PT87928A - Processo para a preparacao de novos acidos 3,5-dihidroxi-carboxilicos e dos seus derivados - Google Patents

Processo para a preparacao de novos acidos 3,5-dihidroxi-carboxilicos e dos seus derivados

Info

Publication number: PT87928A
Authority: PT; Portugal
Prior art keywords: alkyl; opt; new; substd; cpds
Prior art date: 1987-07-10

Application number

PT87928A

Other languages

English (en)

Other versions

PT87928B (pt

Inventor

Gerhard Beck

Ernold Granzer

Wilhelm Bartmann

Gunther Wess

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-07-10

Filing date

1988-07-07

Publication date

1989-06-30

1988-07-07 Application filed by Hoechst Ag filed Critical Hoechst Ag

1989-06-30 Publication of PT87928A publication Critical patent/PT87928A/pt

1995-05-04 Publication of PT87928B publication Critical patent/PT87928B/pt

Links

125000000217 alkyl group Chemical group 0.000 abstract 7
YLQBMQCUIZJEEH-UHFFFAOYSA-N Furan Chemical compound C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 abstract 4
YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical compound C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 abstract 4
125000000753 cycloalkyl group Chemical group 0.000 abstract 3
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
125000003545 alkoxy group Chemical group 0.000 abstract 2
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
125000001624 naphthyl group Chemical group 0.000 abstract 2
229930192474 thiophene Natural products 0.000 abstract 2
-1 2,3-dihydroxypropyl Chemical group 0.000 abstract 1
QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000007513 acids Chemical class 0.000 abstract 1
150000001768 cations Chemical class 0.000 abstract 1
125000000816 ethylene group Chemical group [H]C([H])([*:1])C([H])([H])[*:2] 0.000 abstract 1
125000001475 halogen functional group Chemical group 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
150000002596 lactones Chemical class 0.000 abstract 1
239000002184 metal Substances 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/52—Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/40—Halogenated unsaturated alcohols
- C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
- C07C33/48—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts with unsaturation outside the aromatic rings
- C07C33/486—Polycyclic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Hematology (AREA)
Diabetes (AREA)
Obesity (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Furan Compounds (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Pyrane Compounds (AREA)

PT87928A 1987-07-10 1988-07-07 Processo para a preparacao de novos acidos 3,5-dihidroxi-carboxilicos e dos seus derivados PT87928B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19873722807 DE3722807A1 (de)	1987-07-10	1987-07-10	Neue 3,5-dihydroxycarbonsaeuren und deren derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte

Publications (2)

Publication Number	Publication Date
PT87928A true PT87928A (pt)	1989-06-30
PT87928B PT87928B (pt)	1995-05-04

Family

ID=6331292

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT87928A PT87928B (pt)	1987-07-10	1988-07-07	Processo para a preparacao de novos acidos 3,5-dihidroxi-carboxilicos e dos seus derivados

Country Status (17)

Country	Link
EP (1)	EP0306649B1 (pt)
JP (1)	JPS6445337A (pt)
KR (1)	KR890001941A (pt)
AT (1)	ATE73123T1 (pt)
AU (1)	AU606712B2 (pt)
DE (2)	DE3722807A1 (pt)
DK (1)	DK383988A (pt)
ES (1)	ES2031959T3 (pt)
FI (1)	FI90412C (pt)
GR (1)	GR3004588T3 (pt)
HU (1)	HU199768B (pt)
IL (1)	IL87035A0 (pt)
NO (1)	NO167795C (pt)
NZ (1)	NZ225343A (pt)
PH (1)	PH27496A (pt)
PT (1)	PT87928B (pt)
ZA (1)	ZA884920B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5151545A (en) *	1987-10-13	1992-09-29	Pfizer Inc.	3,5-dihydroxy-6,8-nonadienoic acids and derivatives as hypocholesterolemic agents
DE3826814A1 (de) *	1988-08-06	1990-02-08	Hoechst Ag	Neue 6-fluor-3,5-dihydroxycarbonsaeuren und deren derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte
DE3832570A1 (de) *	1988-09-24	1990-03-29	Hoechst Ag	7-substituierte derivate der 3,5-dihydroxyhept-6-insaeure, verfahren zur ihrer herstellung, ihre verwendung als arzneimittel, sowie zwischenprodukte
EP0430129A3 (en) *	1989-11-30	1992-02-26	Tanabe Seiyaku Co., Ltd.	Novel phenylethylene derivatives, processes for preparing the same and intermediates therefor
JP3233403B2 (ja) *	1991-06-19	2001-11-26	塩野義製薬株式会社	光学活性な中間体および該製造法
JP2006519874A (ja) *	2003-03-05	2006-08-31	セルジーン・コーポレーション	ジフェニルエチレン化合物およびその使用
EP2072729B1 (en) *	2007-12-21	2013-06-26	IVECO S.p.A.	Hinge for vehicle door, in particular of a van

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL102791C (pt) *	1957-08-01
BE634738A (pt) *	1962-07-11	1900-01-01
US3919304A (en) *	1968-10-25	1975-11-11	Ciba Geigy Corp	{62 -Hydroxy-{62 -(cycloalkenylphenyl)alkanoic acids, esters and salts
BE793686A (fr) *	1972-01-07	1973-07-04	Beecham Group Ltd	Composes di-aryliques biologiquement actifs
DE2212948A1 (de) *	1972-03-17	1973-09-20	Basf Ag	Verfahren zur herstellung von in alpha-stellung verzweigten alpha,betaungesaettigten aldehyden
JPS5559140A (en) *	1978-10-30	1980-05-02	Sankyo Co Ltd	3,5-dihydroxypentanoic alkyl ester derivative, its preparation and remedy for hyperlipemia containing the same as the effective component
US4341910A (en) *	1979-01-25	1982-07-27	Texas Alkyls, Inc.	Preparation of unsaturated alcohols
US4459422A (en) *	1979-08-17	1984-07-10	Merck & Co., Inc.	Substituted pyranone inhibitors of cholesterol synthesis
US4567289A (en) *	1979-08-17	1986-01-28	Merck & Co., Inc.	Substituted pyranone inhibitors of cholesterol synthesis
DE2934251A1 (de) *	1979-08-24	1981-03-26	Basf Ag, 67063 Ludwigshafen	Verfahren zur herstellung von ungesaettigten alkoholen.
DE3160641D1 (en) *	1980-05-13	1983-08-25	Ciba Geigy Ag	Process for the preparation of benzene or naphthalene alkenyl carboxylic acid derivatives
FI77839C (fi) *	1982-05-27	1989-05-10	Farmos Oy	Foerfarande foer framstaellning av nya terapeutiskt effektiva trifenylalkan- och alkenderivat.
JPS59163336A (ja) *	1983-03-09	1984-09-14	Nippon Petrochem Co Ltd	アルデヒドの製造法
HUT39142A (en) *	1984-07-24	1986-08-28	Sandoz Ag	Process for producing naphtyl-analogues of mevalolactone and derivatives and pharmaceutical compositions containing them
DE3523181A1 (de) *	1985-06-28	1987-01-08	Basf Ag	Verfahren zur herstellung von 2-methyl-2-alkenalen
US4611081A (en) *	1985-07-05	1986-09-09	Merck & Co., Inc.	Process for the preparation of HMG-CoA reductase inhibitors intermediates
US4745229A (en) *	1986-02-28	1988-05-17	Kuraray Company Ltd.	Process for preparing α, β-unsaturated aldehydes

1987
- 1987-07-10 DE DE19873722807 patent/DE3722807A1/de not_active Withdrawn
1988
- 1988-07-07 DE DE8888110833T patent/DE3868794D1/de not_active Expired - Fee Related
- 1988-07-07 EP EP88110833A patent/EP0306649B1/de not_active Expired - Lifetime
- 1988-07-07 FI FI883248A patent/FI90412C/fi not_active IP Right Cessation
- 1988-07-07 AT AT88110833T patent/ATE73123T1/de not_active IP Right Cessation
- 1988-07-07 PT PT87928A patent/PT87928B/pt not_active IP Right Cessation
- 1988-07-07 ES ES198888110833T patent/ES2031959T3/es not_active Expired - Lifetime
- 1988-07-08 NO NO883071A patent/NO167795C/no unknown
- 1988-07-08 AU AU18881/88A patent/AU606712B2/en not_active Ceased
- 1988-07-08 DK DK383988A patent/DK383988A/da not_active Application Discontinuation
- 1988-07-08 JP JP63169158A patent/JPS6445337A/ja active Pending
- 1988-07-08 NZ NZ225343A patent/NZ225343A/xx unknown
- 1988-07-08 PH PH37204A patent/PH27496A/en unknown
- 1988-07-08 ZA ZA884920A patent/ZA884920B/xx unknown
- 1988-07-08 IL IL87035A patent/IL87035A0/xx unknown
- 1988-07-09 HU HU883596A patent/HU199768B/hu not_active IP Right Cessation
- 1988-07-09 KR KR1019880008547A patent/KR890001941A/ko not_active Ceased
1992
- 1992-05-13 GR GR920400794T patent/GR3004588T3/el unknown

Also Published As

Publication number	Publication date
FI90412C (fi)	1994-02-10
HU199768B (en)	1990-03-28
DK383988D0 (da)	1988-07-08
GR3004588T3 (pt)	1993-04-28
ES2031959T3 (es)	1993-01-01
EP0306649B1 (de)	1992-03-04
NO167795C (no)	1991-12-11
PT87928B (pt)	1995-05-04
FI90412B (fi)	1993-10-29
AU606712B2 (en)	1991-02-14
HUT47237A (en)	1989-02-28
EP0306649A1 (de)	1989-03-15
DK383988A (da)	1989-01-11
IL87035A0 (en)	1988-12-30
AU1888188A (en)	1989-01-12
DE3868794D1 (de)	1992-04-09
NO883071D0 (no)	1988-07-08
ATE73123T1 (de)	1992-03-15
KR890001941A (ko)	1989-04-06
PH27496A (en)	1993-07-23
FI883248A0 (fi)	1988-07-07
NO883071L (no)	1989-01-11
NO167795B (no)	1991-09-02
JPS6445337A (en)	1989-02-17
NZ225343A (en)	1991-02-26
ZA884920B (en)	1989-01-17
DE3722807A1 (de)	1989-01-19
FI883248A7 (fi)	1989-01-11

Legal Events

Date

Code

Title

Description

1995-05-04

FG3A

Patent granted, date of granting

Effective date: 19941003

1996-08-30

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19960430

Publication	Publication Date	Title
ES462062A1 (es)	1978-06-16	Un procedimiento para la preparacion de nuevos derivados de tetrahidroisoquinoleina.
ES2054826T3 (es)	1994-08-16	Peptidos con actividad inhibidora de colagenasa.
AR246969A1 (es)	1994-10-31	Un procedimiento para la preparacion de derivados racemicos u opticamente activos de pirido¡1,2-a¿pirazina.
DK0452392T3 (da)	1995-07-03	Heterocycliske chelatiseringsmidler
PT87928A (pt)	1989-06-30	Processo para a preparacao de novos acidos 3,5-dihidroxi-carboxilicos e dos seus derivados
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