PT90376A - Processo para a preparacao de peptidos env-codificados de hiv capazes de elicitarem anticorpos que inibem hiv em mamiferos e de anticorpos monoclonais que inibem hiv mediante utilizacao desses peptidos - Google Patents

Processo para a preparacao de peptidos env-codificados de hiv capazes de elicitarem anticorpos que inibem hiv em mamiferos e de anticorpos monoclonais que inibem hiv mediante utilizacao desses peptidos

Info

Publication number
PT90376A
PT90376A PT90376A PT9037689A PT90376A PT 90376 A PT90376 A PT 90376A PT 90376 A PT90376 A PT 90376A PT 9037689 A PT9037689 A PT 9037689A PT 90376 A PT90376 A PT 90376A
Authority
PT
Portugal
Prior art keywords
hiv
peptides
antibodies
codified
env
Prior art date
Application number
PT90376A
Other languages
English (en)
Other versions
PT90376B (pt
Inventor
Stephen Robert Petteway Jr
William Robert Kenealy
Paul John Durda
Original Assignee
Du Pont Merck Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/324,027 external-priority patent/US5562905A/en
Application filed by Du Pont Merck Pharma filed Critical Du Pont Merck Pharma
Publication of PT90376A publication Critical patent/PT90376A/pt
Publication of PT90376B publication Critical patent/PT90376B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/112—Retroviridae (F), e.g. leukemia viruses
    • C07K16/114—Lentivirus (G), e.g. human immunodeficiency virus [HIV], feline immunodeficiency virus [FIV] or simian immunodeficiency virus [SIV]
    • C07K16/1145—Env proteins, e.g. gp41, gp110/120, gp160, V3, principal neutralising domain [PND] or CD4-binding site
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT90376A 1988-04-26 1989-04-26 Processo para a preparacao de peptidos env-codificados de hiv capazes de elicitarem anticorpos que inibem hiv em mamiferos e de anticorpos monoclonais que inibem hiv mediante utilizacao desses peptidos PT90376B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18633388A 1988-04-26 1988-04-26
US07/324,027 US5562905A (en) 1988-04-26 1989-03-20 Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals

Publications (2)

Publication Number Publication Date
PT90376A true PT90376A (pt) 1989-11-10
PT90376B PT90376B (pt) 1995-01-31

Family

ID=26881983

Family Applications (1)

Application Number Title Priority Date Filing Date
PT90376A PT90376B (pt) 1988-04-26 1989-04-26 Processo para a preparacao de peptidos env-codificados de hiv capazes de elicitarem anticorpos que inibem hiv em mamiferos e de anticorpos monoclonais que inibem hiv mediante utilizacao desses peptidos

Country Status (10)

Country Link
EP (1) EP0339504A3 (pt)
JP (1) JPH02160800A (pt)
AU (1) AU632475B2 (pt)
DK (1) DK200189A (pt)
FI (1) FI891957L (pt)
HU (1) HUT51296A (pt)
IL (1) IL90058A0 (pt)
NO (1) NO891711L (pt)
NZ (1) NZ228869A (pt)
PT (1) PT90376B (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990012868A1 (en) * 1989-04-25 1990-11-01 Tanox Biosystems, Inc. Antibodies specific for cd4-binding domain of hiv
WO1990015078A1 (en) * 1989-06-05 1990-12-13 Scott Charles F Jr HUMAN MONOCLONAL ANTIBODIES TO HIV-1MN gp 120
SE9000333D0 (sv) * 1990-01-31 1990-01-31 Britta Wahren Monoklonal antikropp
JP3494300B2 (ja) * 1990-04-03 2004-02-09 ジェネンテック・インコーポレーテッド Ｈｉｖに対する予防接種のための方法および組成物
US7041293B1 (en) 1990-04-03 2006-05-09 Genentech, Inc. HIV env antibodies
AU8007991A (en) * 1990-06-29 1992-01-23 Daniel Zagury Methods of inducing immune response to aids virus
JP2989862B2 (ja) * 1990-07-02 1999-12-13 財団法人化学及血清療法研究所 モノクローナル抗体
US5712373A (en) * 1990-07-02 1998-01-27 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute HIV monoclonal antibody specific for the HTLV-IIImn gp120 envelope glycoprotein
CA2047042A1 (en) * 1990-07-19 1992-01-20 John Hannah Cyclic hiv principal neutralizing determinant peptides
CA2047078A1 (en) * 1990-07-19 1992-01-20 Steven S. Bondy Cyclic hiv principal neutralizing determinant peptides
IL98845A0 (en) * 1990-07-19 1992-07-15 Merck & Co Inc Coconjugate vaccines comprising immunogenic protein,hiv related peptides,and anionic moieties,their preparation and pharmaceutical compositions containing them
IL99077A0 (en) * 1990-08-13 1992-07-15 Merck & Co Inc New embodiments of the hiv principal neutralizing determinant and pharmaceutical compositions containing them
US5627035A (en) * 1990-08-22 1997-05-06 Syntello Vaccine Development Ab Peptides that block human immunodeficiency virus and methods of use thereof
US5346989A (en) * 1990-08-22 1994-09-13 Syntello Vaccine Development Kb Peptides for use in induction of T cell activation against HIV-1
AU662534B2 (en) * 1991-06-03 1995-09-07 Syntello Vaccine Development Ab Peptides for use in induction of T cell activation against HIV-1
WO1993004090A1 (en) * 1991-08-22 1993-03-04 Nissin Shokuhin Kabushiki Kaisha Hiv immunotherapeutics
US5665569A (en) * 1991-08-22 1997-09-09 Nissin Shokuhin Kabushiki Kaisha HIV immunotherapeutics
CA2124691A1 (en) * 1991-12-02 1993-06-10 Jagannadha K. Sastry Compositions for eliciting cytotoxic t-lymphocyte responses against viruses
CA2084180A1 (en) * 1991-12-11 1993-06-12 Paul P. Hung Expression of specific immunogens using viral antigens
JPH0748276A (ja) * 1992-03-26 1995-02-21 Inmeru:Kk Ｈｉｖ感染症予防ワクチンおよびその製造法
WO1993019775A1 (en) * 1992-03-31 1993-10-14 Medimmune, Inc. Administration of liposomes containing peptides or proteins including ctl eptitopes of hiv proteins
AU5359094A (en) * 1992-10-13 1994-05-09 Children's Hospital Oral tolerance and immune suppression in the treatment of aids
US5274122A (en) * 1992-10-15 1993-12-28 Merck & Co., Inc. Acidic derivatives of homocysteine thiolactone
KR100337069B1 (ko) * 1993-03-11 2002-10-11 사이단호진가가쿠오요비겟세이리요호오겐큐쇼 항-hiv모노클로날항체
US6180134B1 (en) 1993-03-23 2001-01-30 Sequus Pharmaceuticals, Inc. Enhanced ciruclation effector composition and method
WO1994028929A1 (en) 1993-06-07 1994-12-22 Genentech, Inc. Hiv envelope polypeptides
EP0723664A1 (en) * 1993-10-15 1996-07-31 Eva M. Rakowicz-Szulczynska Detection and treatment of breast and gynecological cancer
US6585979B1 (en) 1996-07-08 2003-07-01 Genentech, Inc. HIV envelope polypeptides and immunogenic composition
ZA975889B (en) * 1996-07-08 1998-02-23 Genentech Inc HIV envelope polypeptides and vaccine.
FR2874612A1 (fr) * 2004-08-27 2006-03-03 Commissariat Energie Atomique Epitotes t cd4+ du vih restreints a hla-dp4 et leurs applications
EP2778681A1 (en) * 2013-03-15 2014-09-17 Biomay Ag Method for diagnosing a viral infection

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2571968B1 (fr) * 1984-10-18 1989-03-17 Pasteur Institut Virus purifie des lymphadenopathies et du syndrome d'immuno-depression acquise et antigenes d'enveloppe de ce virus, procede d'obtention de ce virus et de ces antigenes d'enveloppe de ce virus, applications de ce virus ou de ces antigenes a la preparation de compositions immunogenes ou pour le diagnostic des susdites affections.
GB8501473D0 (en) * 1985-01-21 1985-02-20 Pasteur Institut Cloned dna sequences
EP0387915B1 (en) * 1984-10-18 1993-03-10 Institut Pasteur F antigens of the human immunodeficiency virus, and their applications
ATE108022T1 (de) * 1985-10-24 1994-07-15 Southwest Found Biomed Res Synthetische peptide und deren verwendung zur diagnose und impfung für aids und arc.
WO1987007616A1 (en) * 1986-06-12 1987-12-17 Biogen N.V. Peptides involved in the pathogenesis of hiv infection
NZ221440A (en) * 1986-08-20 1991-11-26 Genetic Systems Corp Composition containing monoclonal antibodies/peptides useful in treating and diagnosing hiv infections
DE3853779T2 (de) * 1987-05-29 1995-09-07 Baylor College Medicine Hiv-1 neutralisierende monoklonale antikörper.
EP0400076B1 (en) * 1988-01-26 1996-05-15 THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce A synthetic antigen evoking anti-hiv response

Also Published As

Publication number Publication date
FI891957A7 (fi) 1989-10-27
EP0339504A3 (en) 1990-09-12
HUT51296A (en) 1990-04-28
NO891711L (no) 1989-10-27
PT90376B (pt) 1995-01-31
DK200189D0 (da) 1989-04-25
DK200189A (da) 1989-10-27
AU632475B2 (en) 1993-01-07
JPH02160800A (ja) 1990-06-20
EP0339504A2 (en) 1989-11-02
FI891957A0 (fi) 1989-04-25
NO891711D0 (no) 1989-04-25
FI891957L (fi) 1989-10-27
IL90058A0 (en) 1989-12-15
AU3332089A (en) 1989-11-02
NZ228869A (en) 1992-02-25

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FG3A Patent granted, date of granting

Effective date: 19940719

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19960131