PT90601A - Processo para a preparacao de composicoes farmaceuticas com base em derivados de pirimido-(6,1-a)-isoquinolina-4-onas - Google Patents

Processo para a preparacao de composicoes farmaceuticas com base em derivados de pirimido-(6,1-a)-isoquinolina-4-onas

Info

Publication number: PT90601A
Authority: PT; Portugal
Prior art keywords: pyrimido; isokinolin; preparation; pharmaceutical compositions; compositions based
Prior art date: 1988-05-19

Application number

PT90601A

Other languages

English (en)

Other versions

PT90601B (pt

Inventor

Bansi Lal

Richard Helmut Rupp

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-05-19

Filing date

1989-05-18

Publication date

1989-11-30

1989-05-18 Application filed by Hoechst Ag filed Critical Hoechst Ag

1989-11-30 Publication of PT90601A publication Critical patent/PT90601A/pt

1994-09-30 Publication of PT90601B publication Critical patent/PT90601B/pt

Links

239000008194 pharmaceutical composition Substances 0.000 title 1
201000004384 Alopecia Diseases 0.000 abstract 1
230000003779 hair growth Effects 0.000 abstract 1
230000003676 hair loss Effects 0.000 abstract 1
CIVQDIGHVMGTPD-UHFFFAOYSA-N pyrimido[6,1-a]isoquinolin-4-one Chemical class C1=CC=C2C=CN3C(=O)N=CC=C3C2=C1 CIVQDIGHVMGTPD-UHFFFAOYSA-N 0.000 abstract 1
238000005728 strengthening Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Dermatology (AREA)
Birds (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cosmetics (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

PT90601A 1988-05-19 1989-05-18 Processo para a preparacao de composicoes farmaceuticas com base em derivados de pirimido-(6,1-a)-isoquinolina-4-onas PT90601B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE3816995A DE3816995A1 (de)	1988-05-19	1988-05-19	Verwendung von pyrimido-(6,1-a)-isochinolin-4-on-derivaten und medizinische zubereitungen auf basis dieser verbindungen

Publications (2)

Publication Number	Publication Date
PT90601A true PT90601A (pt)	1989-11-30
PT90601B PT90601B (pt)	1994-09-30

Family

ID=6354652

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT90601A PT90601B (pt)	1988-05-19	1989-05-18	Processo para a preparacao de composicoes farmaceuticas com base em derivados de pirimido-(6,1-a)-isoquinolina-4-onas

Country Status (9)

Country	Link
US (1)	US5141936A (pt)
EP (1)	EP0342617B1 (pt)
JP (1)	JPH0217119A (pt)
AT (1)	ATE91881T1 (pt)
DE (2)	DE3816995A1 (pt)
DK (1)	DK242089A (pt)
ES (1)	ES2058382T3 (pt)
IE (1)	IE63241B1 (pt)
PT (1)	PT90601B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE60005493T2 (de) *	1999-03-31	2004-07-01	Vernalis Ltd., Wokingham	Pyrimido[6,1-a]isochinolinonderivate
EP1307201B1 (de) *	2000-08-01	2004-11-24	Bayer HealthCare AG	Selektive pde 2-inhibitoren als arzneimittel zur verbesserung der wahrnehmung
EP1641766A2 (en) *	2003-07-08	2006-04-05	Smithkline Beecham Corporation	Novel chemical compounds
GB201502260D0 (en)	2015-02-11	2015-04-01	Verona Pharma Plc	Salt of Pyrimido[6,1-A]Isoquinolin-4-one compound
US10588906B2 (en) *	2017-08-08	2020-03-17	Seoul National University Hospital	Method of preventing hair loss or promoting hair growth by using phosphodiesterase 3 inhibitor
KR102050537B1 (ko) *	2017-08-08	2019-12-02	서울대학교병원	포스포디에스터라아제 3 억제제를 포함하는 탈모방지 또는 발모촉진용 조성물

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2720085A1 (de) *	1977-05-05	1978-11-16	Hoechst Ag	Pyrimido(6,1-a)isochinolin-2-on- derivate
FI64370C (fi) *	1977-05-05	1983-11-10	Hoechst Ag	Foerfarande foer framstaellning av terapeutiskt anvaendbara pyimido-(6,1-a)isokinolin-2-imino-4-onderivat
IT1201436B (it) *	1985-07-19	1989-02-02	Vincenzo Zappia	Formulazioni topiche a lento rilascio
DE3601739A1 (de) *	1986-01-22	1987-07-23	Wella Ag	Kosmetisches mittel zur behandlung der haare oder der kopfhaut
US4828837A (en) *	1987-03-30	1989-05-09	Liposome Technology, Inc.	Non-crystalline minoxidil composition, its production and application

1988
- 1988-05-19 DE DE3816995A patent/DE3816995A1/de not_active Withdrawn
1989
- 1989-05-17 AT AT89108798T patent/ATE91881T1/de not_active IP Right Cessation
- 1989-05-17 DE DE8989108798T patent/DE58905014D1/de not_active Expired - Fee Related
- 1989-05-17 EP EP89108798A patent/EP0342617B1/de not_active Expired - Lifetime
- 1989-05-17 US US07/353,280 patent/US5141936A/en not_active Expired - Fee Related
- 1989-05-17 ES ES89108798T patent/ES2058382T3/es not_active Expired - Lifetime
- 1989-05-18 JP JP1123015A patent/JPH0217119A/ja active Pending
- 1989-05-18 IE IE161289A patent/IE63241B1/en not_active IP Right Cessation
- 1989-05-18 PT PT90601A patent/PT90601B/pt not_active IP Right Cessation
- 1989-05-18 DK DK242089A patent/DK242089A/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
IE63241B1 (en)	1995-04-05
DK242089A (da)	1989-11-20
PT90601B (pt)	1994-09-30
EP0342617A3 (en)	1990-04-04
JPH0217119A (ja)	1990-01-22
DK242089D0 (da)	1989-05-18
EP0342617B1 (de)	1993-07-28
ATE91881T1 (de)	1993-08-15
US5141936A (en)	1992-08-25
DE58905014D1 (de)	1993-09-02
DE3816995A1 (de)	1989-11-23
IE891612L (en)	1989-11-19
ES2058382T3 (es)	1994-11-01
EP0342617A2 (de)	1989-11-23

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Legal Events

Date

Code

Title

Description

1994-09-30

FG3A

Patent granted, date of granting

Effective date: 19940315

1999-01-29

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19980930