en)	1989-12-21
DK366888A (da)	1989-01-03
DK171053B1 (da)	1996-05-06
ATE116318T1 (de)	1995-01-15
GR3015303T3 (en)	1995-06-30
IL86928A0 (en)	1988-11-30
FI883164A0 (fi)	1988-07-01
AU609146B2 (en)	1991-04-26
KR890002147A (ko)	1989-04-08
KR970002636B1 (ko)	1997-03-07
AU1844888A (en)	1989-01-05
CA1315276C (en)	1993-03-30
JPS6479179A (en)	1989-03-24
IL86928A (en)	1992-08-18
EP0297534A2 (en)	1989-01-04
IE65164B1 (en)	1995-10-04
NO167664B (no)	1991-08-19
FI87072B (fi)	1992-08-14
CN1020609C (zh)	1993-05-12
IE882021L (en)	1989-01-02
CN1027264C (zh)	1995-01-04
CN1065066A (zh)	1992-10-07
FI87072C (fi)	1992-11-25
HU199470B (en)	1990-02-28
JP2683915B2 (ja)	1997-12-03
PT87895B (pt)	1995-03-01

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Legal Events

Date

Code

Title

Description

1995-03-01

FG3A

Patent granted, date of granting

Effective date: 19940818

2004-05-31

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20040229