PT892802E - Espiro¬ciclopent(b)indol-piperidinas| e intermediarios n-fenil-hidrazina para a sua preparacao sendo ambos inibidores da acetilcolinesterase e da mao - Google Patents

Espiro¬ciclopent(b)indol-piperidinas| e intermediarios n-fenil-hidrazina para a sua preparacao sendo ambos inibidores da acetilcolinesterase e da mao

Info

Publication number
PT892802E
PT892802E PT97908068T PT97908068T PT892802E PT 892802 E PT892802 E PT 892802E PT 97908068 T PT97908068 T PT 97908068T PT 97908068 T PT97908068 T PT 97908068T PT 892802 E PT892802 E PT 892802E
Authority
PT
Portugal
Prior art keywords
piperidinas
ciclopent
acetilcolinesterase
espiro
intermediaries
Prior art date
Application number
PT97908068T
Other languages
English (en)
Inventor
Gerard J O'malley
Mark G Palermo
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Publication of PT892802E publication Critical patent/PT892802E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Psychiatry (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
PT97908068T 1996-04-10 1997-03-10 Espiro¬ciclopent(b)indol-piperidinas| e intermediarios n-fenil-hidrazina para a sua preparacao sendo ambos inibidores da acetilcolinesterase e da mao PT892802E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63064196A 1996-04-10 1996-04-10

Publications (1)

Publication Number Publication Date
PT892802E true PT892802E (pt) 2004-03-31

Family

ID=24527997

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97908068T PT892802E (pt) 1996-04-10 1997-03-10 Espiro¬ciclopent(b)indol-piperidinas| e intermediarios n-fenil-hidrazina para a sua preparacao sendo ambos inibidores da acetilcolinesterase e da mao

Country Status (18)

Country Link
EP (1) EP0892802B1 (pt)
JP (1) JP3615225B2 (pt)
KR (1) KR100270145B1 (pt)
CN (1) CN1233249A (pt)
AR (1) AR006553A1 (pt)
AT (1) ATE252581T1 (pt)
AU (1) AU708124B2 (pt)
BR (1) BR9708563A (pt)
CA (1) CA2251545C (pt)
DE (1) DE69725713T2 (pt)
DK (1) DK0892802T3 (pt)
ES (1) ES2207718T3 (pt)
HU (1) HUP9902755A3 (pt)
IL (1) IL126003A0 (pt)
NO (1) NO984739L (pt)
PT (1) PT892802E (pt)
WO (1) WO1997037992A2 (pt)
ZA (1) ZA972984B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0104493A3 (en) 1998-09-30 2002-12-28 Takeda Pharmaceutical Drugs for improving vesical excretory strength
KR20120123089A (ko) 2010-02-16 2012-11-07 화이자 인코포레이티드 5-ＨＴ₄ 수용체의 부분 효능제인 (Ｒ)-4-((4-((4-(테트라히드로푸란-3-일옥시)벤조［ｄ］이속사졸-3-일옥시)메틸)피페리딘-1-일)메틸)테트라히드로-2Ｈ-피란-4-올
RU2746188C2 (ru) 2015-11-12 2021-04-08 Афаски, Инк. Ингибиторы ионного канала, фармацевтические составы и применение
WO2020048827A1 (en) 2018-09-03 2020-03-12 Bayer Aktiengesellschaft 1, 3, 9-triazaspiro[5.5] undecan-2-one compounds
AR116020A1 (es) 2018-09-03 2021-03-25 Bayer Ag COMPUESTOS DE 3,9-DIAZAESPIRO[5.5]UNDECANO COMO INHIBIDORES DE GGTasa I Y SU USO PARA EL TRATAMIENTO DE ENFERMEDADES HIPERPROLIFERATIVAS
WO2020048828A1 (en) 2018-09-03 2020-03-12 Bayer Pharma Aktiengesellschaft 5-heteroaryl-3,9-diazaspiro[5.5]undecane compounds

Also Published As

Publication number Publication date
CA2251545A1 (en) 1997-10-16
NO984739L (no) 1998-12-09
CN1233249A (zh) 1999-10-27
HUP9902755A3 (en) 2000-05-29
AU708124B2 (en) 1999-07-29
EP0892802B1 (en) 2003-10-22
DE69725713T2 (de) 2004-05-13
ATE252581T1 (de) 2003-11-15
HUP9902755A2 (hu) 2000-03-28
KR20000005328A (ko) 2000-01-25
JP2002509520A (ja) 2002-03-26
DK0892802T3 (da) 2003-12-01
EP0892802A1 (en) 1999-01-27
BR9708563A (pt) 1999-08-03
IL126003A0 (en) 1999-04-11
NO984739D0 (no) 1998-10-09
WO1997037992A2 (en) 1997-10-16
KR100270145B1 (ko) 2000-11-01
JP3615225B2 (ja) 2005-02-02
AU1990997A (en) 1997-10-29
AR006553A1 (es) 1999-09-08
CA2251545C (en) 2002-01-08
ES2207718T3 (es) 2004-06-01
ZA972984B (en) 1997-11-03
DE69725713D1 (de) 2003-11-27

Similar Documents

Publication Publication Date Title
AU694696B2 (en) Sulfonamides and their use
PT909327E (pt) Eritromicinas e processo para a sua preparacao
PT799866E (pt) Negro-de-fumo e processo para a sua preparacao
PT874846E (pt) Derivados de purina e processos para a sua preparacao
NO976072L (no) Propiofenonderivater og fremgangsmÕte for fremstilling derav
PT836615E (pt) Novos inibidores da trombina sua preparacao e utilizacao
BR9709885A (pt) Dispositivo médico processo para sua manufatura e uso de um copolímero de bloco de estireno
BR9605919A (pt) Catalisadores e processos para sua preparação
BR9607200B1 (pt) biomaterial para uso na cirurgia e processo para a sua produÇço.
PT811006E (pt) Compostos contendo benzopirano e metodos para a sua utilizacao
BR9607375A (pt) Rolos picotados sen núcleo e métodos para sua fabricação e uso
PT1015444E (pt) Derivados de pirimidina e processos para a sua preparacao
PT900253E (pt) Composicoes de betume e um processo para a sua preparacao
PT831098E (pt) Intermediarios e processo para a preparacao de olanzapina
PT934319E (pt) Derivados de 1h-pirido¬3,4-b|indol-4-carboxamida processo para a sua preparacao e a sua aplicacao em terapeutica
BR9600149A (pt) 2-(2-N-alcoxifenil)-purin-6-onas 9-substituídas processo para sua preparação medicamantos e uso
BR9703634A (pt) Poliamidoaminas ligadas silila e processo para a sua preparação
PT755985E (pt) Misturas de corantes, processos para a sua preparacao e sua utilizacao
BR9505899A (pt) Tienopiridonas processo para sua preparação processo para a produção farmacêutica preparação farmacêutica e uso
BR9500068A (pt) Embalagem e método para sua preparação
AU1664299A (en) Autodegradable microcarriers and their use
BR9600779A (pt) Benzenossulfoniluréias e -tioréias substituidas processo para sua preparação uso e medicamento
BR9600773A (pt) Benzenossulfonilurélas ou - tiourélas substituídas processo para sua preparação uso e medicamento
BR9708563A (pt) Espiro [ciclopenti[b]indol-piperidinas] e intermediários n-fenil-hi-drazona para sua preparação ambos sendo inibidores de acetilcolinesterase e mao
BR9703064A (pt) Difosfinas substituídas e um processo para a sua preparação